Journal of Research in Clinical Medicine最新文献

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Knowledge, attitudes and practices of intensive care unit nurses towards nutritional care in critically ill patients: A descriptive cross-sectional study 重症监护室护士对危重病人营养护理的知识、态度和实践:一项描述性横断面研究
Journal of Research in Clinical Medicine Pub Date : 2021-10-27 DOI: 10.34172/jrcm.2021.035
A. Mahmoodpoor, S. Sanaie, Fatemeh Momen, Mohammad Ata Pourmoghaddam, S. Saghaleini
{"title":"Knowledge, attitudes and practices of intensive care unit nurses towards nutritional care in critically ill patients: A descriptive cross-sectional study","authors":"A. Mahmoodpoor, S. Sanaie, Fatemeh Momen, Mohammad Ata Pourmoghaddam, S. Saghaleini","doi":"10.34172/jrcm.2021.035","DOIUrl":"https://doi.org/10.34172/jrcm.2021.035","url":null,"abstract":"Introduction: In recent years, there has been a growing concern about the lack of adequate nutrition Knowledge among nurses. Nutrition training in the medical curriculum and for healthcare professionals is contradictory, inadequate, and weak. Nurses are one of the most reliable sources of nutritional information for patients; and yet, little research has been done so far on nurses’ information regarding their important role in nutritional care. Our study is designed to assess the current level of Knowledge, attitudes, and practices of nurses in intensive care units (ICUs). Methods: A four-part questionnaire was used in this study. This descriptive cross-sectional study was conducted from July 2019 to July 2020. The sample size consisted of 110 nurses based on the statistical data obtained from the nursing offices of two hospitals of Tabriz University of medical science including all the nurses working in the ICUs. Thereafter, all questionnaires were re-collected and data were finally analyzed. Results: Results showed that from 110 nurses which were included in this study, 73.6% had high Knowledge, 45.5% had moderate practices, and 58.2% had a positive attitude about nutritional support. Age and level of education had a significant correlation with their knowledge (P=0.005 and P=0.001, respectively). Nursing attitude had a significant correlation with age and the level of education (P=0.03 and P=0.003). And also, nursing practice had a significant relationship with age, work experience in the ICU, and the level of education (P=0.001, P=0.001 and P=0.004, P<0.05). Conclusion: Nurses surveyed in this study had a high knowledge, moderate practice and a positive attitude regarding nutritional care in patients admitted to the ICU.","PeriodicalId":17071,"journal":{"name":"Journal of Research in Clinical Medicine","volume":"42 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-10-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"86842073","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
COVID-19 infection complicated by Guillain-Barre Syndrome: a systematic review of clinical features, pathogenic mechanism, and respiratory failure COVID-19感染合并格林-巴利综合征:临床特征、致病机制和呼吸衰竭的系统综述
Journal of Research in Clinical Medicine Pub Date : 2021-10-26 DOI: 10.34172/jrcm.2021.034
M. Khaki, P. Dehghan, Naghmeh Malekzadeh, M. Khamoushi, Fahimehalsadat Shojaei, Sahar Memar Motazerin, H. Najafi, R. Boostani, G. Malekzadeh, G. Chi
{"title":"COVID-19 infection complicated by Guillain-Barre Syndrome: a systematic review of clinical features, pathogenic mechanism, and respiratory failure","authors":"M. Khaki, P. Dehghan, Naghmeh Malekzadeh, M. Khamoushi, Fahimehalsadat Shojaei, Sahar Memar Motazerin, H. Najafi, R. Boostani, G. Malekzadeh, G. Chi","doi":"10.34172/jrcm.2021.034","DOIUrl":"https://doi.org/10.34172/jrcm.2021.034","url":null,"abstract":"Background: The World Health Organization (WHO) declared a pandemic in March 2020 caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Given the neurotropism feature of the coronavirus and growing number of COVID-19 associated neurological disorders, including Guillain Barre syndrome (GBS), we conducted a systematic review to thoroughly describe the clinical features, diagnostic workup, and clinical outcome of COVID-19 associated GBS in 78 cases. Methods: We identified case reports and case series of COVID-19 associated GBS by conducting a search in the PubMed/MEDLINE and EMBASE databases. We assessed the quality of studies using an appraisal checklist presented by Cochrane Murad et al. Extracted data included demographic characteristics, clinical presentation, diagnostic workup, and outcome. Results: The systematic search yielded a total of 60 articles reporting 78 patients with a diagnosis of COVID-19 associated GBS. The patients were mainly male (65.3%) with an average