Journal of the Practice of Cardiovascular Sciences最新文献

Clinical presentation and pattern of cardiac involvement in patients with rheumatic heart disease: A prospective observational study 风湿性心脏病患者心脏受累的临床表现和模式:一项前瞻性观察研究

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Journal of the Practice of Cardiovascular Sciences Pub Date : 2023-05-01 DOI: 10.4103/jpcs.jpcs_7_23

A. Mohan, M. Arjun, D. Rajasekhar, A. Chandra, BVijayalakshmi Devi, S. Sangaraju

{"title":"Clinical presentation and pattern of cardiac involvement in patients with rheumatic heart disease: A prospective observational study","authors":"A. Mohan, M. Arjun, D. Rajasekhar, A. Chandra, BVijayalakshmi Devi, S. Sangaraju","doi":"10.4103/jpcs.jpcs_7_23","DOIUrl":"https://doi.org/10.4103/jpcs.jpcs_7_23","url":null,"abstract":"Context: Rheumatic heart disease (RHD). Aim: The aim of the study was to study the clinical presentation and pattern of cardiac involvement in adult patients with RHD. Settings and Design: This was a prospective observational study from a tertiary care hospital in South India. Subjects and Methods: Consecutive adult patients diagnosed with and treated for RHD in our tertiary care teaching hospital in Tirupati were screened for inclusion. In all patients, details of appropriate laboratory and imaging investigations that have been carried out were noted. Statistical Analysis Used: Descriptive statistics (frequencies, mean standard deviation, and median [interquartile range (IQR)]) were reported. Results: A total of 120 patients were enrolled. Their mean age was 45.7–12.2 years; there were 79 females. The median (IQR) follow-up was 364 (156–702) weeks. Single-valve disease was seen in 51.7% (n = 62); others (n = 58) had multivalvular disease (mitral stenosis [MS] + aortic regurgitation [AR] [n = 47, 81%] and mitral regurgitation + AR [n = 11, 19%]). Among patients with single-valve involvement, 58 (93.5%) had mitral valve disease. Overall, 116 of 120 (96.6%) patients had mitral valve involvement. Among patients with mitral valve disease (n = 116), MS was severe in 62 (51.6%). Atrial fibrillation was evident in 59 (49.2%) patients; of these, 8 had cardioembolic strokes. Forty-four (36.7%) had undergone percutaneous transvenous mitral commissurotomy. Prosthetic mitral valve obstruction was observed in 2/20 patients who had undergone mitral valve replacement or double-valve replacement. Conclusions: In patients with RHD, mitral valve involvement (either alone or in combination with the aortic valve) was most common; MS was most common.","PeriodicalId":17503,"journal":{"name":"Journal of the Practice of Cardiovascular Sciences","volume":"9 1","pages":"116 - 120"},"PeriodicalIF":0.1,"publicationDate":"2023-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48346439","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Leadless pacemaker – A savior in crisis 无铅起搏器-危机中的救世主

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Journal of the Practice of Cardiovascular Sciences Pub Date : 2023-05-01 DOI: 10.4103/jpcs.jpcs_31_23

Ashwin Tumkur, Golla Sudhakar

引用次数: 0

Isolated double orifice mitral valve: An extremely rare cardiac anomaly 孤立性双孔二尖瓣：一种极为罕见的心脏异常

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Journal of the Practice of Cardiovascular Sciences Pub Date : 2023-05-01 DOI: 10.4103/jpcs.jpcs_85_22

Maharshi Patel, T. Rao, S. Acharya, S. Shukla, S. Sushanth Kumar

引用次数: 0

Prognostic markers in heart failure: Further insights 心力衰竭的预后标志物：进一步的见解

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Journal of the Practice of Cardiovascular Sciences Pub Date : 2023-05-01 DOI: 10.4103/jpcs.jpcs_43_23

R. Magoon, Devishree Das

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Radial artery pseudoaneurysm following transradial percutaneous coronary intervention 经桡动脉经皮冠状动脉介入治疗后桡动脉假性动脉瘤

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Journal of the Practice of Cardiovascular Sciences Pub Date : 2023-05-01 DOI: 10.4103/jpcs.jpcs_49_23

Bharath Konda, Krishna Reddy Parvathareddy, Praveen Nagula, Z. Hussain

引用次数: 0

Efficacy and safety of rivaroxaban in prevention and therapy of thromboembolic events in patients with nonvalvular atrial fibrillation 利伐沙班预防和治疗非瓣膜性心房颤动患者血栓栓塞事件的有效性和安全性

