Journal of the South African Veterinary Association最新文献

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Equine colic outcomes and prognostic factors at a South African academic hospital (2019-2021). 南非一家学术医院的马绞痛结局和预后因素(2019-2021)。
IF 0.5 4区 农林科学
Journal of the South African Veterinary Association Pub Date : 2025-07-01 Epub Date: 2025-05-20 DOI: 10.36303/JSAVA.672
L M van der Merwe, E C Schliewert
{"title":"Equine colic outcomes and prognostic factors at a South African academic hospital (2019-2021).","authors":"L M van der Merwe, E C Schliewert","doi":"10.36303/JSAVA.672","DOIUrl":"10.36303/JSAVA.672","url":null,"abstract":"<p><strong>Background: </strong>Colic is a common equine emergency requiring medical or surgical intervention. These interventions can be costly, making outcomes data and prognostic indicators essential for guiding referral and treatment decisions.</p><p><strong>Objective: </strong>To determine survival rates to hospital discharge and evaluate prognostic indicators in equine colic cases treated at a referral hospital (Onderstepoort Veterinary Academic Hospital [OVAH], South Africa).</p><p><strong>Methods: </strong>This retrospective observational cohort study analysed records from horses with colic that were presented to the OVAH from January 2019 to August 2021. Data included signalment, admission heart rate (HR) and packed cell volume (PCV), treatment type (medical vs. surgical), surgical diagnosis, postoperative complications, and survival to discharge.</p><p><strong>Results: </strong>Of 415 cases, 375 were treated (292 medically, 83 surgically). 91% of medically, 77% of surgically treated, and 88% overall survived. Compared to a previous study, overall survival to discharge improved by 5% (<i>p</i> = 0.025), mainly due to improved surgical outcomes. Survival was associated with treatment type and surgical lesion site (lower for small intestinal than large intestinal lesions). Medically treated cases with an increased HR and surgical cases with a high PCV had lower survival rates. Signalment showed no association with outcomes.</p><p><strong>Conclusion: </strong>Survival rates to discharge were comparable to previously published international reports and showed significant improvement to previous results from the same institution, due to improved surgical outcomes. These findings can assist veterinarians in referral and treatment decisions. Further research on long-term survival and additional prognostic indicators is required to improve outcome predictions for equine colic treatment.</p>","PeriodicalId":17467,"journal":{"name":"Journal of the South African Veterinary Association","volume":" ","pages":"23-32"},"PeriodicalIF":0.5,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144111377","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The prevalence of OvHV-2 in the smegma, nasal secretions and penile environment of rams (Ovis aries). OvHV-2在公羊包膜、鼻分泌物和阴茎环境中的流行。
IF 0.5 4区 农林科学
Journal of the South African Veterinary Association Pub Date : 2025-07-01 Epub Date: 2025-05-20 DOI: 10.36303/JSAVA.677
L Fernhout, H Lambrechts, J H C van Zyl
{"title":"The prevalence of OvHV-2 in the smegma, nasal secretions and penile environment of rams (<i>Ovis aries</i>).","authors":"L Fernhout, H Lambrechts, J H C van Zyl","doi":"10.36303/JSAVA.677","DOIUrl":"10.36303/JSAVA.677","url":null,"abstract":"<p><p>Ulcerative balanoposthitis (UB) is a venereal disease which has frequently been diagnosed in sheep in South Africa (SA) since 1979, with no conclusive causative agent or treatment available. The purpose of this study was to determine whether ovine herpesvirus 2 (OvHV-2) can be used as biomarker to diagnose the early onset of UB in sheep flocks in SA. The study made use of 10 healthy Dohne Merino rams, two healthy Dorper rams, and 10 UB-affected Dorper rams. Smegma-, blood-, nasal swab- and sheath swab samples, respectively, were collected from all rams, and subjected to a single-tube hemi-nested PCR analysis to determine OvHV-2 status of all the sample types collected. The prevalence of OvHV-2 in all 22 animals was 22.75%, irrespective of breed or health status. The detection rate of OvHV-2 was 33.3% for the 10 UB-positive animals, and 16.7% for the 12 UB-negative animals. In blood, OvHV-2had a 4.54% detection rate, 8.33% in smegma, 13.64% in nasal samples, and a 0% detection in penile swabs. This study found nosignificant co-occurrence of UB and OvHV-2, which indicates that OvHV-2 cannot be considered as a biomarker for the early onset of UB or a causative agent of UB.