Journal of the American Academy of Child and Adolescent Psychiatry最新文献

{"title":"Children's Mental Health Research: Giving Our Nation's Children Our Very Best.","authors":"","doi":"10.1016/j.jaac.2025.05.008","DOIUrl":"https://doi.org/10.1016/j.jaac.2025.05.008","url":null,"abstract":"","PeriodicalId":17186,"journal":{"name":"Journal of the American Academy of Child and Adolescent Psychiatry","volume":"47 1","pages":""},"PeriodicalIF":13.3,"publicationDate":"2025-05-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144130769","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Editorial: Addressing Treatment Inequities in Youth Bipolar Disorder: Key Considerations for Improving Youth Outcomes.","authors":"Danella M Hafeman,Rachel A Vaughn-Coaxum","doi":"10.1016/j.jaac.2025.05.007","DOIUrl":"https://doi.org/10.1016/j.jaac.2025.05.007","url":null,"abstract":"","PeriodicalId":17186,"journal":{"name":"Journal of the American Academy of Child and Adolescent Psychiatry","volume":"47 1","pages":""},"PeriodicalIF":13.3,"publicationDate":"2025-05-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144122030","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Investigating the Shared and Divergent Neuroanatomical Features of Attentional Deficits in Adolescents.","authors":"Mikaela A Rowe,Daniel R Leopold,Amy K Hegarty,Laurie E Cutting,Stephen A Petrill,Lee A Thompson,Erik G Willcutt,Marie T Banich","doi":"10.1016/j.jaac.2025.05.006","DOIUrl":"https://doi.org/10.1016/j.jaac.2025.05.006","url":null,"abstract":"OBJECTIVECognitive disengagement syndrome (CDS), formerly known as sluggish cognitive tempo, is characterized by hypo-activity or slowed behavior, mental fogginess or confusion, excessive sleepiness, and daydreaming. CDS and the predominantly inattentive (IN) presentation of attention-deficit/hyperactivity disorder (ADHD) are frequently co-occurring though separable constructs, each associated with unique constellations of functional impairments. The current study aims to identify their shared and divergent neurobiological correlates.METHODOne hundred eighty-one adolescents (Mage=13.9, SDage=2.2) were recruited from the Colorado Learning Disabilities Research Center twin study. Relationships between attentional symptom dimensions - CDS and IN - and brain volume were examined, controlling for age, sex, and average cortical volume. Procedures were repeated in an outside sample of 292 adolescents (Mage=16.8, SDage=1.4) using a 2-item measure of CDS.RESULTSHigher levels of CDS symptoms were associated with reduced volume within left ventral parietal, temporo-parietal and temporal regions, regions which fall within the ventral attention network. CDS and IN symptoms were significantly associated with gray matter volume in portions of the dorsal attention and default mode networks in opposite directions. Higher levels of CDS symptoms were associated with reduced volume in the left superior and inferior parietal lobules and left frontal portions of the default mode network, whereas IN symptoms were positively correlated with volume in these areas. Several findings were consistent in the outside sample.CONCLUSIONResults from the current study provide novel insights into the neurobiological basis of CDS. They suggest that both CDS and IN symptoms are associated with alterations in brain systems that exert top-down attentional control, though likely for differing reasons. The current study enhances understanding of adolescent attentional deficits.","PeriodicalId":17186,"journal":{"name":"Journal of the American Academy of Child and Adolescent Psychiatry","volume":"45 1","pages":""},"PeriodicalIF":13.3,"publicationDate":"2025-05-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144114267","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Reflections: Demystifying Hope for Children With Traumatic Brain Injury.","authors":"Brason Lee","doi":"10.1016/j.jaac.2025.05.004","DOIUrl":"https://doi.org/10.1016/j.jaac.2025.05.004","url":null,"abstract":"","PeriodicalId":17186,"journal":{"name":"Journal of the American Academy of Child and Adolescent Psychiatry","volume":"54 1","pages":""},"PeriodicalIF":13.3,"publicationDate":"2025-05-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144087491","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Mental Health, Minority Stressors and Resilience Factors Among Early Adolescent Immigrant Youth.","authors":"Nadine Michel,Kate T Tran,Elina Visoki,Mārtiņš M Gataviņš,Christina Ly,Ran Barzilay","doi":"10.1016/j.jaac.2025.05.005","DOIUrl":"https://doi.org/10.1016/j.jaac.2025.05.005","url":null,"abstract":"OBJECTIVEImmigrant