Journal of Science: Advanced Materials and Devices最新文献

{"title":"Temperature-dependent properties of Cu-doped ZnTe thin films deposited on ultra-thin glass substrates via RF magnetron sputtering","authors":"Nur Irwany Ahmad ,&nbsp;Ahmad Wafi Mahmood Zuhdi ,&nbsp;Camellia Doroody ,&nbsp;Yap Boon Kar ,&nbsp;Mohd Nazri Abd Rahman ,&nbsp;Kazi Sajedur Rahman ,&nbsp;Mohd Natashah Norizan ,&nbsp;Muhammad Najib Harif ,&nbsp;Tiong Sieh Kiong","doi":"10.1016/j.jsamd.2024.100836","DOIUrl":"10.1016/j.jsamd.2024.100836","url":null,"abstract":"<div><div>This study investigates the viability of Cu-doped ZnTe as a potential back surface field (BSF) layer on flexible CdTe thin-film solar cells, examining its structural, morphological, optical, and electrical properties. ZnTe, 5%, and 8% Cu-doped ZnTe were deposited on ultra-thin glass (UTG) substrates using the radio frequency (RF) magnetron sputtering approach at varying substrate temperatures from room temperature to 300 °C. The finding reveals that the surface morphology significantly changes as the substrate temperature increases. Besides, incorporating Cu into ZnTe resulted in a denser and rougher surface, likely due to material densification and accelerated grain growth at higher temperatures. X-ray diffraction (XRD) analysis indicated that the crystallite size of the ZnTe and Cu-doped ZnTe increased with higher temperatures. Optical spectroscopy results demonstrated an increase in the optical band gap of ZnTe with increasing substrate temperature, while Cu-doping introduced a significant variability in the bandgap, particularly at different doping levels. In terms of electrical properties, ZnTe thin films exhibited carrier concentrations around 10¹⁴ cm⁻³. Conversely, the introduction of 5% and 8% Cu into ZnTe increased carrier concentrations, ranging from 10¹⁷ to 10²⁰ cm⁻³, respectively, depending on substrate temperature and the amount of Cu concentration. Introducing Cu in the ZnTe structure may modify the characteristics of ZnTe thin films, potentially influencing its suitability as a BSF layer in CdTe solar cells by affecting its structural, optical, and electrical properties.</div></div>","PeriodicalId":17219,"journal":{"name":"Journal of Science: Advanced Materials and Devices","volume":"10 1","pages":"Article 100836"},"PeriodicalIF":6.7,"publicationDate":"2024-12-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143102323","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Nanosecond laser structuring for improving rate capability of lithium iron phosphate cathode","authors":"Dongkyu Park ,&nbsp;Dongkyoung Lee","doi":"10.1016/j.jsamd.2024.100840","DOIUrl":"10.1016/j.jsamd.2024.100840","url":null,"abstract":"<div><div>LiFePO₄ cathode's low-capacity retention at high current rates is due to its low electrical conductivity. To address this, a three-dimensional cathode was fabricated using a nanosecond laser. Its performance was studied based on groove aspect ratios (0.39, 0.96) and pitch distances (112 μm, 224 μm). Groove morphology varied with laser parameters. Cathodes with higher aspect ratios exhibited lower internal resistance. However, capacity decreased as groove pitch distance narrowed. The normalized specific capacity of the 3D cathode with an aspect ratio of 0.36 and a pitch distance of 224 μm was 6% higher than that of an unstructured cathode at a 2C rate.</div></div>","PeriodicalId":17219,"journal":{"name":"Journal of Science: Advanced Materials and Devices","volume":"10 1","pages":"Article 100840"},"PeriodicalIF":6.7,"publicationDate":"2024-12-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143102320","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Fabrication and wetting characteristics of copper thin film: An active layer for SPR-based sensor applications","authors":"Mohammad Kamal Hossain ,&nbsp;Abdullah Aljishi ,&nbsp;Firoz Khan ,&nbsp;Anwar Ul-Hamid ,&nbsp;Md Mosaddequr Rahman","doi":"10.1016/j.jsamd.2024.100839","DOIUrl":"10.1016/j.jsamd.2024.100839","url":null,"abstract":"<div><div>In this work, a simple and two-step process was demonstrated to develop multifunctional Cu-based thin films that would be suitable for thin film photoactive devices. Cu thin films on quartz glass substrates were prepared using a sputtering technique followed by a thermal treatment. The samples were annealed at high temperatures such as 200, 400, and 600 °C for 2 h in a tubular