{"title":"Concerns of non-hodgkin's lymphoma in open-heart surgery for rheumatic heart disease: A case report and review of literature","authors":"Anish Gupta, Anshuman Darbari, U. Nath, R. Abisho","doi":"10.4103/jpcs.jpcs_79_22","DOIUrl":"https://doi.org/10.4103/jpcs.jpcs_79_22","url":null,"abstract":"There are concerns regarding safe conduct of open-heart surgery in a patient with hematological malignancy, both in intraoperative and postoperative management of the patient. There is a paucity of literature regarding this problem and limited data have been published regarding the conduct of coronary artery bypass surgery on pump in a patient with hematological malignancies. We describe our experience in a patient with rheumatic heart disease with non-Hodgkin's lymphoma requiring mitral valve replacement.","PeriodicalId":17503,"journal":{"name":"Journal of the Practice of Cardiovascular Sciences","volume":"9 1","pages":"95 - 98"},"PeriodicalIF":0.1,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43139021","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Abhay Kumar, G. Keshavamurthy, Navreet Singh, Balwinder Singh, R. Vaidya, Tanmoy Roy, S. Singh, Ankush Gupta, N. Bajaj, P. Barwad, Ekambir Singh
{"title":"Role of yoga in prehypertension and hypertension","authors":"Abhay Kumar, G. Keshavamurthy, Navreet Singh, Balwinder Singh, R. Vaidya, Tanmoy Roy, S. Singh, Ankush Gupta, N. Bajaj, P. Barwad, Ekambir Singh","doi":"10.4103/jpcs.jpcs_39_22","DOIUrl":"https://doi.org/10.4103/jpcs.jpcs_39_22","url":null,"abstract":"Background: The high prevalence of hypertension in India necessitates both pharmacological and nonpharmacological measures to control it. Here, we report the findings of a study to investigate the effectiveness of yoga therapy in lowering blood pressure (BP) in prehypertensive and hypertensive individuals. Methods: This was a single center, nonrandomized controlled clinical trial, of 200 hypertensives and 100 prehypertensives patients. The control group received the prescribed antihypertensive and lifestyle modification while the yoga group was additionally taught simple yogic exercise by a trained yoga teacher. This training included intensive supervised phase 2-h training sessions in Ujjayi breathing, Bhastrika Pranayama and chanting of “Om” for 10 lessons, followed by self-performed yogic exercise at home for 1 h till the end of study at 1 year. Results: The systolic BP (SBP) in the hypertensive yoga group was significantly lower (t = 3.04, P < 0.01) than the control group at 6 months, but not so at 1 year (SBP t = 0.53, P > 0.05). In the prehypertensive participants, at 6 months (t = 5.85, P = 0.00), and 1 year (t = 6.385, P < 0.05) a significant difference was observed between SBP of the two groups However, no significant difference was observed between the diastolic BP among hypertensives or prehypertensives at 6 months and 1 year. Conclusion: Our present study indicates that yoga therapy is a viable adjunct to pharmacological intervention to reduce SBP in the management of hypertension and prehypertension and that yoga should be incorporated in the treatment regime of such patients, specifically for individuals who have prehypertension.","PeriodicalId":17503,"journal":{"name":"Journal of the Practice of Cardiovascular Sciences","volume":"9 1","pages":"53 - 59"},"PeriodicalIF":0.1,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49411069","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
S. Kumari, U. Sharma, Deepika Jindal, Traymbak Basak
