Journal of the International Association of Providers of AIDS Care最新文献

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This is Your Moment (TiYM): Planning for Implementation of a Novel Media Campaign to Mitigate Intersectional Stigma Among Black Sexual Minority Men Living With HIV in Atlanta, Georgia. 这是你的时刻(TiYM):计划实施一项新的媒体运动,以减轻在亚特兰大,乔治亚州感染艾滋病毒的黑人性少数男性的交叉耻辱。
IF 2.1
Journal of the International Association of Providers of AIDS Care Pub Date : 2026-01-01 Epub Date: 2026-07-31 DOI: 10.1177/23259582261475546
Madeleine H Goldstein, Tigest F Mekonnen, Rosalind N Byrd, Alphonso Mills, Madeline Lynam, Romell Phillips, Antonio Newman, Christian Dacus, Kate Winskell, Rhonda Holliday, Sophia A Hussen
{"title":"This is Your Moment (TiYM): Planning for Implementation of a Novel Media Campaign to Mitigate Intersectional Stigma Among Black Sexual Minority Men Living With HIV in Atlanta, Georgia.","authors":"Madeleine H Goldstein, Tigest F Mekonnen, Rosalind N Byrd, Alphonso Mills, Madeline Lynam, Romell Phillips, Antonio Newman, Christian Dacus, Kate Winskell, Rhonda Holliday, Sophia A Hussen","doi":"10.1177/23259582261475546","DOIUrl":"10.1177/23259582261475546","url":null,"abstract":"<p><p>ObjectiveBlack sexual minority men (SMM) in the United States experience disproportionate HIV burden and lower engagement across the HIV Continuum of Care (HIV-CoC), partly due to intersecting stigmas. Structural interventions addressing these barriers remain limited.MethodsWe developed <i>This is Your Moment</i> (TiYM), a culturally-grounded media campaign designed to mitigate stigma and encourage engagement in care for Black SMM in Atlanta, Georgia. To inform implementation, we conducted focus groups with 63 stakeholders from six clinics and community-based organizations (March-October 2023), guided by the Consolidated Framework for Implementation Research. Transcripts were analyzed thematically.ResultsParticipants described TiYM as highly acceptable, engaging, and relatable. Facilitators included alignment with organization priorities; ease of QR code integration; potential to improve health literacy and reduce stigma. Barriers included concerns about inclusivity and unintended disclosure.ConclusionKey partners perceived TiYM as having strong implementation potential, while identifying barriers for refinement and implementation strategy.</p>","PeriodicalId":17328,"journal":{"name":"Journal of the International Association of Providers of AIDS Care","volume":"25 ","pages":"23259582261475546"},"PeriodicalIF":2.1,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13428153/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148648803","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Evaluating ChatGPT Responses to HIV-Related Patient Questions: Opportunities and Limitations for Patient Counselling. 评估ChatGPT对hiv相关患者问题的回应:患者咨询的机会和限制。
IF 2.1
Journal of the International Association of Providers of AIDS Care Pub Date : 2026-01-01 Epub Date: 2026-08-28 DOI: 10.1177/23259582261485738
Chetan Chandrashekar
{"title":"Evaluating ChatGPT Responses to HIV-Related Patient Questions: Opportunities and Limitations for Patient Counselling.","authors":"Chetan Chandrashekar","doi":"10.1177/23259582261485738","DOIUrl":"10.1177/23259582261485738","url":null,"abstract":"<p><p>The use of Artificial Intelligence (AI) technologies such as ChatGPT in patient healthcare-seeking behaviour raises important questions about their role in HIV counselling. This letter presents an <b>exploratory qualitative evaluation</b> of ten commonly asked HIV-related patient questions posed to ChatGPT (GPT-4, OpenAI), with responses recorded verbatim and evaluated for depth, clinical nuance, and appropriateness. While responses were largely accurate, they lacked counselling depth and clinical nuance required for individualised patient counselling. These platforms offer accessibility and anonymity, which may benefit people living with HIV seeking sensitive information. However, overreliance on AI-generated responses poses risks of misinformation. The safe and effective incorporation of ChatGPT into HIV counselling practice requires a collaborative approach with physicians, AI developers, and regulatory bodies.</p>","PeriodicalId":17328,"journal":{"name":"Journal of the International Association of Providers of AIDS Care","volume":"25 ","pages":"23259582261485738"},"PeriodicalIF":2.1,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13525280/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148851002","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
