Journal of studies on alcohol. Supplement最新文献_第9页

Diversity of animal models of aggression: their impact on the putative alcohol/aggression link. 动物攻击模式的多样性:它们对假定的酒精/攻击联系的影响。

Journal of studies on alcohol. Supplement Pub Date : 1993-09-01 DOI: 10.15288/jsas.1993.s11.140

P F Brain, R L Miras, M S Berry

引用次数: 7

Adolescents, alcohol and aggression. 青少年，酒精和攻击性。

Journal of studies on alcohol. Supplement Pub Date : 1993-09-01 DOI: 10.15288/jsas.1993.s11.53

G G Milgram

{"title":"Adolescents, alcohol and aggression.","authors":"G G Milgram","doi":"10.15288/jsas.1993.s11.53","DOIUrl":"https://doi.org/10.15288/jsas.1993.s11.53","url":null,"abstract":"Research findings demonstrate that the majority of young adults consume alcohol and that males drink more and more often than females. A significant number of high school seniors and college students have consumed five or more drinks in a row during a 2-week period. High-risk reasons for consumption include: to become intoxicated, to cope with a problem, because of anger and frustration. Social and behavioral consequences of alcohol use affect a number of young adults. Medium to heavy drinkers expect to experience more aggressiveness after drinking. Common risk factors for serious chronic delinquents and frequent users of drugs include psychological and personality factors as well as family conflict, peer factors and school failure. Although research has not determined that alcohol/drugs cause crime or produce the motivation to commit crimes, a relationship between alcohol/drug use and aggressive behavior is apparent. Alcohol plays a significant role in adolescent deaths due to accidents, homicides and suicides, acts of sexual aggression, and criminality. Implications of the research findings are that programs need to be designed with a clear philosophy and realistic goals and they need to target at-risk adolescents. Implementation of promising prevention strategies should take place in the home, school and community, incorporating the influence of parents and peers.","PeriodicalId":17056,"journal":{"name":"Journal of studies on alcohol. Supplement","volume":"11 ","pages":"53-61"},"PeriodicalIF":0.0,"publicationDate":"1993-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.15288/jsas.1993.s11.53","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"19395871","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 84

Alcohol, women and the expression of aggression. 酒精，女人和攻击性的表现。

Journal of studies on alcohol. Supplement Pub Date : 1993-09-01 DOI: 10.15288/jsas.1993.s11.89

E S Gomberg

引用次数: 16

Brain serotonin, type II alcoholism and impulsive violence. 脑血清素，II型酗酒和冲动暴力。

Journal of studies on alcohol. Supplement Pub Date : 1993-09-01 DOI: 10.15288/jsas.1993.s11.163

M Virkkunen, M Linnoila

引用次数: 203

The combination of alprazolam and alcohol on behavioral aggression. 阿普唑仑和酒精对行为攻击的影响。

Journal of studies on alcohol. Supplement Pub Date : 1993-09-01 DOI: 10.15288/jsas.1993.s11.30

A J Bond, J C Silveira

{"title":"The combination of alprazolam and alcohol on behavioral aggression.","authors":"A J Bond, J C Silveira","doi":"10.15288/jsas.1993.s11.30","DOIUrl":"https://doi.org/10.15288/jsas.1993.s11.30","url":null,"abstract":"Forty-eight moderate social drinkers were assigned to one of four treatments: alprazolam (1 mg) and alcohol (0.5 g/kg); alprazolam (1 mg) and placebo drink; placebo capsule and alcohol (0.5 g/kg); and placebo capsule and placebo drink. Breath alcohol concentrations and ratings of mood and intoxication were completed at 90, 150 and 210 minutes post-drug (45, 105 and 165 minutes post-alcohol). Subjects competed in a competitive reaction time task at 105 minutes post-drug during which psychophysiological measures were simultaneously monitored. Active treatments increased sedation and intoxication and the task increased feelings of hostility and anxiety in all subjects. Aggressive responding increased in all groups in response to provocation but some stress response dampening was shown after both alcohol and alprazolam on the psychophysiological measures and after alprazolam on subjective ratings of anxiety. The combination of alprazolam and alcohol increased behavioral aggression more than would have been predicted from the sum of the single effects, confirming clinical reports of behavioral dyscontrol.","PeriodicalId":17056,"journal":{"name":"Journal of studies on alcohol. Supplement","volume":"11 ","pages":"30-9"},"PeriodicalIF":0.0,"publicationDate":"1993-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.15288/jsas.1993.s11.30","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"19395869","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 32

