Journal of vascular surgery. Venous and lymphatic disorders最新文献

{"title":"Effectiveness and safety of sirolimus in the treatment of venous malformations: A meta-analysis of prospective studies","authors":"Guoyong Wang MD,&nbsp;Wei Lu MD,&nbsp;Yingjie Zhu MD,&nbsp;Chaonan Wang MD, PhD,&nbsp;Xiaonan Yang MD, PhD","doi":"10.1016/j.jvsv.2025.102284","DOIUrl":"10.1016/j.jvsv.2025.102284","url":null,"abstract":"<div><h3>Background</h3><div>Venous malformations are prevalent vascular anomalies. Recent clinical studies have explored the use of sirolimus for these conditions, particularly in patients who are not candidates for, or have shown limited response to, traditional treatments such as sclerotherapy and surgery. This meta-analysis systematically evaluates the efficacy and safety of sirolimus in treating venous malformations.</div></div><div><h3>Methods</h3><div>We conducted searches in PubMed, Cochrane Library, Web of Science, and the Cochrane Database of Systematic Reviews until August 10, 2024. The quality of the included prospective studies (including both randomized and single-arm pre-post trials) was assessed using the Cochrane risk of bias tool. Statistical analyses were performed with Review Manager (Version 5.4).</div></div><div><h3>Results</h3><div>Our analysis included eight prospective studies involving 74 patients. Primary outcomes measured changes in the volume and size of the malformations. Secondary outcomes assessed were functional disability scores, hemoglobin levels, coagulation indices, transfusion requirements, patient quality of life, and radiologic responses. Sirolimus demonstrated significant therapeutic benefits, with an odds ratio of 0.02 (95% confidence interval, 0.00-0.08) across six studies evaluating dichotomous variables. Results for continuous variables were consistent. Sirolimus showed safety in short-to medium-term use, with reversible mild to moderate side effects such as oral ulcers and liver function abnormalities. No severe adverse events (grade 3-5) were reported.</div></div><div><h3>Conclusions</h3><div>Sirolimus is effective and safe for treating venous malformations, especially in patients unresponsive to conventional therapies. Future studies should explore long-term effects, optimal dosages, and administration techniques.</div></div>","PeriodicalId":17537,"journal":{"name":"Journal of vascular surgery. Venous and lymphatic disorders","volume":"13 6","pages":"Article 102284"},"PeriodicalIF":2.8,"publicationDate":"2025-07-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144575781","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Predictors of inferior vena cava filter retrieval in a population-based Canadian cohort","authors":"Serena Ip BSc, BHSc ,&nbsp;Konrad Salata MD, PhD ,&nbsp;Jin Luo MSc ,&nbsp;Charles de Mestral MDCM, PhD ,&nbsp;Graham Roche-Nagle MD, MBA","doi":"10.1016/j.jvsv.2025.102283","DOIUrl":"10.1016/j.jvsv.2025.102283","url":null,"abstract":"<div><h3>Background</h3><div>The objective of this study was to determine the predictors of inferior vena cava (IVC) filter retrieval in a contemporary North American cohort of patients who received an IVC filter.</div></div><div><h3>Methods</h3><div>A retrospective population-based cohort study was conducted using Ontario administrative health data. Physician service fee codes were used to identify all adults with an IVC filter placement from January 1, 2010, to December 31, 2019. The cumulative incidence of filter retrieval over time was calculated, accounting for death as a competing risk. Multivariable sub-distribution hazard regression models were constructed to quantify the association between covariates and the likelihood of filter retrieval.</div></div><div><h3>Results</h3><div>A total of 5617 people received an IVC filter during the study period. Median follow-up was 1.8 years (interquartile range, 0.2-5.4 years). The probability of filter retrieval plateaued under 40% with most retrievals (96%; n = 2049 of 2135) occurring within 1 year of placement. Filter placement in a teaching hospital (hazard ratio, 1.85; 95% confidence interval, 1.60-2.02), and placement after 2016 were associated with a greater likelihood of filter retrieval. Older age and greater comorbidity were associated with a lower likelihood of filter retrieval.