Journal of Traditional and Complementary Medicine最新文献

{"title":"Clinical Effects of Acupuncture Treatment for Prevention of Insomnia-induced Stroke: A Large-Scale Cohort Study","authors":"Cheng-Hao Huang, Shun-Ku Lin, Heng-Jun Lin, Yu-Tung Hung, Tzu-Ju Hsu, Fuu-Jen Tsai, Ching-Liang Hsieh","doi":"10.1016/j.jtcme.2024.07.003","DOIUrl":"https://doi.org/10.1016/j.jtcme.2024.07.003","url":null,"abstract":"","PeriodicalId":17449,"journal":{"name":"Journal of Traditional and Complementary Medicine","volume":null,"pages":null},"PeriodicalIF":3.3,"publicationDate":"2024-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141692631","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Xinbao Pill Attenuated Water Retention by Regulating the CaSR/AQP2 Pathway in LAD-induced Chronic Heart Failure Rats","authors":"Shiqi Li, Yuanping Wang, Xulan Cui, Xiaoyu Tian, Ziwei Huang, Rong Zhang, Yuanyuan Cheng, Zhongqiu Liu, Dawei Wang","doi":"10.1016/j.jtcme.2024.07.002","DOIUrl":"https://doi.org/10.1016/j.jtcme.2024.07.002","url":null,"abstract":"","PeriodicalId":17449,"journal":{"name":"Journal of Traditional and Complementary Medicine","volume":null,"pages":null},"PeriodicalIF":3.3,"publicationDate":"2024-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141704016","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The therapeutic effect and metabolic mechanism analysis of Guilingji on idiopathic oligo-asthenoteratozoospermia","authors":"Yuming Feng ,&nbsp;Shanmeizi Zhao ,&nbsp;Rong Ju ,&nbsp;Jianbo Li ,&nbsp;Chengshuang Pan ,&nbsp;Qinglai Tang ,&nbsp;Zhichuan Zou ,&nbsp;Jun Jing ,&nbsp;Yao Xu ,&nbsp;Hualong Ding ,&nbsp;Jinzhao Ma ,&nbsp;Zhou Li ,&nbsp;Ting Tang ,&nbsp;Yong Shao ,&nbsp;Li Chen ,&nbsp;Xuefeng Huang ,&nbsp;Xiaohong Wang ,&nbsp;Bing Yao","doi":"10.1016/j.jtcme.2024.01.001","DOIUrl":"10.1016/j.jtcme.2024.01.001","url":null,"abstract":"<div><h3>Introduction</h3><p>Guilingji, a famous traditional Chinese medicine (TCM) formula, has been used to combat aging and male sexual dysfunction in China for centuries. To date, there has been little evidence-based clinical research on the use of Guilingji to treat idiopathic oligo-asthenoteratozoospermia (OAT), and the therapeutic mechanism from a metabolic perspective needs to be investigated further.</p></div><div><h3>Methods</h3><p>This was a multicenter, double-blind, randomized controlled clinical study of 240 patients with idiopathic OAT recruited from four hospitals between January 2020 and January 2022. Patients were randomly assigned in a 1꞉1 ratio to receive oral Guilingji capsules or placebo for 12 weeks. The total progressive motile sperm count (TPMSC) was considered the primary outcome, and the other sperm parameters, seminal plasma parameters and serum hormones were considered the secondary outcome. A nontargeted metabolomics analysis of serum from OAT patients before and after Guilingji administration was performed by HPLC–MS to identify key metabolites. Furthermore, we used a rat model to show spermatogenesis phenotypes to validate the effect of the key metabolites screened from the patients.</p></div><div><h3>Results</h3><p>At weeks 4, 8 and 12, TPMSC and other sperm parameters were significantly improved in the Guilingji group compared with the placebo group (<em>P</em> &lt; 0.05 for all comparisons). At week 4, superoxide dismutase (SOD) and acrosomal enzyme activity of seminal plasma were significantly elevated in the Guilingji group compared with the placebo group, while reactive oxygen species (ROS) levels were significantly reduced (<em>P</em> &lt; 0.05). Lactate dehydrogenase-X (LDHX) levels appeared to be significantly increased after 12 weeks continuous medication compared with Placebo group (<em>P</em> = 0.032). The metabolomics analysis of serum from OAT patients before and after Guilingji administration showed that the glucose-6-phosphate (G6P) concentration in patients' serum was significantly elevated after Guilingji treatment. Compared to the control, when Kidney-Yang deficiency model rats were treated with Guilingji or its key intermediate metabolite G6P, their sperm concentration and spermatozoic activity were improved similarly, and their structural damage of rat's testicular and epididymal tissues were recovered.</p></div><div><h3>Conclusion</h3><p>This study provided valuable clinical evidence for the utility of Guilingji as a treatment for OAT. These findings thus demonstrate that G6P is involved in the therapeutic mechanism of Guilingji in OAT treatment based on clinical and rat intervention studies.