Journal of the American Academy of Dermatology最新文献

Drivers of overall mortality in patients with pleomorphic dermal sarcoma: A population-based analysis of the Surveillance, Epidemiology, and End Results (SEER) Program. 多形性真皮肉瘤患者总死亡率的驱动因素：监测、流行病学和最终结果 (SEER) 计划的人群分析。

IF 12.8 1区医学

Journal of the American Academy of Dermatology Pub Date : 2024-09-30 DOI: 10.1016/j.jaad.2024.09.042

Tejas P Joshi, Elena I Skaggs, Ida F Orengo

引用次数: 0

Risk of fungal infection in patients with psoriasis receiving biologics: a retrospective single-center cohort study. 接受生物制剂治疗的银屑病患者真菌感染的风险：一项回顾性单中心队列研究。

IF 12.8 1区医学

Journal of the American Academy of Dermatology Pub Date : 2024-09-30 DOI: 10.1016/j.jaad.2024.09.037

Yoshihito Minami, Junichiro Hiruma, Kazuharu Harada, Kazuki Fujimori, Risa Suzuki, Miho Mori, Masahiro Okura, Namiko Abe, Kazutoshi Harada, Yukari Okubo

{"title":"Risk of fungal infection in patients with psoriasis receiving biologics: a retrospective single-center cohort study.","authors":"Yoshihito Minami, Junichiro Hiruma, Kazuharu Harada, Kazuki Fujimori, Risa Suzuki, Miho Mori, Masahiro Okura, Namiko Abe, Kazutoshi Harada, Yukari Okubo","doi":"10.1016/j.jaad.2024.09.037","DOIUrl":"https://doi.org/10.1016/j.jaad.2024.09.037","url":null,"abstract":"Background: The risk of fungal infection in patients with psoriasis receiving biologics is not fully understood in clinical practice.Objective: To assess the incidence and the risk of fungal infection onset in patients with psoriasis receiving biologics.Methods: Retrospective cohort study of 592 psoriasis cases treated with biologics at a single center.Results: Seventy-three (12.3%) of the 592 cases involved a fungal infection. Fungal infection occurrence was more frequently associated with the use of interleukin (IL)-17 inhibitors than of other biologics. The risk factors of fungal infection were the type of biologic agent (P = .004), age at the start of biologic therapy (odds ratio [OR]: 1.04; 95% confidence interval [CI]: 1.02-1.06), and diabetes mellitus (OR: 2.40; 95% CI: 1.20-4.79).Limitations: The present, retrospective study did not include patients who did not receive biologic therapy. Moreover, the type of biologic agent used was changed in many cases.Conclusion: Psoriasis patients treated with IL-17 inhibitors were more likely to cause fungal infections, especially candidiasis, than other biologics. Moreover, the age at the start biologic therapy and diabetes mellitus onset were also independent risk factors of fungal infection.","PeriodicalId":17198,"journal":{"name":"Journal of the American Academy of Dermatology","volume":null,"pages":null},"PeriodicalIF":12.8,"publicationDate":"2024-09-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142365687","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Surgical Pearl: Optimizing earlobe repair: a modified punch technique for elongated pierced earlobe holes. 手术珍珠：优化耳垂修复：针对拉长耳垂穿孔的改良打孔技术。

IF 12.8 1区医学

Journal of the American Academy of Dermatology Pub Date : 2024-09-30 DOI: 10.1016/j.jaad.2024.09.038

I Arévalo Ortega, B Lada Colunga, Jl Artola Igarza

引用次数: 0

Commentary: Response to "Dupilumab therapy for atopic dermatitis is associated with increased risk of cutaneous T cell lymphoma: a retrospective cohort study". 评论：对 "杜匹单抗治疗特应性皮炎与皮肤T细胞淋巴瘤风险增加有关：一项回顾性队列研究 "的回应

IF 12.8 1区医学

Journal of the American Academy of Dermatology Pub Date : 2024-09-30 DOI: 10.1016/j.jaad.2024.08.082

