Journal of the American Animal Hospital Association最新文献

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Leukocyte Esterase and Nitrite Urine Reagent Strip Utility Under Altered Assay Conditions in Dogs. 白细胞酯酶和亚硝酸盐尿试剂条在狗改变测定条件下的效用。
IF 1.3 4区 农林科学
Journal of the American Animal Hospital Association Pub Date : 2022-09-01 DOI: 10.5326/JAAHA-MS-7233
Justin Farris, Melinda S Camus, Paula M Krimer
{"title":"Leukocyte Esterase and Nitrite Urine Reagent Strip Utility Under Altered Assay Conditions in Dogs.","authors":"Justin Farris,&nbsp;Melinda S Camus,&nbsp;Paula M Krimer","doi":"10.5326/JAAHA-MS-7233","DOIUrl":"https://doi.org/10.5326/JAAHA-MS-7233","url":null,"abstract":"<p><p>The study evaluated leukocyte esterase (LE) and nitrite reagent pad usefulness in canine urine using multiple time endpoints and decision thresholds. Whole and sedimented urine samples from 116 client-owned dogs were analyzed with reagent strips from four manufacturers. Results for LE and nitrite were recorded every 30 s up to 150 s using \"trace\" and \"+\" positive thresholds and compared to microscopic urine sediment analysis and culture results. Sedimented urine assessed at 150 s with a \"trace\" positive threshold for LE had significantly or trending higher sensitivity (brand dependent) for pyuria detection compared with manufacturer recommendations. Using these parameters, LE sensitivity and negative likelihood ratio were 66.67-89.47%, and 0.13-0.37, respectively. Following manufacturer recommendations, LE specificity and positive likelihood ratio were 96.91-100% and 17.02-30.63, respectively. Nitrite performance for pyuria and bacteriuria detection was poor for all conditions. LE reagent pads are a useful screening test for pyuria detection using sedimented urine and a \"trace\" positive threshold at 150 s, whereas LE use with traditional manufacturer recommendations is a good confirmatory test for pyuria detection. Nitrite reagent pads are not useful for pyuria or bacteriuria detection.</p>","PeriodicalId":17185,"journal":{"name":"Journal of the American Animal Hospital Association","volume":"58 5","pages":"240-248"},"PeriodicalIF":1.3,"publicationDate":"2022-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40337910","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 2
2022 AAHA Canine Vaccination Guidelines. 2022年犬类接种指南。
IF 1.3 4区 农林科学
Journal of the American Animal Hospital Association Pub Date : 2022-09-01 DOI: 10.5326/JAAHA-MS-Canine-Vaccination-Guidelines
John Ellis, Elizabeth Marziani, Chumkee Aziz, Catherine M Brown, Leah A Cohn, Christopher Lea, George E Moore, Neha Taneja
{"title":"2022 AAHA Canine Vaccination Guidelines.","authors":"John Ellis,&nbsp;Elizabeth Marziani,&nbsp;Chumkee Aziz,&nbsp;Catherine M Brown,&nbsp;Leah A Cohn,&nbsp;Christopher Lea,&nbsp;George E Moore,&nbsp;Neha Taneja","doi":"10.5326/JAAHA-MS-Canine-Vaccination-Guidelines","DOIUrl":"https://doi.org/10.5326/JAAHA-MS-Canine-Vaccination-Guidelines","url":null,"abstract":"<p><p>These guidelines are an update and extension of previous AAHA peer-reviewed canine vaccination guidelines published in 2017. Vaccination is a cornerstone of canine preventive healthcare and one of the most cost-effective ways of maintaining a dog's health, longevity, and quality of life. Canine vaccination also serves a public health function by forming a barrier against several zoonotic diseases affecting dogs and humans. Canine vaccines are broadly categorized as containing core and noncore immunizing antigens, with administration recommendations based on assessment of individual patient risk factors. The guidelines include a comprehensive table listing canine core and noncore vaccines and a recommended vaccination and revaccination schedule for each vaccine. The guidelines explain the relevance of different vaccine formulations, including those containing modified-live virus, inactivated, and recombinant immunizing agents. Factors that potentially affect vaccine efficacy are addressed, including the patient's prevaccination immune status and vaccine duration of immunity. Because animal shelters are one of the most challenging environments for prevention and control of infectious diseases, the guidelines also provide recommendations for vaccination of dogs presented at or housed in animal shelters, including the appropriate response to an infectious disease outbreak in the shelter setting. The guidelines explain how practitioners can interpret a patient's serological status, including maternally derived antibody titers, as indicators of immune status and suitability for vaccination. Other topics covered include factors associated with postvaccination adverse events, vaccine storage and handling to preserve product efficacy, interpreting product labeling to ensure proper vaccine use, and using client education and healthcare team training to raise awareness of the importance of vaccinations.