{"title":"Renal dysfunction in pulmonary cancer patients; a mini-review","authors":"H. Nasri","doi":"10.34172/jre.2023.25103","DOIUrl":"https://doi.org/10.34172/jre.2023.25103","url":null,"abstract":"Early detection of renal dysfunction can help clinicians plan optimal treatment strategies to manage the underlying cause, such as a paraneoplastic syndrome or tumor lysis syndrome. Effective management of renal dysfunction can help improve overall clinical outcomes of the lung cancer patient.","PeriodicalId":16964,"journal":{"name":"Journal of Renal Endocrinology","volume":"92 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"78368139","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Muscle-kidney crosstalk; the role of myokines","authors":"M. Moonesan","doi":"10.34172/jre.2023.25129","DOIUrl":"https://doi.org/10.34172/jre.2023.25129","url":null,"abstract":"Muscle-kidney crosstalk refers to the communication and interaction between skeletal muscle tissue and the kidneys. One important aspect of this crosstalk is the role of myokines. Myokines are a class of bioactive molecules that are released by contracting skeletal muscles. They act as signaling molecules that can mediate communication between muscle tissue and various target organs, including the kidneys. Myokines are involved in regulating various physiological processes and have been shown to have both local and systemic effects.","PeriodicalId":16964,"journal":{"name":"Journal of Renal Endocrinology","volume":"53 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"80799294","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Anna Ghorbani, M. Soltanian, Farzaneh Barkhordari Ahmadi, Mahsa Asadollahi Hamedani, M. Belali Kharaji, Najmeh Parsai, Amirhossein Khoshghadam
{"title":"Onconephropathology; an emerging field of medicine","authors":"Anna Ghorbani, M. Soltanian, Farzaneh Barkhordari Ahmadi, Mahsa Asadollahi Hamedani, M. Belali Kharaji, Najmeh Parsai, Amirhossein Khoshghadam","doi":"10.34172/jre.2023.25117","DOIUrl":"https://doi.org/10.34172/jre.2023.25117","url":null,"abstract":"is the study of the interaction between cancer and kidney disease. This field also focuses the ways in which kidney disease can influence cancer prognosis and treatment. Onconephropathology is a multidisciplinary field that involves collaboration between nephrologists, oncologists, pathologists, and other healthcare professionals. Onconephropathology is a rapidly evolving field, since ongoing research is necessary to better understand the complex interactions between kidney disease and cancer.","PeriodicalId":16964,"journal":{"name":"Journal of Renal Endocrinology","volume":"1997 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"88166577","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Sina Bakhshaei, Bina Bakhshaei, Rastina Mehrani, Sina Neshat, Zeinab Rezvani, Sara Dehghan, H. Mardanparvar, M. Momenzadeh
{"title":"Allopurinol and renal impairment; as review on current findings","authors":"Sina Bakhshaei, Bina Bakhshaei, Rastina Mehrani, Sina Neshat, Zeinab Rezvani, Sara Dehghan, H. Mardanparvar, M. Momenzadeh","doi":"10.34172/jre.2023.25081","DOIUrl":"https://doi.org/10.34172/jre.2023.25081","url":null,"abstract":"Hyperuricemia is described as a serum uric acid level more than 6.0 mg/dL. It is demonstrated by basic research and clinical studies, which the elevation of uric acid level may change the renal histology and function by developing acute and chronic kidney diseases (CKDs), diabetic nephropathy and end-stage renal disease (ESRD). There is no doubt about a significant relationship between uric acid and renal impairment. However, the details of this correlation, especially; between uric acid and renal failure, are discussable. Renal vasoconstriction, antiangiogenic properties, endothelial dysfunction, proinflammatory properties, renal fibrosis, pro-oxidative properties, and alteration of renal autoregulation are the most common mechanisms, which approve the association between uric acid and renal impairment. Allopurinol administration for CKD treatment in patients with gout is one of the most discussable challenges. It should be investigated whether allopurinol can diminish the deterioration of the glomerular filtration rate (GFR) in CKD patients who are at risk of ESRD. Some previous studies reported that allopurinol decreases the CKD incident risk, but others could not confirm this association. The benefit or risks of allopurinol in different stages of CKD, dialysis, and renal transplant are discussed in this study.","PeriodicalId":16964,"journal":{"name":"Journal of Renal Endocrinology","volume":"58 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"76346251","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Sajad Salehipour, Hanieh Molaee, Fatemeh Kord Salarzehi, H. Sarani, Mohamad Khaledi, Reyhaneh Sadeghian, Rokhsare Zareie, Nahid Mir, Mahsa Asadollahi Hamedani
