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Journal of Thoracic Oncology最新文献

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PP01.06 Aurora Kinase A Inhibition Potentiates KRASG12C Inhibition and Overcomes Resistance to Sotorasib in Lung Cancer
IF 21 1区 医学
Journal of Thoracic Oncology Pub Date : 2025-04-01 DOI: 10.1016/j.jtho.2025.03.014
Jong Woo Lee, Jackie Shi, Julian Barrantes, Sundong Kim, Sebastian Cruz-Gomez, Cindy Yang, Barbara Burtness
{"title":"PP01.06 Aurora Kinase A Inhibition Potentiates KRASG12C Inhibition and Overcomes Resistance to Sotorasib in Lung Cancer","authors":"Jong Woo Lee, Jackie Shi, Julian Barrantes, Sundong Kim, Sebastian Cruz-Gomez, Cindy Yang, Barbara Burtness","doi":"10.1016/j.jtho.2025.03.014","DOIUrl":"10.1016/j.jtho.2025.03.014","url":null,"abstract":"","PeriodicalId":17515,"journal":{"name":"Journal of Thoracic Oncology","volume":"20 4","pages":"Page S5"},"PeriodicalIF":21.0,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143758989","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
OA05.01 Deep Mutational Scanning Reveals Novel EGFR Mutations Conferring Resistance to Osimertinib and BLU-945
IF 21 1区 医学
Journal of Thoracic Oncology Pub Date : 2025-04-01 DOI: 10.1016/j.jtho.2025.03.007
Dylan Yueyang Wang , Michela Ranieri , Fiona Sherman , Jiehui Deng , Kwok-Kin Wong , Elaine Shum , John T. Poirier
{"title":"OA05.01 Deep Mutational Scanning Reveals Novel EGFR Mutations Conferring Resistance to Osimertinib and BLU-945","authors":"Dylan Yueyang Wang , Michela Ranieri , Fiona Sherman , Jiehui Deng , Kwok-Kin Wong , Elaine Shum , John T. Poirier","doi":"10.1016/j.jtho.2025.03.007","DOIUrl":"10.1016/j.jtho.2025.03.007","url":null,"abstract":"","PeriodicalId":17515,"journal":{"name":"Journal of Thoracic Oncology","volume":"20 4","pages":"Page S2"},"PeriodicalIF":21.0,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143759286","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
PP01.14 Paired Sample Analyses of NSCLC After SCLC Transformation
IF 21 1区 医学
Journal of Thoracic Oncology Pub Date : 2025-04-01 DOI: 10.1016/j.jtho.2025.03.021
Brinda Gupta , Kieran Sweeney , Andrew Elliott , Jennifer Marks , Ari Vanderwalde , Sonam Puri , Misty D. Shields , Jorge J. Nieva , Heloisa P. Soares , Patrick C. Ma , Balazs Halmos , Stephen V. Liu
{"title":"PP01.14 Paired Sample Analyses of NSCLC After SCLC Transformation","authors":"Brinda Gupta , Kieran Sweeney , Andrew Elliott , Jennifer Marks , Ari Vanderwalde , Sonam Puri , Misty D. Shields , Jorge J. Nieva , Heloisa P. Soares , Patrick C. Ma , Balazs Halmos , Stephen V. Liu","doi":"10.1016/j.jtho.2025.03.021","DOIUrl":"10.1016/j.jtho.2025.03.021","url":null,"abstract":"","PeriodicalId":17515,"journal":{"name":"Journal of Thoracic Oncology","volume":"20 4","pages":"Page S8"},"PeriodicalIF":21.0,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143759395","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
PP01.04 Targeting the Minimal Residual Disease to Increase the Targeted Therapy Depth of Response in EGFR-Driven Lung Cancer
IF 21 1区 医学
Journal of Thoracic Oncology Pub Date : 2025-04-01 DOI: 10.1016/j.jtho.2025.03.012
David Bracquemond , Maicol Mancini , Antonio Maraver
{"title":"PP01.04 Targeting the Minimal Residual Disease to Increase the Targeted Therapy Depth of Response in EGFR-Driven Lung Cancer","authors":"David Bracquemond , Maicol Mancini , Antonio Maraver","doi":"10.1016/j.jtho.2025.03.012","DOIUrl":"10.1016/j.jtho.2025.03.012","url":null,"abstract":"","PeriodicalId":17515,"journal":{"name":"Journal of Thoracic Oncology","volume":"20 4","pages":"Page S4"},"PeriodicalIF":21.0,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143759490","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