</p>","PeriodicalId":17185,"journal":{"name":"Journal of the American Animal Hospital Association","volume":"58 5","pages":"213-230"},"PeriodicalIF":1.3,"publicationDate":"2022-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40337912","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 36
2022 AAFP/AAHA Antimicrobial Stewardship Guidelines. 2022年AAFP/AAHA抗菌剂管理指南。
IF 1.3 4区 农林科学
Journal of the American Animal Hospital Association Pub Date : 2022-07-01 DOI: 10.5326/1547-3317-58.4.1
Erin Frey, Michael Costin, Jennifer Granick, Matthew Kornya, J Scott Weese
{"title":"2022 AAFP/AAHA Antimicrobial Stewardship Guidelines.","authors":"Erin Frey,&nbsp;Michael Costin,&nbsp;Jennifer Granick,&nbsp;Matthew Kornya,&nbsp;J Scott Weese","doi":"10.5326/1547-3317-58.4.1","DOIUrl":"https://doi.org/10.5326/1547-3317-58.4.1","url":null,"abstract":"Introduction The Antimicrobial Stewardship Guidelines in companion animals are designed to aid practicing veterinarians in choosing appropriate antimicrobial therapy to best serve their patients and minimize the development of antimicrobial resistance and other adverse effects. The Guidelines presented below were developed by an expert task force and provide a recommended framework for judicious antimicrobial use in companion animals.","PeriodicalId":17185,"journal":{"name":"Journal of the American Animal Hospital Association","volume":"58 4","pages":"1-5"},"PeriodicalIF":1.3,"publicationDate":"2022-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40475158","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 7
Mediastinal Serous Cavity Mesothelioma in Two Dogs. 两只犬纵隔浆液腔间皮瘤的研究。
IF 1.3 4区 农林科学
Journal of the American Animal Hospital Association Pub Date : 2022-07-01 DOI: 10.5326/JAAHA-MS-7016
Sean P McDonough, Peter V Scrivani, Karine Gendron, May Tse
{"title":"Mediastinal Serous Cavity Mesothelioma in Two Dogs.","authors":"Sean P McDonough,&nbsp;Peter V Scrivani,&nbsp;Karine Gendron,&nbsp;May Tse","doi":"10.5326/JAAHA-MS-7016","DOIUrl":"https://doi.org/10.5326/JAAHA-MS-7016","url":null,"abstract":"<p><p>The mediastinal serous cavity (MSC)-well documented but seldom recognized in the caudal mediastinum-is embryologically derived from the omental bursa. Mesothelioma arising from the MSC in two dogs is described. Both dogs presented with acute life-threatening hemorrhagic pleural effusion. Contrast computed tomography revealed a large solitary spherical-to-cylindrical tumor in the caudal mediastinum with variably thick, contrast-enhancing walls with lobular to frond-like proliferations that arose circumferentially and projected internally into a single, variably sized, fluid-attenuating lumen. The wall and lumen corresponded to the serous membrane and serous cavity of the MSC. Surgical exploration confirmed that both tumors arose from the mediastinum. Both had similar histologic findings, and special stains were necessary for definitive diagnosis. The tumor was nonresectable in one dog, and it was euthanized intraoperatively. The other survived 7 mo. An MSC mesothelioma should be considered a possible cause of hemothorax in dogs that may be detected on thoracic radiography and computed tomography. Differential diagnoses include esophageal foreign body or neoplasm, paraesophageal diaphragmatic hernia, MCS empyema, and pulmonary adenocarcinoma, with thoracic computed tomography helping to rule out foreign body and diaphragmatic hernia. For confirmed neoplasms, histochemistry and immunohistochemistry should be performed to differentiate between mesothelioma and pulmonary adenocarcinoma.</p>","PeriodicalId":17185,"journal":{"name":"Journal of the American Animal Hospital Association","volume":"58 4","pages":"194-202"},"PeriodicalIF":1.3,"publicationDate":"2022-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40475597","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Associations Between Atopic Dermatitis and Anxiety, Aggression, and Fear-Based Behaviors in Dogs. 狗的特应性皮炎与焦虑、攻击和恐惧行为之间的关系。