</p>","PeriodicalId":17467,"journal":{"name":"Journal of the South African Veterinary Association","volume":" ","pages":"18-22"},"PeriodicalIF":0.5,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144110677","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Evaluation of immobilisation using a fixed-dose combination of butorphanol, azaperone, and medetomidine, along with a low dose of ketamine, in chacma baboons (Papio ursinus). 在chacma狒狒(Papio ursinus)中使用布托啡诺、阿扎哌酮和美托咪定的固定剂量组合以及低剂量氯胺酮进行固定的评估。
IF 0.5 4区 农林科学
Journal of the South African Veterinary Association Pub Date : 2025-07-01 Epub Date: 2025-05-20 DOI: 10.36303/JSAVA.674
S Pfitzer, L C Bäckström, J P Raath, A Semjonov, L L Laubscher
{"title":"Evaluation of immobilisation using a fixed-dose combination of butorphanol, azaperone, and medetomidine, along with a low dose of ketamine, in chacma baboons (<i>Papio ursinus</i>).","authors":"S Pfitzer, L C Bäckström, J P Raath, A Semjonov, L L Laubscher","doi":"10.36303/JSAVA.674","DOIUrl":"10.36303/JSAVA.674","url":null,"abstract":"<p><strong>Background: </strong>Current literature most commonly describes the use of the dissociative drug ketamine for the immobilisation of baboons, either on its own or in combination with other drugs such as α-2 agonists or benzodiazepines. Currently, no reversal is available for ketamine, leading to prolonged and often rough recoveries of the animals, especially if high doses of ketamine are used.</p><p><strong>Objectives: </strong>In this study, the fixed-dose combination of butorphanol, azaperone and medetomidine (BAM) with a low dose of ketamine (K-BAM) was evaluated for immobilisation and recovery parameters of chacma baboons.</p><p><strong>Methods: </strong>Fifteen baboons were immobilised and monitored. Actual doses administered: BAM 0.01 ± 0.005 ml/kg (butorphanol 0.31 ± 0.15 mg/kg, azaperone 0.12 ± 0.06 mg/kg, medetomidine 0.12 ± 0.06 mg/kg) and ketamine 2.04 ± 0.22 mg/kg. During immobilisation, heart rate (HR), respiration rate (RR), peripheral oxygen saturation (SpO<sub>2</sub>), end-tidal carbon dioxide (EtCO<sub>2</sub>), noninvasive blood pressure (BP) and blood gases were evaluated.</p><p><strong>Results: </strong>Inductions were reached in 3.46 ± 1.36 minutes. Overall, severe hypoxaemia (SpO<sub>2</sub>: 62 ± 13%; PaO<sub>2</sub>: 37 ± 10 mmHg) was observed in all baboons as well as elevated EtCO<sub>2</sub> (63 ± 9 mmHg) and PaCO<sub>2</sub> (63 ± 9 mmHg) values. Other measured parameters stayed within normal ranges. Recoveries were fully reached at 4.8 ± 2.8 minutes after intramuscular injection of the reversal naltrexone and atipamezole.</p><p><strong>Conclusion: </strong>BAM with a low dose of ketamine produced short-term immobilisation, allowing for minor veterinary procedures. The severe hypoxaemia observed in all animals, however, raises serious concerns regarding the safety of this protocol.</p>","PeriodicalId":17467,"journal":{"name":"Journal of the South African Veterinary Association","volume":" ","pages":"3-7"},"PeriodicalIF":0.5,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144111390","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Factors affecting in vitro oocyte maturation in Southern white rhinoceros (Ceratotherium simum simum). 影响南方白犀牛体外卵母细胞成熟的因素。
IF 0.5 4区 农林科学
Journal of the South African Veterinary Association Pub Date : 2025-07-01 Epub Date: 2025-05-20 DOI: 10.36303/JSAVA.684
M P Smuts, P R de Bruin, G T Fosgate, L Vorster, M de la Rey, C Lichtenberg, C Young, B S Durrant, L C Meyer, D E Holm