PP01.26 Investigating for Blood Circulating N-Linked Glycoproteins Associated With Immunotherapy Response in Pleural Mesothelioma
IF 21 1区 医学
Journal of Thoracic Oncology Pub Date : 2025-04-01 DOI: 10.1016/j.jtho.2025.03.029
Pierre Marchal , Joel Spies , Sophie Braga Lagache , Lydie Lane , Manfred Heller , Ferdinando Cerciello
{"title":"PP01.26 Investigating for Blood Circulating N-Linked Glycoproteins Associated With Immunotherapy Response in Pleural Mesothelioma","authors":"Pierre Marchal , Joel Spies , Sophie Braga Lagache , Lydie Lane , Manfred Heller , Ferdinando Cerciello","doi":"10.1016/j.jtho.2025.03.029","DOIUrl":"10.1016/j.jtho.2025.03.029","url":null,"abstract":"","PeriodicalId":17515,"journal":{"name":"Journal of Thoracic Oncology","volume":"20 4","pages":"Page S11"},"PeriodicalIF":21.0,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143758990","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
OA02.01 Selective Translation of PBK (PDZ-Binding Kinase) is a Novel Mechanism of Drug Tolerance to Targeted Therapies in EGFR-Mutant Lung Cancer
IF 21 1区 医学
Journal of Thoracic Oncology Pub Date : 2025-04-01 DOI: 10.1016/j.jtho.2025.03.005
Camille Léonce , Anne-Laure Desage , Nour El-Houda Mourksi , Geneviève De Souza , Béatrice Vanbervliet , Camille Charrondière , Constance Nicq , Aurélie Swalduz , Gabriel Ichim , Jean-Jacques Diaz , Christine Lovly , Julien Mazières , Mayeul Tabutin , Maurice Pérol , Sylvie Lantuejoul , Olivier Calvayrac , Fabien Forest , Virginie Marcel , Pierre Saintigny , Sandra Ortiz- Cuaran
{"title":"OA02.01 Selective Translation of PBK (PDZ-Binding Kinase) is a Novel Mechanism of Drug Tolerance to Targeted Therapies in EGFR-Mutant Lung Cancer","authors":"Camille Léonce , Anne-Laure Desage , Nour El-Houda Mourksi , Geneviève De Souza , Béatrice Vanbervliet , Camille Charrondière , Constance Nicq , Aurélie Swalduz , Gabriel Ichim , Jean-Jacques Diaz , Christine Lovly , Julien Mazières , Mayeul Tabutin , Maurice Pérol , Sylvie Lantuejoul , Olivier Calvayrac , Fabien Forest , Virginie Marcel , Pierre Saintigny , Sandra Ortiz- Cuaran","doi":"10.1016/j.jtho.2025.03.005","DOIUrl":"10.1016/j.jtho.2025.03.005","url":null,"abstract":"","PeriodicalId":17515,"journal":{"name":"Journal of Thoracic Oncology","volume":"20 4","pages":"Page S1"},"PeriodicalIF":21.0,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143759284","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
PP01.01 Oncogenic Signaling is Rewired to Support Nucleotide Metabolism in Acquired Resistance to Targeted Therapies in NSCLC
IF 21 1区 医学
Journal of Thoracic Oncology Pub Date : 2025-04-01 DOI: 10.1016/j.jtho.2025.03.009
Jaime L. Schneider , Yutong Dai , Ishita Dhiman , Jingpeng Chen , Shakchhi Joshi , Kiran Kurmi , Morgan Payne , Brandon Gassaway , Steven Gygi , Jessica J. Lin , Aaron Hata , Marcia Haigis
{"title":"PP01.01 Oncogenic Signaling is Rewired to Support Nucleotide Metabolism in Acquired Resistance to Targeted Therapies in NSCLC","authors":"Jaime L. Schneider , Yutong Dai , Ishita Dhiman , Jingpeng Chen , Shakchhi Joshi , Kiran Kurmi , Morgan Payne , Brandon Gassaway , Steven Gygi , Jessica J. Lin , Aaron Hata , Marcia Haigis","doi":"10.1016/j.jtho.2025.03.009","DOIUrl":"10.1016/j.jtho.2025.03.009","url":null,"abstract":"","PeriodicalId":17515,"journal":{"name":"Journal of Thoracic Oncology","volume":"20 4","pages":"Page S3"},"PeriodicalIF":21.0,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143759342","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
