Journal of Surgical Research最新文献

{"title":"Letter Regarding: Cryoanalgesia in Patients Undergoing Surgical Stabilization of Rib Fractures: A Comparative Study","authors":"Kishankumar Mahida MD, Snehal Rajendra Jagtap PhD","doi":"10.1016/j.jss.2026.01.033","DOIUrl":"10.1016/j.jss.2026.01.033","url":null,"abstract":"","PeriodicalId":17030,"journal":{"name":"Journal of Surgical Research","volume":"321 ","pages":"Pages 691-692"},"PeriodicalIF":1.7,"publicationDate":"2026-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147618987","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Letter Regarding: Feasibility of Low-Volume Atomized Povidone-Iodine as a Peritoneal Antiseptic in Complicated Appendicitis","authors":"Mustafa Alper Akay MD, Semih Metin MD, Mustafa Enes Özden MD","doi":"10.1016/j.jss.2026.02.034","DOIUrl":"10.1016/j.jss.2026.02.034","url":null,"abstract":"","PeriodicalId":17030,"journal":{"name":"Journal of Surgical Research","volume":"321 ","pages":"Pages 689-690"},"PeriodicalIF":1.7,"publicationDate":"2026-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147609302","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Journal of Surgical Research","authors":"","doi":"10.1016/S0022-4804(26)00258-1","DOIUrl":"10.1016/S0022-4804(26)00258-1","url":null,"abstract":"","PeriodicalId":17030,"journal":{"name":"Journal of Surgical Research","volume":"321 ","pages":"Page iii"},"PeriodicalIF":1.7,"publicationDate":"2026-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147858172","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Letter Regarding: Cryoanalgesia in Patients Undergoing Surgical Stabilization of Rib Fractures: A Comparative Study","authors":"Zhihao Lei PhD","doi":"10.1016/j.jss.2026.01.034","DOIUrl":"10.1016/j.jss.2026.01.034","url":null,"abstract":"","PeriodicalId":17030,"journal":{"name":"Journal of Surgical Research","volume":"321 ","pages":"Pages 693-694"},"PeriodicalIF":1.7,"publicationDate":"2026-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147619047","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Letter Regarding: Prehospital Experience With Left Ventricular Assist Devices","authors":"Chang Meng MD, Jing Sun MM, Guobin Miao MD","doi":"10.1016/j.jss.2025.12.045","DOIUrl":"10.1016/j.jss.2025.12.045","url":null,"abstract":"","PeriodicalId":17030,"journal":{"name":"Journal of Surgical Research","volume":"321 ","pages":"Pages 686-687"},"PeriodicalIF":1.7,"publicationDate":"2026-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147486393","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Textbook Outcomes After Esophagectomy with Gastric Conduit for Cancer: A 2016-2021 National Surgical Quality Improvement Program Analysis","authors":"James J. Park BA ,&nbsp;Giles F. Whalen MD, FACS ,&nbsp;Isabel Cristina M. Emmerick PhD ,&nbsp;Karl F. Uy MD, FACS ,&nbsp;Mark W. Maxfield MD, FACS ,&nbsp;Allison Crawford MS ,&nbsp;Feiran Lou MD, MS, FACS","doi":"10.1016/j.jss.2025.12.036","DOIUrl":"10.1016/j.jss.2025.12.036","url":null,"abstract":"<div><h3>Introduction</h3><div>Textbook outcome (TO) is a composite measure designed to assess the overall short-term outcome of an operation. TO after esophagectomy with gastric conduit using the American College of Surgeons National Surgical Quality Improvement Program (NSQIP) database has not yet been defined.</div></div><div><h3>Methods</h3><div>Records in the NSQIP Esophagectomy Procedure-Targeted database from 2016 to 2021 were analyzed. Patients who underwent elective esophagectomies with gastric conduit for resectable esophageal cancer were included. TO was defined as the absence of anastomotic leak, major complications, positive surgical margins, reintervention ≤30 d postsurgery, prolonged hospital stay (&gt; 21 d), postoperative mortality ≤ 30 d after surgery, and readmission ≤ 30 d after discharge.