Journal of the American Academy of Child and Adolescent Psychiatry最新文献

IF 9.2 1区医学

Journal of the American Academy of Child and Adolescent Psychiatry Pub Date : 2024-09-06 DOI: 10.1016/j.jaac.2024.08.483

Misty C Richards, Justin Schreiber

引用次数: 0

Dr. Pumariega Replies. 普马里亚加博士回答。

IF 9.2 1区医学

Journal of the American Academy of Child and Adolescent Psychiatry Pub Date : 2024-09-04 DOI: 10.1016/j.jaac.2024.08.489

Andres J Pumariega

引用次数: 0

A Dose-Finding, Biomarker Validation, and Effectiveness Study of Transcranial Magnetic Stimulation for Adolescents With Depression. 经颅磁刺激治疗青少年抑郁症的剂量测定、生物标志物验证和有效性研究。

IF 9.2 1区医学

Journal of the American Academy of Child and Adolescent Psychiatry Pub Date : 2024-09-04 DOI: 10.1016/j.jaac.2024.08.487

Charles P Lewis, Paul A Nakonezny, Ayse Irem Sonmez, Can Ozger, Juan F Garzon, Deniz Doruk Camsari, Deniz Yuruk, Magdalena Romanowicz, Julia Shekunov, Michael J Zaccariello, Jennifer L Vande Voort, Paul E Croarkin

{"title":"A Dose-Finding, Biomarker Validation, and Effectiveness Study of Transcranial Magnetic Stimulation for Adolescents With Depression.","authors":"Charles P Lewis, Paul A Nakonezny, Ayse Irem Sonmez, Can Ozger, Juan F Garzon, Deniz Doruk Camsari, Deniz Yuruk, Magdalena Romanowicz, Julia Shekunov, Michael J Zaccariello, Jennifer L Vande Voort, Paul E Croarkin","doi":"10.1016/j.jaac.2024.08.487","DOIUrl":"https://doi.org/10.1016/j.jaac.2024.08.487","url":null,"abstract":"Objective: Research and clinical application of transcranial magnetic stimulation (TMS) for adolescents with major depressive disorder (MDD) has advanced slowly. Significant gaps persist in our understanding of optimized, age-specific protocols and dosing strategies. This study aimed to compare the clinical effects of 1 Hz versus 10 Hz TMS regimens and examine a biomarker-informed treatment approach with glutamatergic intracortical facilitation (ICF).Method: Participants with moderate-to-severe symptoms of MDD were randomized to 30 sessions of left prefrontal 1 Hz or 10 Hz TMS, stratified by baseline ICF measures. The primary clinical outcome measure was the Children's Depression Rating Scale, Revised (CDRS-R). The CDRS-R and ICF biomarker were collected weekly.Results: Forty-one participants received either 1 Hz (n = 22) or 10 Hz (n = 19) TMS treatments. CDRS-R scores improved compared to baseline in both 1 Hz and 10 Hz groups. For participants with low ICF at baseline, the overall least squares means of CDRS-R scores over the 6-week trial showed that depressive symptom severity was lower for the group treated with 1 Hz TMS than for those who received 10 Hz TMS. There were no significant changes in weekly ICF measurements across the 6 weeks of TMS treatment.Conclusion: Low ICF may reflect optimal glutamatergic N-methyl-d-aspartate (NMDA) receptor activity that facilitates the therapeutic effect of 1 Hz TMS through long-term depression-like mechanisms on synaptic plasticity. The stability of ICF suggests that it is a tonic, trait-like measure of NMDA receptor-mediated neurotransmission, with potential utility to inform parameter selection for therapeutic TMS in adolescents with MDD.","PeriodicalId":17186,"journal":{"name":"Journal of the American Academy of Child and Adolescent Psychiatry","volume":null,"pages":null},"PeriodicalIF":9.2,"publicationDate":"2024-09-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142154406","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

