Journal of the Practice of Cardiovascular Sciences最新文献_第9页

Double whammy: Rheumatic heart disease associated with left ventricular noncompaction 双重打击:风湿性心脏病与左心室不致密

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Journal of the Practice of Cardiovascular Sciences Pub Date : 2021-01-01 DOI: 10.4103/jpcs.jpcs_82_20

Antara Banerji, Pradyot Tiwari

引用次数: 1

COVID-19 and cardiac health: A review COVID-19与心脏健康:综述

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Journal of the Practice of Cardiovascular Sciences Pub Date : 2021-01-01 DOI: 10.4103/jpcs.jpcs_90_20

Avinash Mani, V. Ojha, M. Dubey

{"title":"COVID-19 and cardiac health: A review","authors":"Avinash Mani, V. Ojha, M. Dubey","doi":"10.4103/jpcs.jpcs_90_20","DOIUrl":"https://doi.org/10.4103/jpcs.jpcs_90_20","url":null,"abstract":"The ongoing novel coronavirus pandemic has caused a serious impact on patients suffering from cardiovascular disorders as they are predisposed to COVID infection as well as to exacerbation of their preexisting conditions which can prove to be fatal. Novel coronavirus disease-2019 (nCOVID-19) has a varied effect on the cardiac system ranging from myocardial injury to thromboembolic complications. A significant proportion of patients are noted to have comorbidities. Human angiotensin-converting enzyme 2 (ACE 2) receptor is considered the target of the severe acute respiratory syndrome coronavirus 2 (SARS-Cov-2). SARS-Cov-2 leads to imbalance in RAAS activity which is responsible for target organ damage. Recombinant ACE 2 has been shown to restore ACE 2 levels in explanted hearts and restore balanced RAAS activity. nCOVID-19 can have varied cardiac manifestations ranging from acute coronary syndrome to heart failure, arrhythmias, pulmonary thromboembolism, and pericarditis. The current nCOVID-19 pandemic has led to changes in management strategies for cardiovascular diseases. Patients with ST-elevation myocardial infarction can be fibrinolysed when a primary percutaneous coronary intervention facility with adequate protection is not available. Angiotensin-converting enzyme inhibitor/angiotensin receptor blocker needs to be continued in patients with hypertension. Continuity of care for patients with chronic cardiovascular illness needs to be maintained. Management of cardiovascular emergencies needs to be done in a way which ensures the safety of health-care professionals and prevents infection transmission. Strict prevention of infection and health control measures will help to prevent spread of infection and reduce disease incidence.","PeriodicalId":17503,"journal":{"name":"Journal of the Practice of Cardiovascular Sciences","volume":"7 1","pages":"24 - 30"},"PeriodicalIF":0.1,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42605414","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

A comparative assessment of the severity of coronary artery disease in patients with low ankle–Brachial index and normal ankle–Brachial index: An angiography-based cross-sectional observational-analytical study (CADLABI study) 低踝肱指数和正常踝肱指数患者冠状动脉疾病严重程度的比较评估:一项基于血管造影的横断面观察分析研究(CADLABI研究)

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Journal of the Practice of Cardiovascular Sciences Pub Date : 2021-01-01 DOI: 10.4103/jpcs.jpcs_91_20