IF 1.3 4区 农林科学
Journal of the American Animal Hospital Association Pub Date : 2022-07-01 DOI: 10.5326/JAAHA-MS-7210
Lindsay R McAuliffe, Colleen S Koch, James Serpell, Karen L Campbell
{"title":"Associations Between Atopic Dermatitis and Anxiety, Aggression, and Fear-Based Behaviors in Dogs.","authors":"Lindsay R McAuliffe,&nbsp;Colleen S Koch,&nbsp;James Serpell,&nbsp;Karen L Campbell","doi":"10.5326/JAAHA-MS-7210","DOIUrl":"https://doi.org/10.5326/JAAHA-MS-7210","url":null,"abstract":"<p><p>The goal of this study was to determine if anxiety, aggression, and fear-related behaviors are more common in pruritic dogs with atopic dermatitis than nonpruritic, healthy dogs. One hundred forty-one pruritic dogs >1 yr of age with a clinical diagnosis of atopic dermatitis and a >3 mo history of pruritus were recruited. Dog owners completed a behavioral survey (canine behavioral assessment and research questionnaire) and a pruritus scale (pruritus visual analog scale). Pruritic, atopic dogs showed significant increases in fear- and anxiety-related behaviors as well as aggression compared with a large control group of healthy dogs. Stranger-directed aggression, owner-directed aggression, familiar-dog aggression, dog-directed fear, nonsocial fear, touch sensitivity, excitability, and attention-seeking behaviors were all increased in the study group. Trainability was decreased in the study group. Chronically pruritic dogs experience fear and anxiety and are more likely to display aggression. This is an important welfare issue for these animals. Early recognition of the behavioral derangements that can be associated with chronic pruritic skin disease could allow early intervention with a multidisciplinary approach for these patients, thus improving patient and owner quality of life and long-term treatment outcomes.</p>","PeriodicalId":17185,"journal":{"name":"Journal of the American Animal Hospital Association","volume":"58 4","pages":"161-167"},"PeriodicalIF":1.3,"publicationDate":"2022-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40475159","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
Feline Emphysematous Gastritis in a Cat with Pancreatitis and Secondary Hepatic Lipidosis. 猫肺气肿性胃炎并发胰腺炎和继发性肝脂质病。
IF 1.3 4区 农林科学
Journal of the American Animal Hospital Association Pub Date : 2022-07-01 DOI: 10.5326/JAAHA-MS-7228
Emily Fulton, Gawain Hammond, Francesco Marchesi, Marta Hernández Pérez, Alison E Ridyard
{"title":"Feline Emphysematous Gastritis in a Cat with Pancreatitis and Secondary Hepatic Lipidosis.","authors":"Emily Fulton,&nbsp;Gawain Hammond,&nbsp;Francesco Marchesi,&nbsp;Marta Hernández Pérez,&nbsp;Alison E Ridyard","doi":"10.5326/JAAHA-MS-7228","DOIUrl":"https://doi.org/10.5326/JAAHA-MS-7228","url":null,"abstract":"<p><p>A 7 yr old female neutered domestic shorthair was presented with a 2 mo history of lethargy and hyporexia progressing to anorexia. Initial diagnostics indicated pancreatitis with secondary hepatic lipidosis. Supportive care, including the placement of an esophageal feeding tube, was initiated. The feeding tube was removed traumatically by the cat and thus replaced. The cat acutely deteriorated while hospitalized, developing marked hypersalivation and an obtunded mentation. Radiographs were taken to confirm placement of the feeding tube in case tube dislodgement was contributing to the hypersalivation; results confirmed appropriate positioning and gastric pneumatosis. Despite intensified medical management, the patient suffered cardiopulmonary arrest 7 days after hospital admission. Post-mortem examination confirmed necrotizing gastritis with emphysema alongside segmental mucosal necrosis in the jejunum, focal pancreatic necrosis, and diffuse hepatic lipidosis. Gas in the gastric wall is a rare finding in veterinary medicine and can arise due to gastric pneumatosis or emphysematous gastritis; there are scant reports of either in feline medicine. This report documents a case of emphysematous gastritis in a cat with concurrent pancreatitis and hepatic lipidosis. The cat developed emphysematous gastritis without undergoing gastrointestinal surgery which is currently the only reported feline predis-posing factor for development.</p>","PeriodicalId":17185,"journal":{"name":"Journal of the American Animal Hospital Association","volume":"58 4","pages":"207-212"},"PeriodicalIF":1.3,"publicationDate":"2022-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40475593","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Cystoscopic Abnormalities in Dogs Presented for Episioplasty. 犬外阴成形术的膀胱镜异常。