{"title":"A narrative review on serum biomarkers of cardiac fibrosis","authors":"S. Kumari, U. Sharma, Deepika Jindal, Traymbak Basak","doi":"10.4103/jpcs.jpcs_19_23","DOIUrl":"https://doi.org/10.4103/jpcs.jpcs_19_23","url":null,"abstract":"Myocardial fibrosis is the excessive deposition of extracellular matrix (ECM) proteins in the cardiac interstitium leading to pathological conditions of the heart. The objective is to understand the pathophysiology of cardiac fibrosis and the quest for serum biomarkers that will assist in early diagnosis before the occurrence of major cardiac events. There are many serum biomarkers that get elevated highlighting ECM remodeling during cardiac fibrosis. Lysyl oxidase like -2 is one such ECM protein, plays a crucial role in the up-regulation of TGF - β, the transformation of cardiac fibroblast to myoblast, the migration of collagen, and cross-linking of collagen and elastin. However, assessment of lysyl oxidase like-2 (LOXL-2) in different pathologically driven cardiac fibrosis is limited. Also, none of the serum biomarkers has proved to be the most accurate diagnostic tool for assessing fibrosis independently; hence, meticulous, less invasive, and cost-effective serum biomarkers need to be scrutinized. Hence lysyl oxidase Like-2 (LOXL-2) in combination with other serum biomarkers like PICP/PINP/TIMP-1/ST-2, or Galectin-3 can be combined to assess the presence of fibrosis in the heart. This review includes the journal, articles, and research paper on cardiac fibrosis which was published in the last 10–15 years to highlight the huge gap in the treatment of cardiac fibrosis and the need for a new combination of biomarkers with better prognostic and diagnostic value.","PeriodicalId":17503,"journal":{"name":"Journal of the Practice of Cardiovascular Sciences","volume":"9 1","pages":"24 - 36"},"PeriodicalIF":0.1,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48507282","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
S. Sarkar, B. Majumder, Debasish Mohapatra, R. Ghosh
{"title":"Immature mediastinal teratoma mimicking as pulmonary stenosis – A rare presentation","authors":"S. Sarkar, B. Majumder, Debasish Mohapatra, R. Ghosh","doi":"10.4103/jpcs.jpcs_82_22","DOIUrl":"https://doi.org/10.4103/jpcs.jpcs_82_22","url":null,"abstract":"Anterior mediastinal teratoma can externally compress the pulmonary artery, which can present with symptoms of pulmonary stenosis rarely. We have reported a case of a 47-year-old male with immature mediastinal teratoma presenting as pulmonary stenosis. Initial physical examination revealed an ejection systolic murmur in the pulmonary area. With suspicion of valvular heart disease, the patient was referred to our cardiology department. Chest X-ray shows mass just above the left hilar zone. Two-dimensional echocardiography shows a mediastinal mass compressing the pulmonary trunk causing an obstruction. Contrast-enhanced computed tomography of thorax and magnetic resonance study confirmed the mediastinal mass. Fine-needle aspiration cytology of the mass suggestive of immature teratoma. The patient was transferred to the cardiothoracic vascular surgery department for further management. Mediastinal mass can mimic valvular heart disease with symptoms of cardiovascular pathology. Proper investigations for diagnostic clarity and prompt management are crucial in these conditions.","PeriodicalId":17503,"journal":{"name":"Journal of the Practice of Cardiovascular Sciences","volume":"9 1","pages":"60 - 63"},"PeriodicalIF":0.1,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42563474","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
K. Atilgan, B. Onuk, E. Zafer Cengiz, F. Yesil, A. Çolak, T. Aybek
{"title":"LMCA aneurysm and a fistula resulting with a giant extracardiac aneurysm","authors":"K. Atilgan, B. Onuk, E. Zafer Cengiz, F. Yesil, A. Çolak, T. Aybek","doi":"10.4103/jpcs.jpcs_13_23","DOIUrl":"https://doi.org/10.4103/jpcs.jpcs_13_23","url":null,"abstract":"A 54-year-old, asymptomatic, disease-free female patient was operated for an incidentally detected left main coronary artery aneurysm (CAA) associated with fistula to a giant aneurysm associated with the right atrium (RA). The patient had an extremely rare left main CAA and a fistula connection of a giant aneurysm connecting to the RA.","PeriodicalId":17503,"journal":{"name":"Journal of the Practice of Cardiovascular Sciences","volume":"9 1","pages":"67 - 69"},"PeriodicalIF":0.1,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"45204090","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
