Journal of Research in Pharmacy Practice最新文献

{"title":"Head-to-Head Comparison of Tazarotene and Calcitriol with or without Sequential Therapy in Mild-to-Moderate Psoriasis: A Randomized Open-label Study.","authors":"Jaspreet Kaur Sidhu, Prithpal Singh Matreja, Ashwani Kumar Gupta, Amandeep Singh, Surjit Singh","doi":"10.4103/jrpp.jrpp_10_23","DOIUrl":"10.4103/jrpp.jrpp_10_23","url":null,"abstract":"<p><strong>Objective: </strong>Psoriasis is an autoimmune disease that causes rapid turnover of skin cells. It is a chronic disease that affects a patient's quality of life significantly and frequently requires long-term treatment. The study on sequential therapy with tazarotene 0.1% and calcitriol 0.0003% has not been tried so far; hence, we designed this study to compare the safety and efficacy of sequential therapy with tazarotene 0.1% cream and calcitriol 0.0003% ointment versus monotherapy in mild-to-moderate stable plaque psoriasis (SPP). The objective of this study was to compare the safety and efficacy of topical sequential treatment with tazarotene followed by calcitriol, topical calcitriol followed by tazarotene, tazarotene monotherapy, calcitriol monotherapy, and compare the safety and efficacy of the sequential therapies with monotherapies.</p><p><strong>Methods: </strong>The study was a single center, prospective parallel-group, active control, randomized study of 16 weeks duration (treatment for 8 weeks and follow-up for 16 weeks), randomized to either of the four groups, i.e., tazarotene 0.1% for 4 weeks followed by calcitriol 0.0003% for 4 weeks or calcitriol 0.0003% for 4 weeks followed by tazarotene 0.1% for 4 weeks or tazarotene 0.1% for 8 weeks or calcitriol 0.0003% for 8 weeks. Both tazarotene and calcitriol were applied once daily in all the groups.</p><p><strong>Findings: </strong>There was no significant difference with regard to age and duration of illness among the four treatment groups. Statistically significant improvement was observed in erythema, scaling, and induration scores, and Physician`s global assessment scale at 8 weeks and 16 weeks as compared to baseline in tazarotene - calcitriol, calcitriol - tazarotene, and calcitriol versus tazarotene groups.</p><p><strong>Conclusion: </strong>This study concluded that topical treatment with tazarotene 0.1% and calcitriol 0.003% was efficacious in treating mild-to-moderate SPP as both sequential and monotherapy. However, topical treatment with tazarotene as monotherapy was the least efficacious.</p>","PeriodicalId":17158,"journal":{"name":"Journal of Research in Pharmacy Practice","volume":"12 2","pages":"44-48"},"PeriodicalIF":1.0,"publicationDate":"2024-01-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10923203/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140094270","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Influence of Cigarette Smoking Habit on Clozapine-to-Norclozapine Ratio in Male Patients.","authors":"Roberto Lozano, Carina Bona","doi":"10.4103/jrpp.jrpp_37_23","DOIUrl":"10.4103/jrpp.jrpp_37_23","url":null,"abstract":"<p><strong>Objective: </strong>This study aimed to evaluate the influence of cigarette smoking habit on the clozapine (CLZ)-to-norclozapine (norCLZ) ratio in male patients.</p><p><strong>Methods: </strong>The sample consisted of plasma concentration of CLZ and norCLZ data set. The mean values of CLZ, norCLZ, and CLZ-to-norCLZ, between male patients who smoke versus nonsmokers were compared.</p><p><strong>Findings: </strong>CLZ mean plasma level of 142 ± 80 ng/ml and 305 ± 159 ng/ml, norCLZ mean plasma level of 93 ± 72 ng/ml and 234 ± 62 ng/ml, and mean CLZ-to-norCLZ plasma level ratio of 2.1 ± 1.1 and 1.5 ± 0.5, were obtained respectively for male patients who smoke and nonsmokers.</p><p><strong>Conclusion: </strong>This study has shown a significant decrease in CLZ and norCLZ plasma levels, and an increase in the CLZ-to-norCLZ ratio, in smokers as compared to nonsmokers, due to an increase in the clearance of CLZ and norCLZ by smoking induction of CYP 1A2 and glucuronidation by uridyl glucuronyl transferase enzymes (UGT), mainly UGT 1A4, respectively, as the most probable cause.