"I Want to Live: A Qualitative Investigation of Barriers and Facilitators to ART Adherence & Mental Health Maintenance in People With HIV". “我想活下去:对艾滋病毒感染者坚持抗逆转录病毒治疗和精神健康维持的障碍和促进因素的定性调查”。
IF 2.1
Journal of the International Association of Providers of AIDS Care Pub Date : 2026-01-01 Epub Date: 2026-01-20 DOI: 10.1177/23259582251413665
Emilie Egger, Pranav Kancherla, Yiqin Zhu, Henna Budhwani, Cecile Denis, Chelsea D Voytek, Lily Brown
{"title":"\"I Want to Live: A Qualitative Investigation of Barriers and Facilitators to ART Adherence & Mental Health Maintenance in People With HIV\".","authors":"Emilie Egger, Pranav Kancherla, Yiqin Zhu, Henna Budhwani, Cecile Denis, Chelsea D Voytek, Lily Brown","doi":"10.1177/23259582251413665","DOIUrl":"10.1177/23259582251413665","url":null,"abstract":"<p><p>ObjectiveMental health symptoms hinder engagement in antiretroviral therapy (ART) adherence among persons with HIV (PWH). Existing information on barriers and facilitators to mental health treatment in PWH is limited. This qualitative study explored barriers and facilitators to mental health treatment and ART adherence in PWH.MethodsPWH (<i>n</i> = 16) and health professionals (<i>N</i> = 6) completed semi-structured interviews.ResultsThree themes describe how and why barriers to care intersected: (1) health systems were not equipped to accommodate the unique needs of people with HIV who needed mental health treatment; (2) complex mental health challenges intersected with other barriers; (3) a stable home base and community were critical to health but difficult to maintain.ConclusionSeveral participants suggested integrating mental health and HIV care.</p>","PeriodicalId":17328,"journal":{"name":"Journal of the International Association of Providers of AIDS Care","volume":"25 ","pages":"23259582251413665"},"PeriodicalIF":2.1,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12819976/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146010968","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Staff Perspectives on Implementation of Long-Acting Injectable Preexposure Prophylaxis at a Low-Barrier Syringe Services Program in Philadelphia, PA. 工作人员对在费城低屏障注射器服务项目中实施长效注射暴露前预防的看法。
IF 2.1
Journal of the International Association of Providers of AIDS Care Pub Date : 2026-01-01 Epub Date: 2026-02-11 DOI: 10.1177/23259582261420655
Marina Plesons, Elana Forman, Erin C McDowell, Douglas Krakower, K Rivet Amico, Allison K Groves, Alexis Roth, Tyler S Bartholomew
{"title":"Staff Perspectives on Implementation of Long-Acting Injectable Preexposure Prophylaxis at a Low-Barrier Syringe Services Program in Philadelphia, PA.","authors":"Marina Plesons, Elana Forman, Erin C McDowell, Douglas Krakower, K Rivet Amico, Allison K Groves, Alexis Roth, Tyler S Bartholomew","doi":"10.1177/23259582261420655","DOIUrl":"10.1177/23259582261420655","url":null,"abstract":"<p><p>IntroductionLong-acting injectable cabotegravir (CAB-LA) for preexposure prophylaxis (PrEP) is a promising HIV prevention tool for people who inject drugs (PWID), who face elevated HIV risk and barriers to care. While acceptable to PWID, CAB-LA implementation in low-barrier syringe services programs (SSPs) has not been examined.MethodsFrom August 2023 to July 2025, we conducted semistructured interviews with 12 SSP staff involved in CAB-LA delivery. Interviews were transcribed and analyzed using thematic analysis guided by the Consolidated Framework for Implementation Research.ResultsFacilitators included CAB-LA's relative advantage over oral PrEP, external technical support, 340B pharmacy revenue, alignment with SSP mission and workflows, motivated staff, and financial incentives. Barriers included lack of FDA approval for PWID, complex logistics, performance pressures, infrastructure constraints, competing priorities, staff workload, and client outreach and engagement.ConclusionIntegrating CAB-LA into SSPs is promising, but successful implementation requires targeted strategies, including additional resources, workflow adaptations, and enhanced outreach.</p>","PeriodicalId":17328,"journal":{"name":"Journal of the International Association of Providers of AIDS Care","volume":"25 ","pages":"23259582261420655"},"PeriodicalIF":2.1,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12907482/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146165591","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Longitudinal Implementation of a Neurodevelopmental Screening Program for Children Born to Mothers Living With HIV in Maternal-Child Clinics in Kenya: A Mixed Methods Study. 肯尼亚母婴诊所对携带艾滋病毒的母亲所生儿童的神经发育筛查项目的纵向实施:一项混合方法研究。