R. Chatterjee, Aitihya Chakraborty, K. Sarkar, N. Pramanik, Shatavisa Mukherjee
{"title":"Tuberculosis with new onset of diabetes and hypertension following recovery from coronavirus disease 2019 infection: A case series","authors":"R. Chatterjee, Aitihya Chakraborty, K. Sarkar, N. Pramanik, Shatavisa Mukherjee","doi":"10.4103/jpcs.jpcs_14_23","DOIUrl":"https://doi.org/10.4103/jpcs.jpcs_14_23","url":null,"abstract":"The sign and symptoms of coronavirus disease 2019 (COVID-19) and infectious disease caused by severe acute respiratory syndrome coronavirus 2 are not only restricted to the respiratory system but includes a myriad of clinical manifestations involving various systems. There are various sequelae of COVID-19 reported. Here, we report a series of three cases of tuberculosis along with new onset of diabetes mellitus and hypertension in previously euglycemic, normotensive patients following recovery from COVID-19.","PeriodicalId":17503,"journal":{"name":"Journal of the Practice of Cardiovascular Sciences","volume":"9 1","pages":"64 - 66"},"PeriodicalIF":0.1,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"45569660","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Parth Godhiwala, S. Sushanth Kumar, S. Acharya, M. Patel
{"title":"Comparative analysis of different prognostic markers in predicting outcome in advanced heart failure","authors":"Parth Godhiwala, S. Sushanth Kumar, S. Acharya, M. Patel","doi":"10.4103/jpcs.jpcs_17_23","DOIUrl":"https://doi.org/10.4103/jpcs.jpcs_17_23","url":null,"abstract":"Introduction: Heart failure (HF) is a debilitating condition with an adverse outcome, especially during the advanced stage having higher morbidity and mortality rates. Various parameters have been used as prognostic markers in advanced HF. This study highlights about the comparative analysis of different prognostic markers in predicting mortality in advanced HF. Methods: This prospective observational study was conducted in patients of advanced HF admitted to the department of medicine intensive care unit in a rural tertiary care hospital from 2018 to 2020. Advanced HF was diagnosed using the updated HF Association-European Society of Cardiology criteria. The serum N-terminal pro-B-type natriuretic peptide (NT-proBNP), six-minute walk test (6MWT), left ventricular ejection fraction (LVEF), estimated glomerular filtration rate, and glycosylated hemoglobin type A1c levels were measured on admission. Receiver operating characteristic (ROC) curve was also studied for the above-mentioned variables, and the area under ROC curve (AUROC) was also determined. Results: Seventy-five patients with an average age of 60.55 ± 14.04 years were evaluated. Out of 75, 48 (64%) were male and 27 (36%) were female. There was inhospital mortality in 20 (26.67%) patients. The mean NT-proBNP levels among the mortality group was 9826.95 ± 3485.10 pg/mL, while in nonmortality group, it was 6135.40 ± 2342.77 pg/mL (P = 0.001). The cutoff range in this study for on-admission serum NT-proBNP levels was 8990 pg/mL, with AUROC of 0.81, the sensitivity of 70.0%, and specificity of 90.9%. In multiple regression analysis keeping mortality as the dependent variable, it was seen that variables NT-proBNP, 6MWT (<300 m), and LVEF were significantly associated with mortality. Conclusion: Serum NT-proBNP and 6MWT (<300 m) were important predictors of mortality in advanced HF.","PeriodicalId":17503,"journal":{"name":"Journal of the Practice of Cardiovascular Sciences","volume":"9 1","pages":"46 - 52"},"PeriodicalIF":0.1,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42178031","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Vishal Agrawal, P. Garg, P. Vyas, Joshi Hasit, Amit Mishra