</p></div>","PeriodicalId":17449,"journal":{"name":"Journal of Traditional and Complementary Medicine","volume":null,"pages":null},"PeriodicalIF":3.3,"publicationDate":"2024-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2225411024000014/pdfft?md5=1beea949ce36b7b4c117aec01a97eabc&pid=1-s2.0-S2225411024000014-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139391853","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Network pharmacology approach and experimental verification of earthworm protein in the treatment of diabetes mellitus-induced erectile dysfunction","authors":"Liming Liu, Yuanfeng Zhang, Aiping Zhang, Rui Yan, Xiaowei Ji, Jiashu Yang, Xinping Wang, Yongze Gao, Xiping Xing","doi":"10.1016/j.jtcme.2024.06.002","DOIUrl":"https://doi.org/10.1016/j.jtcme.2024.06.002","url":null,"abstract":"","PeriodicalId":17449,"journal":{"name":"Journal of Traditional and Complementary Medicine","volume":null,"pages":null},"PeriodicalIF":4.5,"publicationDate":"2024-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141400215","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Crocin elicits potent anti-inflammatory and fibrinolytic properties post tendon injury, A new molecule for adhesion therapy","authors":"Hamideh Naimi, Majid Khazaei, Fariba Sharifnia, S. M. Hassanian, Sayyed-Hadi Sayyed-Hosseinian","doi":"10.1016/j.jtcme.2024.06.001","DOIUrl":"https://doi.org/10.1016/j.jtcme.2024.06.001","url":null,"abstract":"","PeriodicalId":17449,"journal":{"name":"Journal of Traditional and Complementary Medicine","volume":null,"pages":null},"PeriodicalIF":4.5,"publicationDate":"2024-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141407677","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Integrated serum pharmacochemistry and network pharmacology to reveal the kernel material basis and underlying mechanisms of the Fuzi-Lizhong pill for ulcerative colitis","authors":"Huang You, Xia Lin, Qiuhong Wu, XunJian Wu, Shasha Yang, Yidian Dong, Chaomei Fu, Wei Lin, Zhen Zhang","doi":"10.1016/j.jtcme.2024.06.003","DOIUrl":"https://doi.org/10.1016/j.jtcme.2024.06.003","url":null,"abstract":"","PeriodicalId":17449,"journal":{"name":"Journal of Traditional and Complementary Medicine","volume":null,"pages":null},"PeriodicalIF":4.5,"publicationDate":"2024-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141392959","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Himatanthus bracteatus stem bark ethanolic extract obtained by sequential pressurized liquid extraction: chromatographic characterization and profiling of cytotoxic, antitumoral and immunopharmacological properties","authors":"R. Pereira-Filho, Wilson D. Gonçalves‐Júnior, Agenor G. dos Santos-Neto, J.L.S. Cunha, Oslei P. de Almeida, Luciana N. Andrade, Daniela Droppa-Almeida, Ricardo G. Amaral, Cláudio Dariva, J. Cardoso, Patrícia Severino, Eliana B. Souto, R. D. de Albuquerque-Júnior","doi":"10.1016/j.jtcme.2024.06.004","DOIUrl":"https://doi.org/10.1016/j.jtcme.2024.06.004","url":null,"abstract":"","PeriodicalId":17449,"journal":{"name":"Journal of Traditional and Complementary Medicine","volume":null,"pages":null},"PeriodicalIF":4.5,"publicationDate":"2024-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141397265","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Potent anti-biofilm properties of plumbagin against fluconazole-resistant Candida auris","authors":"Hye-Won Jin, Yong-Bin Eom","doi":"10.1016/j.jtcme.2024.06.005","DOIUrl":"https://doi.org/10.1016/j.jtcme.2024.06.005","url":null,"abstract":"","PeriodicalId":17449,"journal":{"name":"Journal of Traditional and Complementary Medicine","volume":null,"pages":null},"PeriodicalIF":4.5,"publicationDate":"2024-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141403823","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Kerala Ayurveda Ostoact Tablet Treats Osteoporosis in Ovariectomized Rat Model Via Regulating RANKL/OPG Pathway","authors":"Deepa Mandlik, Rutuja Patil, Arulmozhi S, Satish Mandlik","doi":"10.1016/j.jtcme.2024.06.007","DOIUrl":"https://doi.org/10.1016/j.jtcme.2024.06.007","url":null,"abstract":"","PeriodicalId":17449,"journal":{"name":"Journal of Traditional and Complementary Medicine","volume":null,"pages":null},"PeriodicalIF":4.5,"publicationDate":"2024-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141407304","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Astragalus mongholicus Polysaccharides Alleviate Insulin Resistance through Modulation of PI3K/AKT, TLR4/NF-kB Signaling Pathway and Microbiota in Rats with Type 2 Diabetes Mellitus","authors":"Haisheng Yuan, Guoquan Xu, Jingran Liu, Yan Yan, Shimin Zhao, Fujuan Cai, Xiuling Yu, Yuzhen Wang, Minhui Li","doi":"10.1016/j.jtcme.2024.05.007","DOIUrl":"https://doi.org/10.1016/j.jtcme.2024.05.007","url":null,"abstract":"","PeriodicalId":17449,"journal":{"name":"Journal of Traditional and Complementary Medicine","volume":null,"pages":null},"PeriodicalIF":4.5,"publicationDate":"2024-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141138041","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}