</div></div><div><h3>Conclusions</h3><div>In this population-based study of IVC filter retrieval, less than 40% of filters were retrieved, mostly within 1 year of insertion. Better coordination and standardization of services responsible for follow-up of patients with IVC filters are needed.</div></div>","PeriodicalId":17537,"journal":{"name":"Journal of vascular surgery. Venous and lymphatic disorders","volume":"13 6","pages":"Article 102283"},"PeriodicalIF":2.8,"publicationDate":"2025-06-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144528581","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Comparison of clinical outcomes among patients with proximal versus isolated distal deep vein thrombosis: A systematic review and meta-analysis","authors":"Siyi Zhang BS,&nbsp;Can Shi PhD,&nbsp;Xia Wang MS,&nbsp;Huilin Xu BS,&nbsp;Ziwei Liu BS,&nbsp;Songhua Chen BS,&nbsp;Tian Wu PhD,&nbsp;Ren Guo PhD","doi":"10.1016/j.jvsv.2025.102281","DOIUrl":"10.1016/j.jvsv.2025.102281","url":null,"abstract":"<div><h3>Objective</h3><div>Deep vein thrombosis (DVT) ranks among the top five most prevalent vascular diseases globally and encompasses proximal deep vein thrombosis (PDVT) and isolated distal deep vein thrombosis (IDDVT). IDDVT affects approximately 50% to 65% of patients with DVT. However, due to a lack of prospective studies and conflicting perspectives on its potential to lead to pulmonary embolism (PE), the management of IDDVT remains contentious. Therefore, this meta-analysis was conducted to compare the clinical outcomes of PDVT and IDDVT.</div></div><div><h3>Method</h3><div>We searched studies including proximal and isolated distal thrombotic outcomes in the electronic databases PubMed, EMBASE, Cochrane, and Web of Science. The literature was then screened based on title, abstract, and full text to exclude those that did not meet the criteria. A total of 21 cohort and randomized controlled studies were included.</div></div><div><h3>Results</h3><div>Compared with IDDVT, PDVT was associated with higher rates in recurrent vein thromboembolism (VTE) (odds ratio [OR], 1.62; 95% confidence interval [CI], 1.35-1.93; <em>P</em> &lt; .001), PE (OR, 1.52; 95% CI, 1.16-1.99; <em>P</em> = .002), major bleeding (OR, 1.95; 95% CI, 1.23-3.09; <em>P</em> = .005), and all-cause mortality (OR, 2.02; 95% CI, 1.19-3.44; <em>P</em> = .009). However, no significant differences were found in the rates of any bleeding (OR, 1.57; 95% CI, 0.96-2.58; <em>P</em> = .070) and nonmajor bleeding (OR, 1.03; 95% CI, 0.69-1.54; <em>P</em> = .88).</div></div><div><h3>Conclusions</h3><div>Compared with patients with PDVT, patients with IDDVT may have lower rates of recurrent VTE, PE, major bleeding events, and all-cause mortality, demonstrating safer clinical outcomes.</div></div>","PeriodicalId":17537,"journal":{"name":"Journal of vascular surgery. Venous and lymphatic disorders","volume":"13 6","pages":"Article 102281"},"PeriodicalIF":2.8,"publicationDate":"2025-06-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144368939","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Frequency of left common iliac vein compression in asymptomatic adolescents and young adults","authors":"Kevin Wang MD ,&nbsp;Luie Siegel BA ,&nbsp;Alexis Betancourt MD ,&nbsp;Nicole A. Keefe MD ,&nbsp;Gloria Salazar MD ,&nbsp;Sydney Browder BS ,&nbsp;William A. Marston MD","doi":"10.1016/j.jvsv.2025.102282","DOIUrl":"10.1016/j.jvsv.2025.102282","url":null,"abstract":"<div><h3>Objective</h3><div>Venous compression at the iliac confluence is a reported risk factor for deep vein thrombosis, with venous stenting as the standard management for relieving this compression. Kibbe et al demonstrated that left common iliac vein (LCIV) compression is present in 35.3% of asymptomatic patients. However, this study included only adults with an average age of 40 years. The iliac vein confluence in patients under 21 years with no symptoms attributable to venous disease was evaluated in this study. The study goal is to determine prevalence of LCIV narrowing in patients under age 21 years, and as such, assist in determining the appropriate treatment for iliac vein compression in this patient population.