Tien V Nguyen, Andrea Fleisch Marcus, Sarah-Jo Sinnott, Anna Coleman, Carlos Peralta, Stephane Levy, Prashant Kushwaha, Debra Sierka, Marius Ardeleanu, Ana B Rossi

引用次数: 0

Response to Ong et al., "Hair-raising costs: evaluating botulinum toxin treatment for androgenetic alopecia." 对 Ong 等人的回应，"养发成本：评估治疗雄激素性脱发的肉毒毒素"。

IF 12.8 1区医学

Journal of the American Academy of Dermatology Pub Date : 2024-09-28 DOI: 10.1016/j.jaad.2024.09.041

André Luiz Vairo Donda, Rita Fernanda Cortez de Almeida, Daniel Fernandes Melo, Paulo Müller Ramos, Carla Jorge Machado, Sidney Frattini, Daniela Alves Pereira Antelo, Carlos Baptista Barcaui

引用次数: 0

Circulating monocytes as a marker of response to adalimumab in patients with hidradenitis suppurativa: A single institution, real-world cohort study. 循环单核细胞作为化脓性扁桃体炎患者对阿达木单抗反应的标志物：一项单一机构真实世界队列研究。

IF 12.8 1区医学

Journal of the American Academy of Dermatology Pub Date : 2024-09-28 DOI: 10.1016/j.jaad.2024.09.036

Nessr Abu Rached, Jana Herbst, Thilo Gambichler, Schapoor Hessam, Lennart Ocker, Marina Skrygan, Eggert Stockfleth, Falk G Bechara

引用次数: 0

Hair-raising costs: evaluating botulinum toxin treatment for androgenetic alopecia. 养发成本：评估治疗雄激素性脱发的肉毒杆菌毒素疗法。

IF 12.8 1区医学

Journal of the American Academy of Dermatology Pub Date : 2024-09-28 DOI: 10.1016/j.jaad.2024.08.081

Michael M Ong, Jose W Ricardo, Shari R Lipner

引用次数: 0

The effect of dupilumab on caregiver- and patient-reported outcomes in young children with moderate-to-severe atopic dermatitis: results from a placebo-controlled, phase 3 study. 中度至重度特应性皮炎患儿使用杜匹单抗对护理人员和患者报告结果的影响：安慰剂对照第 3 期研究结果。

IF 12.8 1区医学

Journal of the American Academy of Dermatology Pub Date : 2024-09-28 DOI: 10.1016/j.jaad.2024.09.039

Amy S Paller, Jonathan I Silverberg, Eric L Simpson, Michael J Cork, Peter D Arkwright, Zhen Chen, Ashish Bansal, Randy Prescilla, Zhixiao Wang, Ainara R Marco

{"title":"The effect of dupilumab on caregiver- and patient-reported outcomes in young children with moderate-to-severe atopic dermatitis: results from a placebo-controlled, phase 3 study.","authors":"Amy S Paller, Jonathan I Silverberg, Eric L Simpson, Michael J Cork, Peter D Arkwright, Zhen Chen, Ashish Bansal, Randy Prescilla, Zhixiao Wang, Ainara R Marco","doi":"10.1016/j.jaad.2024.09.039","DOIUrl":"https://doi.org/10.1016/j.jaad.2024.09.039","url":null,"abstract":"Background: Moderate-to-severe atopic dermatitis (AD) greatly impacts children/caregivers.Objective: Evaluate the impact of treatment with dupilumab on caregiver- and patient-reported AD symptoms and quality of life (QoL) in young children.Methods: In the LIBERTY AD PRESCHOOL (randomized, placebo-controlled) study, children aged 6 months to 5 years with moderate-to-severe AD received dupilumab or placebo plus low-potency topical corticosteroids for 16 weeks. This post-hoc analysis assessed the change from baseline to week 16 in caregiver-reported outcome measures of AD symptoms (e.g., itch and sleep) and QoL of patients and their caregivers/families.Results: Dupilumab (n = 83) vs placebo (n = 79) provided significant improvements in caregiver-reported AD symptoms and QoL. Significant improvements were seen as early as week 4 and sustained through the end of the study. Additionally, dupilumab vs placebo provided rapid and significant improvement in QoL measures for the patients' caregivers/families.Limitations: Few patients aged <2 years; significance only reported for pre-specified endpoints; Infant's Dermatitis QoL Index severity strata adopted from Children's Dermatology Life Quality Index.Conclusion: Dupilumab improved AD symptoms and QoL in patients and their caregivers/families.","PeriodicalId":17198,"journal":{"name":"Journal of the American Academy of Dermatology","volume":null,"pages":null},"PeriodicalIF":12.8,"publicationDate":"2024-09-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142349095","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Dupilumab in atopic-dermatitis-like eczema associated with inborn errors of immunity: a nationwide study. 杜比鲁单抗治疗与先天性免疫错误相关的特应性皮炎样湿疹：一项全国性研究。