A. Sharma, Mohitosh Kejriwal, S. Sinha, M. Razi, U. Pandey, P. Shukla, R. Thakur, C. Verma, V. Krishna

{"title":"A comparative assessment of the severity of coronary artery disease in patients with low ankle–Brachial index and normal ankle–Brachial index: An angiography-based cross-sectional observational-analytical study (CADLABI study)","authors":"A. Sharma, Mohitosh Kejriwal, S. Sinha, M. Razi, U. Pandey, P. Shukla, R. Thakur, C. Verma, V. Krishna","doi":"10.4103/jpcs.jpcs_91_20","DOIUrl":"https://doi.org/10.4103/jpcs.jpcs_91_20","url":null,"abstract":"Objectives: The ankle–brachial index (ABI) is an efficient tool and an indicator of generalized atherosclerosis. Still, there is uncertainty regarding the severity of coronary artery disease (CAD) in patients having low ABI. The uniqueness of this study is that it is the first largest study done with the aim to determine the severity of CAD in the form of a number of involvements of coronary vessel in patients with low ABI. Materials and Methods: It is a hospital-based cross-sectional observational-analytical study. A total of 500 patients of suspected CAD were recruited. ABI was measured first and then all patients were sent for coronary angiography. Based on ABI values, patients were divided into two groups, i.e., Group A (patients with low ABI or ABI ≤0.9) and Group B (patients with normal ABI or ABI >0.9). Results: Twenty-three, i.e., 4.6% of patients had ABI <0.9. All patients having low ABI had CAD. In assessing CAD severity, it was reported that in Group A, triple-vessel disease (TVD) was present in 65.2% (P = 0.0001), double-vessel disease in 21.7% (P = 0.72), single-vessel disease in 8.6% (P = 0.06), and noncritical CAD in 4.3% (P = 0.9) as compared to Group B. In patients with Group A, 52.1% were smoker (P = 0.01), 69.5% have increased body mass index (P = 0.71), 43.4% have a history of hypertension (P = 0.73), and 60.8% were diabetic (P = 0.0005). Conclusion: CAD is widely prevalent almost in all patients with low ABI and more than half of these patients have TVD on angiographic assessment.","PeriodicalId":17503,"journal":{"name":"Journal of the Practice of Cardiovascular Sciences","volume":"7 1","pages":"54 - 59"},"PeriodicalIF":0.1,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43008018","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 2

Calcific severe rheumatic mitral valve stenosis disguising as a “pseudoprosthesis”: An imaging vignette 钙化严重风湿性二尖瓣狭窄伪装成“假体”:一个影像小特写

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Journal of the Practice of Cardiovascular Sciences Pub Date : 2021-01-01 DOI: 10.4103/jpcs.jpcs_80_20

Akhlaque Ahmed, A. Sahu, A. Kapoor

引用次数: 0

Left ventricular thrombus in patients with COVID-19 – A case series 新冠肺炎患者左心室血栓——一个病例系列

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Journal of the Practice of Cardiovascular Sciences Pub Date : 2021-01-01 DOI: 10.4103/jpcs.jpcs_87_20

P. Jariwala, Arshad Punjani, H. Boorugu, M. Reddy

{"title":"Left ventricular thrombus in patients with COVID-19 – A case series","authors":"P. Jariwala, Arshad Punjani, H. Boorugu, M. Reddy","doi":"10.4103/jpcs.jpcs_87_20","DOIUrl":"https://doi.org/10.4103/jpcs.jpcs_87_20","url":null,"abstract":"Scarred culprit vessel territory secondary to nonreperfused myocardial infarctions (MIs), nonischemic cardiomyopathy, left ventricular (LV) noncompaction, endomyocardial fibrosis, and long-standing arrythmias are usually causes of LV thrombus (LVT) formation. However, in the setting of MI, large infarctions, apical akinesia or dyskinesia, LV aneurysms are often predisposed t'o the formation of LVT. The hypercoagulable or inflammatory disorder can rarely predispose to the formation of LVT. In early prethrombolytic and thrombolytic periods, LVT was present in 20%–50% of patients in the context of acute MI, more commonly in acute anterior or apical MI. While the incidence of LVT has dropped in recent times, its identification is expected to rise during the COVID-19 pandemic. Patients with chest pain are more likely to delay initial hospitalization because of a fear of contracting COVID-19. Infection with COVID-19 was associated with the remarkably hypercoagulable state which increased the risk of the early development of LVT in the setting of MI or underlying prethrombotic conditions. We present a series of four cases in which COVID-19 and cardiovascular disease were characterized by various configurations of large LVT.","PeriodicalId":17503,"journal":{"name":"Journal of the Practice of Cardiovascular Sciences","volume":"7 1","pages":"69 - 75"},"PeriodicalIF":0.1,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43734953","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 2