An Imperative to Include Children's Voices in Policy Development: Part of the Solution to Understanding the Impact of Policy on Children's Mental Health. 将儿童的声音纳入政策制定势在必行：了解政策对儿童心理健康影响的部分解决方案。

IF 9.2 1区医学

Journal of the American Academy of Child and Adolescent Psychiatry Pub Date : 2024-09-03 DOI: 10.1016/j.jaac.2024.08.488

Susan dosReis, Rowan Willis-Gorman, Laura N Anderson, Laura Duncan, James A Gaudino, Robin Taylor Wilson, Camille Raynes-Greenow, Katy Bell

引用次数: 0

Neural and Behavioral Correlates of Binge Eating in 9- to 10-Year-Old Children. 9-10 岁儿童暴饮暴食的神经和行为相关性。

IF 9.2 1区医学

Journal of the American Academy of Child and Adolescent Psychiatry Pub Date : 2024-09-03 DOI: 10.1016/j.jaac.2024.07.925

Kathryn E Smith, Eustace Hsu, Tyler B Mason, Shan Luo

{"title":"Neural and Behavioral Correlates of Binge Eating in 9- to 10-Year-Old Children.","authors":"Kathryn E Smith, Eustace Hsu, Tyler B Mason, Shan Luo","doi":"10.1016/j.jaac.2024.07.925","DOIUrl":"https://doi.org/10.1016/j.jaac.2024.07.925","url":null,"abstract":"Objective: This observational study compared children with and without binge eating (BE) on biobehavioral measures of reward responsiveness, inhibitory control, and emotion processes, while accounting for the impact of weight.Method: Children aged 9-10 completed the baseline wave of the Adolescent Brain Cognitive Development study (316 with BE; 7,681 without BE [no-BE]). The prevalence of binge-eating disorder in the BE group was 17.0%; clinically significant internalizing and externalizing symptoms were endorsed by 8.5% and 4.5% of the sample, respectively. The monetary incentive delay (MID) task, stop signal task (SST), and emotional N-back (EN-back) task were administered during neuroimaging. Analyses assessed effects of group (BE vs. no-BE) on task performance and corresponding neural signal in regions of interest (ROIs). Weight status was evaluated as a covariate and as a moderator of effects.Results: Adjusting for weight status, the BE group (vs. no-BE) group showed lower activation during anticipation of reward, specifically large reward (vs. no reward), in the composite ROI consisting of the dorsal striatum, nucleus accumbens, orbital frontal gyrus, amygdala and insula. Groups did not differ significantly in other behavioral or neural outcomes. No interactions between group and weight status were observed.Conclusion: Blunted anticipatory responses to monetary reward were associated with binge eating during peri-adolescence and may play a role in binge eating pathophysiology. Results challenge prior findings in BE that may be confounded by weight, as well as highlight the importance of future prospective research across binge-eating disorder stage of illness.","PeriodicalId":17186,"journal":{"name":"Journal of the American Academy of Child and Adolescent Psychiatry","volume":null,"pages":null},"PeriodicalIF":9.2,"publicationDate":"2024-09-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142145846","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Restoring Decency to the Care of Undomiciled Foster Youth. 恢复对无住所寄养青年的体面照料。

IF 9.2 1区医学

Journal of the American Academy of Child and Adolescent Psychiatry Pub Date : 2024-09-02 DOI: 10.1016/j.jaac.2024.08.484

Candace Broce, Charity A Kemp, Ruwaydah Hasan, Nancy Elizabeth Larson, Anastasia B Alvarado, Jorea Shirley, John N Constantino

引用次数: 0

Systematic Review: Assessment of Blinding Integrity in 161 Randomized Controlled Trials of Attention-Deficit/Hyperactivity Disorder Medications. 系统性综述：161 项注意力缺陷/多动症药物随机对照试验的盲法完整性评估》（Assessment of Blinding Integrity in 161 Randomized Controlled Trials of Attention-Deficit/Hyperactivity Disorder Medications）。