IF 2.1
Journal of the International Association of Providers of AIDS Care Pub Date : 2026-01-01 Epub Date: 2026-01-08 DOI: 10.1177/23259582251407359
Megan S McHenry, Eren Oyungu, Amina Abubakar, Ananda Roselyne Ombitsa, Micaela Gaviola, Cleophas Cherop, Beatrice Kaniaru, Carolyne Jerop, Alan McGuire, Rachel C Vreeman
{"title":"Longitudinal Implementation of a Neurodevelopmental Screening Program for Children Born to Mothers Living With HIV in Maternal-Child Clinics in Kenya: A Mixed Methods Study.","authors":"Megan S McHenry, Eren Oyungu, Amina Abubakar, Ananda Roselyne Ombitsa, Micaela Gaviola, Cleophas Cherop, Beatrice Kaniaru, Carolyne Jerop, Alan McGuire, Rachel C Vreeman","doi":"10.1177/23259582251407359","DOIUrl":"10.1177/23259582251407359","url":null,"abstract":"<p><p>BackgroundChildren with perinatal HIV exposure are at increased risk for neurodevelopmental (ND) delays, yet little is known about ND screening implementation for this population.MethodsThis longitudinal study evaluated ND screening implementation at a health clinic in Kenya, from 9/2021 to 8/2023. Children aged 18-36 months with perinatal HIV exposure were screened using a 12-item general ND tool. Implementation outcomes-acceptability, feasibility, fidelity, and sustainability-were assessed through time-motion observations, clinic records, and semi-structured interviews with caregivers and staff.ResultsOf 507 eligible children, 405 (80%) were screened. Screening rates were consistent over 24 months, with average time reduced to under 5 min. Facilitators included staff collaboration and caregiver support; barriers included time constraints and child temperament.ConclusionsND screening was acceptable, feasible, and sustainable. Policymakers should embed ND screening within national child health programs, invest in workforce training and task-sharing models, strengthen referral and follow-up systems, and ensure affordable access to services.</p>","PeriodicalId":17328,"journal":{"name":"Journal of the International Association of Providers of AIDS Care","volume":"25 ","pages":"23259582251407359"},"PeriodicalIF":2.1,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12783559/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145934214","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Undernutrition and Associated Factors Among Adults on Second-Line Antiretroviral Therapy in Debark, Ethiopia: A Cross-Sectional Study. 在埃塞俄比亚德巴克接受二线抗逆转录病毒治疗的成年人中营养不良及其相关因素:一项横断面研究。
IF 2.1
Journal of the International Association of Providers of AIDS Care Pub Date : 2026-01-01 Epub Date: 2026-03-09 DOI: 10.1177/23259582261432458
Worku Chekol Tassew, Agerie Mengistie Zeleke, Yeshiwas Ayale Ferede, Adane Nigusie Weldeab, Girum Meseret Ayenew
{"title":"Undernutrition and Associated Factors Among Adults on Second-Line Antiretroviral Therapy in Debark, Ethiopia: A Cross-Sectional Study.","authors":"Worku Chekol Tassew, Agerie Mengistie Zeleke, Yeshiwas Ayale Ferede, Adane Nigusie Weldeab, Girum Meseret Ayenew","doi":"10.1177/23259582261432458","DOIUrl":"10.1177/23259582261432458","url":null,"abstract":"<p><p>Background/ObjectivesUndernutrition remains a major public health challenge among people living with HIV, particularly in low-income settings, where it adversely affects treatment outcomes, immunity, and survival, where it contributes to poor treatment outcomes, increased susceptibility to opportunistic infections, and higher mortality. Although several studies in Ethiopia have examined undernutrition among adults receiving first-line antiretroviral therapy (ART), evidence focusing specifically on individuals receiving second-line ART is limited. Therefore, this study aimed to assess the prevalence of undernutrition and identify factors associated with undernutrition