</p>","PeriodicalId":17158,"journal":{"name":"Journal of Research in Pharmacy Practice","volume":"12 1","pages":"29-31"},"PeriodicalIF":1.0,"publicationDate":"2023-11-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10779687/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139425004","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Toxicoepidemiology of Phosphide Poisoning in the Central Part of Iran.","authors":"Nastaran Eizadi-Mood, Mahnaz Momenzadeh, Masoumeh Sadeghi, Ahmad Yaraghi, Ali Mohammad Sabzghabaee, Sam Alfred","doi":"10.4103/jrpp.jrpp_20_23","DOIUrl":"10.4103/jrpp.jrpp_20_23","url":null,"abstract":"<p><strong>Objective: </strong>Aluminum phosphide (ALP) and zinc phosphide (ZnP) are toxic agrochemical pesticides, which are commonly used as an agent of self-harm in developing countries. Because of high toxicity of phosphides, we evaluated toxico-epidemiology ALP and ZnP poisoning in with respect to outcome.</p><p><strong>Methods: </strong>We performed a cross-sectional study with retrospective chart review including the records for patients admitted due to phosphide poisoning (ALP, ZnP) in a poisoning referral center in Khorshid Hospital, affiliated with Isfahan University of Medial Sciences, Isfahan, Iran. Demographic characteristics, clinical manifestations, outcome (survived or death), and length of hospital stay for the patients were recorded in a data collecting form. Binary backward stepwise logistic regression was used for outcome prediction.</p><p><strong>Findings: </strong>Sixty patients were evaluated in the study. The mean age of patients was 27.61. Thirty-nine patients were men. 96.7% of the patients ingested it intentionally. Most of the patients on admission were conscious (66.7%). Abnormality of EKG was noted in 8.3%. The mortality in ALP and ZnP poisoning was 39.2% and 22.2%, respectively. Serum bicarbonate and base excess in the venous blood gas analysis, systolic blood pressure, and serum sodium level were significantly different between patients with ALP and ZnP poisoning on admission time (<i>P</i> < 0.05). On admission, systolic blood pressure was an important predictive factor for mortality (odds ratio 4.87; 95% confidence interval: 1.5-15.45; <i>P</i> = 0.007).</p><p><strong>Conclusion: </strong>The rate of mortality in phosphide poisoning is high. Knowing predictive factors for mortality help physicians for selecting patients in intensive care unit admission and aggressive treatment.</p>","PeriodicalId":17158,"journal":{"name":"Journal of Research in Pharmacy Practice","volume":"12 1","pages":"21-28"},"PeriodicalIF":1.0,"publicationDate":"2023-11-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10779690/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139425007","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Assessing the Presence of the Joint Commission International Accreditation Requirements in Western Saudi Arabia Hospital Pharmacies: A Cross-sectional Study.","authors":"Ahmed Ibrahim Fathelrahman, Huda Abdullah Almalki, Hanan Rashad Bajunaid, Ghaidaa Khalid Al-Harthi, Manal Omar Aljuaid, Ruqayyah Yahya Majrashi, Mohammed Abdullah Alsuwat","doi":"10.4103/jrpp.jrpp_5_23","DOIUrl":"10.4103/jrpp.jrpp_5_23","url":null,"abstract":"<p><strong>Objective: </strong>The Central Board of Accreditation for Healthcare Institutions (CBAHI) the national Saudi accreditation body accredited most hospitals in Saudi Arabia whereas, the Joint Commission International (JCI) a well-known international accreditation body accredited some hospitals. We assessed Western Saudi Arabia hospital pharmacists' knowledge, opinions, and observations about pharmacy-related JCI accreditation criteria needed for hospitals.</p><p><strong>Methods: </strong>This was a cross-sectional survey-based study conducted among pharmacy personnel working in the Ministry of Health (MOH), Military, and private hospitals in the Makkah region in western Saudi Arabia. The present report represents the findings of descriptive and comparative analyses. Comparative analyses were tested by Student's <i>t</i>-test, analysis of variance, and Chi-square when applicable and a <i>P</i> ≤ 0.05 was considered statistically significant.</p><p><strong>Findings: </strong>One hundred and one pharmacists completed the survey; most of them were from Taif (53.5%) and Jeddah (37.6%) and fewer from Makkah (8.9%). The highest proportions were from MOH (55.4%), private (29.7%), and some from military (14.9%) hospitals. They worked mostly in hospitals accredited with CBAHI (93.1%) than JCI (58.4%) and only (41.6%) worked with quality units. Correct answers on knowledge items ranged from 14.9% to 65.3%. On five-point Likert Scale, they showed supportive ratings on how they perceived the importance of JCI statement provided (overall average score: 3.78) and on how statement criteria are implemented in their hospitals (overall average score: 3.76). Higher proportions of those working in quality units compared to their counterparts were aware that accreditation cycles for JCI and CBAHI are identical (66.7% vs. 55.9%, <i>P</i> = 0.009) and that JCI criteria are more concise than CBAHI (59.5% vs. 52.5%, <i>P</i> = 0.007). Higher proportions of those working in JCI-accredited hospitals compared to their counterparts were aware that JCI criteria are clearer than CBAHI (55.9% vs. 33.3%, <i>P</i> = 0.021) and that JCI criteria are more concise than CBAHI (61% vs. 47.6%, <i>P</i> = 0.012).