{"title":"Polymeric micelles in TKIs’ delivery for cancer treatment","authors":"B. Dashtipour","doi":"10.52319/j.nanoscitec.2022.15","DOIUrl":"https://doi.org/10.52319/j.nanoscitec.2022.15","url":null,"abstract":"Polymeric micelles (PMs), one of the most popular nanotechnology platforms for the delivery of various kinds of chemotherapeutics, are aggregated colloids formed through the self-assembling of amphiphilic block copolymers in an aqueous solvent. The popularity of PMs is owing to several unique physicochemical characteristics such as small size, biocompatibility, core-shell arrangement, high drug loading capacity, and favorable solubility. There is a plethora of studies on the use of these nano-delivery systems over years to overcome the issues related to drug administration, like low water solubility.Tyrosine kinase inhibitors (TKIs) are targeted therapy agents that constitute a significant part of cancer treatment modality due to targeting key biological molecules (EGFRs, PDGFR, and HER2) largely involved in the progression of cancer. However, issues associated with TKIs such as water-insolubility, short circulation time, systemic toxicity, and drug resistance pose challenges in the way of cancer therapy. In the present review, in addition to providing an introduction to micelles and different types of block copolymers, we attempt to present the latest information on clinical and preclinical research on employing PMs to deliver different TKIs to various types of tumors.","PeriodicalId":172021,"journal":{"name":"Journal of NanoScience Technology","volume":"25 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"128222724","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Effective nano Cyclodextrin-TKIs drug delivery for cancer therapy","authors":"M. Dastjerdi","doi":"10.52319/j.nanoscitec.2022.14","DOIUrl":"https://doi.org/10.52319/j.nanoscitec.2022.14","url":null,"abstract":"Nanotechnology-based studies pursuing the innovative cancer treatment methods, particularly using drug delivery systems, have significantly increased over the past few years. Some of the impacts of using such systems include the increased cytotoxic activity of drugs, reduced unwanted side effects, and a more stable and controlled release of drugs. Particularly using the targeted delivery systems with helping novel nanocarriers made it possible to kill cancer cells specifically. Meanwhile, Cyclodextrins were known as natural cyclic oligosaccharides which serve the intended purposes. Many cancer researchers were interested in them due to the multiple advantages of a variety of materials utilized as nanocarriers for medication delivery. Regarding their unique structure, they can benefit hydrophobic and hydrophilic drugs. On the other hand, tyrosine kinase inhibitors, with their properties to inhibit the growth of cancer cells, are the valuable drugs of choice for various types of cancer. In this regard, cyclodextrins were used as nano-drug delivery systems to transport tyrosine kinase inhibitors in recent studies by researchers. In this review, some recent medical applications of cyclodextrin-based nanocarriers for the delivery of tyrosine kinase inhibitors and the synthesis methods of cyclodextrin-based compounds have been discussed, and the advantages and disadvantages of using cyclodextrin along with tyrosine kinase inhibitors in the treatment of various cancers were mentioned.","PeriodicalId":172021,"journal":{"name":"Journal of NanoScience Technology","volume":"19 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"134199019","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Nano drug delivery systems as promising tools for cancer therapy","authors":"Z. Abbasi Radmoghaddam","doi":"10.52319/j.nanoscitec.2022.12","DOIUrl":"https://doi.org/10.52319/j.nanoscitec.2022.12","url":null,"abstract":"Despite the remarkable medical advances, cancer is still a lethal threat to humans, causing tremendous social and economic problems. The emerging and following developments of nanomedicine for cancer therapy during past recent years brought outstanding achievements to the healthcare industry. Nanoparticle-based carriers to deliver various anti-cancer drugs opened new doors to boost the efficiencies of conventional chemotherapeutic approaches and decrease serious side effects. Although some challenges like drug resistance, instability, inappropriate accumulation, and drug leakage have remained, some delivery systems have achieved hopeful results in clinical trials, and consequently, some of them were approved by U.S Food and Drug Administration (FDA). In this review, the most essential and promising anticancer drug delivery systems for cancer treatment, particularly non-small cell lung cancer (NSCLC), are described. The primary emphasis was on evaluating different FDA-Approved ones in order to get a comprehensive grasp of their benefits and drawbacks for future research and industrial uses.","PeriodicalId":172021,"journal":{"name":"Journal of NanoScience Technology","volume":"24 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-08-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"116618548","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Different methods for returning PET into the economic cycle: A review","authors":"M. Masoumi","doi":"10.52319/j.nanoscitec.2022.13","DOIUrl":"https://doi.org/10.52319/j.nanoscitec.2022.13","url":null,"abstract":"Polyethylene terephthalate (PET) is a saturated polyester, which is widely utilized in the production of films, bottles, and fibers in terms of its excellent thermal stability, clarity, strength, and moldability. PET waste has increased as the manufacture and consumption of PET bottles have increased. Major environmental and financial problems have resulted