age of 57 years. The ascending symmetrical paresis was the most common presentation (79.4%), with demyelinating pattern in 54 patients (79.4%). The CSF analysis showed albuminocytologic dissociation in 48 patients (75%). The mortality of COVID-19 associated GBS was estimated as 6.4% attributable to progressive respiratory failure. Conclusion: Given the associated morbidities such as respiratory failure in patients with COVID-19 associated GBS, its timely detection is crucial to prevent poor clinical outcomes. On the other hand, clinicians must be vigilant to identify the clinical findings of SARS-CoV-2 infection in newly diagnosed GBS patients, as this might be a neurological complication of the subclinical viral infection.","PeriodicalId":17071,"journal":{"name":"Journal of Research in Clinical Medicine","volume":"42 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-10-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"82928107","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Ocular wavefront aberrations in acute central serous chorioretinopathy 急性中枢性浆液性脉络膜视网膜病变的眼波前畸变
Journal of Research in Clinical Medicine Pub Date : 2021-10-16 DOI: 10.34172/jrcm.2021.033
Banafsheh Kharrazi Ghadim, N. Taheri, M. Niyousha
{"title":"Ocular wavefront aberrations in acute central serous chorioretinopathy","authors":"Banafsheh Kharrazi Ghadim, N. Taheri, M. Niyousha","doi":"10.34172/jrcm.2021.033","DOIUrl":"https://doi.org/10.34172/jrcm.2021.033","url":null,"abstract":"Background: Central serous chorioretinopathy (CSCR) is a condition of choroidal and retinal pathologies that may affect vision, so we assessed vision by the ocular wavefront in the acute form of CSCR. Methods: This cross-sectional study included 21 cases (16-male, 5-female) of acute onset CSCR was referred to the retina clinic of Nikookari Eye Hospital. Visual acuity and ocular examination with and without pupillary dilation record. Central macular thickness and sub-foveal fluid height of all patients measured by spectral-domain optical coherence tomography (SD-OCT). All of them fulfilled binocular visual function analyzer by Tracy Technology after complete pupillary dilation. The items such as spherical equivalent, total root mean square, total lower-order aberration, total higher-order aberration, defocus, astigmatism, secondary astigmatism, coma, spherical aberration, trefoil, Strehl ratio in point spread function, the average height in the modulation transfer function, and root mean square error registered. Generalized Estimation Equations (GEE) were used to compare two groups of affected CSCR and normal contralateral eyes. Results: The mean uncorrected distance visual acuity in the CSCR eyes is (Decimal Notation) 0.82±0.17 and in the contralateral eyes is 0.95±0.09 (P=0.002). Analysis of macular OCT data CSCR group represents: central foveal thickness 485.9±165.12 μm and mean fluid height 284.3±165.42 μm. The mentioned optical parameters of ocular wavefront aberrations do not have significantly different results in the two groups. Conclusion: Our study showed CSCR reduced uncorrected visual acuity but it did not detect significant ocular wavefront changes in acute CSCR","PeriodicalId":17071,"journal":{"name":"Journal of Research in Clinical Medicine","volume":"67 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-10-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"85672018","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Available Chemical Constituents and Activities of Ganoderma Lucidum (Lingzhi or Red Reishi) Utilizing in Disease Treatment: A mini review 灵芝或红灵芝在疾病治疗中的有效化学成分和活性综述
Journal of Research in Clinical Medicine Pub Date : 2021-10-16 DOI: 10.34172/jrcm.2021.032
T. Vo, T. Vo, T. Vo
{"title":"Available Chemical Constituents and Activities of Ganoderma Lucidum (Lingzhi or Red Reishi) Utilizing in Disease Treatment: A mini review","authors":"T. Vo, T. Vo, T. Vo","doi":"10.34172/jrcm.2021.032","DOIUrl":"https://doi.org/10.34172/jrcm.2021.032","url":null,"abstract":"Medicinal mushrooms are known and used to be nutraceuticals for centuries to enhance health benefits as well as to treat several diseases. Among them, Ganoderma Lucidum (i.e.: G. Lucidum, or red Reishi, or Lingzhi) is appreciated as a medicinal mushroom or significant herbal food for treating diseases, extending life and developing drug. It is detected in different locations, likely contributed confusing concerning its classification. Concomitantly, it has utilized as tea, in alcoholic drinking, and as a complementary medicine to bestow numerous health benefits. Thereby, it is truly important to identify chemical constituents and provide its activities in health benefits regarding these products. Herein, we hope that it is likely a good and right approach for utilizing and encouraging this product, as well as its advantages will be shortly summarized in disease treatments.","PeriodicalId":17071,"journal":{"name":"Journal of Research in Clinical Medicine","volume":"5 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-10-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"85613961","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 4
