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Journal of Pre-Clinical and Clinical Research最新文献

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Viability of human Mesenchymal stem cells from the periradicular region at different concentrations of sodium hypochlorite – systematic review 人间质干细胞在不同浓度次氯酸钠条件下的存活率--系统综述
Journal of Pre-Clinical and Clinical Research Pub Date : 2023-11-15 DOI: 10.26444/jpccr/174684
Maria Cristina Valença de Oliveira, M. Silva, Zilda Betânia Barbosa Medeiros de Farias, Pedro Henrique Sette de Souza, P. Álvares, Ana Paula Veras Sobral
{"title":"Viability of human Mesenchymal stem cells from the periradicular region at different concentrations of sodium hypochlorite – systematic review","authors":"Maria Cristina Valença de Oliveira, M. Silva, Zilda Betânia Barbosa Medeiros de Farias, Pedro Henrique Sette de Souza, P. Álvares, Ana Paula Veras Sobral","doi":"10.26444/jpccr/174684","DOIUrl":"https://doi.org/10.26444/jpccr/174684","url":null,"abstract":"Systematic","PeriodicalId":16886,"journal":{"name":"Journal of Pre-Clinical and Clinical Research","volume":"20 3","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-11-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139271024","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
RNA therapeutics: revolutionizing drug discovery RNA疗法:革命性的药物发现
Journal of Pre-Clinical and Clinical Research Pub Date : 2023-10-31 DOI: 10.4081/pcr.2023.9867
Sridhar Vemulapalli
{"title":"RNA therapeutics: revolutionizing drug discovery","authors":"Sridhar Vemulapalli","doi":"10.4081/pcr.2023.9867","DOIUrl":"https://doi.org/10.4081/pcr.2023.9867","url":null,"abstract":"Not available.","PeriodicalId":16886,"journal":{"name":"Journal of Pre-Clinical and Clinical Research","volume":"2006 9","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-10-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135813545","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Spindle cell carcinoma in the maxilla: an uncommon aggressive malignancy – case report 上颌骨梭形细胞癌:一罕见的侵袭性恶性肿瘤病例报告
Journal of Pre-Clinical and Clinical Research Pub Date : 2023-10-18 DOI: 10.26444/jpccr/174061
Lena Sobiech, Magdalena Zawadka, Aleksandra Dolina
{"title":"Spindle cell carcinoma in the maxilla: an uncommon aggressive malignancy – case report","authors":"Lena Sobiech, Magdalena Zawadka, Aleksandra Dolina","doi":"10.26444/jpccr/174061","DOIUrl":"https://doi.org/10.26444/jpccr/174061","url":null,"abstract":"1. Siegel RL, Miller KD, Fuchs HE, et al. Cancer statistics, 2021. CA Cancer J Clin. 2021;71:7–33. Google Scholar","PeriodicalId":16886,"journal":{"name":"Journal of Pre-Clinical and Clinical Research","volume":"76 4 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-10-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135884846","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Use of electrical stimulation for pain relief in a phantom limb – a systematic review 电刺激缓解幻肢疼痛的系统回顾
Journal of Pre-Clinical and Clinical Research Pub Date : 2023-10-13 DOI: 10.26444/jpccr/173005
Gabrieli Tais Haito, Isabella Floriano Cena da Silva, João Antonio Balsan Mira, Nathan Henrique Bezerra, Renata Anddresa Stachelski, Márcia Rosângela Buzanello, Gladson Ricardo Flor Bertolini
{"title":"Use of electrical stimulation for pain relief in a phantom limb – a systematic review","authors":"Gabrieli Tais Haito, Isabella Floriano Cena da Silva, João Antonio Balsan Mira, Nathan Henrique Bezerra, Renata Anddresa Stachelski, Márcia Rosângela Buzanello, Gladson Ricardo Flor Bertolini","doi":"10.26444/jpccr/173005","DOIUrl":"https://doi.org/10.26444/jpccr/173005","url":null,"abstract":"1. Souza YP de, Santos ACO dos, Albuquerque LC de. Characterization of amputees at a large hospital in Recife, PE, Brazil. J Vasc Bras 2019;18:8:e2019006. https://doi.org/10.1590/1677-5.... CrossRef Google Scholar","PeriodicalId":16886,"journal":{"name":"Journal of Pre-Clinical and Clinical Research","volume":"15 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-10-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135859085","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Negative effect of general anesthesia on the human brain - mechanism and methods of prevention 全身麻醉对人脑的负面影响——机制及预防方法