Hydroxychloroquine and azithromycin use in COVID-19 era and cardiovascular concerns: Current perspective 新冠肺炎时代羟氯喹和阿奇霉素的使用与心血管问题：当前观点

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Journal of the Practice of Cardiovascular Sciences Pub Date : 2021-01-01 DOI: 10.4103/jpcs.jpcs_85_20

A. Kapoor, A. Sahu

{"title":"Hydroxychloroquine and azithromycin use in COVID-19 era and cardiovascular concerns: Current perspective","authors":"A. Kapoor, A. Sahu","doi":"10.4103/jpcs.jpcs_85_20","DOIUrl":"https://doi.org/10.4103/jpcs.jpcs_85_20","url":null,"abstract":"In the present era of coronavirus disease 2019 (COVID-19) pandemic, lack of an established and effective targeted therapy sans a vaccine is proving to be a major hurdle in containing the contagion. Hydroxychloroquine (HCQ), a widely used antimalarial and anti-inflammatory drug, has been proposed for coronavirus infection management by various drug regulatory authorities for emergency use including Indian Council of Medical Research. However, clinical safety concerns primarily regarding cardiovascular issues have been raised against HCQ usage, especially in relatively higher dosage in conjunction with azithromycin (AZM) coprescription. HCQ and to some extent, AZM have proven to be effective against COVID-19. Barring a small at-risk population for cardiovascular adverse effects, their clinical use in the treatment and prevention of COVID-19 was deemed to be beneficial and even recommended by various national and international representative societies including the World Health Organization, especially in high-risk individuals such as health-care workers and exposed contacts of coronavirus positive patients under due medical supervision. Multiple studies evaluating the anticoronaviral efficacy for prevention as well as for treatment prospect were conducted, but none could convincingly demonstrate a beneficial effect of HCQ with or without AZM on alleviating symptoms, shortening hospitalization, improving survival, or preventing disease transmission.","PeriodicalId":17503,"journal":{"name":"Journal of the Practice of Cardiovascular Sciences","volume":"7 1","pages":"78 - 82"},"PeriodicalIF":0.1,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42609965","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Critical care preparedness and conduct in COVID-2019 crisis 2019冠状病毒病危机中的重症监护准备和行为

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Journal of the Practice of Cardiovascular Sciences Pub Date : 2021-01-01 DOI: 10.4103/jpcs.jpcs_79_20

M. Sahu, Prateek Vaswani

{"title":"Critical care preparedness and conduct in COVID-2019 crisis","authors":"M. Sahu, Prateek Vaswani","doi":"10.4103/jpcs.jpcs_79_20","DOIUrl":"https://doi.org/10.4103/jpcs.jpcs_79_20","url":null,"abstract":"Background: COVID-19 pandemic has stirred an unexpected turmoil in health care worldwide. The strategic conduct of critical care would warrant an effective preparedness plan, thorough knowledge of the disease manifestations, and relevant therapeutic strategy to sail through this crisis. Methods: English medical literature with MeSh database was searched using the key words such as “COVID-19 pandemic,” “ICU preparedness,” “COVID-19 management,” “COVID-19 therapy,” and “COVID-19 systemic effects.” The relevant studies were included with significant inputs from interdepartmental meetings for the formulation of a plan. Results: The analysis of the respective studies highlighted the requirements of COVID-19 designated intensive care units (ICUs) with special provisions and the therapeutic agents being used in critical patients with emphasis on Remdesivir, Dexamethasone, Convalescent Plasma, and insight into newer agents. The systemic manifestations of COVID-19 requiring ICU care such as acute respiratory distress syndrome, myocardial injury, arrhythmias, hypercoagulable state, and acute renal dysfunction have been highlighted. The need of updating records with research protocols cannot be disregarded. The care of patients should not compromise the health-care personnel requirements. Conclusion: The evidence-based preparedness strategy can curtail the critical care crunch in COVID-19 management; however, institutional specific approach should be formulated.","PeriodicalId":17503,"journal":{"name":"Journal of the Practice of Cardiovascular Sciences","volume":"7 1","pages":"16 - 23"},"PeriodicalIF":0.1,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46232587","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Acute electrocardiographic changes during smoking and tobacco chewing: A Cross-sectional study 吸烟和咀嚼烟草时的急性心电图变化:一项横断面研究