furnace. Surface morphology and elemental composition were investigated using a high-resolution scanning electron microscope (FESEM) and SEM-aided energy dispersion spectroscopy (EDS), respectively. At high temperatures, the thin films were found to have clusters and voids. Detailed studies on optical properties such as ultraviolet–visible (UV–vis) absorptions, energy band gaps and Urbach energies have been carried out. A red shift in absorption edges (from 464 to 616 nm), a decrease in energy band gaps (from 2.38 to 1.54 eV) and an increase in Urbach energies (from 193 to 272 meV) were observed for those samples annealed at higher temperatures. Sessile drop tests were carried out to find the wetting contact angle (WCA) and to demonstrate the hydrophobicity of the thin film of pristine Cu and those treated at high temperatures. An approximate WCA of 71.9° was determined for the Cu thin film. Following treatment at 200 °C and 400 °C, respectively, the samples' surfaces increased in hydrophobicity by 92.4° and 85.2°. Nevertheless, the same thin film's WCA was decreased and its hydrophilicity increased during additional annealing. Cu-based thin films have been suggested as the active layer in an SPR sensor model, and the spectrum and angular resolved reflectance properties have been thoroughly investigated. At spectral wavelengths of 600, 700, and 800 nm, the optimum thickness of Cu thin film was determined to be 40 nm at SPR angles of 44.7°, 42.7°, and 42.15°.</div></div>","PeriodicalId":17219,"journal":{"name":"Journal of Science: Advanced Materials and Devices","volume":"10 1","pages":"Article 100839"},"PeriodicalIF":6.7,"publicationDate":"2024-12-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143102319","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Ternary Bi2O3/(BiO)2CO3/g-C3N4 multi-heterojunction nanoflakes for highly efficient photocatalytic degradation of dyes and xanthates under visible light","authors":"E. Hashemi,&nbsp;R. Poursalehi,&nbsp;H. Delavari","doi":"10.1016/j.jsamd.2024.100834","DOIUrl":"10.1016/j.jsamd.2024.100834","url":null,"abstract":"<div><div>To enhance the separation efficiency of photogenerated carriers, the formation of photocatalysts with strong interfacial contact heterojunctions is considered an effective approach for the removal of diverse environmental contaminants. In this study, a ternary heterojunction photocatalyst, Bi₂O₃/(BiO)₂CO₃/g-C₃N₄, demonstrated a multifunctional high photocatalytic performance in the degradation of various dyes, including methyl orange (MO), methylene blue (MB), rhodamine B (RB) and xanthates such as potassium ethyl xanthate (PEX), potassium amyl xanthate (PAX) and sodium isopropyl xanthate (SIPX), under visible light irradiation. The Bi₂O₃/(BiO)₂CO₃/g-C₃N₄ photocatalyst was synthesized by heating a mixture of urea and arc discharge synthesized Bi₂O₃-based nanoparticles at 550 °C. This photocatalyst exhibited higher photocatalytic activity compared to Bi₂O₃/(BiO)₂CO₃ and g-C₃N₄. The photocatalysts were characterized and studied by FTIR, XRD, FESEM-EDS elemental mapping, HR-TEM, UV–visible, BET and PL. The formation of an interface between Bi₂O₃/(BiO)₂CO₃ and g-C₃N₄ significantly improved photocatalytic performance by facilitating the effective separation of photogenerated electron-hole pairs. Stability tests of Bi₂O₃/(BiO)₂CO₃/g-C₃N₄ during the degradation of MO demonstrated the photocatalyst's excellent stability and reusability, indicating its potential for practical applications in mineral processing wastewater treatment. Reactive species trapping experiments revealed that holes (h⁺) played the most significant role in photodegradation, followed by hydroxyl radicals (^•OH), while superoxide radicals (^•O₂⁻) had a lesser impact. Study of two possible photocatalytic mechanisms suggested that the transfer of photogenerated carriers in Bi₂O₃/(BiO)₂CO₃/g-C₃N₄ is more likely to follow a double Z-scheme photocatalytic system. The enhanced photocatalytic performance of Bi₂O₃/(BiO)₂CO₃/g-C₃N₄ can be attributed to considerable specific surface area, stronger visible light absorption and most importantly, well-matched band potentials between Bi₂O₃, (BiO)₂CO₃, and g-C₃N₄. The promising photocatalytic performance of Bi₂O₃/(BiO)₂CO₃/g-C₃N₄, introduces a notable photocatalyst for photodegradation of dyes and xanthates in mineral processing wastewater.