IF 1.3 4区 农林科学
Journal of the American Animal Hospital Association Pub Date : 2022-07-01 DOI: 10.5326/JAAHA-MS-7177
Alexander Estrin, Dana L Clarke, David E Holt
{"title":"Cystoscopic Abnormalities in Dogs Presented for Episioplasty.","authors":"Alexander Estrin,&nbsp;Dana L Clarke,&nbsp;David E Holt","doi":"10.5326/JAAHA-MS-7177","DOIUrl":"https://doi.org/10.5326/JAAHA-MS-7177","url":null,"abstract":"<p><p>A recessed vulva is a conformational abnormality that predisposes affected dogs to urinary tract infections. An episioplasty can be recommended for correction of this abnormality when medical management of recurrent urinary tract infection fails. The objective of this study was to investigate the type and incidence of urogenital abnormalities visualized by cystoscopy in dogs presenting for episioplasty. Medical records of 29 dogs that presented for an episioplasty and had a concurrent or prior cystoscopy were reviewed. Eleven of the 29 dogs had urogenital abnormalities diagnosed on cystoscopic evaluation, and 1 dog was diagnosed with a urogenital abnormality during vaginal examination while under general anesthesia. Ten of the dogs with urogenital abnormalities had a corrective procedure performed, 8 of which were cystoscopically assisted. Cystoscopy provides the ability to directly visualize the urinary tract and obtain samples for biopsy and culture and facilitates correction of some anatomic abnormalities that may predispose the patient to developing recurrent urinary tract infections. Cystoscopy should be considered as a routine part of a thorough evaluation of the urinary tract in cases presenting for episioplasty.</p>","PeriodicalId":17185,"journal":{"name":"Journal of the American Animal Hospital Association","volume":"58 4","pages":"176-179"},"PeriodicalIF":1.3,"publicationDate":"2022-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40475157","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Diagnosis and Treatment of a Spinal Intraosseous Keratinized Cyst of L1 in a Dog. 犬脊髓L1骨内角化囊肿的诊断与治疗。
IF 1.3 4区 农林科学
Journal of the American Animal Hospital Association Pub Date : 2022-07-01 DOI: 10.5326/JAAHA-MS-7175
Jessica Villm, Rebecca Windsor
{"title":"Diagnosis and Treatment of a Spinal Intraosseous Keratinized Cyst of L1 in a Dog.","authors":"Jessica Villm,&nbsp;Rebecca Windsor","doi":"10.5326/JAAHA-MS-7175","DOIUrl":"https://doi.org/10.5326/JAAHA-MS-7175","url":null,"abstract":"<p><p>An 8 yr old female spayed golden retriever presented for a 3 wk history of progressive pelvic limb ataxia. MRI revealed a well-circumscribed T2-weighted hyperintense, T1-weighted poorly contrast-enhancing extradural mass to the right of the spinal cord at the level of L1 causing severe spinal cord compression. A right-sided hemilaminectomy was performed to remove the mass, and histopathology revealed an intraosseous keratinized cyst. A complete neurologic recovery was made within 2 wk following the surgery. This case illustrates a rare diagnosis and the first case report describing MRI findings and favorable clinical outcome after surgical management of a spinal intraosseous keratinized cyst.</p>","PeriodicalId":17185,"journal":{"name":"Journal of the American Animal Hospital Association","volume":"58 4","pages":"203-206"},"PeriodicalIF":1.3,"publicationDate":"2022-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40475160","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Complete Blood Counts and Blood Smear Analyses in 312 Diabetic Dogs (2007-2017). 312只糖尿病犬的全血细胞计数和血液涂片分析(2007-2017)。
IF 1.3 4区 农林科学
Journal of the American Animal Hospital Association Pub Date : 2022-07-01 DOI: 10.5326/JAAHA-MS-7230
