Journal of UOEH最新文献_第10页

Expression of p11 and TASK1 Channels in Rat Carotid Body Glomus Cells Subjected to Chronic Intermittent Hypoxia. 慢性间歇性缺氧大鼠颈动脉体血管球细胞p11和TASK1通道的表达

Journal of UOEH Pub Date : 2022-01-01 DOI: 10.7888/juoeh.44.249

Hidetada Matsuoka, Mieczyslaw Pokorski, Kotaro Takeda, Yasumasa Okada, Keita Harada, Masumi Inoue

引用次数: 0

A Case Report of Primary Unresectable Hilar Cholangiocarcinoma Causing Colonic Obstruction Due to Peritoneal Dissemination. 原发性不可切除肝门胆管癌腹膜播散致结肠梗阻1例。

Journal of UOEH Pub Date : 2022-01-01 DOI: 10.7888/juoeh.44.277

Atsushi Toyofuku, Hiroaki Kuroda, Kazuma Ito, Akiko Sakurai, Kohei Yoshida, Aiichiro Higure, Shinsaku Yamaguchi, Shinji Yotsumoto, Ken-Ichi Sakita, Naoki Nagata

{"title":"A Case Report of Primary Unresectable Hilar Cholangiocarcinoma Causing Colonic Obstruction Due to Peritoneal Dissemination.","authors":"Atsushi Toyofuku, Hiroaki Kuroda, Kazuma Ito, Akiko Sakurai, Kohei Yoshida, Aiichiro Higure, Shinsaku Yamaguchi, Shinji Yotsumoto, Ken-Ichi Sakita, Naoki Nagata","doi":"10.7888/juoeh.44.277","DOIUrl":"https://doi.org/10.7888/juoeh.44.277","url":null,"abstract":"Although surgical resection is the only available treatment to achieve long-term survival in biliary tract cancer, many cases are often identified at an advanced stage at the time of diagnosis. Radiotherapy may be an alternative option to prolong survival in cases with locally advanced unresectable disease. While there are some reports of long-term survival after radiotherapy for unresectable biliary tract cancer, it is rare that clinical symptoms are exhibited by peritoneal dissemination more than 8 years after radiotherapy and that resection can be performed. Our case was a 55-year-old female who had visited with a complaint of jaundice and was diagnosed with primary unresectable hilar cholangiocarcinoma. She received definitve chemoradiotherapy, and repeated receiving maintenance chemotherapy thereafter until clinical manifestation. During follow-up, she was diagnosed with stenosis of the sigmoid colon, which was attributed to peritoneal dissemination of cholangiocarcinoma. We herein report a rare case of primary unresectable hilar cholangiocarcinoma after chemoradiotherapy which was followed by chemotherapy that was controlled for more than 8 years but eventually caused colonic obstruction attributed to peritoneal dissemination.","PeriodicalId":17570,"journal":{"name":"Journal of UOEH","volume":"44 3","pages":"277-286"},"PeriodicalIF":0.0,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"33459476","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

[Vaccination in Workplace and Compensation for Adverse Events]. [工作场所的疫苗接种和不良事件赔偿]。