</div></div>","PeriodicalId":17219,"journal":{"name":"Journal of Science: Advanced Materials and Devices","volume":"10 1","pages":"Article 100834"},"PeriodicalIF":6.7,"publicationDate":"2024-12-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143102305","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Exploring modified cyclodextrins for enhanced encapsulation and release of ethinyl estradiol: Physicochemical characterization and kinetic modeling","authors":"Mehrdad Hadadian,&nbsp;Behnam Mahdavi,&nbsp;Esmail Rezaei-Seresht","doi":"10.1016/j.jsamd.2024.100837","DOIUrl":"10.1016/j.jsamd.2024.100837","url":null,"abstract":"<div><div>Ethinyl estradiol (EE) is a synthetic derivative of steroids that is prescribed for treating sexual diseases. Cyclodextrins (CDs) can enhance the solubility, side effects, and physical characteristics of steroids by the formation of an inclusion complex. This study has aimed to provide a comparison between the encapsulated ethinyl estradiol with carboxymethyl-β-CD (CM-β-CD) and β-CD. For this purpose, different steps of the experiments were monitored using FT-IR, XRD, BET, DLS, and Zeta analyses. The morphology of the prepared inclusion complexes was investigated using FE-SEM imaging that shows nano-sized products with non-spherical structures. The thermal stability of EE and its final compounds were assessed through TGA analysis. In addition, encapsulation efficiency (EE%), phase solubility study, <em>in vitro</em> drug release, and their related kinetic studies were conducted by using the UV–visible spectroscopic method. The obtained data reveals that CM-β-CD/EE has roughly 1.5-fold higher water solubility. Besides, the cumulative release for CM-β-CD/EE was found to be 97%, while it was 46% for β-CD/EE. In contrast, the efficacy of the encapsulation process for β-CD was fairly more impressive than CM-β-CD by 97.5 and 90.62, respectively. Phase solubility kinetic study shows the negative enthalpy by −10.91∗10⁴ J/mol for β-CD/EE and −8.32∗10⁴ for CM-β-CD/EE denoting the favored complexation process and the negative entropy by −2.9∗10² J/mol.K for β-CD/EE and −2.07∗10² J/mol.K for CM-β-CD/EE implying an increase in the order of systems for both complexes. Moreover, the study of the kinetic <em>in vitro</em> drug release exhibits two different mathematical models for products with the same release mechanism, non-Fickian, which is governed by multiple processes.</div></div>","PeriodicalId":17219,"journal":{"name":"Journal of Science: Advanced Materials and Devices","volume":"10 1","pages":"Article 100837"},"PeriodicalIF":6.7,"publicationDate":"2024-12-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143092757","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Investigation on the microstructure evolution and strengthening behavior of rolled bonding Cu strip","authors":"Jun Cao ,&nbsp;Junchao Zhang ,&nbsp;Huiyi Tang ,&nbsp;Xiaoyu Shen ,&nbsp;Kexing Song ,&nbsp;Yanjun Zhou ,&nbsp;Chengqiang Cui","doi":"10.1016/j.jsamd.2024.100835","DOIUrl":"10.1016/j.jsamd.2024.100835","url":null,"abstract":"<div><div>The relationship and influencing mechanism among the reduction rate, the strengthening behavior and the microstructure evolution of rolled Cu strips were studied. It was found that with the increase of reduction rate, the uneven deformation behavior of the Cu strip was divided into three zones. The grain size in Zone I was refined accompanied by large-scale entangled dislocations, and a nanosheet layered texture was formed. The primary reason for the increase in the strength of the Cu strip is the combined strengthening effect of dislocation, grain boundary and texture, as well as the strengthening effect provided by some lattice friction. The grain orientation exhibited periodic transitions between &lt;110&gt; and &lt;111&gt;, &lt;001&gt;, which provides assistance for grain refinement and dislocation accumulation. The grains in the fracture zone of the Cu strip are elongated and refined during stretching, and flow towards the central axis of the cross-section. The fracture mechanism has shifted from cutting to a chip edge/point to a combined action of multiple mechanisms, which is also accompanied by a gradual increase in the “tearing angle\".