{"title":"Kidney stones incidence and related factors in hemodialysis patients: a multi-center study of Iran southeast population","authors":"Sajad Salehipour, Hanieh Molaee, Fatemeh Kord Salarzehi, H. Sarani, Mohamad Khaledi, Reyhaneh Sadeghian, Rokhsare Zareie, Nahid Mir, Mahsa Asadollahi Hamedani","doi":"10.34172/jre.2023.25102","DOIUrl":"https://doi.org/10.34172/jre.2023.25102","url":null,"abstract":"Introduction: In previous studies, kidney stones was reported as a common complication in general populations. Objectives: This study aimed to evaluate kidney stone incidence and related factors in hemodialysis patients. Patients and Methods: This descriptive-analytical study was conducted on 284 hemodialysis patients in the Zahedan. Demographic and clinical data were collected. The incidence rate of kidney stone was calculated. The correlation between kidney stone incidence with predicting factors was explored by multivariate logistic regression. Results: Results demonstrated that most patients were male, with a mean age of 48.81 ± 16.84 years. The correlation between kidney stone incidence with gender, race, smoking, and blood group was not significant (P > 0.05); however, its correlation with diabetes mellitus, urinary tract infection, age, and body mass index (BMI) was significant (P < 0.05). The kidney stone incidence rate was 23.24%, while diabetes mellitus, urinary tract infection, older age, and higher BMI were the most common predictors. Conclusion: Diabetes mellitus, urinary tract infection, older age, and higher BMI were the common predictors for kidney stone incidence in hemodialysis patients. Identifying kidney stone incidence predictors in patients with hemodialysis can be helping in lower complications.","PeriodicalId":16964,"journal":{"name":"Journal of Renal Endocrinology","volume":"88 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"85633855","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Correlation of flow cytometry and bone marrow biopsy in marrow involvement of lymphoma patients","authors":"Pardis Nematollahi, Behnoosh Mohammadi Jazi, Negin Forouzandeh","doi":"10.34172/jre.2023.25087","DOIUrl":"https://doi.org/10.34172/jre.2023.25087","url":null,"abstract":"Introduction: Non-Hodgkin’s lymphomas (NHLs) are hematolymphoid malignancies. Bone marrow biopsy (BMB) is performed for staging. BMB findings are an important indicator of prognosis and treatment planning. In this study, we compared flow cytometry and BMB in marrow involvement of lymphoma patients. Objectives: This study aimed to compare the frequency of involvement in bone marrow in flow cytometry and biopsy, compare the frequency of involvement in bone marrow in flow cytometry based on gender, compare frequency of bone marrow involvement in biopsy based on gender, compare mean age between two groups with bone marrow involvement and without bone marrow involvement in biopsy, compare mean age between two groups struggling with bone marrow involvement and without bone marrow involvement in flow cytometry, and compare mean ages between all genders struggling with bone marrow involvement and without bone marrow involvement in flow cytometry and biopsy. Patients and Methods: This study was cross-sectional, and the population included all patients affected by NHL, which bone marrow flow cytometry and biopsy performed for disease staging referred to Seyed Al-Shohada hospital affiliated with Isfahan University of medical sciences during 2016-2020. Four color flow cytometry devices (PARTEC CyFlow Space, Germany) with EXBIO antibody kits (Spain) were used. Results: In this study, the number of samples was 107, of which 68 (63.6%) were male, and the mean (standard deviation) of the total age was 40.87 (18.98) years. All samples were diagnosed as lymphoma and were examined by bone marrow flow cytometry and biopsy. Flow cytometry frequency of bone marrow involvement was 14 (13.1%), and biopsy frequency of bone marrow involvement was 22 (20.6%). In 97 cases (90.6%), the diagnosis of both methods was the same. Nine patients (8.4%) had bone marrow involvement in biopsy only, and one case (1%) had bone marrow involvement in flow cytometry only. As a result, bone marrow involvement in patients with lymphoma who participated in this project is about 21.5%. Conclusion: We concluded that evaluation of bone marrow involvement using combined methods is more efficient than biopsy or flow cytometry alone. We also recommended physicians use both methods at the same time.","PeriodicalId":16964,"journal":{"name":"Journal of Renal Endocrinology","volume":"56 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"90985515","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Mohammad Reza Ghaffarzadeh Esfahani, Sina Bakhshaei, Rastina Mehrani