IF 12.8 1区医学

Journal of the American Academy of Dermatology Pub Date : 2024-09-27 DOI: 10.1016/j.jaad.2024.09.029

C Guillemin, N Bellon, M Jachiet, S Barbarot, E Bourrat, C Chiaverini, P Cougoul, M Ebbo, M Herber, T Hubiche, S Mallet, M Tauber, V Béziat, M Castelle, A Du Thanh, J Farhi, C Fieschi, B Fournier, C Gourguechon, T Guiddir, D Lipsker, N Raison-Peyron, N Garcelon, M Cheminant, F Suarez, O Hermine, S Blanche, D Moshous, N Mahlaoui, B Neven, C Bodemer, R Lévy, L Polivka

引用次数: 0

Global Trends in Melanoma Burden: A Comprehensive Analysis from the Global Burden of Disease Study, 1990-2021. 全球黑色素瘤负担趋势：1990-2021 年全球疾病负担研究综合分析》。

IF 12.8 1区医学

Journal of the American Academy of Dermatology Pub Date : 2024-09-27 DOI: 10.1016/j.jaad.2024.09.035

Yulin Sun, Yiming Shen, Qian Liu, Hao Zhang, Lingling Jia, Yi Chai, Hua Jiang, Minjuan Wu, Yufei Li

{"title":"Global Trends in Melanoma Burden: A Comprehensive Analysis from the Global Burden of Disease Study, 1990-2021.","authors":"Yulin Sun, Yiming Shen, Qian Liu, Hao Zhang, Lingling Jia, Yi Chai, Hua Jiang, Minjuan Wu, Yufei Li","doi":"10.1016/j.jaad.2024.09.035","DOIUrl":"https://doi.org/10.1016/j.jaad.2024.09.035","url":null,"abstract":"Background: Melanoma, a significant global health concern, has shown evolving epidemiological trends. Accurate estimation of melanoma's burden is essential for public health strategies and interventions.Objectives: This study aims to estimate the incidence, mortality, and disability-adjusted life years (DALYs) for melanoma, stratified by region, gender, and age group, from 1990 to 2021.Methods: Using data from the Global Burden of Disease (GBD) 2021, we analyzed melanoma incidence, mortality rates, and DALYs in 204 countries from 1990 to 2021. These metrics were age-standardized and stratified by age, sex, Socio-Demographic Index (SDI), region, and country. The estimated annual percentage change (EAPC) was calculated to track temporal trends.Results: Our study shows a substantial global increase in melanoma incidence, with significant disparities between genders and age groups. Higher SDI regions had increased incidence rates, while global mortality declined, likely due to improved detection and treatment.Limitations: The reliance on estimates and models may introduce bias due to variability in disease definitions, diagnostic criteria, and data collection methods.Conclusion: This study underscores the dynamic nature of melanoma's burden and the need for targeted, age-specific, and gender-specific interventions. Continued research is essential to address the growing challenges posed by melanoma.","PeriodicalId":17198,"journal":{"name":"Journal of the American Academy of Dermatology","volume":null,"pages":null},"PeriodicalIF":12.8,"publicationDate":"2024-09-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142349088","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0