among adults living with HIV receiving second-line ART in public health facilities of Debark town, Ethiopia.MethodsAn institution-based cross-sectional study was conducted from June 1 to June 30, 2025, among adults living with HIV receiving second-line ART in public health facilities of Debark town, Ethiopia. Participants were selected using a simple random sampling technique based on medical registration numbers. Data were collected using a structured interviewer-administered questionnaire and medical record review checklist adapted from previous studies. Nutritional status was assessed using body mass index (BMI). Data were entered into EpiData version 3.1 and analyzed using STATA version 14. Bivariable and multivariable logistic regression analyses were performed to identify factors associated with undernutrition.ResultsUndernutrition, defined as a BMI of < 18.5 kg/m<sup>2</sup>, was observed in 24% of the participants (95% confidence interval (CI) [20-28]). Factors significantly associated with undernutrition included poor ART adherence (adjusted odds ratio (AOR) = 4.10; 95% CI [1.64-10.27]), ART duration ≤24 months (AOR = 9.20; 95% CI [3.43-24.65]), presence of opportunistic infections (AOR = 2.35; 95% CI [1.11-4.96]), low dietary diversity score (AOR = 2.19; 95% CI [1.19-4.04]), moderate household food insecurity (AOR = 2.17; 95% CI [1.16-4.09]), and severe household food insecurity (AOR = 2.53; 95% CI [1.17-5.46]).Conclusion and recommendationsThe prevalence of undernutrition among adults receiving second-line ART was high. Poor treatment adherence, opportunistic infections, shorter duration of therapy, household food insecurity, and low dietary diversity were significantly associated with undernutrition. Strengthening nutritional counseling, promoting dietary diversification, linking food-insecure households to food support and social protection programs, and integrating routine nutritional assessment and support into HIV care are recommended to improve nutritional outcomes in this population.</p>","PeriodicalId":17328,"journal":{"name":"Journal of the International Association of Providers of AIDS Care","volume":"25 ","pages":"23259582261432458"},"PeriodicalIF":2.1,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12972545/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147377909","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Incidence and Predictors of Virologic Failure Among Children on First-Line Antiretroviral Therapy in Northwest Ethiopia: A Multicenter Retrospective Follow-Up Study. 埃塞俄比亚西北部一线抗逆转录病毒治疗儿童病毒学失败的发生率和预测因素:一项多中心回顾性随访研究。
IF 2.1
Journal of the International Association of Providers of AIDS Care Pub Date : 2026-01-01 Epub Date: 2026-05-02 DOI: 10.1177/23259582261447448
Zemene Mesafint Kassie, Nebiyu Mekonnen Derseh, Tadesse Awoke Ayele, Meron Asmamaw Alemayehu, Agerie Mengistie Zeleke, Yeshiwas Ayale Ferede, Worku Chekol Tassew, Jember Ayelgne Beyene
{"title":"Incidence and Predictors of Virologic Failure Among Children on First-Line Antiretroviral Therapy in Northwest Ethiopia: A Multicenter Retrospective Follow-Up Study.","authors":"Zemene Mesafint Kassie, Nebiyu Mekonnen Derseh, Tadesse Awoke Ayele, Meron Asmamaw Alemayehu, Agerie Mengistie Zeleke, Yeshiwas Ayale Ferede, Worku Chekol Tassew, Jember Ayelgne Beyene","doi":"10.1177/23259582261447448","DOIUrl":"10.1177/23259582261447448","url":null,"abstract":"<p><p>BackgroundVirologic failure in children is a significant public health concern in sub-Saharan Africa. This study aims to assess the incidence rate of virologic failure and its predictors among children undergoing first-line antiretroviral therapy (ART) in Ethiopia.MethodsA multicenter retrospective follow-up study was conducted in HIV-infected children on first-line ART from January 1, 2013, to December 31, 2022, in Ethiopia. A simple random sampling method was employed to select the sample. Data entry was performed using EpiData, and analysis was conducted using STATA version 14. Kaplan-Meier curves and log-rank tests were utilized for survival analysis.ResultAmong 537 HIV-infected children followed over the study period, 12.29% developed virologic failure, yielding an incidence rate of 17 per 10 000 person-month observations (95% confidence interval [CI]: 13.4, 21.7). Factors independently associated with an