from the disposal of PET bottle waste. Both clear PET bottles and colorful PET bottles are recycled using various methods. However, it is possible to recycle PET trash by chemically replicating the monomers, separating them, and creating new PET from them. Here, we review the synthesis, characterization, and different methods for PET recycling as well as the commercial exploitation associated with the recycling and re-use of them.","PeriodicalId":172021,"journal":{"name":"Journal of NanoScience Technology","volume":"85 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-08-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"126255841","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Application of copper oxide-based nanomaterials in electrochemical energy‐storage devices","authors":"","doi":"10.52319/j.nanoscitec.2022.11","DOIUrl":"https://doi.org/10.52319/j.nanoscitec.2022.11","url":null,"abstract":"Copper oxide is established as an important compound in technology due to its semi-conducting nature and high chemical stability as well as economic benefits. These features have made it a good candidate in energy storage applications. Further, extensive attention has been paid to advancement of supercapacitors- a complementary device between battery and conventional capacitors – due to their unique features such as high power, long cycle life, and environmentally friendly nature. In addition, copper oxide has sparked interest in preparation of applicable positive electrodes which can be used in preparation of supercapacitors. Meanwhile, copper oxide is mixed with polarized liquids and polymers easily, and it is has relative stable chemical and physical properties. Electrochemical features of copper oxide depend on the morphology where proper architectural design of electrode materials can be optimized in these devices. In this review, copper oxide synthesis and its redox mechanism as cathode materials will be explored as well as the application of various copper oxide compounds in preparation of high-performance supercapacitors.","PeriodicalId":172021,"journal":{"name":"Journal of NanoScience Technology","volume":"22 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-05-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"116992414","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"The investigation of hemoglobin in hypertension; spectroscopic and thermodynamic analysis","authors":"","doi":"10.52319/j.nanoscitec.2022.10","DOIUrl":"https://doi.org/10.52319/j.nanoscitec.2022.10","url":null,"abstract":"","PeriodicalId":172021,"journal":{"name":"Journal of NanoScience Technology","volume":"26 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-05-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"125007073","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"LIPID-BASED NANOFORMULATIONS FOR TKIS DELIVERY IN CANCER THERAPY","authors":"","doi":"10.52319/j.nanoscitec.2021.9","DOIUrl":"https://doi.org/10.52319/j.nanoscitec.2021.9","url":null,"abstract":"","PeriodicalId":172021,"journal":{"name":"Journal of NanoScience Technology","volume":"8 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-02-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"128082547","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Investigation of the electrochemical behavior of ZIF-67 @ carbon nanotube and graphene oxide as potential electrode active materials for supercapacitors","authors":"","doi":"10.52319/j.nanoscitec.2021.8","DOIUrl":"https://doi.org/10.52319/j.nanoscitec.2021.8","url":null,"abstract":"","PeriodicalId":172021,"journal":{"name":"Journal of NanoScience Technology","volume":"9 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-12-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"125556454","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Experimental evaluation of erythrocyte proteins membrane skeleton in hypertension","authors":"","doi":"10.52319/j.nanoscitec.2021.7","DOIUrl":"https://doi.org/10.52319/j.nanoscitec.2021.7","url":null,"abstract":"","PeriodicalId":172021,"journal":{"name":"Journal of NanoScience Technology","volume":"42 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"125562170","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"A review of Functionalized and Composited graphene-based materials: effective approach to improving tribological performance as lubricant additives","authors":"V. Baigi","doi":"10.52319/j.nanoscitec.2023.23","DOIUrl":"https://doi.org/10.52319/j.nanoscitec.2023.23","url":null,"abstract":"Recently, the reduction of friction and wear-related mechanical failures in moving mechanical systems has become increasingly important due to the negative impact of friction on durability, efficiency, and environmental friendliness. Therefore, the search continues for lubricants (solid and liquid), coatings, and novel materials that can diminish friction and wear. Materials from the graphene family are one of the largest discoveries of this era that scientists have studied. Researchers have investigated graphene family materials, which are promising additives for different lubrication systems due to their special physicochemical properties. This review provides an overview of studies conducted on the tribological properties of graphene family materials, such as graphene, functionalized graphene, composites of graphene nanoparticle-decorated graphene, and other materials. The article also discusses graphene-family materials as lubricating additives, as well as unsolved matters and optimistic perspectives in the future.","PeriodicalId":172021,"journal":{"name":"Journal of NanoScience Technology","volume":"39 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"117208465","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}