Journal of the Medical Sciences (Berkala Ilmu Kedokteran)最新文献

{"title":"Minnesota Multiphasic Personality Inventory 2 (MMPI 2) examination in patients with benzodiazepine addiction in Yogyakarta","authors":"Silas Henry Ismanto, Irwan Supriyanto","doi":"10.19106/JMEDSCI004703201502","DOIUrl":"https://doi.org/10.19106/JMEDSCI004703201502","url":null,"abstract":"Addiction is a major health problem in Indonesia. The prevalence and pattern of drugsaddiction shifted according to changes in personality, stressors, or increasing responsibilityas people grow. Individual personality will affect their tendency to develop drug addiction.Benzodiazepines abuse has steadily increased. Unlike other type drugs of abuse, thecharacteristics of benzodiazepine abusers are greatly varied. Therefore, the personalitytraits and social economic factors involved in the benzodiazepine addiction are unique.In this study we evaluated the personality traits of patient with benzodiazepine addictionin Yogyakarta using Minnesota Multiphasic Personality Inventory (MMPI) 2 test. Thisstudy was a descriptive analytic study with a cross sectional design. Subjects were 39benzodiazepine addicts obtained from private psychiatrist practices in Yogyakarta. Theinstruments used were questionnaire for personal information and MMPI 2. Statisticalanalysis was conducted with SPSS ver. 17 and significance level was defined at p<0.05.MMPI 2 test revealed a low total mental capacity index and a low basic personality index(OCEAN: openness, conscientiousness, extraversion, agreeableness, and neuroticism).The clinical profiles examination showed profile of somatic symptoms due to psychologicaldisturbances, clinical symptoms of overt suspiciousness, overt negative emotionality,clinical symptoms of depression, symptoms of psychopathic behaviours (antisocial),emotional difficulty in interpersonal relationship, clinical symptoms related to overtemotion, and weird and bizarre psychological experiences. There are certain personalityvariables that may be important predictors for benzodiazepine addiction identified in thisstudy.","PeriodicalId":173108,"journal":{"name":"Journal of the Medical Sciences (Berkala Ilmu Kedokteran)","volume":"15 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2016-06-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"128243810","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Expression of receptor advanced glycation end products (RAGE) and histological picture of pancreatic -cells of streptozotocin-induced diabetic rats after yellow soybean powder suspension (Glycine max) administration","authors":"Dominggos Gonsalves Sri Lestari Sulistyo Sri Kadarsih Soejono","doi":"10.19106/jms.2014/001","DOIUrl":"https://doi.org/10.19106/jms.2014/001","url":null,"abstract":"","PeriodicalId":173108,"journal":{"name":"Journal of the Medical Sciences (Berkala Ilmu Kedokteran)","volume":"115 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2015-11-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"131446179","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Cost-effectiveness comparison between caudal block and intravenous ketorolac as an early post-operative analgesic in pediatric patients underwent surgery below umbilicus segment","authors":"J. Kurniawaty, M. Abubakar, D. Sari","doi":"10.19106/JMEDSCIE004601201403","DOIUrl":"https://doi.org/10.19106/JMEDSCIE004601201403","url":null,"abstract":"Post-operative pain treatment in pediatric is frequently inadequate that could lead to psychological, physiological and behavioral changes. Therefore, adequate pediatric pain management is needed. Some analgesics such as ketorolac and regional anesthesia techniques such as caudal block have been applied to relieve pain. Ketorolac and caudal block have its own advantages and disadvantages. The aim of study was to compare the cost-effectiveness of ketorolac and caudal blok as a post-operative analgesic in pediatric. This was double blind randomized controlled clinical trial with parallel design conducted in Dr. Sardjito General Hospital. The subjects were children who underwent surgery below umbilicus segment. Seventy patients were randomly divided into two groups with 35 patients in each group. Group I (Caudal block Group) was given caudal block with bupivacaine 0.12% 1 mL/kg body weight (BW) whereas Group II (Ketorolac Group) was given ketorolac 0.5 mg/kg BW intravenously (IV). The patient’s pain was scored at 0, 15, 30, 45 minute and 1, 2, 3 hours after the conscious patients using modified Children’s Hospital of Eastern Ontario Pain Scale (mCHEOPS). Furthermore, the cost-effectiveness the both interventions was also compared. The caudal block was more effective in reducing pain than the ketorolac at minutes 0 (27/8 vs 10/25) and 15 (34/1 vs 18/17) (p<0.05). However, at third hour the ketorolac revealed more effective than the caudal block (29/6 vs 32/3) (p<0.05). The cost of the caudal block was higher than the ketorolac (IDR 95.860 ± 5.745 vs IDR 7.200 ± 14.886) (p <0.05). However, the length of stay after the caudal block was shorter than the ketorolac (40.43 ± 13.899 vs 48.57 ± 14.068) (p <0.05). Morphine was more needed for rescue analgesic in the ketorolac (p < 0.05) in first hour of operation, whereas after three hour operation paracetamol was more needed in caudal block (p < 0.05). In conclusion, the caudal block is not more cost-effective than ketorolac in reducing post-operative pain in pediatric patients underwent surgery below umbilicus segment.","PeriodicalId":173108,"journal":{"name":"Journal of the Medical Sciences (Berkala Ilmu Kedokteran)","volume":"7 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2014-08-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"123845672","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}