increased risk of virologic failure included poor ART adherence (adjusted hazard ratio [AHR] = 2.63; 95% CI: 1.38, 4.97), advanced World Health Organization (WHO) Treatment (T) stages III and IV (AHR = 2.71; 95% CI: 1.15, 6.37), no history of regimen change (AHR = 5.88; 95% CI: 3.23, 10.71), and age at ART initiation above 10 years (AHR = 2.97; 95% CI: 1.30, 6.78). In contrast, having a caregiver younger than 40 years was associated with a significantly lower risk of virologic failure (AHR = 0.42; 95% CI: 0.25, 0.72). These findings emphasize the importance of monitoring adherence, providing closer follow-up for children in advanced treatment stages, and considering caregiver-related factors to reduce virologic failure.ConclusionsVirologic failure among HIV-infected children on first-line ART in Northwest Ethiopia was a relatively low incidence. Interventions targeting poor adherence, children with advanced WHO Treatment (T) stage, older age at ART initiation, and those with no history of regimen change are essential. Additionally, caregiver characteristics, such as age below 40 years, play a protective role and should be considered when designing adherence support and monitoring strategies to further reduce the risk of virologic failure.</p>","PeriodicalId":17328,"journal":{"name":"Journal of the International Association of Providers of AIDS Care","volume":"25 ","pages":"23259582261447448"},"PeriodicalIF":2.1,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13153529/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147816808","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Global, Regional, and National Burden of HIV and Drug-Susceptible Tuberculosis Co-Infection Among Adolescents and Young Adults (1990-2021). 青少年和年轻人中艾滋病毒和药物敏感结核病合并感染的全球、区域和国家负担(1990-2021)
IF 2.1
Journal of the International Association of Providers of AIDS Care Pub Date : 2026-01-01 Epub Date: 2026-05-15 DOI: 10.1177/23259582261449285
Junhui Wu, Guangqi Han, Disha Zhu, Weixuan Wang, Shaomei Shang
{"title":"Global, Regional, and National Burden of HIV and Drug-Susceptible Tuberculosis Co-Infection Among Adolescents and Young Adults (1990-2021).","authors":"Junhui Wu, Guangqi Han, Disha Zhu, Weixuan Wang, Shaomei Shang","doi":"10.1177/23259582261449285","DOIUrl":"10.1177/23259582261449285","url":null,"abstract":"<p><p>BackgroundHIV and drug-susceptible tuberculosis (DS-TB) co-infection severely affects adolescents and young adults (10-24 years), leading to a significant infectious disease burden, yet this age group remains overlooked. This study assessed the 1990-2021 global, regional, and national disease burden of HIV and DS-TB co-infection with a specific focus on adolescents and young adults (10-24 years).MethodsThe Global Burden of Diseases, Injuries, and Risk Factors Study 2021 (GBD 2021) estimates disaggregated by HIV status and TB drug susceptibility. Number and rates of the incidence, prevalence, and mortality of HIV and DS-TB co-infection from 1990 to 2021 at the global, regional, and national level among individuals aged 10-24 years were collected from GBD 2021. Trends were analyzed by sex and Sociodemographic Index (SDI).ResultsIn 2021, over 100 000 new cases and nearly 20 000 deaths were recorded globally, with the highest burden in low-SDI regions and Southern Africa. Globally, all metrics initially increased, then declined after reaching their peak. Higher disease burden occurred in females than in males.ConclusionHIV and DS-TB co-infection remains a critical public health challenge for adolescents and young adults. Greater attention must be directed to prevention, treatment, and care among adolescents and young adults.</p>","PeriodicalId":17328,"journal":{"name":"Journal of the International Association of Providers of AIDS Care","volume":"25 ","pages":"23259582261449285"},"PeriodicalIF":2.1,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13180206/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147948728","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Breastfeeding in Women Living With HIV in the ART Era: Toward Risk-Adapted Clinical Care. 抗逆转录病毒时代艾滋病毒感染妇女的母乳喂养:走向适应风险的临床护理。
IF 2.1
Journal of the International Association of Providers of AIDS Care Pub Date : 2026-01-01 Epub Date: 2026-07-21 DOI: 10.1177/23259582261471868