</div></div><div><h3>Results</h3><div>Of the 6813 patients in the 2016-2021 NSQIP database who underwent esophagectomy, 3733 met study criteria. A total of 2520 (68%) patients achieved TO. The presence of a major complication most frequently prevented the achievement of TO (19%, 692/3733), while the presence of postoperative mortality ≤ 30 d after surgery least frequently prevented achievement of TO (2.3%). The most common complications were organ/space Surgical Site Infection (10%, 372/3733) and unplanned intubation (10%, 366/3733). Of the 493 patients who failed to achieve TO due to one parameter, positive margins (4.7%, 175/3733) and major complications (3.2%, 120/3733) most frequently prevented the achievement of TO. In a multivariable analysis, node stage of 2 or 3 in the TNM staging system, chronic obstructive pulmonary disease, American Society of Anesthesiologists classification of 4, underweight body mass index, Asian race, prolonged operation time, increased preoperative white blood cell, and older age had statistically significant association with failure to achieve TO.</div></div><div><h3>Conclusions</h3><div>In an analysis of the NSQIP database, 68% of cases resulted in TO. Several factors were associated with failure to achieve TO. Further investigations are needed to test if modifying variables like preoperative weight can lead to improved outcomes.</div></div>","PeriodicalId":17030,"journal":{"name":"Journal of Surgical Research","volume":"319 ","pages":"Pages 66-76"},"PeriodicalIF":1.7,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146137384","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Letter Regarding: Predicting Functional Outcomes in Adult Traumatic Brain Injuries Using the Base Deficit, International Normalized Ratio, and Glasgow Coma Scale Score","authors":"Amir Masoud Karimi MD,&nbsp;Ali Hosseini MD","doi":"10.1016/j.jss.2025.11.069","DOIUrl":"10.1016/j.jss.2025.11.069","url":null,"abstract":"","PeriodicalId":17030,"journal":{"name":"Journal of Surgical Research","volume":"319 ","pages":"Pages 213-214"},"PeriodicalIF":1.7,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146132101","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Breast Conserving Therapy is a Safe Option for Women Under 40 Diagnosed With Breast Cancer","authors":"Arith Reyes MD ,&nbsp;Eunice Y. Lee MD, PhD ,&nbsp;Courtney Connelly MD ,&nbsp;Jonathan Wyrick MD ,&nbsp;Roshni Rao MD ,&nbsp;Luona Sun MD ,&nbsp;Bret Taback MD ,&nbsp;Stacy Ugras MD ,&nbsp;Lisa Wiechmann MD","doi":"10.1016/j.jss.2026.01.021","DOIUrl":"10.1016/j.jss.2026.01.021","url":null,"abstract":"<div><h3>Introduction</h3><div>The incidence of breast cancer in young, premenopausal women has increased over time. For women above the age of 40, it is well-established that mastectomy and breast conserving therapy (BCT)—defined as lumpectomy plus radiation— confer similar outcomes in survival, albeit with a higher rate of local recurrence with BCT. The outcomes of mastectomy <em>versus</em> BCT in young women, however, remain unclear. In this study, we evaluate survival and recurrence risk in women under the age of 40 who have undergone mastectomy <em>versus</em> BCT.</div></div><div><h3>Methods</h3><div>We performed a retrospective review of all women diagnosed with breast cancer at the age of 40 or younger between 1995 and 2020 at Columbia University Irving Medical Center. Overall survival and recurrence-free survival were compared for patients undergoing mastectomy and BCT. Data were obtained from an established tumor registry and chart review; multivariate analysis was performed.