Treating Umbilical Granuloma with Topical Corticosteroid: A Systematic Review and Meta-analysis 局部皮质类固醇治疗脐肉芽肿:一项系统综述和荟萃分析
Journal of Research in Clinical Medicine Pub Date : 2021-08-05 DOI: 10.34172/jrcm.2021.031
I. Sandinirwan, H. Leo, Hasanah Kahuna, P. P. Karina
{"title":"Treating Umbilical Granuloma with Topical Corticosteroid: A Systematic Review and Meta-analysis","authors":"I. Sandinirwan, H. Leo, Hasanah Kahuna, P. P. Karina","doi":"10.34172/jrcm.2021.031","DOIUrl":"https://doi.org/10.34172/jrcm.2021.031","url":null,"abstract":"Background: Umbilical granuloma so far can be treated with surgery or with silver nitrate. In limited facilities such as in remote areas where the surgeon is limited, pharmacological therapy with silver nitrate or topical steroid can be given. However, treatment with silver nitrate requires medical personnel and has unfavorable adverse effects if done by improper technique. This systematic review aimed to evaluate the effectiveness of topical steroid for treating an umbilical granuloma compared to silver nitrate therapy. Method: The literature search was done using search engines including PubMed, Embase, and Google Scholar. Literature selection was performed with limitations from 2000 to 2020 to get the novelty and written in the English language with a target population of infants less than 6 months were included. To retrieve the articles, topical corticosteroids, topical steroids, and umbilical granuloma were used as keywords. Results: The findings from the included studies show similar sample characteristics. The study conducted by Brodsgaard et al. had an older mean sample age than the study of Ogawa et al. (53.4 vs 31 days). The risk of topical steroid treatment failure on an individual study conducted by Brodsgaard et al. and Ogawa et al. was 3.0 (0.33–27.23, p = 0.33) and 0.94 (0.40–2.21; p = 0.33), respectively. Overall analysis, the risk of treatment failure was 1.09 (0.49–2.43, p = 0.82), there was no difference between the two interventions. Conclusions: One of the umbilical granuloma treatment options that can be considered is topical steroids, such as clobetasol proprionate 0.05% or betamethasone valerate 0.12%. When compared to silver nitrate, topical steroids have a longer therapeutic healing time but with a better safety profile. The non-inferiority study of topical steroids to silver nitrate has not been met yet.","PeriodicalId":17071,"journal":{"name":"Journal of Research in Clinical Medicine","volume":"6 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-08-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"79539245","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
A cutaneous tuberculosis mimic presented with recurrent soft tissue infection: A case report 皮肤结核模拟提出复发性软组织感染:1例报告
Journal of Research in Clinical Medicine Pub Date : 2021-07-31 DOI: 10.34172/jrcm.2021.030
A. Nor Hashimah, Lim Ai Lee, A. Raymond
{"title":"A cutaneous tuberculosis mimic presented with recurrent soft tissue infection: A case report","authors":"A. Nor Hashimah, Lim Ai Lee, A. Raymond","doi":"10.34172/jrcm.2021.030","DOIUrl":"https://doi.org/10.34172/jrcm.2021.030","url":null,"abstract":"Recurrent cellulitis is one of the cutaneous tuberculosis mimickers. As the skin lesion can mimic other skin diseases, the diagnosis can easily be missed especially in immunocompetent patients without any other risk factors. We present a case of a 62-year-old lady with history of right hand extensor tenosynovitis presented with right hand and forearm swelling and pain, associated with fever. Clinically, her right hand and forearm were erythematous with a small nodule at the right elbow. She was treated for recurrent right upper limb cellulitis and thrombophlebitis complicated by septic shock needing several courses of antibiotics. However, she did not show any significant response to the treatment. Multiple septics work up were carried out and all were negative, except aspiration of her right elbow nodule was positive for Mycobacterium tuberculosis. Anti-tuberculous treatment was started but unfortunately, she succumbed due to nosocomial infection.","PeriodicalId":17071,"journal":{"name":"Journal of Research in Clinical Medicine","volume":"44 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-07-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"90312034","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Diagnostic value of serum IgG by Eliza to detecting Mycobacterium tuberculosis, Original Article elisa法检测血清IgG对结核分枝杆菌的诊断价值