{"title":"Screening patients with type 1 diabetes and hypothyroidism for related autoimmune diseases","authors":"Mohammad Reza Ghaffarzadeh Esfahani, Sina Bakhshaei, Rastina Mehrani","doi":"10.34172/jre.2023.25127","DOIUrl":"https://doi.org/10.34172/jre.2023.25127","url":null,"abstract":"This review critically discusses the importance of screening patients with type 1 diabetes and hypothyroidism for related autoimmune diseases. It provides insights into the prevalence of thyroid disorders and diabetes mellitus, as well as the connection between T1D and hypothyroidism. The review also highlights the benefits of early detection and the implications for health policy, practice, research, and medical education. Overall, this article provides valuable information for healthcare providers on how to screen patients for related autoimmune diseases and provide them with the best possible care.","PeriodicalId":16964,"journal":{"name":"Journal of Renal Endocrinology","volume":"23 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135653424","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Mehrdad Rahmanian, Samira Moradi, Maryam Raziee Fijani, Ayda Hasanpour Dehkordi, Sara Dehghan, Erfan Ghanbarzadeh, E. Zaremoghadam, H. Mardanparvar, Zohreh Mohagheghi
{"title":"Risk of lactic acidosis following injection of iodinated contrast medium for individuals with type 2 diabetes receiving metformin during angiography","authors":"Mehrdad Rahmanian, Samira Moradi, Maryam Raziee Fijani, Ayda Hasanpour Dehkordi, Sara Dehghan, Erfan Ghanbarzadeh, E. Zaremoghadam, H. Mardanparvar, Zohreh Mohagheghi","doi":"10.34172/jre.2023.25083","DOIUrl":"https://doi.org/10.34172/jre.2023.25083","url":null,"abstract":"Lactic acidosis (LA) due to metformin prescription is a rare condition; however, this circumstance is accompanied by a very high rate of death (≥50%). Accumulation of metformin alone is hardly a cause of LA, and more than 90% of patients with metformin-associated LA had a hypoxic condition that could prompt hazards of LA. LA related to this drug occurs after iodinated contrast material (ICM) exposure when other contraindications to metformin use, particularly renal insufficiency neglected and leading to high plasma metformin accumulation. One of the most common questions for radiologists is when and at what level of kidney function this agent should be discontinued in cases receiving ICM and restarted again. In this study, we assess the requirement of metformin discontinuation in diabetic patients with chronic kidney disease (CKD) who are candidates for ICM. Therefore, we evaluate the step and withholding time of metformin discontinuation in CKD patients programmed for angiography with an intravenous contrast agent. Results demonstrated that for patients with uncertain renal function and individuals with normal estimated glomerular filtration rate and other diseases, the assessment to discontinue metformin (Before or at the time of the procedure) and when to reinitiate this drug should be made the decision, based on the individual’s circumstances.","PeriodicalId":16964,"journal":{"name":"Journal of Renal Endocrinology","volume":"120 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"73530942","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Diseases of the parathyroid glands in chronic kidney disease","authors":"M. Moonesan","doi":"10.34172/jre.2023.25130","DOIUrl":"https://doi.org/10.34172/jre.2023.25130","url":null,"abstract":"Chronic kidney disease (CKD) is a prevalent health condition that affects millions of people worldwide. One of the common complications of CKD is CKD-mineral and bone disorder (CKD-MBD), which involves the disturbances in mineral metabolism and skeletal health due to complications of CKD. The parathyroid glands, which is a small gland located near the thyroid glands in the neck, plays a vital role in regulating calcium and phosphorus metabolism in the body. CKD can result in the dysfunction of the parathyroid glands, leading to a range of complicated disorders.","PeriodicalId":16964,"journal":{"name":"Journal of Renal Endocrinology","volume":"11 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"74499406","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Renal effects of hydatiform mole and choriocarcinoma","authors":"H. Nasri","doi":"10.34172/jre.2023.25097","DOIUrl":"https://doi.org/10.34172/jre.2023.25097","url":null,"abstract":"Molar pregnancy is an abnormal growth of trophoblastic tissue in the uterus. It can be either complete or partial. In complete moles, the development of the fetus is absent, while partial moles contain an abnormal gestational sac. Choriocarcinoma is a malignant form that arise from molar tissue. Hydatiform mole and choriocarcinoma are rare and complicated diseases with numerous pathological conditions that can lead to significant kidney damage. Proteinuria, nephrotic syndrome, preeclampsia, decreased glomerular filtration rate, interstitial inflammation, crescentic glomerulonephritis, and thrombosis of the renal veins are the commonly encountered renal disorders with these diseases. Early intervention and treatment during pregnancy minimize these risks and lessen the risk of chronic kidney disease or end-stage renal failure. A multidisciplinary team approach involving obstetricians, nephrologists, pathologists, gynecologists, and radiologists is necessary for optimal management.","PeriodicalId":16964,"journal":{"name":"Journal of Renal Endocrinology","volume":"54 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"82779932","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}