{"title":"Factors affecting in vitro oocyte maturation in Southern white rhinoceros (<i>Ceratotherium simum simum</i>).","authors":"M P Smuts, P R de Bruin, G T Fosgate, L Vorster, M de la Rey, C Lichtenberg, C Young, B S Durrant, L C Meyer, D E Holm","doi":"10.36303/JSAVA.684","DOIUrl":"10.36303/JSAVA.684","url":null,"abstract":"<p><strong>Background: </strong>Population numbers of free-roaming rhinoceros are dwindling while natural breeding in captive populations is challenged by sub-optimal fertility. When natural breeding programmes fail and population numbers continue to decline, the use of assisted reproduction technologies (ART) as a conservation tool to save wildlife species from extinction is imperative. Assisted breeding programmes in rhinoceros are challenging and attempts to develop species-specific ART beyond artificial insemination have been limited. This study evaluates various <i>ex</i>- and <i>in-situ</i> factors that could potentially affect in vitro oocyte maturation (IVM) in the Southern white rhinoceros (SWR).</p><p><strong>Objective: </strong>To identify predictors of oocyte maturation following ovum pick-up (OPU) procedures performed on a large number of rhinoceros under different management conditions.</p><p><strong>Methods: </strong>Data from 85 OPU procedures between November 2018 and June 2023 were obtained for this study. A total of 23 factors (three animal, four environmental, 16 laboratory) were evaluated as potentially affecting IVM success.</p><p><strong>Results: </strong>Of the 85 procedures performed on 59 SWR, a total of 265 oocytes were collected with a median of two oocytes (range 0-18) per OPU. Eighteen (18) of the procedures yielded 0 oocytes. The overall maturation rate was 30% (80/265), and six identified factors had significant univariate associations with maturation outcome, of which three remained in the multivariable model.</p><p><strong>Conclusion: </strong>Farming system, season and oocyte density in maturation medium (> 100 ul/oocyte) were independently associated with improved maturation success (<i>p</i> < 0.05).</p>","PeriodicalId":17467,"journal":{"name":"Journal of the South African Veterinary Association","volume":" ","pages":"8-17"},"PeriodicalIF":0.5,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144111392","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Could it have been spirocercosis? 会不会是螺旋体病?
IF 0.5 4区 农林科学
Journal of the South African Veterinary Association Pub Date : 2025-07-01 Epub Date: 2025-05-20 DOI: 10.36303/JSAVA.707
J Schröder
{"title":"Could it have been spirocercosis?","authors":"J Schröder","doi":"10.36303/JSAVA.707","DOIUrl":"10.36303/JSAVA.707","url":null,"abstract":"<p><p>As a newly-minted veterinarian and aspirant pathologist, my first publication reported on an osteosarcoma at the thoracic inlet of a dog (Schröder 1976). The case was noteworthy because it was unusual for an osteosarcoma to originate on the axial skeleton, rather than on one of the long bones. Several years later, now wearing a parasitologist's hat, I have asked myself on numerous occasions if I might have missed an aetiological diagnosis of spirocercosis because I was too fixated on the neoplasm and its location. My only <i>aide memoire</i> is the paper from 1976, according to which I looked for and found metastases in the liver and lungs, but alas, no indication that I had also examined the oesophageal wall carefully.</p>","PeriodicalId":17467,"journal":{"name":"Journal of the South African Veterinary Association","volume":" ","pages":"2"},"PeriodicalIF":0.5,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144111374","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Semi-cylindrical recession trochleoplasty using 3D saw guides for canine patellar luxation. 半圆柱形滑车退行成形术采用三维锯引导犬髌骨脱位。
IF 0.5 4区 农林科学
Journal of the South African Veterinary Association Pub Date : 2025-07-01 DOI: 10.36303/JSAVA.692
S B Park, J Y Baek, S Y Heo