</div></div>","PeriodicalId":17219,"journal":{"name":"Journal of Science: Advanced Materials and Devices","volume":"10 1","pages":"Article 100835"},"PeriodicalIF":6.7,"publicationDate":"2024-12-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143102322","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Tuning of magnetic properties and giant magnetoimpedance effect in multilayered microwires","authors":"R. López Antón ,&nbsp;J.P. Andrés ,&nbsp;J.A. González ,&nbsp;A. García-Gómez ,&nbsp;V. Zhukova ,&nbsp;A. Chizhik ,&nbsp;M. Salaheldeen ,&nbsp;A. Zhukov","doi":"10.1016/j.jsamd.2024.100821","DOIUrl":"10.1016/j.jsamd.2024.100821","url":null,"abstract":"<div><div>We studied the magnetic properties and Giant Magnetoimpedance (GMI) effect in amorphous Co-rich microwires with similar chemical compositions and different diameters with magnetic (Co, Permalloy) and non-magnetic (Cu) layers deposited by magnetic sputtering onto glass-coating. Studies of magnetic properties and GMI effect of as-prepared microwires and the same microwires with deposited magnetic and non-magnetic layers reveal substantial impact of such layers on GMI effect and hysteresis loops. Both as-prepared samples present soft magnetic properties and high GMI effect. The contribution of magnetic layers is observed in hysteresis loop at higher magnetic field, with hysteresis loops similar to those observed in microwires with mixed amorphous-crystalline structure. Meanwhile, both magnetic and non-magnetic layers affect low field hysteresis loops of both samples. Additionally, the GMI ratio, ΔZ/Z, and magnetic field dependences of GMI ratio are substantially affected by the presence of magnetic and non-magnetic layers deposited onto glass-coating. We discussed the observed experimental dependences considering both change of the internal stresses originated by the sputtered layer as well as the magnetostatic interaction between the amorphous ferromagnetic nucleus and deposited magnetic layers.</div></div>","PeriodicalId":17219,"journal":{"name":"Journal of Science: Advanced Materials and Devices","volume":"9 4","pages":"Article 100821"},"PeriodicalIF":6.7,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142743194","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Corrigendum to “Innovative device for in-vivo quantitative assessment of different wire materials using 3D models” [J. Sci.: Adv. Mater. and Dev. (9), Issue 1, March 2024, 100667]","authors":"Mahmoud Sedky Adly ,&nbsp;Aya Sedky Adly ,&nbsp;Afnan Sedky Adly ,&nbsp;Delphine Carayon ,&nbsp;Philippe Bousquet ,&nbsp;Elias Estephan ,&nbsp;Frederic Cuisinier","doi":"10.1016/j.jsamd.2024.100811","DOIUrl":"10.1016/j.jsamd.2024.100811","url":null,"abstract":"","PeriodicalId":17219,"journal":{"name":"Journal of Science: Advanced Materials and Devices","volume":"9 4","pages":"Article 100811"},"PeriodicalIF":6.7,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143172157","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Proanthocyanidin-Imbued cellulosic 3-Dimensional intrinsic aligned Nanostructures: A novel approach for dental and bone regeneration using dental pulp derived stem cells","authors":"Ahmad Hasanzadeh ,&nbsp;Atefeh Alipour ,&nbsp;Sajedeh Ghasemi ,&nbsp;Saadi Hosseini ,&nbsp;Naser Farrokhi ,&nbsp;Peng-Yuan Wang ,&nbsp;Ali Zarrabi ,&nbsp;Javad Mohammadi ,&nbsp;Hosein Shahsavarani","doi":"10.1016/j.jsamd.2024.100820","DOIUrl":"10.1016/j.jsamd.2024.100820","url":null,"abstract":"<div><div>Developing effective scaffolds to address significant bone and dental defects is crucial in regenerative osteal and dental medicine. Traditional methods utilizing synthetic micropatterned scaffolds have effectively stimulated osteogenic and odontogenic differentiation of stem cells through parallel, 3D topographic, hexagonal, and elongated architectural features. However, these approaches face significant cost, scalability, and biocompatibility challenges. Recent advancements have highlighted the potential of decellularized plant scaffolds, such as those derived from <em>Beaucarnea recurvata</em> leaves (BLDS). These offer intrinsic microstructural advantages with solving reproducibility, scalability, incurred cost, and biocompatibility challenges. This study explores the enhancement of BLDS using grape seed proanthocyanidin extract (GSPE), a natural polyphenol known for its beneficial effects on bone and dental stem cell differentiation. By functionalizing BLDS with GSPE, we investigated its impact on osteogenic and odontogenic differentiation of human dental pulp-derived mesenchymal stem cells (DPDMSCs). The modified scaffolds exhibited improved physicochemical properties, including enhanced cell proliferation, protein absorption, scaffold interactions, and upregulated osteogenic and dental marker gene expression. SEM imaging revealed significant cellular growth and morphological changes indicative of successful differentiation. Furthermore, BLDS-GSPE demonstrated increased ALP activity and mineral deposition, suggesting its potential as a cost-effective, reproducible and biocompatible alternative for bone and dental repair compared to conventional synthetic biomaterials.