IF 9.2 1区医学

Journal of the American Academy of Child and Adolescent Psychiatry Pub Date : 2024-09-01 DOI: 10.1016/j.jaac.2024.07.926

Guilherme Fusetto Veronesi, Nathan T M Huneke, Mohammad Shah, Samuele Cortese

引用次数: 0

Editorial: Advances in Clinical Science and Practice Need Research on Implicit Bias. 社论：临床科学与实践的进步需要对内隐偏见进行研究。

IF 9.2 1区医学

Journal of the American Academy of Child and Adolescent Psychiatry Pub Date : 2024-08-31 DOI: 10.1016/j.jaac.2024.08.486

Cameron E Hall, Bethany D Michel, Andrew Scott Baron

引用次数: 0

Editorial: Following Offspring of Parents With Bipolar Disorder Into Middle Adulthood: Risk Windows Relevant to Child Psychiatrists. 社论：跟踪双相情感障碍父母的后代进入中年：与儿童精神科医生相关的风险窗口

IF 9.2 1区医学

Journal of the American Academy of Child and Adolescent Psychiatry Pub Date : 2024-08-29 DOI: 10.1016/j.jaac.2024.08.009

Danella M Hafeman

引用次数: 0

Trends in Mental Disorders in Children and Adolescents Receiving Treatment in the State Mental Health System. 在州精神卫生系统接受治疗的儿童和青少年的精神障碍趋势。

IF 9.2 1区医学

Journal of the American Academy of Child and Adolescent Psychiatry Pub Date : 2024-08-26 DOI: 10.1016/j.jaac.2024.08.008

Ramin Mojtabai, Mark Olfson

{"title":"Trends in Mental Disorders in Children and Adolescents Receiving Treatment in the State Mental Health System.","authors":"Ramin Mojtabai, Mark Olfson","doi":"10.1016/j.jaac.2024.08.008","DOIUrl":"https://doi.org/10.1016/j.jaac.2024.08.008","url":null,"abstract":"Objective: To examine recent trends in clinical diagnoses of children and adolescents receiving treatment in publicly funded mental health treatment services in the United States.Method: Data on children and adolescents (≤17 years) receiving treatment from publicly funded mental health treatment services recorded in Mental Health Client Level Data (MH-CLD) 2013-2021 (total number of records=13,684,154) were used to examine temporal trends in the proportion of different child and adolescent psychiatric disorders. Trends were examined overall and in age, sex, racial/ethnic and service strata focusing on community-based programs.Results: The analyses revealed increases in the proportion with anxiety disorders from 9.6% in 2013 to 19.2% in 2021, AOR=2.17, 95% CI=1.85-2.55, p<0.001, trauma- and stressor-related disorders from 22.7% to 27.4%, AOR=1.31, 1.09-1.57, p=0.004, and depressive disorders from 13.4% to 17.0%, AOR=1.20, 1.03-1.41, p=0.04. During this same period, the proportion with bipolar disorders declined almost eight-fold from 10.0% to 1.3%; AOR=0.07, 0.06-0.09, p<0.001. The proportion with conduct disorders also declined from 9.7% to 4.4%; AOR=0.42, 0.32-0.55, p<0.001, and the proportion of oppositional-defiant disorder declined from 11.1% to 7.8%; AOR=0.79, 0.65-0.98, p=0.03. Trends varied across sex, age, and racial/ethnic strata.Conclusion: The composition of childhood psychiatric diagnoses in patients within publicly funded mental health settings changed over the past decade. While some of the trends may reflect changes in diagnostic practices of clinicians, increases in anxiety and depressive disorders parallel trends in the prevalence of these conditions in the general population and highlight a growing need for identifying and treating these conditions in this age group.","PeriodicalId":17186,"journal":{"name":"Journal of the American Academy of Child and Adolescent Psychiatry","volume":null,"pages":null},"PeriodicalIF":9.2,"publicationDate":"2024-08-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142108636","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0