Tanner S Slead, Andrew D Woolcock, J Catharine Scott-Moncrieff, Joanne B Messick, George E Moore
{"title":"Complete Blood Counts and Blood Smear Analyses in 312 Diabetic Dogs (2007-2017).","authors":"Tanner S Slead,&nbsp;Andrew D Woolcock,&nbsp;J Catharine Scott-Moncrieff,&nbsp;Joanne B Messick,&nbsp;George E Moore","doi":"10.5326/JAAHA-MS-7230","DOIUrl":"https://doi.org/10.5326/JAAHA-MS-7230","url":null,"abstract":"<p><p>Diabetes mellitus is a common endocrinopathy in dogs that has been associated with various biochemical changes and comorbid diseases, but hematologic abnormalities have been rarely reported. The aim of this retrospective study was to evaluate complete blood count and blood smear alterations and to describe their relationship with, and incidence of comorbid diseases in, diabetic dogs. Three-hundred twelve diabetic dogs, 286 dogs diagnosed with systemic, nondiabetic illnesses, and 506 healthy dogs were identified during the study period. Groups were compared using contingency tables and logistic regression. Associations between statistically significant complete blood count and blood smear alterations and comorbidities were evaluated using multivariable analysis. High-grade codocytosis and anisocytosis were identified more frequently in diabetic dogs, whereas high-grade reactive lymphocytosis and keratocytosis were identified less frequently (P < .001). Diabetic dogs with high-grade codocytosis had lower red blood cell, hemoglobin, hematocrit and higher white blood cell counts (P < .001). Diabetic ketoacidosis was diagnosed more frequently in diabetic dogs with high-grade codocytosis when compared with those with low-grade codocytosis (P < .001) or when compared with any other cell morphologic alterations. This study suggests that blood smear analysis should be a routine part of the evaluation of diabetic dogs.</p>","PeriodicalId":17185,"journal":{"name":"Journal of the American Animal Hospital Association","volume":"58 4","pages":"180-188"},"PeriodicalIF":1.3,"publicationDate":"2022-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40475596","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 2
Utility of Spleen and Liver Cytology in Staging of Canine Mast Cell Tumors. 脾和肝细胞学在犬肥大细胞瘤分期中的应用。
IF 1.3 4区 农林科学
Journal of the American Animal Hospital Association Pub Date : 2022-07-01 DOI: 10.5326/JAAHA-MS-7006
Megan Brown, Jessica Hokamp, Laura E Selmic, Rachel Kovac
{"title":"Utility of Spleen and Liver Cytology in Staging of Canine Mast Cell Tumors.","authors":"Megan Brown,&nbsp;Jessica Hokamp,&nbsp;Laura E Selmic,&nbsp;Rachel Kovac","doi":"10.5326/JAAHA-MS-7006","DOIUrl":"https://doi.org/10.5326/JAAHA-MS-7006","url":null,"abstract":"<p><p>Abdominal ultrasound with spleen and liver cytology is part of routine staging for canine mast cell tumors (MCTs). However, such tests are associated with increased morbidity and cost. Therefore, the objectives of this study were to determine if spleen cytology was predictive of liver cytology in canine MCTs and if any patient or tumor variables were associated with spleen and/or liver metastasis. Records of dogs with MCTs and cytology of spleen and liver were reviewed. Two hundred five patients were included. Overall, 22 (10.7%) patients had metastasis, with 21 (10.2%) and 13 (6.3%) having spleen and liver metastasis, respectively, and 12 (5.9%) having both. For patients with a positive (or negative) spleen cytology, the odds ratio of having a positive (or negative) liver cytology was 233.49. However, a negative spleen cytology had a higher predictive value (0.99) than a positive cytology (0.54). Finally, the presence of local and systemic signs and tumor size were associated with spleen, liver, and/or spleen or liver metastasis. These results suggest that spleen cytology is predictive of liver cytology in staging of canine MCTs, and increasing tumor size and presence of local or systemic signs are associated with an increased risk of visceral metastasis.</p>","PeriodicalId":17185,"journal":{"name":"Journal of the American Animal Hospital Association","volume":"58 4","pages":"168-175"},"PeriodicalIF":1.3,"publicationDate":"2022-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40475595","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
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