</div></div><div><h3>Results</h3><div>There were 414 women (average age 35 y) identified who were diagnosed with breast cancer at the age of 40 or younger. The median follow-up was 74 mo. In our cohort, 46% had a family history of breast cancer, 20% carried a <em>BRCA</em> gene pathogenic variant, 28% were nulliparous, and 12% presented with pregnancy-associated breast cancer. Distribution by subtype was: hormone receptor positive (HR+)/ human epidermal growth factor receptor negative (HER2-) in 59%, HER2+ in 21%, and HR-/HER2-/triple negative breast cancer in 20%. The stage at time of diagnosis was as follows: stage 0 (10%); stage 1 (24%); stage 2 (41%); stage 3 (14%), and stage 4 (11%). Neoadjuvant chemotherapy was administered to 42% of women per the standard of care, and 64% (<em>n</em> = 216) underwent mastectomy and 36% (<em>n</em> = 119) underwent BCT. Adjuvant radiation was administered to 68% of women (100% of BCT patients). The most common type of recurrence was distant metastasis (62%) compared with local and locoregional recurrence (38%). There was no statistically significant difference in 5-y overall survival (<em>P</em> = 0.24) and recurrence-free survival (<em>P</em> = 0.09) between BCT and mastectomy. On multivariate analysis , after controlling for age, stage, tumor subtype, and BRCA status, there was no difference in mortality (β = 0.018, <em>P</em> = 0.66) and recurrence (β = −0.069, <em>P</em> = 0.34) between patients who underwent BCT <em>versus</em> mastectomy at the last follow-up.</div></div><div><h3>Conclusions</h3><div>In our cohort with 5-y survival data, BCT is a safe option for women aged 40 y and under who are diagnosed with breast cancer. Despite no survival benefit, young women with breast cancer in our cohort underwent mastectomy more often than lumpectomy. Importantly, most recurrences were distant metastases, suggesting that local therapy choice is less relevant to outcome.</div></div>","PeriodicalId":17030,"journal":{"name":"Journal of Surgical Research","volume":"319 ","pages":"Pages 152-159"},"PeriodicalIF":1.7,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146191342","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Optimizing Thyroid Cytopathology Reports Focused on a Patient-Centered Approach: Mixed Methods Study","authors":"Niranjna Swaminathan MD ,&nbsp;Prudence Wachira BS ,&nbsp;Alexandra Savage BS ,&nbsp;Christopher Wu MD ,&nbsp;K Kerrick Akinola MD ,&nbsp;Daniel Gomez Carrillo MD ,&nbsp;Christian Wells ,&nbsp;Raj Roy MBBS ,&nbsp;Chandler McLeod PhD, MS ,&nbsp;Brenessa Lindeman MD, MEHP ,&nbsp;Jessica Fazendin MD ,&nbsp;Herbert Chen MD ,&nbsp;Andrea Gillis MD, MSPH","doi":"10.1016/j.jss.2026.01.022","DOIUrl":"10.1016/j.jss.2026.01.022","url":null,"abstract":"<div><h3>Introduction</h3><div>Effective comprehension of pathology reports requires adequate health literacy and numeracy. Deficiencies in these skills may hinder communication between patients and providers. This study aimed to assess health literacy and numeracy levels in an endocrine surgery clinic to improve thyroid cytopathology reports from the patients’ perspective.</div></div><div><h3>Methods</h3><div>A prospective study was conducted over 2 mo at a single institution's endocrine surgery clinic. Pre- and post-procedure surveys assessed patient comprehension of thyroid fine-needle aspiration (FNA) cytopathology reports. The pre-procedure survey collected demographics and included 16 items: 12 assessing understanding of thyroid pathology terminology (Pathology Understanding Survey) and four evaluating health literacy and numeracy. The post-procedure survey, administered after patients reviewed their FNA cytopathology reports with the surgeon, included open-ended and multiple-choice questions addressing readability, terminology clarity, layout, and personalization. Qualitative data were thematically coded, and quantitative analyses used chi-square and <em>t</em>-tests.