</div></div>","PeriodicalId":17219,"journal":{"name":"Journal of Science: Advanced Materials and Devices","volume":"9 4","pages":"Article 100820"},"PeriodicalIF":6.7,"publicationDate":"2024-11-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142703188","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The green formulation of silver nanoparticles for the anticancer and lupus nephritis treatment applications and reducing the inflammatory cytokines in the rat periodontal model","authors":"Yan Sun,&nbsp;Qingfei Yu","doi":"10.1016/j.jsamd.2024.100822","DOIUrl":"10.1016/j.jsamd.2024.100822","url":null,"abstract":"<div><div>In this study, a novel bio-inspired synthesis for the preparation of Ag NPs by <em>Calendula persica</em> flower extract has been researched. Also, the effects of the recent composite on lupus nephritis by following the TGF-β1 signaling pathway in mice and gingival amounts of IL1-β and TNF-α in the animal periodontal model were determined. To assess the crystal nature, morphology and size of the prepared nanoparticles, X-ray diffraction (XRD), transmission electron microscopy (TEM), ultraviolet–visible (UV–Vis) and field emission-scanning electron microscopy (FE-SEM) analyses were applied in this study. The prepared Ag NPs was employed for its effectiveness against colon cancer cell line (C26). The bio-synthesized Ag NPs had also cytotoxic property versus colon cancer based on MTT protocol. Collectively, the Ag NPs fabricated by biological way has potential applications in inflammatory treatment. In lupus nephritis section, indexes in animal tissues and serum were identified using specific kits, while pathological alterations in the mice kidney were examined through H&amp;E staining. Additionally, qPCR was employed to determine the expression related to TGF-β 1 in kidney, thereby providing further insight into the silver nanoparticles mechanism. The findings indicated that silver nanoparticles reduced the mRNA expression levels of TGF-β 1 and NF-κB in the kidneys, while simultaneously increasing the Mn-SOD and IκB-α expression. Histological examination of H&amp;E-stained sections revealed that silver nanoparticles mitigated the morphological abnormalities of the glomeruli and the inflammatory infiltration associated with nephritis. Silver nanoparticles demonstrated an inhibitory effect on the dsDNA positive rate in animal suffering from nephritis. Silver nanoparticles were found to reduce the increase in urinary protein and the pro-inflammatory cytokines concentrations in both the kidney and serum. In the periodontal model study, 0–3 ligatures were applied to induce the inflammatory periodontitis in right mandibular first molar neck in rats. The levels of inflammatory cytokines (IL1-β, CINC-1, IL-10 and TNF-α) were determined by common immunological test, ELISA. The findings revealed that Ag NPs administration could decease the IL1-β and TNF-α production in the rat periodontal model gum tissue. In addition, the outcome of this research indicated that IL1-β and TNF-α levels raised in the rat periodontal model gum tissue compared to control group. Ag NPs increased the levels of superoxide dismutase, catalase, and plasma bone alkaline phosphatase and reduced the IL1-β, TNF-α, inducible nitric oxide synthase and RANK genes mRNA expression. The results indicate that pre/post-treatment with Ag NPs because of its direct activity on pro-inflammatory cytokines inhibition improved the inflammatory symptoms in the periodontitis and lupus nephritis animals.</div></div>","PeriodicalId":17219,"journal":{"name":"Journal of Science: Advanced Materials and Devices","volume":"10 2","pages":"Article 100822"},"PeriodicalIF":6.7,"publicationDate":"2024-11-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143851795","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}