Journal of Pre-Clinical and Clinical Research Pub Date : 2023-10-06 DOI: 10.26444/jpccr/172967
Aleksandra Dembowska, Maciej Dubaj, Karol Bigosiński, Rafał Rutyna
{"title":"Negative effect of general anesthesia on the human brain - mechanism and methods of prevention","authors":"Aleksandra Dembowska, Maciej Dubaj, Karol Bigosiński, Rafał Rutyna","doi":"10.26444/jpccr/172967","DOIUrl":"https://doi.org/10.26444/jpccr/172967","url":null,"abstract":"1. Lenhardt R. Body temperature regulation and anaesthesia. Handb Clin Neurol. 2018;157:635–644. doi: 10.1016/B978–0–444–64074–1.00037–9. CrossRef Google Scholar","PeriodicalId":16886,"journal":{"name":"Journal of Pre-Clinical and Clinical Research","volume":"36 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-10-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135351379","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Vitamin D deficiency as a risk factor for developing autism in childhood – literature review 缺乏维生素 D 是儿童患自闭症的风险因素--文献综述
Journal of Pre-Clinical and Clinical Research Pub Date : 2023-09-29 DOI: 10.26444/jpccr/172126
Klaudia Szumna, Dagmara Mitas, Weronika Bartos, Kinga Mitas, Patrycja Skiba, Magdalena Niećko, Justyna Szpyra
{"title":"Vitamin D deficiency as a risk factor for developing autism in childhood – literature review","authors":"Klaudia Szumna, Dagmara Mitas, Weronika Bartos, Kinga Mitas, Patrycja Skiba, Magdalena Niećko, Justyna Szpyra","doi":"10.26444/jpccr/172126","DOIUrl":"https://doi.org/10.26444/jpccr/172126","url":null,"abstract":"Introduction and Objective. Both autism and vitamin D deficiency are increasingly prevalent among children. Vitamin D is believed to play a key role in many developmental pathways. The aim of this study is to review current knowledge of the relationship between autism spectrum disease and vitamin D deficiency among the paediatric population. Review Methods. The review was performed using the PubMed and Cochrane database from the last 10 years. The terms ‘autism’ and ‘vitamin D deficiency’ were searched for. There were 15 articles in English on the PubMed database, 14 were included in the review. In the Cochrane database they were 16 position, 9 of which were included in the final analysis. Brief description of the state of knowledge. Autism spectrum disorder (ASD) is a neurodevelopmental disorder. Typical signs are limited social relations, communication disorder and stereotyped and repetitive behaviours of varying severity. The etiology is still unknown, but nowadays the role of vitamin D deficiency isbeing investigated as a possible risk factor for ASD. There are many scientific reports of the mechanisms of action of vitamin D on the nervous system, as well as on the immune system and all cellular processes, which focus mainly on the regulation of calcium-depending systems, and antioxidant pathways. Vitamin D deficiency during pregnancy and early childhood can significantly affect the developing brain, predisposing to diseases such as autism and schizophrenia. Summary. Further research is still needed to determine the real impact of vitamin D deficiency on the risk of neurodevelopmental disorders, as well as the possibility of using supplementation as a form of treatment.","PeriodicalId":16886,"journal":{"name":"Journal of Pre-Clinical and Clinical Research","volume":"18 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-09-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139334210","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The impact of gestational diabetes on changes in the concentration of selected hormones regulating food intake in umbilical cord blood, and the development of obesity in children in later life 妊娠糖尿病对脐带血中某些调节食物摄入量的激素浓度变化的影响，以及对儿童日后肥胖症发展的影响
Journal of Pre-Clinical and Clinical Research Pub Date : 2023-09-29 DOI: 10.26444/jpccr/172938
Małgorzata Wojciechowska, Z. Chęcińska-Maciejewska, E. Pruszyńska‐Oszmałek, Andrzej Ciborek, M. Gibas-Dorna, Anna Rękas-Dudziak, Hanna Krauss, P. Kołodziejski