</div></div><div><h3>Results</h3><div>Out of 26 pre-procedure survey participants, most were White (58%), female (65%), and completed post-secondary education (64%). While 73% had high health literacy, 92% had limited numeracy. Higher scores on the cytopathology understanding survey were associated with higher numeracy (<em>P</em> = 0.025) but not prior exposure to thyroid cytopathology reports (<em>P</em> &gt; 0.05). Compared to White respondents, Black respondents had lower numeracy skills (<em>P</em> = 0.048) and older respondents had higher numeracy skills (<em>P</em> = 0.03). There were no demographics associated with higher health literacy (all <em>P</em> ≥ 0.05). Eleven patients completed the post-procedure survey; 82% viewed cytopathology reports favorably but suggested adding visual aids and a glossary. While preferring the existing text volume, patients favored personalized explanations tailored to their findings.</div></div><div><h3>Conclusions</h3><div>Endocrine surgery patients exhibit limited numeracy skills, whereas self-reported health literacy is high. Prior exposure to cytopathology reports was not associated with comprehension, but numeracy was. Patients preferred more personalized reports with visual enhancements, highlighting opportunities to improve cytopathology report design and patient understanding.</div></div>","PeriodicalId":17030,"journal":{"name":"Journal of Surgical Research","volume":"319 ","pages":"Pages 178-184"},"PeriodicalIF":1.7,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146191233","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Incidence and Risk Factors for Venous Thromboembolism in Hemodynamically Unstable Pelvic Fractures","authors":"Rachel A. Holstein MPH ,&nbsp;Courtney H. Meyer MD, MPH ,&nbsp;Olivia Herrmann BS ,&nbsp;Alejandro De Leon Castro MD ,&nbsp;James Walker MD ,&nbsp;Samuel R. Todd MD ,&nbsp;Randi N. Smith MD, MPH ,&nbsp;Jonathan Nguyen DO ,&nbsp;Jason D. Sciarretta MD","doi":"10.1016/j.jss.2026.01.008","DOIUrl":"10.1016/j.jss.2026.01.008","url":null,"abstract":"<div><h3>Introduction</h3><div>Pelvic fractures can cause severe hemorrhage and instability in trauma patients. The association between pelvic fracture morphology, venous thromboembolism (VTE) risk, and clinical outcomes remains unclear. This study evaluates the incidence, risk factors, characteristics, and outcomes of VTE in hemodynamically unstable pelvic fractures.</div></div><div><h3>Methods</h3><div>This retrospective cohort study included adult trauma patients with blunt pelvic ring disruptions and hemorrhagic shock (systolic blood pressure &lt;90 mmHg) admitted to an American College of Surgeons-verified Level I adult trauma center between January 1, 2022 and May 31, 2023. Demographic and clinical data were abstracted from the electronic medical record. The primary outcome was in-hospital VTE. Secondary outcomes included intensive care unit and hospital length of stay (LOS) and mortality.</div></div><div><h3>Results</h3><div>Of 133 patients, 32 (24.1%) developed VTE (4.5% deep vein thrombosis alone, 12.8% pulmonary embolism alone, 6.8% both). VTE was diagnosed a median of 7 d after admission. Nearly all patients received early chemoprophylaxis (median initiation hospital day 1), with no differences in timing by VTE status or fracture pattern (<em>P</em> &gt; 0.05). Fracture morphology was not independently associated with VTE. VTE was associated with longer intensive care unit LOS (11.5 <em>versus</em> 5.0 d, <em>P</em> &lt; 0.001) and hospital LOS (20.5 <em>versus</em> 17.0 d, <em>P</em> = 0.028), though mortality did not differ. In multivariable regression, no independent associations were found between VTE and age, sex, body mass index, or injury severity score.</div></div><div><h3>Conclusions</h3><div>VTE was common despite early chemoprophylaxis. Fracture morphology did not independently predict VTE. Early VTE timing underscores the need for vigilant surveillance and uninterrupted prophylaxis. Prospective studies are needed.</div></div>","PeriodicalId":17030,"journal":{"name":"Journal of Surgical Research","volume":"319 ","pages":"Pages 47-57"},"PeriodicalIF":1.7,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146132147","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}