</p><p><strong>Conclusion: </strong>To a high extent, pharmacists were supportive of JCI criteria and considered the criteria to be implemented in their hospitals. There is a room for improvement to enhance awareness and support of JCI quality criteria among pharmacists.</p>","PeriodicalId":17158,"journal":{"name":"Journal of Research in Pharmacy Practice","volume":"12 1","pages":"1-8"},"PeriodicalIF":1.0,"publicationDate":"2023-11-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10779688/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139424982","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Evaluation of Current Community Pharmacist Practice in Saudi Arabia: A Cross-sectional Study from Patients' Perspective (PART I).","authors":"Abdulmajeed Bajuayfir, Mohammad Alhazmi, Omar Alshareef, Ahmed Rawas, Sumayyah Alsharif, Amal Almasoudi, Ejaz Cheema, Majid Ali","doi":"10.4103/jrpp.jrpp_12_23","DOIUrl":"10.4103/jrpp.jrpp_12_23","url":null,"abstract":"<p><strong>Objective: </strong>This study aimed to evaluate the current practice of community pharmacists from patients' and pharmacists' perspectives in Saudi Arabia. This paper presents the patients' perspective.</p><p><strong>Methods: </strong>A self-administered cross-sectional survey was developed to collect responses from patients in Saudi Arabia from February to April 2021. The questionnaire comprised several statements related to the best practice in community pharmacy. Patients' responses to each statement were scored using a 5-point Likert scale. Higher scores represented the greater extent to which the pharmacists perform the best practice in a community pharmacy setting and vice versa.</p><p><strong>Findings: </strong>The data of 233 participants were included in the analysis. The majority of the participants were female (67%) and Saudi nationals (96%). The minimum mean score was related to the statement: pharmacist discusses with you about herbal medications or vitamin supplements. The maximum mean score was related to the statement: Pharmacist explains to you about the dose of medications and when to take them. Participants who were <20 years old had a significantly highest mean score, whereas those above 40 years old had the least mean score, <i>P</i> = 0.001. Participants from the Eastern region had a significantly highest mean score, compared to South region participants who had the least mean score, <i>P</i> = 0.009.</p><p><strong>Conclusion: </strong>A gap in the current practice and the best practice of community pharmacists was found. The policymakers can utilize these findings to provide targeted professional development opportunities for the practicing community pharmacists to improve the overall service and care for the patients.</p>","PeriodicalId":17158,"journal":{"name":"Journal of Research in Pharmacy Practice","volume":"12 1","pages":"15-20"},"PeriodicalIF":1.0,"publicationDate":"2023-11-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10779689/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139425003","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Prophylaxis Effect of Metronidazole Vaginal Gel in Decreasing the Risk of Surgical Site Infections after Elective Hysterectomy.","authors":"Fahimeh Sabet, Sara Ravan, Azar Danesh Shahraki","doi":"10.4103/jrpp.jrpp_66_21","DOIUrl":"10.4103/jrpp.jrpp_66_21","url":null,"abstract":"<p><strong>Objective: </strong>Infections are an important cause of morbidity and mortality after hysterectomy. Here, we aimed to investigate and evaluate the beneficial effects of metronidazole vaginal gel on the rate of surgical site infections in women undergoing elective abdominal hysterectomy.</p><p><strong>Methods: </strong>This is a randomized prospective, double-blind controlled clinical trial performed in 2020 in Isfahan on 108 candidates for elective hysterectomy. At the beginning of the study, we completed a checklist of the patient's characteristics (patient age, body mass index [BMI], and history of medical conditions such as diabetes, hypertension, anemia, and immune deficiency) and the cause of hysterectomy. All patients were randomized into two groups. The first group received a lubricant vaginal gel single dosage, and the second group received a 0.75% metronidazole vaginal gel single dosage the night before surgery. Patients were visited up to 6 weeks after surgery, and the frequency of infection at the surgical site was determined.