Ethanol prevents desensitization of 5-HT2 receptor-mediated responses consequent to defeat in territorial aggression. 乙醇防止5-HT2受体介导的脱敏反应，导致领土侵略失败。

Journal of studies on alcohol. Supplement Pub Date : 1993-09-01 DOI: 10.15288/jsas.1993.s11.180

D Benjamin, D J Knapp, L A Pohorecky

{"title":"Ethanol prevents desensitization of 5-HT2 receptor-mediated responses consequent to defeat in territorial aggression.","authors":"D Benjamin, D J Knapp, L A Pohorecky","doi":"10.15288/jsas.1993.s11.180","DOIUrl":"https://doi.org/10.15288/jsas.1993.s11.180","url":null,"abstract":"The effect of intruder status in territorial aggression on behavior in the elevated plus-maze, the open field and on 5-HT2 receptor-mediated behaviors was evaluated in male Long-Evans hooded rats. Intruders (350 g) were placed in the home cages of aggressive resident rats (475-600 g) and removed after 20 roll-tumble fights. On the following day, the rats were tested on the elevated plus-maze, and behavior in the open field was evaluated after injection with the 5-HT2/1C receptor agonist, DOI (1.0 mg/kg). The number of headshakes following DOI injection are thought to be an indicator of 5-HT2 receptor function. Although several other stressors were evaluated, only defeat in territorial aggression caused a significant decrement in the number of headshakes following DOI injection. To determine if ethanol (ET) could decrease the behavioral consequences of defeat, the effect of ET (1.25 g/kg) given before and immediately after aggression on behavior 24 hours later was evaluated. Although ET treatment had no effect on the control group that did not experience aggression, the ET treatment attenuated the desensitization of 5-HT2 receptor-mediated responses induced by aggression and severely exacerbated the anxiety-like effects as measured in the elevated plus-maze. These data suggest that (1) 5-HT2 receptor sensitivity decreases as a consequence of defeat, but not after several other stressors; (2) defeat in territorial aggression results in significant anxiety-like effects in the elevated plus-maze 24 hours later; and (3) these anxiety-like effects are exacerbated when ET is given before, and immediately after, the aggression.(ABSTRACT TRUNCATED AT 250 WORDS)","PeriodicalId":17056,"journal":{"name":"Journal of studies on alcohol. Supplement","volume":"11 ","pages":"180-4"},"PeriodicalIF":0.0,"publicationDate":"1993-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.15288/jsas.1993.s11.180","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"19394635","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 6

A longitudinal investigation of alcohol use and aggression in adolescence. 青少年酒精使用与攻击性的纵向调查。

Journal of studies on alcohol. Supplement Pub Date : 1993-09-01 DOI: 10.15288/jsas.1993.s11.62

H R White, J Brick, S Hansell

引用次数: 194

Effects of monoaminergic agonists on alcohol-induced increases in mouse aggression. 单胺能激动剂对酒精诱导小鼠攻击性增加的影响。

Journal of studies on alcohol. Supplement Pub Date : 1993-09-01 DOI: 10.15288/jsas.1993.s11.185

G C Wagner, H Fisher, N Pole, T Borve, S K Johnson

{"title":"Effects of monoaminergic agonists on alcohol-induced increases in mouse aggression.","authors":"G C Wagner, H Fisher, N Pole, T Borve, S K Johnson","doi":"10.15288/jsas.1993.s11.185","DOIUrl":"https://doi.org/10.15288/jsas.1993.s11.185","url":null,"abstract":"Two sets of studies were conducted on alcohol-induced increases in aggression. In the first, the effects of alcohol on target biting and resident-intruder attack were assessed in mice fed a standard diet or one supplemented with 0.5% L-tryptophan. Mice attacked an inanimate target at a high rate following tail shock, an intermediate rate during the intershock interval and a low rate during a tone that preceded the shock. Alcohol increased target biting following shock and during the intershock interval, an effect partially blocked by tryptophan. Resident mice attacked intruders 27.2 +/- 5.3 times per 10-minute session with an average latency of 155 +/- 42 seconds. Alcohol increased the number of attacks and lowered the latency to the first attack. Again, tryptophan partially blocked these effects. Finally, in a second set of mice, the same tryptophan diet was found to potentiate the aggression-reducing effects of fluoxetine and fenfluramine without disrupting motor performance. In the second study, the effects of alcohol administered alone or in combination with tyramine were assessed in the resident-intruder paradigm. Again, it was observed that low doses of alcohol increased the resident attack of intruders. Although this effect was heightened by the co-administration of tyramine, the effect failed to reach statistical significance. These observations are discussed in reference to alcohol-induced increases in offensive and defensive aggression and the possible modulation of this effect by brain monoamines.","PeriodicalId":17056,"journal":{"name":"Journal of studies on alcohol. Supplement","volume":"11 ","pages":"185-91"},"PeriodicalIF":0.0,"publicationDate":"1993-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.15288/jsas.1993.s11.185","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"18694823","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 16

