Daniella Kushnir-Grinbaum, Daranporn Triwongwaranat, Bevin Bhoyrul, John Frewen, Nicole Yoong, Blake R C Smith, Rodney Sinclair
{"title":"Continued year-on-year improvement in hair density with systemic minoxidil in women with female pattern hair loss: A case series.","authors":"Daniella Kushnir-Grinbaum, Daranporn Triwongwaranat, Bevin Bhoyrul, John Frewen, Nicole Yoong, Blake R C Smith, Rodney Sinclair","doi":"10.1016/j.jaad.2025.03.028","DOIUrl":"https://doi.org/10.1016/j.jaad.2025.03.028","url":null,"abstract":"","PeriodicalId":17198,"journal":{"name":"Journal of the American Academy of Dermatology","volume":" ","pages":""},"PeriodicalIF":12.8,"publicationDate":"2025-03-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143663839","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Jiangyuan Zhou, Yuru Lan, Tong Qiu, Zixin Zhang, Xue Gong, Xuepeng Zhang, Congxia Yang, Zilong Zhou, Yujia Zhang, Min Yang, Jianlei Fu, Chunshui He, Qiang Peng, Fan Hu, Chunchao Xia, Feiteng Kong, Siyuan Chen, Yi Ji
{"title":"Efficacy and Safety of High- vs Low-Dose Sirolimus in Patients with Kaposiform Hemangioendothelioma: A Randomized Clinical Trial.","authors":"Jiangyuan Zhou, Yuru Lan, Tong Qiu, Zixin Zhang, Xue Gong, Xuepeng Zhang, Congxia Yang, Zilong Zhou, Yujia Zhang, Min Yang, Jianlei Fu, Chunshui He, Qiang Peng, Fan Hu, Chunchao Xia, Feiteng Kong, Siyuan Chen, Yi Ji","doi":"10.1016/j.jaad.2025.03.023","DOIUrl":"https://doi.org/10.1016/j.jaad.2025.03.023","url":null,"abstract":"<p><strong>Background: </strong>It remains unknown whether low-dose sirolimus can replace high-dose sirolimus for the treatment of kaposiform hemangioendothelioma (KHE) without the Kasabach-Merritt phenomenon (KMP).</p><p><strong>Objective: </strong>To evaluate the noninferiority and safety of low-dose versus high-dose sirolimus in KHE patients.</p><p><strong>Methods: </strong>This randomized, multicenter, open-label, noninferiority trial was conducted from February 2021 to August 2022. Participants received either a low-dose sirolimus regimen (blood trough concentration 5-8 ng/mL) or a high-dose sirolimus regimen (blood trough concentration 10-15 ng/mL). The primary endpoint was the difference in the proportion of patients between groups who achieved an objective response, defined as a ≥20% reduction in KHE volume at month 12.</p><p><strong>Results: </strong>In this study, 39 were in the low-dose group, and 40 were in the high-dose group. At 1 year of treatment, 90.0% in the high-dose group and 89.7% in the low-dose group achieved an objective response (difference, 0.3%; 95% confidence interval -13.1 to 13.6). The incidences of total adverse events (AEs) and serious AEs were similar between the two groups, but respiratory, skin and mucosal AEs were less common in the low-dose group.</p><p><strong>Limitations: </strong>The patients enrolled were not associated with KMP.</p><p><strong>Conclusion: </strong>Low-dose sirolimus is noninferior to high-dose sirolimus in treating KHE.</p>","PeriodicalId":17198,"journal":{"name":"Journal of the American Academy of Dermatology","volume":" ","pages":""},"PeriodicalIF":12.8,"publicationDate":"2025-03-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143663844","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Shannon Hanggodo, Tatyana Koustov, Kelley Sharp, Jane M Grant-Kels
{"title":"Ethical Implications of Artificial IntelligenceI Written Personal Statements in Dermatology.","authors":"Shannon Hanggodo, Tatyana Koustov, Kelley Sharp, Jane M Grant-Kels","doi":"10.1016/j.jaad.2025.03.030","DOIUrl":"https://doi.org/10.1016/j.jaad.2025.03.030","url":null,"abstract":"","PeriodicalId":17198,"journal":{"name":"Journal of the American Academy of Dermatology","volume":" ","pages":""},"PeriodicalIF":12.8,"publicationDate":"2025-03-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143662712","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Diagnostic yield of testing an additional direct immunofluorescence (DIF) specimen derived at a single timepoint: A retrospective cohort study of 1438 DIF specimen pairs.","authors":"Vahide Saeidi, Heather D Hardway, Julia S Lehman","doi":"10.1016/j.jaad.2025.03.020","DOIUrl":"https://doi.org/10.1016/j.jaad.2025.03.020","url":null,"abstract":"","PeriodicalId":17198,"journal":{"name":"Journal of the American Academy of Dermatology","volume":" ","pages":""},"PeriodicalIF":12.8,"publicationDate":"2025-03-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143663841","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Gaurav N Pathak, Bianca Sanabria, Anurag N Pathak, Devina M Lohani, Shazli Razi, Babar Rao