</div></div><div><h3>Methods</h3><div>A retrospective review of patients aged 13-20 undergoing abdominal/pelvic computed tomography (CT) imaging for nonvascular indications was performed. This group was compared with patients aged 35 to 65 years undergoing CT imaging for similar reasons. Axial CT images were reviewed by two independent examiners to identify the diameter of the noncompressed left and right CIVs below the confluence and the diameter of the LCIV at the site of compression between the right common iliac artery and spine.</div></div><div><h3>Results</h3><div>A total of 122 patients aged 13 to 20 years were identified with high-quality CT imaging and no venous symptoms for image review. Mean LCIV diameter was 12.7 ± 2.5 mm, and mean right CIV diameter was 13.1 ± 2.2 mm. The diameter of the LCIV at the confluence was 4.2 ± 1.8 mm, resulting in a mean diameter stenosis of the LCIV of 69.4% ± 12.6%. In this population, 55.7% of patients were found to have ≥70% stenosis of the LCIV on CT imaging compared with 1.7% of patients aged 35 to 65 years (<em>P</em> &lt; .001). There was no statistical difference in the percentage of LCIV stenosis in young patients based on body mass index, gender, race, or ethnicity.</div></div><div><h3>Conclusions</h3><div>Severe compression of the LCIV at the iliac confluence was identified in over 50% of asymptomatic patients aged 13 to 20 years on CT imaging performed for nonvascular reasons. This suggests that narrowing of the LCIV is a normal anatomic finding in this age group. The incidence of severe compression is significantly lower in older asymptomatic persons. In young persons, the high incidence of iliac vein compression on CT imaging suggests that this finding may not be a significant risk factor for deep vein thrombosis or limb symptoms, questioning the need for routine intervention for compression correction in this patient population.</div></div>","PeriodicalId":17537,"journal":{"name":"Journal of vascular surgery. Venous and lymphatic disorders","volume":"13 6","pages":"Article 102282"},"PeriodicalIF":2.8,"publicationDate":"2025-06-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144368940","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Venous bypass using the internal jugular vein as the outflow tract for treating central venous stenosis and cephalic arch stenosis in hemodialysis access","authors":"Mo Wang MD ,&nbsp;Peng Lu MD ,&nbsp;Quanming Li MD ,&nbsp;Chang Shu MD ,&nbsp;Yang Zhou MD ,&nbsp;Tun Wang MD","doi":"10.1016/j.jvsv.2025.102280","DOIUrl":"10.1016/j.jvsv.2025.102280","url":null,"abstract":"<div><h3>Objective</h3><div>Central venous stenosis (CVS) and cephalic arch stenosis (CAS) remain significant issues in the long-term management of hemodialysis access. Surgical bypass serves as a crucial option for symptom relief and access preservation when endovascular treatments fail. This study aimed to evaluate the effectiveness and safety of using the internal jugular vein (IJV) as the outflow tract in bypass surgery for CVS and CAS.</div></div><div><h3>Methods</h3><div>From December 2021 to September 2024, 21 patients undergoing hemodialysis who developed CVS (n = 15) or CAS (n = 6), were undertaken. Extra-anatomic venous bypass using the IJV were performed. Before surgical bypass, all patients had computed tomography angiography (CTA) and bilateral venograms of the upper central venous system. Color Doppler ultrasound was used to measure flow volume. A literature review was conducted to analyze the outcomes of previous studies that using venous bypass for the treatment of CVS in patients with upper extremity hemodialysis access.