Journal of the American Animal Hospital Association最新文献

Palpation and Computed Tomography as Surrogates for Lymph Node Cytology in Dogs With Sinonasal Cancer. 用触诊和计算机断层扫描代替鼻窦癌犬的淋巴结细胞学检查。

IF 1.1 4区农林科学

Journal of the American Animal Hospital Association Pub Date : 2026-07-01 DOI: 10.5326/JAAHA-MS-7427

Savannah S Simon, Briana X Horne-Reid, Kim R Love, Tracy L Gieger, Michael W Nolan

{"title":"Palpation and Computed Tomography as Surrogates for Lymph Node Cytology in Dogs With Sinonasal Cancer.","authors":"Savannah S Simon, Briana X Horne-Reid, Kim R Love, Tracy L Gieger, Michael W Nolan","doi":"10.5326/JAAHA-MS-7427","DOIUrl":"10.5326/JAAHA-MS-7427","url":null,"abstract":"In dogs with sinonasal cancer, lymph node (LN) metastasis can affect prognosis and treatment. Hence, despite uncertain cost effectiveness, staging often includes regional LN cytology. This retrospective study evaluates how well physical examination and computed tomography (CT) perform as surrogates for regional LN cytology in dogs with sinonasal carcinomas and sarcomas. Dogs were included if their staging included physical examination, CT, and cytology of at least one regional LN. Physical examination parameters and tomographic appearance of the LNs were compared with cytologic descriptions to enable calculation of sensitivity and specificity, plus positive and negative predictive values (PPV and NPV). A total of 150 dogs were included. Fourteen dogs had cytologically confirmed LN metastasis; all 14 had carcinomas. Metastases were detected ipsilaterally in 12 dogs and bilaterally in two dogs. The sensitivity, specificity, PPV, and NPV of LN palpation alone were 71.4, 64, 17, and 96%, respectively; for CT alone, these were 100, 46.3, 16.1, and 100%; and for the combination of palpation and CT, these were 100, 59.5, 23.8, and 100%. Based on these results, detection of a palpably and tomographically normal LN in a dog with sinonasal carcinoma or sarcoma appears sufficient to confidently rule out cytologically detectable metastasis.","PeriodicalId":17185,"journal":{"name":"Journal of the American Animal Hospital Association","volume":"62 4","pages":"143-150"},"PeriodicalIF":1.1,"publicationDate":"2026-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148361373","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Middle Ear Aspiration Cytology via Otoendoscope-Guided Myringotomy Reliably Confirms Tympanokeratoma in Dogs. 耳内窥镜引导下鼓膜切开术中耳穿刺细胞学可靠地证实犬鼓膜角化瘤。

IF 1.1 4区农林科学

Journal of the American Animal Hospital Association Pub Date : 2026-07-01 DOI: 10.5326/JAAHA-MS-7558

Estelle Ferenczi, Andrea Deleani, Amaury Briand, Mélanie Moreira-André, Pascal Prelaud, Diego Rossetti

{"title":"Middle Ear Aspiration Cytology via Otoendoscope-Guided Myringotomy Reliably Confirms Tympanokeratoma in Dogs.","authors":"Estelle Ferenczi, Andrea Deleani, Amaury Briand, Mélanie Moreira-André, Pascal Prelaud, Diego Rossetti","doi":"10.5326/JAAHA-MS-7558","DOIUrl":"10.5326/JAAHA-MS-7558","url":null,"abstract":"The purpose of this study was to determine the correlation between cytology and histology in the diagnosis of canine tympanokeratoma. Dogs that had a middle ear aspiration cytology via otoendoscope-guided myringotomy and a histology of the tympanic bulla content sampled following total ear canal ablation with lateral bulla osteotomy between 2010 and 2024 in one hospital were retrospectively examined. Cytological diagnosis of tympanokeratoma was considered when the sample contained a majority of corneocytes. Thirty-seven ears with a pathological diagnosis of either tympanokeratoma (31/37) or nontympanokeratoma otitis media (6/37) were chosen. Cytology had an accuracy of 78%, a sensitivity of 74%, and a specificity of 100% for diagnosing tympanokeratoma, with negative and positive predictive values of 43 and 100%, respectively. Among ears with histologically confirmed tympanokeratoma, imaging showed lysis and expansion of the tympanic bulla in 45.2 and 12.9%, respectively. Otoendoscopy showed a mass in the horizontal ear canal in 22.6%. Dense opaque pearly yellowish material was sampled from the tympanic cavity in 45.2%. Middle ear aspiration cytology via otoendoscope-guided myringotomy is a useful tool for diagnosing tympanokeratoma and is highly reliable in cases of positive outcomes. However, its capacity to rule out the condition is limited, particularly in infected ears.","PeriodicalId":17185,"journal":{"name":"Journal of the American Animal Hospital Association","volume":"62 4","pages":"169-175"},"PeriodicalIF":1.1,"publicationDate":"2026-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148361410","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Outcomes Following Partial Foot Amputation in Three Cats. 三只猫部分足部截肢后的结果。