{"title":"Vitiligo development following COVID-19 vaccination: A retrospective analysis of 128 cases using the Vaccine Adverse Events Reporting System.","authors":"Gaurav N Pathak, Bianca Sanabria, Anurag N Pathak, Devina M Lohani, Shazli Razi, Babar Rao","doi":"10.1016/j.jaad.2025.03.021","DOIUrl":"https://doi.org/10.1016/j.jaad.2025.03.021","url":null,"abstract":"","PeriodicalId":17198,"journal":{"name":"Journal of the American Academy of Dermatology","volume":" ","pages":""},"PeriodicalIF":12.8,"publicationDate":"2025-03-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143663482","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Mitchell A Taylor, Divya Sharma, Evelyn Fagan, Bianca Ituarte, Mollie Oudenhoven, Erin X Wei
{"title":"Characterizing Cutaneous Head and Neck Melanoma in Pediatric Patients: A Retrospective Cohort Study.","authors":"Mitchell A Taylor, Divya Sharma, Evelyn Fagan, Bianca Ituarte, Mollie Oudenhoven, Erin X Wei","doi":"10.1016/j.jaad.2025.03.027","DOIUrl":"https://doi.org/10.1016/j.jaad.2025.03.027","url":null,"abstract":"","PeriodicalId":17198,"journal":{"name":"Journal of the American Academy of Dermatology","volume":" ","pages":""},"PeriodicalIF":12.8,"publicationDate":"2025-03-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143663838","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Efficacy of Baricitinib in Moderate Alopecia Areata, Severe Alopecia Areata, Alopecia Totalis, and Alopecia Universalis: A Real-world Comparative Study.","authors":"Guan Jiang, Xinru Liu, Xuhui Jiang, Yaxin Zhang","doi":"10.1016/j.jaad.2025.03.026","DOIUrl":"https://doi.org/10.1016/j.jaad.2025.03.026","url":null,"abstract":"","PeriodicalId":17198,"journal":{"name":"Journal of the American Academy of Dermatology","volume":" ","pages":""},"PeriodicalIF":12.8,"publicationDate":"2025-03-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143663845","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Racha Cherradi, Abigail McKenzie, Yousef Salem, Ammar Ahmed
{"title":"Beyond Depigmentation: TriNetX Insights into Sarcoidosis Risk in Vitiligo Patients.","authors":"Racha Cherradi, Abigail McKenzie, Yousef Salem, Ammar Ahmed","doi":"10.1016/j.jaad.2025.03.029","DOIUrl":"https://doi.org/10.1016/j.jaad.2025.03.029","url":null,"abstract":"","PeriodicalId":17198,"journal":{"name":"Journal of the American Academy of Dermatology","volume":" ","pages":""},"PeriodicalIF":12.8,"publicationDate":"2025-03-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143649404","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Matthew S Goldberg, Victor Brodsky, Patrick Emanuel
{"title":"re: Limitations of the commercially available gene expression test in predicting cutaneous squamous cell carcinoma metastasis and clinical outcomes.","authors":"Matthew S Goldberg, Victor Brodsky, Patrick Emanuel","doi":"10.1016/j.jaad.2025.02.092","DOIUrl":"https://doi.org/10.1016/j.jaad.2025.02.092","url":null,"abstract":"","PeriodicalId":17198,"journal":{"name":"Journal of the American Academy of Dermatology","volume":" ","pages":""},"PeriodicalIF":12.8,"publicationDate":"2025-03-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143649407","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Christopher G Youn, Arash Pour Mohammad, Ann L Marqueling, Dawn H Siegel, Justin M Ko, Gordon H Bae
{"title":"Association Between Supplemental Nutrition Assistance Program (SNAP) and Cost-Related Medical Care Delays in Pediatric Atopic Dermatitis: A Cross-Sectional Analysis of the National Health Interview Survey, 1999-2018.","authors":"Christopher G Youn, Arash Pour Mohammad, Ann L Marqueling, Dawn H Siegel, Justin M Ko, Gordon H Bae","doi":"10.1016/j.jaad.2025.03.025","DOIUrl":"https://doi.org/10.1016/j.jaad.2025.03.025","url":null,"abstract":"","PeriodicalId":17198,"journal":{"name":"Journal of the American Academy of Dermatology","volume":" ","pages":""},"PeriodicalIF":12.8,"publicationDate":"2025-03-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143649403","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}