youth are a large population in the U.S, yet there are limited studies characterizing mental health and unique individual-level risk and protective factors in early adolescent immigrants. Previous studies reveal variable associations between immigration and psychopathology. We aimed to characterize minority stressors, protective factors, and mental health among adolescent immigrants.METHODWe analyzed data from the Adolescent Brain Cognitive Development Study (N=10,310, mean age=12.9, 52.3% males), which included 227 first-generation immigrant youth (G1, foreign-born), 1,033 second-generation immigrant youth (G2, US-born, both parents born outside US), 489 third-generation immigrant youth (G3, youth and parents US-born, ≥2 grandparents born outside US) and 8,561 non-immigrant youth. We compared exposure to immigration-related risk and protective factors and used linear mixed-effects models to test associations between immigration and its related risk and protective factors (independent variables) with self-reported psychopathology (dependent variable), adjusting for demographics.RESULTSCompared to non-immigrant youth, G1 and G2 youth experienced more immigration-related stressors (discrimination against country of origin, internalized rejection by Americans), and identified less with American culture, yet showed no differences in psychopathology. G1 and G2 youth reported greater identification with their heritage culture, which was associated with less psychopathology. G3 youth were overall similar to controls in all measures. Findings were generally consistent across racial and ethnic groups and when using parent-report psychopathology.CONCLUSIONEarly adolescent first- and second-generation immigrants have resilient mental health despite greater exposure to minority stressors. Findings suggest strong heritage and American cultural identity may be key resilience factors among US immigrant youth.","PeriodicalId":17186,"journal":{"name":"Journal of the American Academy of Child and Adolescent Psychiatry","volume":"42 1","pages":""},"PeriodicalIF":13.3,"publicationDate":"2025-05-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144087490","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The Price and Quality of Methylphenidate Products.","authors":"Aditya Narayan, Ben Teasdale, A J Hudspeth, David Y Light, Jill K Nailor, Kevin Schulman","doi":"10.1016/j.jaac.2025.05.002","DOIUrl":"10.1016/j.jaac.2025.05.002","url":null,"abstract":"<p><strong>Objective: </strong>For many products, generic markets are very mature, with aggressive competition driving down the price of products for manufacturers. Under these conditions, manufacturers may not have an ability to invest in high-quality manufacturing processes.</p><p><strong>Method: </strong>We acquired samples of all available methylphenidate products in immediate-release tablet (IR), extended-release tablet (ERT), and extended-release capsule (ERC) formulations in all available doses from all available labelers listed at one major wholesaler in February 2023. Products were analyzed for variations in dissolution parameters and for the presence of N-nitroso-methylphenidate. Finally, we examined the cost and quality of tested products.</p><p><strong>Results: </strong>All immediate-release methylphenidate products had similar dissolution profiles. For extended-release products, the confidence intervals of the difference factors for 12 of the 24 generic extended-release tablets sampled did not contain the null value, indicating a statistically significant difference in dissolution from the branded product. N-nitroso-methylphenidate, a probable human carcinogen, was detected above regulatory thresholds in generic immediate-release products for 7 of the 15 unique products sampled. N-nitroso-methlyphenidate was detected below regulatory thresholds in extended-release tablets and was not detected above the limit of quantification in extended-release capsules. The average prices for products with and without elevated N-nitroso-methlyphenidate were not significantly different.</p><p><strong>Conclusion: </strong>Independent laboratory testing of generic methylphenidate products found significant product quality concerns. Making product quality transparent could offer the potential to dramatically improve the quality of generic drugs at no additional cost.