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Journal of the Practice of Cardiovascular Sciences Pub Date : 2023-05-01 DOI: 10.4103/jpcs.jpcs_40_23

T. Preradović, S. Miljković, Ljiljana Kos, A. Šukalo, U. Glamočlija, A. Avdić, Meliha Mehić

{"title":"Efficacy and safety of rivaroxaban in prevention and therapy of thromboembolic events in patients with nonvalvular atrial fibrillation","authors":"T. Preradović, S. Miljković, Ljiljana Kos, A. Šukalo, U. Glamočlija, A. Avdić, Meliha Mehić","doi":"10.4103/jpcs.jpcs_40_23","DOIUrl":"https://doi.org/10.4103/jpcs.jpcs_40_23","url":null,"abstract":"Context: Rivaroxaban is an oral direct factor Xa inhibitor reducing the risk of systemic embolism and stroke in patients with nonvalvular atrial fibrillation. Aims: The primary objective was to evaluate the effectiveness of rivaroxaban therapy in reducing the risk of systemic embolism and stroke in patients with nonvalvular atrial fibrillation, whereas secondary objectives were to monitor therapy safety and the patients' adherence to treatment. Settings and Design: The prospective, postmarketing clinical trial was conducted on patients with nonvalvular atrial fibrillation with one or more risk factors, such as congestive heart failure, hypertension, and diabetes mellitus, who suffered a stroke or a transient ischemic attack. Subjects and Methods: At the baseline visit, the CHA2DS2 score was determined, and therapy was introduced. At three control visits (1, 3, and 6 months after baseline), systemic embolism, stroke, bruises, or bleeding occurrences were recorded. Furthemore, adverse events were monitored, and the Morisky score (MMAS-8) for treatment compliance was determined. Results were compared to previous studies. Results: The study included 471 patients. The incidence rate in events per 100 patient-years (95% confidence interval) was 2.6 (0.1–5.1) for systemic embolism and 4.3 (1.6–7.0) for stroke. The most common form of bleeding during rivaroxaban therapy was epistaxis. Adverse events were reported in 12 (2.7%) patients. Therapy adherence was in the range of medium adherence for the entire study period, with the average score decreasing significantly from the 1st to 6th months (P < 0.001). Conclusions: Rivaroxaban showed good efficacy and safety in reducing the risk of systemic embolism and stroke in patients with nonvalvular atrial fibrillation including patients with comorbidities.","PeriodicalId":17503,"journal":{"name":"Journal of the Practice of Cardiovascular Sciences","volume":"9 1","pages":"110 - 115"},"PeriodicalIF":0.1,"publicationDate":"2023-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49590686","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

A simple and innovative repair of an incidentally discovered sinus of valsalva aneurysm during aortic valve replacement 主动脉瓣置换术中偶然发现的主动脉窦动脉瘤的简单和创新修复

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Journal of the Practice of Cardiovascular Sciences Pub Date : 2023-05-01 DOI: 10.4103/jpcs.jpcs_46_23

Sarvesh Kumar, Vivek Tewarson, M. Hakim, Bhupendra Kumar, K. Rahul, Shobhit Kumar, Sushil Singh

引用次数: 0

Aspirin strategy for secondary prevention of atherosclerotic cardiovascular diseases: A narrative review 阿司匹林二级预防动脉粥样硬化性心血管疾病的策略：叙述性综述

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Journal of the Practice of Cardiovascular Sciences Pub Date : 2023-05-01 DOI: 10.4103/jpcs.jpcs_46_22

Nischal Hegde, Navin Mathew

引用次数: 0

Acute coronary syndrome in young (≤45 years) patients: An observational study 年轻（≤45岁）患者的急性冠状动脉综合征：一项观察性研究

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Journal of the Practice of Cardiovascular Sciences Pub Date : 2023-05-01 DOI: 10.4103/jpcs.jpcs_3_23

Chandrashekhar Pandey, Reena Singh, Pankaj Vasantrao Talokar, Rujuta Parikh, Gaurav Singh