PP01.16 Ixazomib Overcomes Platinum Resistance and Induces Autophagy-Mediated Cell Death in Lung Adenocarcinoma
IF 21 1区 医学
Journal of Thoracic Oncology Pub Date : 2025-04-01 DOI: 10.1016/j.jtho.2025.03.023
Muthamil Iniyan Appadurai , Zahraa Wajih Alsafwani , Sanjib Chaudhary , Ashu Shah , Pranay Somavarapu , Sriman N. Dooshety , Ben S. Kubicek , Surinder K. Batra , Imayavaramban Lakshmanan , Apar Kishor Ganti
{"title":"PP01.16 Ixazomib Overcomes Platinum Resistance and Induces Autophagy-Mediated Cell Death in Lung Adenocarcinoma","authors":"Muthamil Iniyan Appadurai , Zahraa Wajih Alsafwani , Sanjib Chaudhary , Ashu Shah , Pranay Somavarapu , Sriman N. Dooshety , Ben S. Kubicek , Surinder K. Batra , Imayavaramban Lakshmanan , Apar Kishor Ganti","doi":"10.1016/j.jtho.2025.03.023","DOIUrl":"10.1016/j.jtho.2025.03.023","url":null,"abstract":"","PeriodicalId":17515,"journal":{"name":"Journal of Thoracic Oncology","volume":"20 4","pages":"Page S9"},"PeriodicalIF":21.0,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143759455","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
PP01.13 Temporal Immune Evolution in a Murine EML4-ALK NSCLC Model: Genomic, Proteomic, and Drug Co-Culture Characterization
IF 21 1区 医学
Journal of Thoracic Oncology Pub Date : 2025-04-01 DOI: 10.1016/j.jtho.2025.03.020
Marisa E. Aikins , Abdullah Saeed , Derek Nancarrow , Sydney Malawer , Tejas Thiyagarajan , Andrew Yu , Sofia E. Merajver , Kiran Lagisetty
{"title":"PP01.13 Temporal Immune Evolution in a Murine EML4-ALK NSCLC Model: Genomic, Proteomic, and Drug Co-Culture Characterization","authors":"Marisa E. Aikins , Abdullah Saeed , Derek Nancarrow , Sydney Malawer , Tejas Thiyagarajan , Andrew Yu , Sofia E. Merajver , Kiran Lagisetty","doi":"10.1016/j.jtho.2025.03.020","DOIUrl":"10.1016/j.jtho.2025.03.020","url":null,"abstract":"","PeriodicalId":17515,"journal":{"name":"Journal of Thoracic Oncology","volume":"20 4","pages":"Pages S7-S8"},"PeriodicalIF":21.0,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143759394","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
PP01.03 Characterization of Mutated KRAS Genotype and Clinical Outcomes in Patients With Advanced NSCLC Treated With Mecbotamab Vedotin, a CAB-AXL-ADC
IF 21 1区 医学
Journal of Thoracic Oncology Pub Date : 2025-04-01 DOI: 10.1016/j.jtho.2025.03.011
Julia Rotow , Grace K. Dy , Edwin Yau , Elaine Shum , Mariam Alexander , Karen L. Reckamp , Roland Leung , Dariusz M. Kowalski , Jose Fuentes Pradera , Jon Zugazagoitia Fraile , Kyechin Chen , Kartik Aysola , D. Ross Camidge
{"title":"PP01.03 Characterization of Mutated KRAS Genotype and Clinical Outcomes in Patients With Advanced NSCLC Treated With Mecbotamab Vedotin, a CAB-AXL-ADC","authors":"Julia Rotow , Grace K. Dy , Edwin Yau , Elaine Shum , Mariam Alexander , Karen L. Reckamp , Roland Leung , Dariusz M. Kowalski , Jose Fuentes Pradera , Jon Zugazagoitia Fraile , Kyechin Chen , Kartik Aysola , D. Ross Camidge","doi":"10.1016/j.jtho.2025.03.011","DOIUrl":"10.1016/j.jtho.2025.03.011","url":null,"abstract":"","PeriodicalId":17515,"journal":{"name":"Journal of Thoracic Oncology","volume":"20 4","pages":"Pages S3-S4"},"PeriodicalIF":21.0,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143759489","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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