Journal of UOEH Pub Date : 2022-01-01 DOI: 10.7888/juoeh.44.177

Tatsunori Suemitsu, Shogo Miyazaki, Kazuto Sato, Yutaro Hashimoto

{"title":"[Vaccination in Workplace and Compensation for Adverse Events].","authors":"Tatsunori Suemitsu, Shogo Miyazaki, Kazuto Sato, Yutaro Hashimoto","doi":"10.7888/juoeh.44.177","DOIUrl":"10.7888/juoeh.44.177","url":null,"abstract":"Several types of SARS-Cov-2 vaccine have been quickly developed and officially approved for emergency use in accordance with the Pharmaceutical Act. Mass vaccination in workplaces in Japan was subsequently promoted, targeting health care workers and senior citizens. We overviewed the pathophysiology of COVID-19 and reviewed reports containing fatal outcomes, compensation programs, and remedial measures for health damage after vaccinations, in relation to their relevant legislations. The Immunization Act was amended prior to the mass vaccination to authorize the indemnity agreement between the government and pharmaceutical companies to compensate for losses based on health damages after vaccination. Pursuant to the Civil Code and the State Redress Act, employers reserve the right to obtain reimbursement when they are liable to pay compensation for damages inflicted on a third party. There are no provisions to exclude healthcare workers and occupational health staff who participated in practical procedures from lawsuits and liability. We propose legislative reformation and careful contracts with responsible organizations concerned with emergency vaccinations in order to confront forthcoming new or re-emerging infections beyond this pandemic.","PeriodicalId":17570,"journal":{"name":"Journal of UOEH","volume":"44 2","pages":"177-184"},"PeriodicalIF":0.0,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9563486","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

[A Case of Angioimmunoblastic T-cell Lymphoma (AITL)]. 1例血管免疫母细胞t细胞淋巴瘤(AITL)

Journal of UOEH Pub Date : 2022-01-01 DOI: 10.7888/juoeh.44.293

Ayaka Kaneoka, Yoko Akamatsu, Reiko Hara, Akiko Sugiyama, Mihoko Setoguchi

{"title":"[A Case of Angioimmunoblastic T-cell Lymphoma (AITL)].","authors":"Ayaka Kaneoka, Yoko Akamatsu, Reiko Hara, Akiko Sugiyama, Mihoko Setoguchi","doi":"10.7888/juoeh.44.293","DOIUrl":"https://doi.org/10.7888/juoeh.44.293","url":null,"abstract":"A 84-year-old female noticed erythema over her whole body for several months and was referred to our department for evaluation of her skin eruption. A physical examination revealed millet-sized erythematous papules and macules all over her body, a high body temperature, and a decreased level of consciousness. A laboratory examination showed an elevated white blood cell count (8200/μl), atypical lymphocytes (3%) and sIL-2R (4030U / ml). Computed Tomography showed systemic lymphadenopathy. A lymph node biopsy taken from the left inguinal lymph node revealed destruction of the lymph nodes, enlargement of the high endothelial venules, and atypical lymphocyte infiltration. Based on the clinical findings and laboratory examination, we diagnosed angioimmunoblastic Tcell lymphoma (AITL). AITL is a relatively rare peripheral T-cell lymphoma with severe systemic symptoms such as fever and lymph node swelling. While approximately half of all cases experience skin symptoms, which are one of the initial symptoms, it is difficult to determine the diagnosis due to the various clinical features or many non-specific rashes. We should keep in mind a differential diagnosis of lymphoma in cases of the presence of persistent eruption, systemic symptoms, and the existence of atypical lymphocytes in peripheral blood.","PeriodicalId":17570,"journal":{"name":"Journal of UOEH","volume":"44 3","pages":"293-299"},"PeriodicalIF":0.0,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"33459478","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

[A Case of Occupational Contact Dermatitis Caused by Rubber Gloves]. 橡胶手套致职业性接触性皮炎1例