{"title":"The impact of gestational diabetes on changes in the concentration of selected hormones regulating food intake in umbilical cord blood, and the development of obesity in children in later life","authors":"Małgorzata Wojciechowska, Z. Chęcińska-Maciejewska, E. Pruszyńska‐Oszmałek, Andrzej Ciborek, M. Gibas-Dorna, Anna Rękas-Dudziak, Hanna Krauss, P. Kołodziejski","doi":"10.26444/jpccr/172938","DOIUrl":"https://doi.org/10.26444/jpccr/172938","url":null,"abstract":"The impact of gestational diabetes on changes in the concentration of selected hormones regulating food intake in umbilical cord blood, and the development of obesity in children in later life. J Pre-Clin","PeriodicalId":16886,"journal":{"name":"Journal of Pre-Clinical and Clinical Research","volume":"20 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-09-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139334177","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Dostarlimab as a promising immunotherapy for endometrial cancer treatment – literature review dostarlimumab作为一种有前景的子宫内膜癌免疫疗法-文献综述
Journal of Pre-Clinical and Clinical Research Pub Date : 2023-09-21 DOI: 10.26444/jpccr/172403
Kamila Derlatka, Justyna Tasior, Marika Kulczycka, Wioletta Pasieczna, Monika Prendecka-Wróbel
{"title":"Dostarlimab as a promising immunotherapy for endometrial cancer treatment – literature review","authors":"Kamila Derlatka, Justyna Tasior, Marika Kulczycka, Wioletta Pasieczna, Monika Prendecka-Wróbel","doi":"10.26444/jpccr/172403","DOIUrl":"https://doi.org/10.26444/jpccr/172403","url":null,"abstract":"1. Alexa M, Hasenburg A, Battista MJ. The TCGA Molecular Classification of Endometrial Cancer and Its Possible Impact on Adjuvant Treatment Decisions. Cancers (Basel). 2021;13(6):1478. doi:10.3390/cancers13061478. CrossRef Google Scholar","PeriodicalId":16886,"journal":{"name":"Journal of Pre-Clinical and Clinical Research","volume":"23 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-09-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"136152962","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The use of stem cells in the treatment of cerebral palsy 干细胞在脑瘫治疗中的应用
Journal of Pre-Clinical and Clinical Research Pub Date : 2023-09-20 DOI: 10.26444/jpccr/171305
Magdalena Chrościńska-Krawczyk, Aleksandra Ziółkiewicz, Aleksandra Jartych, Piotr Więsyk, Michał Bielak, Natalia Biel
{"title":"The use of stem cells in the treatment of cerebral palsy","authors":"Magdalena Chrościńska-Krawczyk, Aleksandra Ziółkiewicz, Aleksandra Jartych, Piotr Więsyk, Michał Bielak, Natalia Biel","doi":"10.26444/jpccr/171305","DOIUrl":"https://doi.org/10.26444/jpccr/171305","url":null,"abstract":"1. Vitrikas K, Dalton H, Breish D. Cerebral Palsy: An Overview. Am Fam Physician. 2020 Feb 15;101(4):213–220. PMID: 32053326. Pubmed Google Scholar","PeriodicalId":16886,"journal":{"name":"Journal of Pre-Clinical and Clinical Research","volume":"72 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-09-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"136313318","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The relationship between biological factors (vitamin D, prolactin, oxytocin, thyroid hormones) , Pregnancy-Related Anxiety and Maternal-Foetal Attachment 生物因素(维生素D、催乳素、催产素、甲状腺激素)与妊娠焦虑和母婴依恋的关系
Journal of Pre-Clinical and Clinical Research Pub Date : 2023-09-14 DOI: 10.26444/jpccr/171530
Agata Alicja Mikolajkow, Tomasz Fuchs, Krzysztof Malyszczak
{"title":"The relationship between biological factors (vitamin D, prolactin, oxytocin, thyroid hormones) , Pregnancy-Related Anxiety and Maternal-Foetal Attachment","authors":"Agata Alicja Mikolajkow, Tomasz Fuchs, Krzysztof Malyszczak","doi":"10.26444/jpccr/171530","DOIUrl":"https://doi.org/10.26444/jpccr/171530","url":null,"abstract":"1. Brunton RJ, Dryer R, Saliba A, Kohlhoff J. The initial development of the Pregnancy-related Anxiety Scale. Women and Birth. 2019;32(1):118–130. doi:10.1016/j.wombi.2018.05.004. CrossRef Google Scholar","PeriodicalId":16886,"journal":{"name":"Journal of Pre-Clinical and Clinical Research","volume":"17 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-09-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"134912661","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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