Akel Azzi, Nassar El Assaad, Francois Haddad, Joe Lebbos, Jacques Choucair
{"title":"Breastfeeding in Women Living With HIV in the ART Era: Toward Risk-Adapted Clinical Care.","authors":"Akel Azzi, Nassar El Assaad, Francois Haddad, Joe Lebbos, Jacques Choucair","doi":"10.1177/23259582261471868","DOIUrl":"10.1177/23259582261471868","url":null,"abstract":"<p><p>IntroductionBreastfeeding in women living with HIV remains controversial despite effective antiretroviral therapy (ART), as a small residual transmission risk persists even with viral suppression, leading to divergent global recommendations.MethodsWe performed a narrative review and policy analysis of randomized trials, international guidelines, and national recommendations (2010-2025), focusing on breastfeeding policies, maternal ART, infant prophylaxis, and monitoring strategies across settings.ResultsEvidence from resource-limited settings shows maternal ART during breastfeeding reduces transmission and improves HIV-free survival, supporting WHO recommendations for breastfeeding with ART and infant prophylaxis. In high-income countries, breastfeeding is often discouraged due to safe alternatives, though some guidelines now allow it under strict viral suppression and close monitoring. Observational studies suggest transmission is rare when suppression is maintained.ConclusionsDifferences in guidance mainly reflect risk tolerance and ethics rather than evidence. Breastfeeding may be considered a conditional option within structured clinical pathways.</p>","PeriodicalId":17328,"journal":{"name":"Journal of the International Association of Providers of AIDS Care","volume":"25 ","pages":"23259582261471868"},"PeriodicalIF":2.1,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13389193/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148536347","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Tuberculosis Among Men Who Have Sex With Men Living With HIV in Israel: A Retrospective Nationwide Cohort Study, 2000-2025. 2000-2025年以色列与HIV感染者发生性行为的男性患结核病:一项回顾性全国队列研究
IF 2.1
Journal of the International Association of Providers of AIDS Care Pub Date : 2026-01-01 Epub Date: 2026-09-03 DOI: 10.1177/23259582261478436
Zohar Mor, Tali Wagner, Sivan H Perl
{"title":"Tuberculosis Among Men Who Have Sex With Men Living With HIV in Israel: A Retrospective Nationwide Cohort Study, 2000-2025.","authors":"Zohar Mor, Tali Wagner, Sivan H Perl","doi":"10.1177/23259582261478436","DOIUrl":"10.1177/23259582261478436","url":null,"abstract":"<p><p>ObjectivesThis study compared men who have sex with men (MSM) who lived with HIV (LWHIV) and tuberculosis to MSM LWHIV without tuberculosis and estimated tuberculosis incidence among MSM-LWHIV over 25-years.MethodsData from the Israeli national tuberculosis and HIV registries between 2000 and 2025 were cross-matched by patients' identifiers to compare MSM LWHIV and tuberculosis to other MSM LWHIV older than 15 years. They were followed up from HIV-diagnosis until they developed TB, died, left Israel or end-2025.ResultsOf 3,018 MSM LWHIV who were followed-up for 30,617 person-years, 16 (0.5%) developed tuberculosis, compared with 244 (6.6%) non-MSM LWHIV, corresponding to 5 and 70 cases per 10,000 person-years, respectively (P<0.01). MSM LWHIV and tuberculosis were more commonly non-Israeli born, had lower CD4-counts and not been treated with antiretroviral therapy than MSM LWHIV without tuberculosis.Tuberculosis in MSM was diagnosed within a median of 2.4 years after HIV (range 0-10), and 8 (50.0%) were diagnosed concomitantly with HIV and tuberculosis. Contact tracing revealed one household exposure, while nine (52.9%) probably acquired tuberculosis while originating/visiting high-tuberculosis settings.ConclusionsTuberculosis incidence among MSM LWHIV is very low. Tuberculosis was probably acquired while originating/visiting endemic countries. Routine HIV-testing of patients with tuberculosis is recommended.</p>","PeriodicalId":17328,"journal":{"name":"Journal of the International Association of Providers of AIDS Care","volume":"25 ","pages":"23259582261478436"},"PeriodicalIF":2.1,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13546416/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148880577","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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