</p><p><strong>Findings: </strong>The rates of infection were lower in patients who received metronidazole vaginal gel (5.8%) compared to the control group (11.6%) (<i>P</i> = 0.03). Patients with an estimated blood loss volume of more than 500 mL had higher rates of infection (13.46%) compared to patients with a bleeding volume of fewer than 500 mL (1.9%) (<i>P</i> = 0.001). We also found that patients with diabetes (13.5%) and patients with BMI more than 30 kg/m²(13.5%) had higher rates of infection compared to patients without diabetes (5.8%) and patients with BMI <30 kg/m² (11.5%) (<i>P</i> = 0.001 for both). Patients with higher hospitalization duration had higher infection rates (<i>P</i> = 0.009).</p><p><strong>Conclusion: </strong>Administration of a single dosage of metronidazole vaginal gel before abdominal hysterectomy may reduce surgical site infection and have clinical values.</p>","PeriodicalId":17158,"journal":{"name":"Journal of Research in Pharmacy Practice","volume":"12 1","pages":"9-14"},"PeriodicalIF":1.0,"publicationDate":"2023-11-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10779691/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139425006","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Keep Away from Children's Reach: A Missing Link of Pharmacy Practice Research.","authors":"Mohammed Kanan","doi":"10.4103/jrpp.jrpp_36_23","DOIUrl":"https://doi.org/10.4103/jrpp.jrpp_36_23","url":null,"abstract":"","PeriodicalId":17158,"journal":{"name":"Journal of Research in Pharmacy Practice","volume":"12 1","pages":"32"},"PeriodicalIF":1.0,"publicationDate":"2023-11-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10779692/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139425005","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Knowledge and Compliance of Hydroxychloroquine Prophylaxis for Severe Acute Respiratory Syndrome Coronavirus 2 Infection among Indian Health-Care Workers.","authors":"Rudrashish Haldar,&nbsp;Prabhaker Mishra,&nbsp;Mohan Gurjar,&nbsp;Om Prakash Sanjeev,&nbsp;Vijai Datta Upadhyaya,&nbsp;Ankur Bhatnagar,&nbsp;Dharmendra Bhadauria,&nbsp;Vikas Agarwal","doi":"10.4103/jrpp.jrpp_50_21","DOIUrl":"https://doi.org/10.4103/jrpp.jrpp_50_21","url":null,"abstract":"<p><strong>Objective: </strong>In the initial days of the coronavirus disease 2019 (COVID-19) pandemic, the Indian Council of Medical Research (ICMR) recommended the use of hydroxychloroquine (HCQ) as chemoprophylaxis for health-care workers (HCWs) involved in the care of COVID-19 patients. The present survey aimed to assess the knowledge and compliance of HCQ prophylaxis as per the ICMR recommendations among Indian HCWs during the first wave of the pandemic.</p><p><strong>Methods: </strong>A validated 19-item questionnaire-based survey was distributed to HCWs in our apex tertiary care institute who had completed their duties in the COVID-19 wards to assess the knowledge, attitude, and compliance of all sections of HCWs regarding the ICMR-recommended HCQ prophylaxis. Participation in the survey was voluntary, and anonymity was maintained. Data obtained from the responses were collated and analyzed.</p><p><strong>Findings: </strong>Two hundred and fourteen out of 250 HCWs completed the survey (85.6% response rate). Among 214 participants, 87.9% were below the age of 40 years. 83.2% were aware of the use of HCQ for possible prevention of COVID-19 infection, while only 24.6% took HCQ for 7 weeks as was recommended during that period. The main reasons given by 37.3% of the HCWs for not taking HCQ were their knowledge and research on HCQ, where side effects were prominent. Side effects were reported by 35% of the respondents, of which the most notable was nausea/vomiting (14%) followed by gastritis (12%).</p><p><strong>Conclusion: </strong>The poor compliance with HCQ prophylaxis by HCWs was influenced by their knowledge and research, lack of strong scientific evidence, and drug-associated adverse effects.</p>","PeriodicalId":17158,"journal":{"name":"Journal of Research in Pharmacy Practice","volume":"11 1","pages":"33-39"},"PeriodicalIF":1.0,"publicationDate":"2022-08-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/53/f7/JRPP-11-33.PMC9585800.