Journal of UOEH Pub Date : 2022-01-01 DOI: 10.7888/juoeh.44.307

Hikaru Kawahara-Nanamori, Yu Sawada

引用次数: 0

Journal of UOEH Pub Date : 2022-01-01 DOI: 10.7888/juoeh.44.229

Sanpatchaya Sirisawasd, Nontiya Homkham, Sasitorn Taptagaporn, Teeraphun Kaewdok

{"title":"Risk Factors Related to Perceived Hot Conditions on Outdoor Farms Among Thai Elderly Farmers With Chronic Diseases.","authors":"Sanpatchaya Sirisawasd, Nontiya Homkham, Sasitorn Taptagaporn, Teeraphun Kaewdok","doi":"10.7888/juoeh.44.229","DOIUrl":"https://doi.org/10.7888/juoeh.44.229","url":null,"abstract":"Working on outdoor farms affects elderly farmers' health, especially those who have chronic diseases. This study aims to identify the risk factors related to perceived hot conditions on outdoor farms among elderly Thai farmers aged 60 years and older with chronic diseases. A cross-sectional study was conducted on 352 elderly farmers in nine sub-districts of Nong Suea District, Pathum Thani Province, Thailand via convenience sampling. Questionnaires were used as instruments to gather data about demographic and working factors. The risk factors associated with elderly Thai farmers' perceptions of hot conditions on outdoor farms were identified by using binary logistic regression. The most common chronic illnesses were hypertension (35.8%), heart disease (34.4%), and diabetes mellitus (24.5%). More than 60.5% of the participants perceived their hot conditions to be high. The results of binary logistic regression show that low income and work duration ≤8.0 hours per day were risk factors related to perceived hot conditions on outdoor farms (P value < 0.05). These findings may be used by relevant authorities to support elderly farmers by emphasizing the importance of individual and work-related factors. Relevant government agencies should consider formulating working standards in hot conditions specifically for elderly farm workers.","PeriodicalId":17570,"journal":{"name":"Journal of UOEH","volume":"44 3","pages":"229-238"},"PeriodicalIF":0.0,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"33459090","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Effects of Fatty Acids on Proliferation of Cultured Wild-type and FABP5-KO Thymic Epithelial Cells. 脂肪酸对培养野生型和FABP5-KO胸腺上皮细胞增殖的影响。

Journal of UOEH Pub Date : 2022-01-01 DOI: 10.7888/juoeh.44.239

Yasuhiro Adachi

{"title":"Effects of Fatty Acids on Proliferation of Cultured Wild-type and FABP5-KO Thymic Epithelial Cells.","authors":"Yasuhiro Adachi","doi":"10.7888/juoeh.44.239","DOIUrl":"https://doi.org/10.7888/juoeh.44.239","url":null,"abstract":"Lipids including fatty acids (FAs), which are water-insoluble molecules, are not only a cellular energy source but also signaling molecules that induce and modulate the expression of various cellular functions. Fatty acid-binding proteins (FABP) bind FAs in the cytoplasm, and are thought to determine the cellular localization of FAs. In a previous observation, FABP5 was expressed in thymic epithelial cells (TEC) in the thymus and was influenced by FAs. Fatty acids have mostly inhibitory effects on various cell types, including cancer cells, but their effects on TEC have not been well investigated. In this study, we investigated the effects of long-chain FAs (LCFAs) and the involvement of FABP5 in cell proliferation using a serum-free primary culture system. The results showed that saturated fatty acids did not affect proliferation, but n-3 long-chain polyunsaturated FA (LCPUFA) reduced, n-6 LCPUFA increased, and retinoic acid strongly reduced the percentage of proliferating wild-type TEC. The proliferation of FABP5-KO TEC was more significantly affected by LCPUFA, suggesting that FABP5 is an important modulator of FA-mediated TEC proliferation. These observations may provide a basis for exploring the properties of TEC.","PeriodicalId":17570,"journal":{"name":"Journal of UOEH","volume":"44 3","pages":"239-248"},"PeriodicalIF":0.0,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"33459091","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

[A Case of Hearing Loss Preceding Anterior Inferior Cerebellar Artery Infarction Syndrome With a Progressive Course]. 听力丧失伴进行性小脑前下动脉梗死综合征1例。

Journal of UOEH Pub Date : 2022-01-01 DOI: 10.7888/juoeh.44.389

Jumpei Kiyono, Hirotsugu Ohta, Junkoh Yamamoto

引用次数: 0

Hepatic Cyst Infection Following Recurrent Biliary Obstruction in Polycystic Liver Disease. 多囊性肝病复发性胆道梗阻后肝囊肿感染。

Journal of UOEH Pub Date : 2022-01-01 DOI: 10.7888/juoeh.44.353

Koichiro Miyagawa, Yu Nakano, Akitoshi Yoneda, Masashi Kusanaga, Shinji Oe, Yuichi Honma, Michihiko Shibata, Masaru Harada