Ethanol-induced enhancement of defensive behavior in different models of murine aggression. 乙醇诱导的防御行为增强在不同模型的小鼠攻击。

Journal of studies on alcohol. Supplement Pub Date : 1993-09-01 DOI: 10.15288/jsas.1993.s11.156

M S Berry

{"title":"Ethanol-induced enhancement of defensive behavior in different models of murine aggression.","authors":"M S Berry","doi":"10.15288/jsas.1993.s11.156","DOIUrl":"https://doi.org/10.15288/jsas.1993.s11.156","url":null,"abstract":"The effects of alcohol on agonistic behavior in mice were studied by introducing an intruder mouse to a resident, alcohol-treated test animal (or saline-injected control). Alcohol (0.1-2.0 g/kg, IP) was administered 20 minutes before testing, and an ethological analysis was made of all behavioral elements shown by the treated animal during a 500-second period. Alcohol did not increase aggression, whether baselines were high, low or experimentally suppressed. Defensive activities, however, were dose-dependently increased, with a threshold dose of 0.5 g/kg or lower in some situations. This suggests that alcohol did not reduce \"anxiety\" or \"fear.\" Aggression tended to decrease, even with doses as low as 0.5 g/kg, which produced BACs of only 25-40 mg/dl at the start of the testing period. With the highest dose, however, aspects of timidity were still increased after 3 hours, but aggression returned to control level after 1 hour, when the BAC was about 250 mg/dl. In other studies, increased aggression has generally been found only with low alcohol doses. This acute tolerance to the anti-aggressive effect of alcohol reported here suggests the possibility of finding pro-aggressive effects at much higher BACs, perhaps more closely simulating the human situation.","PeriodicalId":17056,"journal":{"name":"Journal of studies on alcohol. Supplement","volume":"11 ","pages":"156-62"},"PeriodicalIF":0.0,"publicationDate":"1993-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.15288/jsas.1993.s11.156","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"19394632","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 9

Alcohol, benzodiazepine-GABAA receptor complex and aggression: ethological analysis of individual differences in rodents and primates. 酒精，苯二氮卓- gabaa受体复合物和攻击:啮齿动物和灵长类动物个体差异的行为学分析。

Journal of studies on alcohol. Supplement Pub Date : 1993-09-01 DOI: 10.15288/jsas.1993.s11.170

K A Miczek, E M Weerts, J F DeBold

{"title":"Alcohol, benzodiazepine-GABAA receptor complex and aggression: ethological analysis of individual differences in rodents and primates.","authors":"K A Miczek, E M Weerts, J F DeBold","doi":"10.15288/jsas.1993.s11.170","DOIUrl":"https://doi.org/10.15288/jsas.1993.s11.170","url":null,"abstract":"Research in animals has only recently been successful in reliably mimicking the long-established link between alcohol and heightened aggressive behavior. The present review highlights the large individual differences in the effects of acute low alcohol doses on aggressive behavior in rodent and primate species, paralleling the human condition. Subpopulations of both species show reliable and repeatable enhancement of aggressive behavior when administered low, acute alcohol doses. Statistical analysis of the temporal patterns of aggressive behavior indicate that alcohol prolongs aggressive bouts or \"bursts\" and increases the number of aggressive behaviors within each burst. However, the latency to initiate attack and the time between aggressive bursts are relatively unaltered by alcohol. These alcohol-induced increases in aggression can be potentiated by benzodiazepine agonists and prevented by antagonists. In addition, highly aggressive animals can be differentiated from nonaggressive ones at the GABAA-benzodiazepine receptor complex. These data suggest an important link between alcohol, aggression and the GABAA-benzodiazepine receptor complex.","PeriodicalId":17056,"journal":{"name":"Journal of studies on alcohol. Supplement","volume":"11 ","pages":"170-9"},"PeriodicalIF":0.0,"publicationDate":"1993-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.15288/jsas.1993.s11.170","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"19394634","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 83