</p>","PeriodicalId":17186,"journal":{"name":"Journal of the American Academy of Child and Adolescent Psychiatry","volume":" ","pages":""},"PeriodicalIF":9.2,"publicationDate":"2025-05-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144094183","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Editorial: View From Above: Evolving Understanding of Predictors of Relapse and Chronicity in Youth Depression.","authors":"Eric A Youngstrom","doi":"10.1016/j.jaac.2025.05.003","DOIUrl":"https://doi.org/10.1016/j.jaac.2025.05.003","url":null,"abstract":"","PeriodicalId":17186,"journal":{"name":"Journal of the American Academy of Child and Adolescent Psychiatry","volume":"1 1","pages":""},"PeriodicalIF":13.3,"publicationDate":"2025-05-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144087500","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Enduring Mental Health in Childhood and Adolescence: Prevalence, Prediction, and Genetic Architecture.","authors":"Hekmat Alrouh, René Pool, Christel Middeldorp, Meike Bartels","doi":"10.1016/j.jaac.2025.05.001","DOIUrl":"10.1016/j.jaac.2025.05.001","url":null,"abstract":"<p><strong>Objective: </strong>The concept of enduring mental health (EMH) describes a long-term state in which a person does not experience mental disorders. Most people encounter mental health issues at some point; this study investigated the prevalence, predictors, and genetic architecture of EMH across childhood.</p><p><strong>Method: </strong>EMH status was based on longitudinal data from 18,884 Dutch twins assessed at ages 3, 5, 7, 10, and 12 for behavioral and emotional problems. Children were grouped into 3 categories: EMH, some instances of mental health problems, and many instances of mental health problems. Child- and parent-level factors including individual polygenic scores were tested for associations with these 3 categories. A twin model was used to assess the contribution of genetic and environmental factors to EMH.</p><p><strong>Results: </strong>EMH was experienced by 37% of the sample. EMH was associated with parental low and middle education categories (relative risk [95% CI] = 0.77 [0.70-0.86] and 0.88 [0.82-0.95], respectively), child academic achievement (relative risk [95% CI] = 1.07 [1.03,1.12]), and child well-being (relative risk [95% CI] = 1.44 [1.35,1.54]) and was weakly associated with some polygenic scores. The twin model estimated that 54% of the variance in EMH was due to genetic factors.</p><p><strong>Conclusion: </strong>EMH was observed in slightly more than a third of children. Individual differences in EMH were influenced by various sociodemographic factors, mental health-related variables, and genetic predispositions, suggesting that strategies to support EMH will likely require a comprehensive, multifaceted approach.</p><p><strong>Study registration information: </strong>Enduring Mental Health in Childhood and Adolescence: Prevalence, Prediction, and Genetic Architecture; https://osf.io/6fnwg.</p><p><strong>Diversity & inclusion statement: </strong>We worked to ensure sex and gender balance in the recruitment of human participants. We worked to ensure that the study questionnaires were prepared in an inclusive way. We worked to ensure race, ethnic, and/or other types of diversity in the recruitment of human participants. We actively worked to promote sex and gender balance in our author group. One or more of the authors of this paper self-identifies as a member of one or more historically underrepresented racial and/or ethnic groups in science.</p>","PeriodicalId":17186,"journal":{"name":"Journal of the American Academy of Child and Adolescent Psychiatry","volume":" ","pages":""},"PeriodicalIF":9.2,"publicationDate":"2025-05-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144086453","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Understanding Mental Health Across Educational Contexts: Promoting Wellness in Classrooms","authors":"Novita Resti BEd ,&nbsp;Oky Rizkiana Silaban BEd ,&nbsp;Hefni Dwika Sari BEd","doi":"10.1016/j.jaac.2025.04.015","DOIUrl":"10.1016/j.jaac.2025.04.015","url":null,"abstract":"","PeriodicalId":17186,"journal":{"name":"Journal of the American Academy of Child and Adolescent Psychiatry","volume":"64 8","pages":"Pages 961-963"},"PeriodicalIF":9.2,"publicationDate":"2025-05-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144714575","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The Little Prince","authors":"Kim J. Masters MD, MA","doi":"10.1016/j.jaac.2025.04.014","DOIUrl":"10.1016/j.jaac.2025.04.014","url":null,"abstract":"","PeriodicalId":17186,"journal":{"name":"Journal of the American Academy of Child and Adolescent Psychiatry","volume":"64 8","pages":"Pages 959-961"},"PeriodicalIF":9.2,"publicationDate":"2025-05-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144714386","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}