International Journal of Medical Biochemistry最新文献

{"title":"A Point to Consider in the Statistical Analysis of Scientific Studies","authors":"M. Kalaycı","doi":"10.14744/ijmb.2019.80299","DOIUrl":"https://doi.org/10.14744/ijmb.2019.80299","url":null,"abstract":"","PeriodicalId":176166,"journal":{"name":"International Journal of Medical Biochemistry","volume":"136 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"116375987","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Suberoylanilide hydroxamic acid and 3-Deazaneplocın A decrease lncRNA hox transcript antısense RNA in liver fibrosis","authors":"Merve Özel","doi":"10.14744/ijmb.2023.95914","DOIUrl":"https://doi.org/10.14744/ijmb.2023.95914","url":null,"abstract":"","PeriodicalId":176166,"journal":{"name":"International Journal of Medical Biochemistry","volume":"45 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"116400225","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The Effect of Fasting and Non-Fasting on Dynamic Thiol Disulfide Homeostasis","authors":"A. Balik","doi":"10.14744/ijmb.2021.53825","DOIUrl":"https://doi.org/10.14744/ijmb.2021.53825","url":null,"abstract":"","PeriodicalId":176166,"journal":{"name":"International Journal of Medical Biochemistry","volume":"46 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"123798412","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Performance of multi-criteria algorithm based on urinalysis in predicting negative urine culture results","authors":"Didem Barlak Keti","doi":"10.14744/ijmb.2022.89421","DOIUrl":"https://doi.org/10.14744/ijmb.2022.89421","url":null,"abstract":"","PeriodicalId":176166,"journal":{"name":"International Journal of Medical Biochemistry","volume":"38 10 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"125735672","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Sigma metric evaluation with different TEa targets in clinical biochemistry","authors":"Şeniz Korkmaz","doi":"10.14744/ijmb.2022.81300","DOIUrl":"https://doi.org/10.14744/ijmb.2022.81300","url":null,"abstract":"","PeriodicalId":176166,"journal":{"name":"International Journal of Medical Biochemistry","volume":"25 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"128153194","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Comparison of small-volume tubes with vacuum blood tubes for complete blood count","authors":"Kubranur Unal","doi":"10.14744/ijmb.2019.69188","DOIUrl":"https://doi.org/10.14744/ijmb.2019.69188","url":null,"abstract":"25 Unal, Comparison of SVTs and vacuum blood tubes / doi: 10.14744/ijmb.2018.69188 the influence of blood collection tubes on laboratory tests is usually ignored, the correct choice of blood collection tube is essential [5]. Another issue is that the amount of additive placed in a tube is designed for a certain volume of blood. If less blood than required is taken, the excess amount of additive has the potential to adversely affect the accuracy of the test results [6]. Vacuum blood tubes are frequently used in routine practice, and now small-volume tubes (SVTs) containing K2EDTA have been also manufactured. SVTs are suitable for taking samples and the transport and processing of samples in cases where only a small amount of blood is required [7]. To the best of our knowledge, there is no study in the literature that evaluates BD Microtainer K2EDTA and BD Vacutainer K2EDTA tubes (Becton, Dickinson and Company, Franklin Lakes, NJ, USA) using the CBC. The aim of this study was to compare SVTs with vacuum blood tubes for use in performing a CBC. Materials and Methods Subjects and study design A total of 40 healthy adult volunteers ranging in age between 20 and 55 years were included in this study. All of the participants provided written, informed consent. This study was approved by the Ethics Committee of Ankara Polatlı State Hospital. SVTs are designed primarily for capillary blood collection [8]. However, in this study, venous blood collection was used for both tubes. Two venous blood samples from each volunteer were taken from a single cubital region and were collected into BD Vacutainer K2EDTA tubes and BD Microtainer K2EDTA tubes: 1. BD Vacutainer K2EDTA tube: 3 mL (volume), 13×75 mm (size), 5.4 mg EDTA (additive) (Catalog number: 368856). 