Maria Lizarazo Jimenez MD , Ana Cristina Montenegro MD, MSc, FACP , Natalia Morales MD , Andres Jimenez Echandia MD
{"title":"Early Discharge Protocol for Patients With Uncomplicated Deep Vein Thrombosis: Cohort Characterization and Incidence of Major Bleeding, Minor Bleeding, and Recurrence","authors":"Maria Lizarazo Jimenez MD , Ana Cristina Montenegro MD, MSc, FACP , Natalia Morales MD , Andres Jimenez Echandia MD","doi":"10.1016/j.jvsv.2024.102070","DOIUrl":"10.1016/j.jvsv.2024.102070","url":null,"abstract":"","PeriodicalId":17537,"journal":{"name":"Journal of vascular surgery. Venous and lymphatic disorders","volume":"13 2","pages":"Article 102070"},"PeriodicalIF":2.8,"publicationDate":"2025-02-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143394918","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Oscar Moreno MD , Nathaniel Parchment MD , Sabrina Rocco MS , Kate Micallef BS , Kiran Kumar BS , Catherine Luke LVT , Amber Clay RVT, RDCS , Qing Cai MS , Daniel Myers DVM, MPH , David Gordon MD , Thomas Wakefield MD , Peter Henke MD , Andrea Obi MD
{"title":"In Vitro Vascular Permeability Modulation in Venous Endothelium With Sirolimus","authors":"Oscar Moreno MD , Nathaniel Parchment MD , Sabrina Rocco MS , Kate Micallef BS , Kiran Kumar BS , Catherine Luke LVT , Amber Clay RVT, RDCS , Qing Cai MS , Daniel Myers DVM, MPH , David Gordon MD , Thomas Wakefield MD , Peter Henke MD , Andrea Obi MD","doi":"10.1016/j.jvsv.2024.102092","DOIUrl":"10.1016/j.jvsv.2024.102092","url":null,"abstract":"","PeriodicalId":17537,"journal":{"name":"Journal of vascular surgery. Venous and lymphatic disorders","volume":"13 2","pages":"Article 102092"},"PeriodicalIF":2.8,"publicationDate":"2025-02-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143395501","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Slade Smith, Hayden Butts, Jack Owens, Sara Matheson, Mary Meghan Dickerson, Arjun Jayaraj
{"title":"Outcomes following stenting for symptomatic chronic iliofemoral venous stenosis - A comparison of three stent types.","authors":"Slade Smith, Hayden Butts, Jack Owens, Sara Matheson, Mary Meghan Dickerson, Arjun Jayaraj","doi":"10.1016/j.jvsv.2025.102208","DOIUrl":"https://doi.org/10.1016/j.jvsv.2025.102208","url":null,"abstract":"<p><strong>Objective: </strong>Venous stenting has become the standard of care for patients with iliofemoral venous stenosis who have failed conservative therapy. While outcome data following such stenting exist for Wallstents and Wallstent - Z stent combination, such data for dedicated stents is sparse outside of industry-sponsored trials. This study aims to address this gap by comparing the outcomes of matched cohorts of limbs that underwent stenting with either the Medtronic Abre stent (Medtronic Inc, Minneapolis, MN), the Bard Venovo stent (Becton, Dickinson, and Co, Franklin Lakes, NJ), or Wallstent-Zenith (Z) stent combination (Boston Scientific, Marlborough, MA; Cook Medical Inc, Bloomington, IN).</p><p><strong>Methods: </strong>Contemporaneously entered data on matched cohorts of patients who underwent stenting from 2016 to 2022 for quality of life (QOL)-impairing iliofemoral venous stenosis (not occlusion) after failing conservative therapy was analyzed. The venous clinical severity score (VCSS: 0-27), grade of swelling (GOS: 0-4), visual analog scale pain score (VAS pain score: 0-10), and CIVIQ-20 quality of life (QOL) score were evaluated initially and post stenting to assess the effects of stenting. ANOVA and paired t-tests were used to compare clinical and QOL variables, while Kaplan-Meier analysis was used to examine primary, primary-assisted, and secondary stent patencies with log-rank test used to discriminate between different curves.</p><p><strong>Results: </strong>There was a total of 198 limbs that had undergone stenting including 68 in the Abre, 60 in the Venovo and 70 in the Wallstent - Z stent groups. The median age for the entire cohort was 65 years (range 21-101 years). The cohort included 141 women and 57 men. Left laterality (112 limbs) was more common than right laterality (86 limbs). Post-thrombotic syndrome was seen in 146 limbs and nonthrombotic iliac vein lesions/May-Thurner syndrome in 52 limbs. The median BMI was 35. Median follow up was 20 months. For the entire cohort, post stenting, VCSS improved from 6 to 4.5 at 3 months (p<0.0001) further improved to 4 at 6 months (p<0.0001) and remained at 4 at 12 months (p<0.0001), and 24 months (p<0.0001). GOS for the entire cohort improved from 3 to 1 at 3 months (p<0.0001) and remained at 1 at 6 months, (p<0.0001), 12 months (p<0.0001), and 24 months (p<0.0001). VAS pain score for the entire cohort improved from 8 to 2 at 3 months (p<0.0001), increased to 3 at 6 months (p<0.0001) before dropping to 2 at 12 months (p<0.0001), and remained at 2 at 24 months (p<0.0001). The CIVIQ-20 score for the entire cohort improved from 61 to 38 (p<0.0001) over the duration of follow up. The primary patencies for the Abre, Bard, and Wallstent-Z stent groups at 32 months were 93%, 86%, and 92%, respectively (p=0.37). Primary assisted patencies for all 3 groups at 32 months was 100% (p=0.08). There were no stent occlusions in any of the groups. Reintervention was pursued for QOL impairin","PeriodicalId":17537,"journal":{"name":"Journal of vascular surgery. Venous and lymphatic disorders","volume":" ","pages":"102208"},"PeriodicalIF":2.8,"publicationDate":"2025-02-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143374438","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Successful Endovascular Treatment of Post-traumatic Iliac Arteriovenous Fistula.","authors":"Leizhi Ku, Di Huang, Ming Qi","doi":"10.1016/j.jvsv.2025.102207","DOIUrl":"https://doi.org/10.1016/j.jvsv.2025.102207","url":null,"abstract":"","PeriodicalId":17537,"journal":{"name":"Journal of vascular surgery. Venous and lymphatic disorders","volume":" ","pages":"102207"},"PeriodicalIF":2.8,"publicationDate":"2025-02-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143374440","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Colin M Cleary, Emily Orosco, James Gallagher, James Gallagher, Mouhanad Ayach, Kaveh Davoudi, Allison Bailey, Parth Shah, Elizabeth Aitcheson, Ya-Huei Li, Kristy Wrana, Edward D Gifford
{"title":"Continuation of Anticoagulation through Ambulatory Phlebectomy Does Not Impact Post-Operative Bleeding Risk.","authors":"Colin M Cleary, Emily Orosco, James Gallagher, James Gallagher, Mouhanad Ayach, Kaveh Davoudi, Allison Bailey, Parth Shah, Elizabeth Aitcheson, Ya-Huei Li, Kristy Wrana, Edward D Gifford","doi":"10.1016/j.jvsv.2025.102199","DOIUrl":"https://doi.org/10.1016/j.jvsv.2025.102199","url":null,"abstract":"<p><strong>Objectives: </strong>Chronic anticoagulation for atrial fibrillation, history of venous thromboembolism, and following heart valve replacement is often stopped or bridged for surgery. Our institutional practice is to continue anticoagulation through ambulatory phlebectomy (AP) procedures. As such, we aimed to compare post-procedure bleeding and major adverse events in patients on anticoagulation who received ambulatory phlebectomy compared to patients not on anticoagulation.</p><p><strong>Methods: </strong>We included all patients who required AP from January 2016 to February 2023. Given the low frequency of chronic anticoagulation during the study period, as defined as patients on anticoagulation ≥30 days before index procedure and not held through the procedure, a propensity score match of 16 demographic parameters was performed to better match patients. Following propensity matching, we compared the frequency and quality of post-procedural bleeding (none, incisional, large volume), extent of post-procedural ecchymosis (none, minimal, moderate, significant), and pain (minimal, moderate, severe) on follow up examination with a provider. Thirty-day ED visits and major adverse cardiac events (MACE) were also recorded for each patient. Continuous variables were compared using independent t-tests or Mann-Whitney U tests while categorical variables were compared using a Chi-square or Fisher's Exact test.</p><p><strong>Results: </strong>In total, 1,853 patients received AP from four outpatient offices during the study period, 101 (5.5%) of which were on chronic anticoagulation. Seventy patients for each group were propensity score matched in key demographics including age, gender, BMI, Clinical-Etiology-Anatomy-Pathophysiology (CEAP) classification, prior vein procedures, concomitant laser procedures, number of phlebectomies performed, and co-morbidities like history of deep vein thrombosis, pulmonary embolism, and peripheral arterial disease. There were no intra-operative major bleeding events. Patients on chronic anticoagulation were not more likely to have increased post-procedural bleeding (2.9% vs 0%, p=0.496), significant ecchymosis (4.5% vs 1.5%, p=0.671), severe pain on follow up (1.4% vs 0%, p=0.604), or increased likelihood of post-procedural cellulitis (1.4% vs 0%, p=1.000). There were no instances of 30-day ED visits, or MACE. Within patients on anticoagulation, use of rivaroxaban (8%) had higher incidence of bleeding than those on apixaban or warfarin (0%), however, these findings were not significant.</p><p><strong>Conclusions: </strong>Ambulatory phlebectomy while continuing chronic anticoagulation did not result in an increased rate of bleeding, ED visits, or major adverse events. It is likely safe to continue anticoagulation throughout these outpatient procedures.</p>","PeriodicalId":17537,"journal":{"name":"Journal of vascular surgery. Venous and lymphatic disorders","volume":" ","pages":"102199"},"PeriodicalIF":2.8,"publicationDate":"2025-01-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143074942","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}