{"title":"Semi-cylindrical recession trochleoplasty using 3D saw guides for canine patellar luxation.","authors":"S B Park, J Y Baek, S Y Heo","doi":"10.36303/JSAVA.692","DOIUrl":"10.36303/JSAVA.692","url":null,"abstract":"<p><p>Medial patellar luxation (MPL) is a common orthopaedic condition in dogs that often requires surgical intervention. Semi-cylindrical recession trochleoplasty (SCRT) is a promising technique; however, the adjustment increments of commercially available SCRT saw guides are limited. As an alternative, the effectiveness of patient-specific 3D-printed saw guides for SCRT was assessed for three small dogs with MPL. An eight-year-old Chihuahua (6 kg) and a ten-year-old Maltese (5 kg) with MPL Grade 3, as well as a fiveyear- old Cocker Spaniel (10 kg) with MPL Grade 4, were included in this study. Preoperative computed tomography (CT) scans confirmed no angular bone deformities in the three dogs. The animals underwent SCRT using 3D-printed patient-specific saw guides, which allowed for customised adjustments to the trochlear groove depth, overcoming the 1.5 mm increment limitation of commercially available guides. Digital imaging and communications in medicine (DICOM) images from the CT scans were converted into stereolithography (STL) files and Fusion 360 was used to design the saw guides, which were then 3D-printed for use with SCRT under general anaesthesia. Postoperative orthopaedic examinations and radiographs performed two weeks after surgery showed that two of the dogs had no pelvic limb lameness or patellar reluxation. One patient did not achieve complete MPL correction, despite the appropriate trochlear groove depth being obtained, due to extrinsic factors. The 3D-printed patient-specific saw guides facilitated precise customisation of the trochlear groove depth during SCRT in the dogs analysed in this study, highlighting the potential to enhance surgical accuracy. Therefore, this approach has the potential to advance MPL treatment by enabling greater surgical precision and addressing challenges associated with operative time and technical difficulty. Further studies with larger sample sizes and standardised protocols are needed to fully assess the clinical benefits and cost-effectiveness of this method.</p>","PeriodicalId":17467,"journal":{"name":"Journal of the South African Veterinary Association","volume":"96 1","pages":"33-36"},"PeriodicalIF":0.5,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147355563","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Application of the Alivecor KardiaMobile smartphone modulated ECG device for use in horses. Alivecor KardiaMobile智能手机调制心电图设备在马身上的应用。
IF 0.9 4区 农林科学
Journal of the South African Veterinary Association Pub Date : 2024-03-01 Epub Date: 2023-06-22 DOI: 10.36303/JSAVA.540
G Piketh, A Williams, E C Schliewert
{"title":"Application of the Alivecor KardiaMobile smartphone modulated ECG device for use in horses.","authors":"G Piketh, A Williams, E C Schliewert","doi":"10.36303/JSAVA.540","DOIUrl":"10.36303/JSAVA.540","url":null,"abstract":"<p><p>Electrocardiography is the method used to monitor the electrical impulses in the heart. These diagnostics are increasingly making use of smartphone-based technologies. The objective of this research was to determine whether the Alivecor KardiaMobile (ECG<sub>AKM</sub>) smartphone-modulated electrocardiographic device, a novel ECG device, can be used to obtain reliable electrocardiogram (ECG) readings in horses. The device was initially tested in 36 Nooitgedacht pony mares to determine the best site of application, method of skin preparation, and ECG<sub>AKM</sub> device orientation for reliable ECG tracings. Once the most reliable site for ECG acquisition was determined, the device was then applied, in this manner, to 31 Nooitgedacht pony mares and compared with a standard telemetric ECG system (ECG<sub>TV</sub>). The ECG<sub>AKM</sub> device was best applied in the fourth intercostal space on the left hemithorax in a vertical orientation and with the skin dampened with 70% ethanol. Mean values determined for RR and QT intervals between the ECG<sub>AKMS</sub> and ECG<sub>TV</sub> were not significantly different, however, mean values for the duration of the QRS complexes were significantly different for the two devices. There is acceptable agreement between the ECG<sub>TV</sub> and ECG<sub>AKM</sub> devices with regards to the measurement of the PQ; RR and QT intervals but not the QRS duration. The automatically calculated heart rate is not an accurate measure of true heart rate. The Alivecor KardiaMobile (ECG<sub>AKM</sub>) device can be considered as a simplified screening ECG device in situations where the more standardised system is either unavailable or impractical, but has some limitations.