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Journal of the Practice of Cardiovascular Sciences Pub Date : 2021-01-01 DOI: 10.4103/jpcs.jpcs_112_20

Himanshu Gupta, B. Bhargava, S. Seth, C. Pruthvi, S. Ramakrishnan

{"title":"Acute electrocardiographic changes during smoking and tobacco chewing: A Cross-sectional study","authors":"Himanshu Gupta, B. Bhargava, S. Seth, C. Pruthvi, S. Ramakrishnan","doi":"10.4103/jpcs.jpcs_112_20","DOIUrl":"https://doi.org/10.4103/jpcs.jpcs_112_20","url":null,"abstract":"Background: Smoking increases the risk of coronary artery disease. Very few studies have evaluated the temporal relationship of electrocardiographic changes with smoking. We sought to study and compare the electrocardiogram (ECG) changes during smoking and tobacco chewing in current smokers and tobacco chewers presenting with atypical chest pain with either negative or mild positive exercise ECG test (treadmill test [TMT]). Materials and Methods: We screened male smokers and tobacco chewers with atypical chest pain with TMT. A total of 60 patients, 30 in each group in whom TMT was either negative or mildly positive, underwent a 24-h Holter monitoring. We asked patients to note down their time of smoking and tobacco chewing along with the timing of symptoms if any. Results: All patients were male with an average age of 45 years in smokers and 42 years in the tobacco chewer group. The mean number of cigarettes consumed was 6 ± 2.8 and tobacco chewed was 5 ± 4.7 g/day. Heart rate (HR) in smokers increased from 82.5 ± 14.56/min 10 min before smoking to 90.63 ± 15.34/min, during smoking with peak HR achieved at the time of smoking (P < 0.0001). HR in the tobacco chewers peaked at 10 min after chewing from 80.62 ± 13.52/min 10 min before to 87.89 ± 13.86/min 10 min after chewing (P < 0.0001). Smoking was associated with a significant increase in supraventricular ectopics (VEs) from 3.98/h before smoking to 7.43/h during and 6.92/h after smoking (P < 0.0001). Two patients in the smoker subgroup had spontaneous smokeless tobacco -T changes lasting for 10–25 min. Smoking was associated with a significant decrease in HR variability (HRV) index than the controls (P = 0.023). Tobacco chewing was not associated with any significant changes in the HRV parameter. Conclusions: Smoking and tobacco chewing both significantly increase the HR acutely. Smoking leads to an increase in both supraventricular and VEs. We observed reduced HRV in patients who smoked cigarettes.","PeriodicalId":17503,"journal":{"name":"Journal of the Practice of Cardiovascular Sciences","volume":"7 1","pages":"41 - 46"},"PeriodicalIF":0.1,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48668182","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Pedicled omental wrapping of ascending aortic graft following mediastinitis 纵隔炎后带蒂网膜包裹升主动脉移植物

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Journal of the Practice of Cardiovascular Sciences Pub Date : 2021-01-01 DOI: 10.4103/jpcs.jpcs_98_20

Y. Arora, V. Devagourou, Ratnesh Kumar

引用次数: 0

Pulmonary artery hypertension: A bedside review 肺动脉高压:床边回顾

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Journal of the Practice of Cardiovascular Sciences Pub Date : 2021-01-01 DOI: 10.4103/jpcs.jpcs_110_20

Mohit M. Bhagwati, R. Mehrotra

引用次数: 0