</div></div><div><h3>Results</h3><div>Technical success was achieved in all cases. Fifteen cases presented with CVS (11 men and 4 women, with a mean age of 56 ± 11 years [range, 37-82 years]) were treated by six surgical approaches include cephalic vein to contralateral-IJV bypass (n = 3), axillary vein to contralateral-IJV bypass (n = 5), external jugular vein to contralateral-IJV bypass (n = 2), IJV to contralateral-IJV bypass (n = 2), axillary vein to ipsilateral-IJV bypass (n = 1), cephalic vein to ipsilateral-IJV bypass (n = 1), and arteriovenous graft to ipsilateral-IJV bypass (n = 1). The median follow-up was 22 months (interquartile range, 12-24 months). The primary patency rate and secondary patency were 79% and 79% at 1 year and 65% and 79% at 2 years. Six patients presented with CAS (2 men and 4 women, with a mean age of 51 ± 9 years [range, 38 to 59 years]) and were treated by cephalic vein to ipsilateral-IJV bypass (n = 6). The median follow-up was 22 months (interquartile range, 15-26 months). The primary patency rate and secondary patency were 100% and 100% at 1 year and 60% and 60% at 2 years. All patients showed significant symptom improvement postoperation, with no perioperative mortality.</div></div><div><h3>Conclusions</h3><div>Extra-anatomic venous bypass using the IJV as outflow tract is an effective and safe alternative, providing good graft patency and low postoperative complications during midterm follow-up. Careful selection of inflow and outflow tracts is crucial for optimal outcomes.</div></div>","PeriodicalId":17537,"journal":{"name":"Journal of vascular surgery. Venous and lymphatic disorders","volume":"13 6","pages":"Article 102280"},"PeriodicalIF":2.8,"publicationDate":"2025-06-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144484835","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Rationale for glue embolization rather than foam sclerosis in the endovascular treatment of pelvic reservoir in pelvic venous disorders","authors":"Romaric Loffroy MD, PhD","doi":"10.1016/j.jvsv.2025.102216","DOIUrl":"10.1016/j.jvsv.2025.102216","url":null,"abstract":"","PeriodicalId":17537,"journal":{"name":"Journal of vascular surgery. Venous and lymphatic disorders","volume":"13 4","pages":"Article 102216"},"PeriodicalIF":2.8,"publicationDate":"2025-06-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144270685","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Natural course of portal vein aneurysm - does morphology matter?","authors":"Admir Kurtcehajic PhD,&nbsp;Enver Zerem MD,&nbsp;Suad Kunosic PhD,&nbsp;Ervin Alibegovic MD,&nbsp;Predrag Jovanovic MD,&nbsp;Ahmed Hujdurovic PhD","doi":"10.1016/j.jvsv.2025.102231","DOIUrl":"10.1016/j.jvsv.2025.102231","url":null,"abstract":"","PeriodicalId":17537,"journal":{"name":"Journal of vascular surgery. Venous and lymphatic disorders","volume":"13 4","pages":"Article 102231"},"PeriodicalIF":2.8,"publicationDate":"2025-06-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144270686","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Events of Interest","authors":"","doi":"10.1016/S2213-333X(25)00102-7","DOIUrl":"10.1016/S2213-333X(25)00102-7","url":null,"abstract":"","PeriodicalId":17537,"journal":{"name":"Journal of vascular surgery. Venous and lymphatic disorders","volume":"13 4","pages":"Article 102267"},"PeriodicalIF":2.8,"publicationDate":"2025-06-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144271561","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Information for Readers","authors":"","doi":"10.1016/S2213-333X(25)00101-5","DOIUrl":"10.1016/S2213-333X(25)00101-5","url":null,"abstract":"","PeriodicalId":17537,"journal":{"name":"Journal of vascular surgery. Venous and lymphatic disorders","volume":"13 4","pages":"Article 102266"},"PeriodicalIF":2.8,"publicationDate":"2025-06-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144271560","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Commentary on compression after radiofrequency ablation: Limitations and research gaps","authors":"Yang Xiao PhD,&nbsp;Shi Hongshuo PhD,&nbsp;Liu Guobin PhD","doi":"10.1016/j.jvsv.2025.102218","DOIUrl":"10.1016/j.jvsv.2025.102218","url":null,"abstract":"","PeriodicalId":17537,"journal":{"name":"Journal of vascular surgery. Venous and lymphatic disorders","volume":"13 4","pages":"Article 102218"},"PeriodicalIF":2.8,"publicationDate":"2025-06-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144270720","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}