</p>","PeriodicalId":17467,"journal":{"name":"Journal of the South African Veterinary Association","volume":" ","pages":"20-27"},"PeriodicalIF":0.9,"publicationDate":"2024-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9689771","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Airborne bacteria in veterinary surgical theatres in South Africa. 南非兽医手术室中的空气传播细菌。
IF 0.9 4区 农林科学
Journal of the South African Veterinary Association Pub Date : 2023-09-26 DOI: 10.36303/JSAVA.535
C van der Merwe, V Naidoo
{"title":"Airborne bacteria in veterinary surgical theatres in South Africa.","authors":"C van der Merwe,&nbsp;V Naidoo","doi":"10.36303/JSAVA.535","DOIUrl":"https://doi.org/10.36303/JSAVA.535","url":null,"abstract":"<p><p>The bioaerosol composition of the theatre environment plays a determining role in the development of surgical site infections (SSIs). It has been demonstrated that the concentration of viable airborne bacteria is influenced by the level of room occupancy, utilisation of surgical attire and importantly, proper ventilation systems, which are often lacking in the average veterinary facility. The aim of this study was to evaluate the airborne bacterial load encountered in non-environmentally controlled small animal veterinary theatres during routine surgical sterilisations, and to correlate these findings with the managerial practices at the facility. Four veterinary facilities with differing throughputs and managerial practices were recruited into the study. Blood agar settle plates, open from first incision to last suture, were used to quantify organisms that could settle in an incision. The 45 plates yielded 487 bacterial isolates (53 species). <i>The Micrococcus</i> (28.8%) and <i>Staphylococcus</i> (16.8%) genera were predominant. Of the isolates 61.8% were classified as human/small animal commensals and 37.2% belonged to species previously implicated in small animal SSIs. Specific trends were additionally evident in the bioaerosol loads. High room occupancy, lack of surgical attire and exposure to the outside environment were associated with higher bacterial counts. Accumulation from consecutive procedures was identified and linked to total occupancy time of the room. Current mitigation measures were not ideal to minimise the SSI risk. Routine, frequent and thorough cleaning in combination with surgical attire utilisation is recommended to reduce the bioburden for patient benefit.</p>","PeriodicalId":17467,"journal":{"name":"Journal of the South African Veterinary Association","volume":"94 1","pages":"130-144"},"PeriodicalIF":0.9,"publicationDate":"2023-09-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41136950","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Urethral cutaneous fistula correction using an autologous tunica vaginalis pedicle flap in a four-year-old intact male German shepherd dog. 在一只四岁的完整雄性德国牧羊犬身上使用自体鞘膜蒂瓣修复尿道皮瘘。
IF 0.9 4区 农林科学
Journal of the South African Veterinary Association Pub Date : 2023-09-26 DOI: 10.36303/JSAVA.558
K M van de Wetering, R C Elliott