2. BD Microtainer K2EDTA tube: 250-500 μL (volume), 10×35 mm (size), 0.8 mg EDTA (additive) (Catalog number: 365975). The tubes were filled to capacity. After the blood samples were taken, all of the tubes were immediately mixed with gentle 180° inversion to avoid microclotting. The samples were analyzed 15 to 30 minutes after venipuncture. All of the measurements were performed in duplicate. Methods The cellular count result of the ABX Pentra DF 120 hematological analyzer (Horiba, Ltd., Kyoto, Japan) using electronic impedance variation in 2 different K2 EDTA tubes was evaluated at the Ankara Polatlı Public Hospital Department of Biochemistry Central Laboratory. The following analytes were measured in both tubes for each of the 40 subjects: complete blood count (CBC), red blood cell (RBC), hemoglobin (HGB), hematocrit (HCT), mean corpuscular volume (MCV), mean corpuscular hemoglobin (MCH), mean corpuscular hemoglobin concentration (MCHC), red cell distribution width (RDW), platelet (PLT), white blood cell (WBC) count and differential, including neutrophils (NEU), lymphocytes (LYMPHO), monocytes (MONO), eosinophils (EOS), and basophils (BASO). Internal and external quality control data were checked before the","PeriodicalId":176166,"journal":{"name":"International Journal of Medical Biochemistry","volume":"73 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"127274851","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Soluble FMS-LIKEike Tyrosine Kinase – 1: an overview","authors":"Sathya Selvarajan","doi":"10.14744/ijmb.2023.66933","DOIUrl":"https://doi.org/10.14744/ijmb.2023.66933","url":null,"abstract":"","PeriodicalId":176166,"journal":{"name":"International Journal of Medical Biochemistry","volume":"65 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"130346471","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Acacetin Ameliorates Acetylsalicylic Acid-Induced Gastric Ulcer in Rats by Interfering with Oxidative Stress, Inflammation, and Apoptosis","authors":"H. Şimşek","doi":"10.14744/ijmb.2023.07830","DOIUrl":"https://doi.org/10.14744/ijmb.2023.07830","url":null,"abstract":"which excessive acid and pepsin activity affects the mucosal epithelium and is common worldwide. Gastrointestinal disturbances come to the fore among the side effects observed in the treatment with drugs such as aspirin. Acacetin is a plant-derived flavonoid with intriguing properties such as anti-inflammatory, antioxidant, and anticancer. The aim of the study is to investigate the effects of acacetin in GU model caused by aspirin active ingredient acetylsalicylic acid. Methods: Thirty-two Wistar albino rats were divided into four groups: Control, GU, acacetin, and GU +acacetin. Acetyl-salicylic acid (150 mg/kg) and acacetin (25 mg/kg) were administered intraperitoneally as a single dose. Gastric lesions were examined microscopically and macroscopically. TNF-a, cyclooxygenase-2 (COX-2), and nuclear factor kappa B (NF-kB) for inflammation; Caspase-3 and Bcl-2 for apoptosis, total antioxidant status (TAS), total oxidant status (TOS), and oxidative stress index (OSI) for oxidative stress were analyzed. Results: Bcl-2 and TAS values were decreased, while Tumor necrosis factor-alpha (TNF-α), COX-2, NF-kB, Caspase-3, TOS, and OSI values were increased in the GU group compared to the control group. Bcl-2 and TAS values were increased and TNF-α, COX-2, NF-kB, Caspase-3, TOS, and OSI values were decreased in the GU +acacetin group compared to the GU group. The GU index (GUI) detected in the GU group decreased significantly with the administration of acacetin. Conclusion: High doses of ASA contributed to the formation of GU in the stomach tissue by increasing the levels of inflammation, oxidative stress, and apoptosis, whereas ACA reduced the ulcer damage by reducing the increase in all these pathways.","PeriodicalId":176166,"journal":{"name":"International Journal of Medical Biochemistry","volume":"35 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"131841012","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The relationship between homocysteine and autoimmune subclinical hypothyroidism","authors":"B. Demir","doi":"10.14744/ijmb.2019.13008","DOIUrl":"https://doi.org/10.14744/ijmb.2019.13008","url":null,"abstract":"","PeriodicalId":176166,"journal":{"name":"International Journal of Medical Biochemistry","volume":"103 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"133572460","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Conventional cigarette and electronic nicotine delivery systems exacerbate high-fat diet-induced inflammation and oxidative stress","authors":"Dwi Nur Ahsani","doi":"10.14744/ijmb.2023.99815","DOIUrl":"https://doi.org/10.14744/ijmb.2023.99815","url":null,"abstract":"","PeriodicalId":176166,"journal":{"name":"International Journal of Medical Biochemistry","volume":"5 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"131041664","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}