IF 1.1 4区农林科学

Journal of the American Animal Hospital Association Pub Date : 2026-07-01 DOI: 10.5326/JAAHA-MS-7568

Maureen A Griffin, Alysha M McGrath, William T N Culp, Celeste Chen

{"title":"Outcomes Following Partial Foot Amputation in Three Cats.","authors":"Maureen A Griffin, Alysha M McGrath, William T N Culp, Celeste Chen","doi":"10.5326/JAAHA-MS-7568","DOIUrl":"10.5326/JAAHA-MS-7568","url":null,"abstract":"Limited data are available regarding partial foot amputation (amputation of two adjacent digits, excluding the first digit) in cats. Three domestic shorthair cats with a median age of 4.2 yr were presented for partial foot amputation between 2010 and 2022. Neoplasia was the indication for partial foot amputation in two cats; one cat underwent partial foot amputation for treatment of a chronic wound. All cats underwent lateral partial foot amputation (excision of digits 4-5) of a thoracic limb. One cat had excisions at the level of the metacarpal-phalangeal joint, and two cats had excision at the level of the distal metacarpal bone. No cats experienced surgical complications intraoperatively. All cats achieved resolution of lameness postoperatively at a median duration of 28 days, although one cat experienced a long-term grade 1 complication associated with a wound that developed where weight bearing occurred. Lateral partial foot amputation of a thoracic limb was overall well tolerated in these three cats, with favorable long-term functional outcomes and manageable complications. Results support the role of partial foot amputation as a viable limb-sparing option in cats, although additional data are needed to assess outcomes for other partial foot amputation locations (medial, central, and pelvic limb) in cats.","PeriodicalId":17185,"journal":{"name":"Journal of the American Animal Hospital Association","volume":"62 4","pages":"183-186"},"PeriodicalIF":1.1,"publicationDate":"2026-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148361346","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Intra-alveolar Adhesive Biomaterial Preserves Ridge Height After Tooth Extraction in Dogs. 牙槽内黏附生物材料保留犬拔牙后牙脊高度。

IF 1.1 4区农林科学

Journal of the American Animal Hospital Association Pub Date : 2026-07-01 DOI: 10.5326/JAAHA-MS-7542

Christopher Snyder, Robert Baratt, Susan Crowder, Jennifer Mathis, Jordan Peters, Mike Brown, Uzma Mhate, Samantha Klausner, Alan Pollack