{"title":"Urethral cutaneous fistula correction using an autologous tunica vaginalis pedicle flap in a four-year-old intact male German shepherd dog.","authors":"K M van de Wetering,&nbsp;R C Elliott","doi":"10.36303/JSAVA.558","DOIUrl":"https://doi.org/10.36303/JSAVA.558","url":null,"abstract":"<p><p>Urethral cutaneous fistulas are rarely reported in dogs. Several techniques have been described to treat urethrocutaneous fistulas with different degrees of success. This case report is on a four-year-old male intact German shepherd diagnosed with urethrocutaneous fistulas after two weeks of dysuria. The urethra was repaired using an autologous tunica vaginalis pedicle flap after open castration and scrotal ablation. The dog was catheterised for two weeks after which a positive contrast urethrogram revealed a healed urethra with no stricture or leakage into surrounding tissue. The dog was discharged the following day after normal urination. Follow-up examination with the referring veterinarian at five months confirmed that the dog was clinically healthy and urinating normally. Literature about urethrocutaneous fistulas is lacking in the small animal field. To our knowledge there are no reports in the literature describing the use of an autologous tunica vaginalis pedicle flap for the repair of a urethral defect in dogs. This case report describes a novel technique to treat urethrocutaneous fistulas in an intact male dog.</p>","PeriodicalId":17467,"journal":{"name":"Journal of the South African Veterinary Association","volume":"94 1","pages":"59-62"},"PeriodicalIF":0.9,"publicationDate":"2023-09-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41124609","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Efficacy and safety of three different opioid-based immobilisation combinations in blesbok (Damaliscus pygargus phillipsi). 三种不同的基于阿片类药物的固定化组合在大白菜中的有效性和安全性。
IF 0.9 4区 农林科学
Journal of the South African Veterinary Association Pub Date : 2023-09-26 DOI: 10.36303/JSAVA.567
A Roug, C Smith, J P Raath, L Cr Meyer, L L Laubscher
{"title":"Efficacy and safety of three different opioid-based immobilisation combinations in blesbok (<i>Damaliscus pygargus phillipsi</i>).","authors":"A Roug,&nbsp;C Smith,&nbsp;J P Raath,&nbsp;L Cr Meyer,&nbsp;L L Laubscher","doi":"10.36303/JSAVA.567","DOIUrl":"https://doi.org/10.36303/JSAVA.567","url":null,"abstract":"<p><p>African wildlife species are increasingly being immobilised with combinations of a low dose of potent opioids combined with medetomidine and azaperone. The physiological effects of these combinations in comparison to conventional potent opioidazaperone combinations have scarcely been evaluated. In this cross-over study conducted on eight captive blesbok, we compared the physiological variables of blesbok immobilised with 2 mg of thiafentanil + 10 mg of azaperone (TA); 0.5 mg thiafentanil + 1.5 mg medetomidine (TM), and 0.5 mg thiafentanil + 1.5. mg medetomidine + 10 mg azaperone (TMA). Thiafentanil's effects were antagonised with naltrexone at 10 mg naltrexone per mg thiafentanil, and the medetomidine effects with atipamezole at 5 mg atipamezole per mg medetomidine. The physiological variables were compared between treatment groups using descriptive statistics and repeated measures ANOVA. The TA combination resulted in the shortest induction and recovery times, higher heart rates, respiratory rates, PaO<sub>2</sub>, SpO<sub>2</sub>, and lower MAP and A-a gradients, but with less muscle relaxation. The TM and TMA combinations caused marked bradycardia and hypoxaemia. The hypoxaemia was most severe in animals immobilised with TMA, and four of eight blesbok immobilised had a PaO<sub>2</sub> < 35 mmHg at the 10- or 15-minute sampling point. These blesbok were provided supplementary oxygen, which corrected the hypoxaemia. The TA combinations caused the lowest degree of physiological compromise. All three combinations were effective for the immobilisation of blesbok, but as the low-dose thiafentanil and high-dose medetomidine combinations caused marked hypoxaemia, supplementary oxygen is recommended when using these combinations.</p>","PeriodicalId":17467,"journal":{"name":"Journal of the South African Veterinary Association","volume":"94 1","pages":"123-129"},"PeriodicalIF":0.9,"publicationDate":"2023-09-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41148966","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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