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40677568","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Community Pharmacists' Services during the COVID-19 Pandemic: A Case Study of Lagos State, Nigeria.","authors":"Ogochukwu U Amaeze,&nbsp;Alexander A Akinola,&nbsp;Ayobami A Aiyeolemi,&nbsp;Folasade O Lawal,&nbsp;Oghogho R Ijomone,&nbsp;Ugochukwu A Mbata","doi":"10.4103/jrpp.jrpp_5_22","DOIUrl":"https://doi.org/10.4103/jrpp.jrpp_5_22","url":null,"abstract":"<p><strong>Objective: </strong>To explore the services community pharmacists in Lagos state provided to their communities during the COVID-19 pandemic.</p><p><strong>Methods: </strong>A cross-sectional survey of community pharmacists drawn from all the Association of Community Pharmacists' zones in Lagos state was done from April to June 2021. Data were collected using a structured, self-reported online questionnaire via Google Forms and were analyzed using descriptive and inferential statistical analysis.</p><p><strong>Findings: </strong>Two hundred and forty community pharmacists participated in the study; the response rate was 80.5%. Patient counseling (99.6%), assessment and treatment of common acute ailments (99.6%), and patient education on hygiene (99.6%) were the most reported services provided by community pharmacists. The COVID-19 infection prevention and control measures most frequently practiced by the pharmacists include cleaning of floors with soap and water (98.4%), provision of hand sanitizers for staff use (97.1%), and taking precautions when handling prescriptions and dispensing drugs (96.7%). Significant barriers to the provision of the services were reduced workforce in the pharmacy, time constraints, and extended working hours. Zinc (98.3%), Vitamin C (97.5%), and ivermectin (95.0%) tablets were the most reported medications for the prevention and treatment of COVID-19 infection.</p><p><strong>Conclusion: </strong>Community pharmacists in Lagos state actively provide pharmacy services and practice various recommended infection prevention and control measures to mitigate the spread of COVID-19 infection in their communities.</p>","PeriodicalId":17158,"journal":{"name":"Journal of Research in Pharmacy Practice","volume":"11 1","pages":"25-32"},"PeriodicalIF":1.0,"publicationDate":"2022-08-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/c8/c0/JRPP-11-25.PMC9585806.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40655552","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Perception of Health Professionals and the General Population Regarding the Use of Antibiotics and Antibiotic Resistance in Puducherry, South India.","authors":"Priyadharsini Raman Palanisamy, Vimala Ananthy, Umamaheswari Subramanian","doi":"10.4103/jrpp.jrpp_8_22","DOIUrl":"10.4103/jrpp.jrpp_8_22","url":null,"abstract":"<p><strong>Objective: </strong>The present study aims to evaluate the awareness of a sample of the general population and health-care professionals regarding the use of antibiotics and antibiotic resistance and identify the factors associated with antibiotic resistance.</p><p><strong>Methods: </strong>This prospective questionnaire-based study was conducted for 3 months, from July to September 2020, in Karaikal, Puducherry (India). The health professionals included doctors in pre- and paraclinical teaching departments (those not involved in clinical practice), laboratory technicians, and PhD students pharmacists. The questionnaire had two parts which health professionals answered, whereas the general population answered only the second part.</p><p><strong>Findings: </strong>About 38.5% of the population reported using antibiotics frequently among the responses obtained. Around 66.5% of the general population usually stop the antibiotic within 1 or 2 days after they feel better, and 11% of the people believed that adding an extra antibiotic would make them better. Among the health professionals, more than 90% responded that self-medication is the major reason for antibiotic resistance and was unsure of the overprescription of antibiotics.</p><p><strong>Conclusion: </strong>The results show variable responses and suggest the need for intervention programs to increase the knowledge among the general population regarding the rational use of antibiotics.</p>","PeriodicalId":17158,"journal":{"name":"Journal of Research in Pharmacy Practice","volume":"11 1","pages":"8-12"},"PeriodicalIF":0.8,"publicationDate":"2022-08-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/20/05/JRPP-11-8.PMC9585803.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40566408","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}