{"title":"Intra-alveolar Adhesive Biomaterial Preserves Ridge Height After Tooth Extraction in Dogs.","authors":"Christopher Snyder, Robert Baratt, Susan Crowder, Jennifer Mathis, Jordan Peters, Mike Brown, Uzma Mhate, Samantha Klausner, Alan Pollack","doi":"10.5326/JAAHA-MS-7542","DOIUrl":"10.5326/JAAHA-MS-7542","url":null,"abstract":"This multicenter study evaluates the efficacy of a regenerative bone adhesive (RBA), a novel mineral-organic biomaterial, in maintaining alveolar ridge dimensions after extraction of large mandibular teeth in dogs. In a controlled, randomized clinical study, 47 patients with 59 tooth extraction sites across 10 practices were treated by veterinary dental specialists. Study extraction sites had the socket filled with RBA to the rim of the alveolar bone, whereas control sites healed with blood clot only. Computed tomography scans were performed at short-term (6-12 wk) and long-term (6-12 mo) follow-up time points. Analysis revealed statistically significant (P < .001) advantages in RBA-treated sites in both short- and long-term restoration and preservation of residual ridge dimensions. In RBA-treated sites, there was a statistically significant preservation of buccal ridge height, with an almost 2 mm advantage at long-term follow-up (to 12 mo). The biomaterial's adhesive properties, mechanical strength, and osteoconductive nature provide crucial support to the postextraction socket, encouraging bony repair instead of ridge height loss, contributing to this favorable outcome. The results demonstrate that RBA can significantly minimize residual ridge resorption compared to standard extraction alone.","PeriodicalId":17185,"journal":{"name":"Journal of the American Animal Hospital Association","volume":"62 4","pages":"136-142"},"PeriodicalIF":1.1,"publicationDate":"2026-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148361392","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Investigating Multidrug-Resistant Bacteria in Canine Skin Infections at a Veterinary Teaching Hospital. 某兽医教学医院犬皮肤感染多药耐药菌调查。

IF 1.1 4区农林科学

Journal of the American Animal Hospital Association Pub Date : 2026-07-01 DOI: 10.5326/JAAHA-MS-7554

Karin Helena Montin Mills, Sandra N Koch, Melissa Boyd, Sheila M F Torres, Jeffrey B Bender, Annette T Lundberg, Aaron Rendahl

{"title":"Investigating Multidrug-Resistant Bacteria in Canine Skin Infections at a Veterinary Teaching Hospital.","authors":"Karin Helena Montin Mills, Sandra N Koch, Melissa Boyd, Sheila M F Torres, Jeffrey B Bender, Annette T Lundberg, Aaron Rendahl","doi":"10.5326/JAAHA-MS-7554","DOIUrl":"https://doi.org/10.5326/JAAHA-MS-7554","url":null,"abstract":"Identifying multidrug-resistant (MDR) bacteria in veterinary hospitals is crucial for treatment and public health risk mitigation. This study assessed the hospital prevalence of MDR isolates from canine bacterial skin infections, compared prevalence across services and infection types, and identified the most common MDR organisms. Data from hospital records and aerobic skin cultures from August 2021 to November 2024 were reviewed and analyzed. The dataset included 438 cultures from 416 patients and 647 bacterial isolates, and 196 MDR bacteria yielded from 182 samples. The hospital multidrug resistance prevalence was 42% among cultures and 30% among bacterial isolates. The highest multidrug resistance prevalence by service included Primary Care with 68%, Neurology with 62%, Dermatology with 49%, and Surgery with 44%. The MDR bacteria prevalence for superficial surgical site infections was 34%, pyodermas 33%, wounds 30%, masses 28%, and abscesses 13%. Dermatology cultured 72 of 196 (37%) MDR bacteria, Surgery 48 (24%), Emergency and Critical Care 27 (14%), Urgent Care 18 (9%), Primary Care 14 (7%), Neurology eight (4%), Internal Medicine six (3%), and Oncology three (2%). Staphylococcus pseudintermedius was the most common MDR bacteria. These results underscore the need for ongoing surveillance, antimicrobial stewardship, and targeted infection control strategies specific to each veterinary setting.","PeriodicalId":17185,"journal":{"name":"Journal of the American Animal Hospital Association","volume":"62 4","pages":"161-168"},"PeriodicalIF":1.1,"publicationDate":"2026-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148361363","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Doxorubicin as a Rescue Agent for Presumed Neoplastic Disease Causing Acute Intracavitary or Pulmonary Hemorrhage. 阿霉素作为推定的肿瘤疾病引起急性腔内或肺出血的救援剂。

IF 1.1 4区农林科学

Journal of the American Animal Hospital Association Pub Date : 2026-07-01 DOI: 10.5326/JAAHA-MS-7539

