Journal of the Royal Society of Medicine最新文献

{"title":"Deriving and validating a risk prediction model for long COVID: a population-based, retrospective cohort study in Scotland.","authors":"Karen Jeffrey, Vicky Hammersley, Rishma Maini, Anna Crawford, Lana Woolford, Ashleigh Batchelor, David Weatherill, Chris White, Tristan Millington, Robin Kerr, Siddharth Basetti, Calum Macdonald, Jennifer K Quint, Steven Kerr, Syed Ahmar Shah, Amanj Kurdi, Colin R Simpson, Srinivasa Vittal Katikireddi, Igor Rudan, Chris Robertson, Lewis Ritchie, Aziz Sheikh, Luke Daines","doi":"10.1177/01410768241297833","DOIUrl":"10.1177/01410768241297833","url":null,"abstract":"<p><strong>Objectives: </strong>Using electronic health records, we derived and internally validated a prediction model to estimate risk factors for long COVID and predict individual risk of developing long COVID.</p><p><strong>Design: </strong>Population-based, retrospective cohort study.</p><p><strong>Setting: </strong>Scotland.</p><p><strong>Participants: </strong>Adults (≥18 years) with a positive COVID-19 test, registered with a general medical practice between 1 March 2020 and 20 October 2022.</p><p><strong>Main outcome measures: </strong>Adjusted odds ratios (aORs) with 95% confidence intervals (CIs) for predictors of long COVID, and patients' predicted probabilities of developing long COVID.</p><p><strong>Results: </strong>A total of 68,486 (5.6%) patients were identified as having long COVID. Predictors of long COVID were increasing age (aOR: 3.84; 95% CI: 3.66-4.03 and aOR: 3.66; 95% CI: 3.27-4.09 in first and second splines), increasing body mass index (BMI) (aOR: 3.17; 95% CI: 2.78-3.61 and aOR: 3.09; 95% CI: 2.13-4.49 in first and second splines), severe COVID-19 (aOR: 1.78; 95% CI: 1.72-1.84); female sex (aOR: 1.56; 95% CI: 1.53-1.60), deprivation (most versus least deprived quintile, aOR: 1.40; 95% CI: 1.36-1.44), several existing health conditions. Predictors associated with reduced long COVID risk were testing positive while Delta or Omicron variants were dominant, relative to when the Wild-type variant was dominant (aOR: 0.85; 95% CI: 0.81-0.88 and aOR: 0.64; 95% CI: 0.61-0.67, respectively) having received one or two doses of COVID-19 vaccination, relative to unvaccinated (aOR: 0.90; 95% CI: 0.86-0.95 and aOR: 0.96; 95% CI: 0.93-1.00).</p><p><strong>Conclusions: </strong>Older age, higher BMI, severe COVID-19 infection, female sex, deprivation and comorbidities were predictors of long COVID. Vaccination against COVID-19 and testing positive while Delta or Omicron variants were dominant predicted reduced risk.</p>","PeriodicalId":17271,"journal":{"name":"Journal of the Royal Society of Medicine","volume":" ","pages":"402-414"},"PeriodicalIF":8.8,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11574934/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142648346","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"For more events and to book online, please visit www.rsm.ac.uk/diary.","authors":"","doi":"10.1177/01410768241306672","DOIUrl":"https://doi.org/10.1177/01410768241306672","url":null,"abstract":"","PeriodicalId":17271,"journal":{"name":"Journal of the Royal Society of Medicine","volume":"117 12","pages":"418"},"PeriodicalIF":8.8,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142854425","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Doctors working in teams.","authors":"Dinesh Bhugra","doi":"10.1177/01410768241289860","DOIUrl":"10.1177/01410768241289860","url":null,"abstract":"","PeriodicalId":17271,"journal":{"name":"Journal of the Royal Society of Medicine","volume":" ","pages":"398-401"},"PeriodicalIF":8.8,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11577550/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142668195","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"For more events and to book online, please visit www.rsm.ac.uk/diary.","authors":"","doi":"10.1177/01410768241306672","DOIUrl":"10.1177/01410768241306672","url":null,"abstract":"","PeriodicalId":17271,"journal":{"name":"Journal of the Royal Society of Medicine","volume":"117 12","pages":"418"},"PeriodicalIF":8.8,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11662317/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143032691","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"From <i>JRSM Open</i>.","authors":"","doi":"10.1177/01410768241308897","DOIUrl":"10.1177/01410768241308897","url":null,"abstract":"","PeriodicalId":17271,"journal":{"name":"Journal of the Royal Society of Medicine","volume":"117 12","pages":"417"},"PeriodicalIF":8.8,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11662325/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142854430","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The Sovietisation of British medicine.","authors":"Richard Spicer","doi":"10.1177/01410768241289064","DOIUrl":"10.1177/01410768241289064","url":null,"abstract":"","PeriodicalId":17271,"journal":{"name":"Journal of the Royal Society of Medicine","volume":" ","pages":"360"},"PeriodicalIF":8.8,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11572712/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142502836","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"John Clark 1780 and 1792: learning from properly kept records.","authors":"Ulrich Tröhler","doi":"10.1177/01410768241290735","DOIUrl":"10.1177/01410768241290735","url":null,"abstract":"","PeriodicalId":17271,"journal":{"name":"Journal of the Royal Society of Medicine","volume":"117 11","pages":"382-383"},"PeriodicalIF":8.8,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11639023/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142818491","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Will four-year medical degrees solve the crisis in medical education?","authors":"Kamran Abbasi","doi":"10.1177/01410768241306006","DOIUrl":"10.1177/01410768241306006","url":null,"abstract":"","PeriodicalId":17271,"journal":{"name":"Journal of the Royal Society of Medicine","volume":"117 11","pages":"359"},"PeriodicalIF":8.8,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11639019/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142818492","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"From <i>JRSM Open</i>.","authors":"","doi":"10.1177/01410768241306007","DOIUrl":"10.1177/01410768241306007","url":null,"abstract":"","PeriodicalId":17271,"journal":{"name":"Journal of the Royal Society of Medicine","volume":"117 11","pages":"384"},"PeriodicalIF":8.8,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11639011/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142818490","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"For more events and to book online, please visit www.rsm.ac.uk/diary.","authors":"","doi":"10.1177/01410768241306342","DOIUrl":"10.1177/01410768241306342","url":null,"abstract":"","PeriodicalId":17271,"journal":{"name":"Journal of the Royal Society of Medicine","volume":"117 11","pages":"385"},"PeriodicalIF":8.8,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11639015/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142818488","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}