{"title":"Hybrid approach for postclassical blalock–Taussig shunt tetralogy","authors":"Vishal Agrawal, P. Garg, P. Vyas, Joshi Hasit, Amit Mishra","doi":"10.4103/jpcs.jpcs_57_22","DOIUrl":"https://doi.org/10.4103/jpcs.jpcs_57_22","url":null,"abstract":"In developing countries, we still come across occasional patients who have undergone classic Blalock–Taussig shunt (CBTS) previously. We present a case of 23-year-old female with tetralogy of Fallot who had undergone CBTS operation at the age of 1 year and is now presented for total correction. Takedown of CBTS during surgery has catastrophic complications during looping and ligation of shunt due to extensive collateralization. We, therefore, took a hybrid approach for the patient. The CBTS was first blocked with the balloon, followed by surgical intracardiac repair, and finally, by device closure of CBTS.","PeriodicalId":17503,"journal":{"name":"Journal of the Practice of Cardiovascular Sciences","volume":"9 1","pages":"84 - 86"},"PeriodicalIF":0.1,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42230713","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Jayarama Pai, S. Mukkannavar, Bharat Siddharth, R. Geethika, D. Shriram
{"title":"Successful surgical extraction of an entrapped intra-aortic balloon pump","authors":"Jayarama Pai, S. Mukkannavar, Bharat Siddharth, R. Geethika, D. Shriram","doi":"10.4103/jpcs.jpcs_84_22","DOIUrl":"https://doi.org/10.4103/jpcs.jpcs_84_22","url":null,"abstract":"Intra-aortic balloon pump use is an approach for the provision of mechanical support to improve cardiac output and perfusion in the perioperative period in patients undergoing coronary intervention. Despite its beneficial use, rupture of the balloon and entrapment of blood clots in the lumen may occur in very rare cases. We discuss a postoperative presentation, plan, and operative management for the removal of an entrapped balloon catheter.","PeriodicalId":17503,"journal":{"name":"Journal of the Practice of Cardiovascular Sciences","volume":"9 1","pages":"73 - 75"},"PeriodicalIF":0.1,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"47880046","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"A quasi-experimental study to assess the effectiveness of structured counseling among caregivers of heart failure patients on selected outcomes","authors":"Lakshmanan Gopichandran, Shivani Chauhan, Milan Tirwa, Sandeep Seth, Sujata Satapathy, PayalKahol Hote","doi":"10.4103/jpcs.jpcs_1_23","DOIUrl":"https://doi.org/10.4103/jpcs.jpcs_1_23","url":null,"abstract":"Background: In India, heart failure (HF) is one of the most prevalent chronic diseases. Caregivers are essential and play an important role in bridging the gap in providing care to HF patients. Caregivers' demanding and difficult roles can result in a significant burden, which may lead to stress and symptoms of depression. Aim and Objectives: The objective of the study is to assess the effectiveness of structured counseling on caregiver burden, stress, and depression among caregivers of HF patients. Materials and Methods: Sixty caregivers of patients with HF were selected using consecutive sampling and divided into control and experimental groups. A one-on-one, 30-min structured counseling session was delivered telephonically to caregivers of HF patients. A pretest was taken before the intervention and posttest 1 month later, through telephone, on caregiver burden, stress, and depression using the caregiver burden interview, Perceived Stress Scale, and Patient Health Questionnaire-9. Results: The experimental group showed a significant reduction in caregiver burden (P = 0.001), stress (P = 0.001), and depression (P = 0.001) scores at 1 month. Female caregivers showed a significantly higher caregiver burden (P = 0.046) and depression (P = 0.019), and nuclear families showed a significantly higher caregiver burden (P = 0.016) and depression (P = 0.027). There was a significant positive correlation between stress and the presence of comorbidities (P = 0.021) and depression and the presence of comorbidities (P = 0.042). Conclusions: Structured counseling was effective in reducing caregiver burden and decreasing stress and depression in caregivers of HF patients.","PeriodicalId":17503,"journal":{"name":"Journal of the Practice of Cardiovascular Sciences","volume":"2 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"136217715","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}