Nicholle Jenkins, Sarah Lyles

{"title":"Doxorubicin as a Rescue Agent for Presumed Neoplastic Disease Causing Acute Intracavitary or Pulmonary Hemorrhage.","authors":"Nicholle Jenkins, Sarah Lyles","doi":"10.5326/JAAHA-MS-7539","DOIUrl":"10.5326/JAAHA-MS-7539","url":null,"abstract":"Doxorubicin was used to treat 30 dogs presenting with acute onset of hemorrhage suspected to be caused by neoplastic disease, presumed hemangiosarcoma (HSAa), where surgical intervention was not possible. This study evaluated the effect of doxorubicin on duration of effusion, time to re-effusion, and whether systemic chemotherapy might provide a medical option for patients that do not undergo surgery. When assuming the last point of contact as a date of passing, overall median survival time (MSTb) without censoring was 82 days. Statistical analysis revealed that weight and additional chemotherapy were associated with improved MST. Dogs >15 kg had a more favorable MST of 126 days, compared to dogs <15 kg who had MST of 54 days. Patients treated with an additional chemotherapeutic agent showed a positive association with MST of 156 days as compared to 73 days. Findings revealed that time to re-effusion was extended in patients >15 kg with a median time to re-effusion of 85 days compared to 0.1 days in patients weighing <15 kg. This retrospective study provides a possible alternative to euthanasia or forgoing treatment for patients with acutely hemorrhagic neoplasms where surgery is not pursued.","PeriodicalId":17185,"journal":{"name":"Journal of the American Animal Hospital Association","volume":"62 4","pages":"151-160"},"PeriodicalIF":1.1,"publicationDate":"2026-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148361339","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Surgical Outcomes of Canine Intracranial Meningioma With or Without Radiation. 犬颅内脑膜瘤放疗或不放疗的手术效果。

IF 1.1 4区农林科学

Journal of the American Animal Hospital Association Pub Date : 2026-07-01 DOI: 10.5326/JAAHA-MS-7536

Akihiro Uno, Yuta Nozue, Ryota Iwasaki, Takashi Mori

{"title":"Surgical Outcomes of Canine Intracranial Meningioma With or Without Radiation.","authors":"Akihiro Uno, Yuta Nozue, Ryota Iwasaki, Takashi Mori","doi":"10.5326/JAAHA-MS-7536","DOIUrl":"10.5326/JAAHA-MS-7536","url":null,"abstract":"Meningioma is the most common primary brain tumor in dogs, and recurrence after treatment presents a significant clinical challenge. This retrospective study evaluated prognostic factors in 21 dogs with intracranial meningioma treated with surgical resection alone or with postoperative radiation therapy (RT). Recurrence rate, progression-free survival (PFS), median survival time (MST), and prognostic indicators were assessed. Of the 21 dogs, 13 received adjuvant RT. Local recurrence was noted in six dogs (28%). Overall MST was 845 days, and PFS was 771 days. By treatment group, MST was 886 days for surgery alone and 845 days with RT; PFS was 886 and 531 days, respectively, with no significant statistical difference. Grade 1 tumors and intact male status were associated with favorable outcomes (P < .05). All grade 1 cases (n = 5), treated with surgery alone, showed no recurrence, whereas all recurrences occurred in grade 2 (n = 3) or unknown-grade tumors (n = 3), most receiving radiation. RT was well tolerated but did not show statistically proven efficacy. However, the benefit of postoperative RT could not be determined due to selection bias.","PeriodicalId":17185,"journal":{"name":"Journal of the American Animal Hospital Association","volume":"62 4","pages":"176-182"},"PeriodicalIF":1.1,"publicationDate":"2026-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148361393","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Canine Chylothorax Secondary to Esophageal Foreign Body and Stricture. 犬乳糜胸继发于食管异物和狭窄。

IF 1.1 4区农林科学

Journal of the American Animal Hospital Association Pub Date : 2026-07-01 DOI: 10.5326/JAAHA-MS-7556

Miranda E Senft, Justine A Johnson

引用次数: 0

Primary Immune Thrombocytopenia in 17 Cats: A Case Series. 17只猫原发性免疫性血小板减少症：一个病例系列。