{"title":"Hepatic Cyst Infection Following Recurrent Biliary Obstruction in Polycystic Liver Disease.","authors":"Koichiro Miyagawa, Yu Nakano, Akitoshi Yoneda, Masashi Kusanaga, Shinji Oe, Yuichi Honma, Michihiko Shibata, Masaru Harada","doi":"10.7888/juoeh.44.353","DOIUrl":"https://doi.org/10.7888/juoeh.44.353","url":null,"abstract":"An 89-year-old man with polycystic liver disease (PCLD) received uncovered self-expandable metallic stent (SEMS) placement above the papilla for malignant biliary obstruction caused by cholangiocarcinoma. He developed cholangitis ten months later due to SEMS occlusion caused by tumor ingrowth, and 2 plastic biliary stents were placed inside the SEMS across the papilla. Fever and right costal pain appeared two weeks after reintervention. Suspecting hepatic cyst infection based on imaging studies, percutaneous transhepatic cyst drainage was performed. Increased inflammatory cells and the presence of pathogens in the cyst fluid led to a definitive diagnosis of hepatic cyst infection. Following drainage, the hepatic cyst shrank with resolution of the symptoms. SEMS occlusive-related cholangitis or retrograde infection due to duodenal-biliary reflux after reintervention was considered as the cause of the hepatic cyst infection. Careful clinical and imaging evaluation should be performed in patients with PCLD undergone biliary stenting, because cyst infection may occur following stent occlusion or subsequent biliary reintervention.","PeriodicalId":17570,"journal":{"name":"Journal of UOEH","volume":"44 4","pages":"353-358"},"PeriodicalIF":0.0,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10841260","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

[Implementation of Clinical Practice in Adult Nursing (Chronic Care) During the COVID-19 Pandemic: Report on the Development and Implementation of a Training Program for Clinical Shadowing]. [COVID-19大流行期间成人护理(慢性护理)临床实践的实施:临床实习培训计划的制定和实施报告]。

Journal of UOEH Pub Date : 2022-01-01 DOI: 10.7888/juoeh.44.313

Tomoko Hagiwara, Kyohei Yamaguchi

{"title":"[Implementation of Clinical Practice in Adult Nursing (Chronic Care) During the COVID-19 Pandemic: Report on the Development and Implementation of a Training Program for Clinical Shadowing].","authors":"Tomoko Hagiwara, Kyohei Yamaguchi","doi":"10.7888/juoeh.44.313","DOIUrl":"https://doi.org/10.7888/juoeh.44.313","url":null,"abstract":"Before the outbreak of COVID-19, \"Clinical Practice in Adult Nursing (Chronic Care)\", a professional course to acquire basic nursing practice skills for the care of adult patients with chronic diseases, was conducted on site in the wards of internal medicine, outpatient departments, and the admissions support office for a total of three weeks. Due to the spread of the COVID-19 epidemic, however, clinical practice was carried out online from May 2020, and was resumed on site at our university hospital in October 2020. A restriction was placed on the length of time spent at the hospital for on-site training, referring to the training standards based on our university's new coronavirus response manual, and a training program was developed for hospital ward training, consisting mainly of shadowing practice performed without speaking or coming into contact with patients. In principle, two students were assigned to one patient: one in the morning and the other in the afternoon. In addition, for practicing the acquisition of patient information through conversation and the provision of nursing assistance, the perspectives used in the process of shadowing were clearly defined so that students could maintain active attitudes in clinical practice, and support was provided so that students could have the experience of engaging with patients, using nurses as mediators. In the results, the students evaluated the contents of the prepared assistance based on their own nursing plan in reference to the practice of the nurse as a mediator, and compared that with the assistance practiced by the nurse based on clinical judgment, which contributed to acquiring practical learning supported by the grounds for clinical judgment. However, the students could not experience the process of building supportive relationships and the implementation of nursing skills, which remained an issue.","PeriodicalId":17570,"journal":{"name":"Journal of UOEH","volume":"44 3","pages":"313-319"},"PeriodicalIF":0.0,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"33458573","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0