Journal of Research in Clinical Medicine Pub Date : 2021-07-24 DOI: 10.34172/JRCM.2021.029
M. Haghdoost, Parisa Alizadeh Nazmi, Hamid Owaysee Osquee
{"title":"Diagnostic value of serum IgG by Eliza to detecting Mycobacterium tuberculosis, Original Article","authors":"M. Haghdoost, Parisa Alizadeh Nazmi, Hamid Owaysee Osquee","doi":"10.34172/JRCM.2021.029","DOIUrl":"https://doi.org/10.34172/JRCM.2021.029","url":null,"abstract":"Introduction: In developing countries, which is an endemic region in terms of tuberculosis, there is an urgent need for fast, accurate, and inexpensive serological testing. The aim of this study was to determine the diagnostic value of patient serum IgG antibodies by ELISA in the diagnosis of Mycobacterium tuberculosis. Method: This case-control study was performed on patients with pulmonary tuberculosis in 2017-2020. After selecting the case (n = 30) and control (n = 30) subjects according to inclusion criteria, their blood samples were obtained and analyzed in the reference laboratory by standard kits for immunoglobulin G against 16, 36, and 40 kDa antigens of mycobacterium tuberculosis. Results: The mean age of the subjects was 47.07 (15.57%). The majority of participants were 46 (51.1%) women. There was no significant difference between the two groups regarding sex and age. serological examination of patients with pulmonary tuberculosis showed 25 positive results and only 4 of the control group had a positive result. Sensitivity, specificity, positive and negative predictive values of serology test were 83.3%, 86.67%, 86.20% and 87.88% respectively. Conclusion: Despite the acceptable sensitivity of the serologic immunoglobulin G test, according to the statement of World health organization (WHO), it did not possess an acceptable specificity. It is recommended that a a wider range of different antigens to be studied also it is essential to evaluate the diagnostic value of the other immunoglobulins inpatient in different stages of the disease.","PeriodicalId":17071,"journal":{"name":"Journal of Research in Clinical Medicine","volume":"8 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-07-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"87890043","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
A short review: Characterization and Heath Effects of Saffron Utilizing in Disease Treatment and Prevention 综述:藏红花的特性及其在疾病防治中的应用
Journal of Research in Clinical Medicine Pub Date : 2021-07-22 DOI: 10.34172/jrcm.2021.028
T. Vo, T. Vo, T. Vo
{"title":"A short review: Characterization and Heath Effects of Saffron Utilizing in Disease Treatment and Prevention","authors":"T. Vo, T. Vo, T. Vo","doi":"10.34172/jrcm.2021.028","DOIUrl":"https://doi.org/10.34172/jrcm.2021.028","url":null,"abstract":"With current technological development, finding and exploring novel chemical compounds from natural material sources can be one of significant purposes for researchers. Especially, saffron is known to be the highest-cost medicinal plant, a high-grade spice, and an outstanding dye. Concomitantly, the final saffron products truly affect much their quality to protect the rights for the consumer, as well as its available healthy benefits can be utilized for treating or preventing various diseases. Herein, the chemical characterization and health effects of saffron are shortly introduced and summarized through treatment and prevention of different diseases (i.e.: cancer, liver, ocular, diabetes, antidepressant, Alzheimer and gastrointestinal diseases), which can favor readers understanding clearly the saffron advantages through this short review. Moreover, it can provide relatively for choosing an effective drying method to maintain the product qualities and facilitate the industrial production of saffron.","PeriodicalId":17071,"journal":{"name":"Journal of Research in Clinical Medicine","volume":"69 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-07-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"87209601","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 2
Assessment of knowledge about Tetanus Diphtheria vaccination of patients with trauma among medical interns: an analytical cross sectional study 对创伤患者破伤风白喉疫苗接种知识的评估:一项分析性横断面研究
Journal of Research in Clinical Medicine Pub Date : 2021-05-23 DOI: 10.34172/jrcm.2021.025
Parham Maroufi, Jafar Ghobadi, Mina Mojarrad, A. Adib