IF 1.1 4区农林科学

Journal of the American Animal Hospital Association Pub Date : 2026-05-01 DOI: 10.5326/JAAHA-MS-7525

Lindsay Courtney, Andrew Woolcock, Hala Ghali, Elizabeth Appleman

{"title":"Primary Immune Thrombocytopenia in 17 Cats: A Case Series.","authors":"Lindsay Courtney, Andrew Woolcock, Hala Ghali, Elizabeth Appleman","doi":"10.5326/JAAHA-MS-7525","DOIUrl":"10.5326/JAAHA-MS-7525","url":null,"abstract":"This retrospective case series describes the clinical features, treatment, and course of disease in 17 cats diagnosed with primary immune thrombocytopenia (pITP). At the time of diagnosis, median age was 4.25 yr (range 7 mo to 16 yr), 15 cats (88.2%) had clinical bleeding, and median platelet count was 10,000/μL (range 5000-50,000/μL). All 17 cats were treated with corticosteroids; cyclosporine was additionally prescribed in 14 cats. The median duration of immunosuppressive therapy was 365 days (range 49-2086 days). Thirteen cats achieved a platelet count > 100,000/µL at a median of 15 days (range 2-207 days) following diagnosis of pITP. Only one cat achieved a full remission. A relapse was documented in 10 cats (59%) at a median of 191 days (range 67-1022 days) after diagnosis and 48 days (range 15-196 days) after immunosuppressive medication was reduced or discontinued. Median survival time was 1067 days (range 49-2516 days). No patient, clinicopathological, or treatment variables were identified to affect 3 and 6 mo survival. This study highlights that clinical bleeding is common in cats with pITP, and despite an initial positive response to therapy, it can be difficult to maintain remission.","PeriodicalId":17185,"journal":{"name":"Journal of the American Animal Hospital Association","volume":"62 3","pages":"115-122"},"PeriodicalIF":1.1,"publicationDate":"2026-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147774841","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Romiplostim Use in Pancytopenia Secondary to Azathioprine Overdose in a Dog. Romiplostim用于治疗犬硫唑嘌呤过量致全血细胞减少症。

IF 1.1 4区农林科学

Journal of the American Animal Hospital Association Pub Date : 2026-05-01 DOI: 10.5326/JAAHA-MS-7513

Jay Pakhawala, Douglas Palma

{"title":"Romiplostim Use in Pancytopenia Secondary to Azathioprine Overdose in a Dog.","authors":"Jay Pakhawala, Douglas Palma","doi":"10.5326/JAAHA-MS-7513","DOIUrl":"10.5326/JAAHA-MS-7513","url":null,"abstract":"A 4 yr old spayed female Kerry blue terrier was presented for pancytopenia secondary to an azathioprine overdose at a referral hospital. The dog was initially prescribed prednisone at 1 mg/kg q 24 hr and azathioprine at 1.6 mg/kg q 24 hr for immune-mediated polyarthropathy. Over 12 wk, the doses were tapered following clinical remission of immune-mediated polyarthropathy. For an unknown period, owner dosing error suggested a drug overdose of azathioprine at 4.8 mg/kg every other day instead of the prescribed 1.6 mg/kg every other day dose. The drugs were discontinued, and the dog presented for bone marrow failure and associated pancytopenia. Romiplostim was administered at 5 μg/kg subcutaneously on three time points (upon initial presentation to the referral facility, day 8 after initial presentation, and day 15 after initial presentation). Repeat bloodwork at the different time points revealed improvement of the pancytopenia. Romiplostim has been used exclusively for thrombocytopenia in dogs; however, literature in humans and mice models suggests that it can influence multiple cell lines. This case report suggests that romiplostim administration can be considered in cases of pancytopenia and may accelerate bone marrow recovery.","PeriodicalId":17185,"journal":{"name":"Journal of the American Animal Hospital Association","volume":"62 3","pages":"123-126"},"PeriodicalIF":1.1,"publicationDate":"2026-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147774810","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0