{"title":"Acute coronary syndrome in young (≤45 years) patients: An observational study","authors":"Chandrashekhar Pandey, Reena Singh, Pankaj Vasantrao Talokar, Rujuta Parikh, Gaurav Singh","doi":"10.4103/jpcs.jpcs_3_23","DOIUrl":"https://doi.org/10.4103/jpcs.jpcs_3_23","url":null,"abstract":"Background: Acute coronary syndrome (ACS) is witnessing a demographic transition with increasing prevalence among younger individuals (≤45 years). Hence, this study was designed to evaluate the clinical features, risk factors, and angiographic profile of young (aged ≤ 45 years) patients with ACS and to compare it with the older (aged >45 years) patients with ACS. Materials and Methods: An observational study was conducted at a tertiary care center in India from July 2020 to December 2021. A total of 157 patients were enrolled, among which 90 patients were included in cases (group-I). The inclusion criteria were patients presenting with ACS aged between 18 and 45 years. There were two control groups, including 34 patients with ACS (aged >45 years) in Group II and 33 healthy volunteers in Group III (aged 18–45 years). Baseline demographic details, risk factors, and angiographic profile of patients with ACS in each group were recorded and compared. Results: Mean age of Group I was 39.79 ± 5.15 years and of Group II was 59.74 ± 8.21 years. Smoking (P = 0.027) and family history of coronary artery disease (P = 0.022) were the significant risk factors of ACS in Group I. Compared to non-ST elevation myocardial infarction (16.7%), ST-elevation myocardial infarction (83.3%) was predominant among younger patients with ACS. Single-vessel disease was prevalent among younger patients (62.2%) as compared to older patients with ACS (41.20%). Conclusion: Younger patients with ACS exhibited a distinct clinical and angiographic profile compared to older patients with ACS.","PeriodicalId":17503,"journal":{"name":"Journal of the Practice of Cardiovascular Sciences","volume":"9 1","pages":"121 - 126"},"PeriodicalIF":0.1,"publicationDate":"2023-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42982779","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Venous thromboembolism and cardiopulmonary involvement in Covid 2019 patients: A retrospective observational study 新冠肺炎2019患者的静脉血栓栓塞和心肺受累：一项回顾性观察性研究

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Journal of the Practice of Cardiovascular Sciences Pub Date : 2023-05-01 DOI: 10.4103/jpcs.jpcs_24_23

Vivek Kumar, Reena Anand, S. Dhir, B. Aggarwal

{"title":"Venous thromboembolism and cardiopulmonary involvement in Covid 2019 patients: A retrospective observational study","authors":"Vivek Kumar, Reena Anand, S. Dhir, B. Aggarwal","doi":"10.4103/jpcs.jpcs_24_23","DOIUrl":"https://doi.org/10.4103/jpcs.jpcs_24_23","url":null,"abstract":"Context: The context of the study was venous thromboembolism (VTE) in coronavirus disease 2019 (COVID-19) patients. Aim: The purpose of the study was to understand the prevalence of thrombotic events (pulmonary embolism [PE] and deep-vein thrombosis [DVT]) and right ventricular (RV) dysfunction (RVD) in patients with COVID-19. Settings and Design: Retrospective observational study, Max Hospital, New Delhi, India. Materials and Methods: This study was undertaken in 504 diagnosed COVID-19 adult patients of both genders in the age groups (>40 years and 40 years) during the COVID first and second waves in India. The hospital EMR database of the admitted COVID patients was extracted. Based on the study criteria, the parameters assessed were: D-dimer, CTSS scoring, DVT, RVD, and nature of hospitalization. Statistical Analysis Used: Quantitative variables were expressed in terms of mean and standard deviation. The significance of the association between different variables was evaluated by the Chi-square test. The significance of the difference in age and CTSS score between different categories of PE and DVT was tested by the Student's t-test. Results: The mean age of the patients was 57.13 years. The mean D-dimer level was 502.95 ng/mL. A PE was reported in 101 patients. The severity of the lung involvement as assessed on computed tomography pulmonary angiography was predominant in the bilateral segmental branch (70%), with a mean CTSS score of 14.47, 7.37. DVT was reported in 48 (9.5%) patients. RVD was observed in 14 (2.8%) patients. A significant correlation was found between PE and hospitalization (83.2%, P = 0.003), CTSS (20.07%, P = 0.037, confidence interval 0.10–3.31), and DVT (33.7%, P = 0.001). The prevalence of PE (20.03%) and VTE was 6.7%. RVD was reported in 2.8% of the cases. Conclusion: Our study validates the increased risk of VTE in COVID-19 patients. These findings will be useful to researchers and medical practitioners caring for COVID-19 patients.","PeriodicalId":17503,"journal":{"name":"Journal of the Practice of Cardiovascular Sciences","volume":"9 1","pages":"132 - 137"},"PeriodicalIF":0.1,"publicationDate":"2023-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41489535","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0