{"title":"Assessment of knowledge about Tetanus Diphtheria vaccination of patients with trauma among medical interns: an analytical cross sectional study","authors":"Parham Maroufi, Jafar Ghobadi, Mina Mojarrad, A. Adib","doi":"10.34172/jrcm.2021.025","DOIUrl":"https://doi.org/10.34172/jrcm.2021.025","url":null,"abstract":"Introduction: Considering the importance of tetanus vaccination in children and adults, recognizing the necessities and priorities of tetanus vaccine injection is essential for health care providers. Medical interns have a crucial role in treating patients at hospitals and as future physicians. This study aims to evaluate Tabriz University of Medical Sciences medical interns' knowledge about tetanus vaccination in patients with trauma. Methods: All interns of Tabriz University of Medical Sciences enrolled in the study. Interns who did not want to participate in the study and those on-call were excluded from the study. Eventually, 250 interns gathered in a conference hall, and a questionnaire of 10 questions was presented to them as a hypothetical traumatic event. Correct and incorrect answers to each question, age, and gender were analyzed. Results: Only in three questions, more than half of the participants answered correctly. These were questions 10, 1, and 2, with 67.2%, 59.2%, and 50.8% of participants answering them correctly, respectively. Also, in 5 questions, less than 20% answered correctly. The maximum overall score was 7. Analysis of these results between the two sexes did not show a significant difference in the number of correct answers and the percentage response to each question. Additionally, age was not indicated as a variable involved in the total score of the participants. Conclusion: Regardless of the age and gender, Tabriz University of Medical Sciences’ medical interns’ knowledge about the precise indications of tetanus prevention in adults and children is poor.","PeriodicalId":17071,"journal":{"name":"Journal of Research in Clinical Medicine","volume":"238 1","pages":"25-25"},"PeriodicalIF":0.0,"publicationDate":"2021-05-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"91544271","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Organ system effects and reinfection of COVID-19: A systematic review 器官系统效应和COVID-19再感染:系统综述
Journal of Research in Clinical Medicine Pub Date : 2021-02-17 DOI: 10.34172/JRCM.2021.006
Inderbir Padda, Nimrat Khehra, U. Jaferi, Dina Mosabbeh, Harshan Atwal, Abbas Musaji, Sufle Bhullar
{"title":"Organ system effects and reinfection of COVID-19: A systematic review","authors":"Inderbir Padda, Nimrat Khehra, U. Jaferi, Dina Mosabbeh, Harshan Atwal, Abbas Musaji, Sufle Bhullar","doi":"10.34172/JRCM.2021.006","DOIUrl":"https://doi.org/10.34172/JRCM.2021.006","url":null,"abstract":"Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and its effects on the organ systems have been summarized in recent literature with predominant pulmonary characteristics as a hallmark of the COVID-19 virus. Considering its accelerated appearance from Wuhan, China, in December 2019, extrapulmonary effects have been reported globally of SARS-CoV-2 involving the central nervous system (CNS), cardiovascular, gastrointestinal, renal, and hematologic systems; thus, the potential mechanisms, pathophysiology, clinical characteristics, management, outcome, and case reports per organ system are summarized in depth. The authors interpreted articles composed of case reports, case-series, meta-analysis, cohort studies, retrospective studies, and narrative reviews focusing on COVID-19 confirmed cases and their effects on the organ systems. Prevalent clinical organ system complexities include pneumonia, acute respiratory distress syndrome (ARDS), pulmonary hypertension, pulmonary embolism, hypertension, cardiac arrhythmias, myocarditis progressing to fulminant myocarditis, anorexia, nausea, vomiting, diarrhea, liver dysfunction, encephalopathy, encephalitis, meningitis, intracerebral hemorrhage, acute kidney injury, and hypercoagulability causing stroke and disseminated intravascular coagulation (DIC). This comprehensive literature review article will help clinicians and researchers gain insight about SARS-CoV-2 and its diverse effects on multiple organ systems involved, therefore help implement prospective management and preventative measures.","PeriodicalId":17071,"journal":{"name":"Journal of Research in Clinical Medicine","volume":"12 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-02-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"89406172","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 5
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