Journal of Prosthetic Dentistry最新文献

{"title":"Effect of fixed prosthetic restorations on early patient-reported outcomes following free gingival graft surgery: A prospective parallel-group clinical study","authors":"Serap Karakıs Akcan DDS, PhD, Busra Terzioglu DDS, PhD, Berceste Guler Ayyildiz DDS, PhD","doi":"10.1016/j.prosdent.2026.07.021","DOIUrl":"10.1016/j.prosdent.2026.07.021","url":null,"abstract":"<div><h3>Statement of problem</h3><div>Fixed dental prostheses create a different pericervical environment, yet studies comparing patient-reported outcome measures (PROMs) after free gingival grafting (FGG) between restored and nonrestored teeth remain limited.</div></div><div>Fixed dental prostheses create a different pericervical environment, yet studies comparing patient-reported outcome measures (PROMs) after free gingival grafting (FGG) between restored and nonrestored teeth remain limited.</div><div><h3>Purpose</h3><div>The purpose of this prospective parallel-group clinical study was to compare early postoperative PROMs, pain, and patient satisfaction after FGG in restored and nonrestored teeth.</div></div><div>The purpose of this prospective parallel-group clinical study was to compare early postoperative PROMs, pain, and patient satisfaction after FGG in restored and nonrestored teeth.</div><div><h3>Material and methods</h3><div>This study included 49 systemically healthy participants undergoing FGG at sites with keratinized tissue width (KTW) <1 mm. The participants were allocated to a restored tooth group (RTG) or a nonrestored tooth group (NTG). Clinical parameters were recorded at baseline (T0) and at 30 days (T30). Graft dimensions were recorded intraoperatively. Postoperative pain, analgesic consumption, and PROMs using the Oral Health Impact Profile (OHIP-14) were assessed at T0, T1, T7, and T30.</div></div><div>This study included 49 systemically healthy participants undergoing FGG at sites with keratinized tissue width (KTW) <1 mm. The participants were allocated to a restored tooth group (RTG) or a nonrestored tooth group (NTG). Clinical parameters were recorded at baseline (T0) and at 30 days (T30). Graft dimensions were recorded intraoperatively. Postoperative pain, analgesic consumption, and PROMs using the Oral Health Impact Profile (OHIP-14) were assessed at T0, T1, T7, and T30.</div><div><h3>Results</h3><div>Baseline OHIP-14 scores (functional limitation and behavioral impact) were significantly higher in the RTG. Generalized estimating equation analysis showed a significant time effect for total OHIP-14 scores (Wald χ²=32.943, <em>P</em><.001), with no significant group or interaction effects <strong>(</strong>group, <em>P</em>=.102; interaction, <em>P</em>=.240). Scores peaked at T1, improved by T7, and approached baseline at T30. Postoperative pain (Wald χ²=55.074, <em>P</em><.001) and analgesic consumption (Wald χ²=45.056, <em>P</em><.001) also showed significant time effects without group differences. Regression analysis identified mean analgesic consumption as the only predictor of patient satisfaction.</div></div><div>Baseline OHIP-14 scores (functional limitation and behavioral impact) were significantly higher in the RTG. Generalized estimating equation analysis showed a significant time effect for total OHIP-14 scores (Wald χ²=32.943, <em>P</em><.001), with no significant group or interaction e","PeriodicalId":16866,"journal":{"name":"Journal of Prosthetic Dentistry","volume":"136 4","pages":"Pages 1121-1132"},"PeriodicalIF":5.6,"publicationDate":"2026-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148794691","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Equivalence of linear facial measurements obtained from smartphone-based 3-dimensional facial scanners and professional extraoral scanners: A retrospective clinical study","authors":"Justine Bouscasse DDS, Virginie Chuy DDS, PhD, Louise Viel DDS, Adrien Laran DDS, Adrien Naveau DDS, PhD","doi":"10.1016/j.prosdent.2026.07.015","DOIUrl":"10.1016/j.prosdent.2026.07.015","url":null,"abstract":"<div><h3>Statement of problem</h3><div>Three-dimensional (3D) facial scanning has been increasingly integrated into digital dental workflows. Smartphone-based 3D facial scanning applications offer an accessible alternative to professional extraoral scanners; however, their metric validity for clinically relevant facial measurements remains unclear.</div></div><div>Three-dimensional (3D) facial scanning has been increasingly integrated into digital dental workflows. Smartphone-based 3D facial scanning applications offer an accessible alternative to professional extraoral scanners; however, their metric validity for clinically relevant facial measurements remains unclear.</div><div><h3>Purpose</h3><div>The purpose of this retrospective clinical study was to determine whether linear facial measurements obtained from smartphone-based 3D facial scanning applications were statistically equivalent to those obtained from professional extraoral facial scanners.</div></div><div>The purpose of this retrospective clinical study was to determine whether linear facial measurements obtained from smartphone-based 3D facial scanning applications were statistically equivalent to those obtained from professional extraoral facial scanners.</div><div><h3>Material and methods</h3><div>Facial scans from 23 participants, obtained via repeated scanning with smartphone-based scanners (Qlone, Magiscan, 3D App Scanner, on iPhone 13 Pro; Apple Inc) and professional scanners (Artec Spider; Artec, EinStar; Shining 3D), were retrospectively analyzed. Four facial distances (trichion–nasion, nasion–pronasion, pronasion–pogonion, and right zygomatic–left zygomatic) were measured on all scans. The equivalence of these distances between smartphone-based scanners and each professional scanner was assessed using the two 1-sided <em>t</em> tests (TOST) procedure with a predefined equivalence margin of ±1 mm and Bonferroni-adjusted significance levels.</div></div><div>Facial scans from 23 participants, obtained via repeated scanning with smartphone-based scanners (Qlone, Magiscan, 3D App Scanner, on iPhone 13 Pro; Apple Inc) and professional scanners (Artec Spider; Artec, EinStar; Shining 3D), were retrospectively analyzed. Four facial distances (trichion–nasion, nasion–pronasion, pronasion–pogonion, and right zygomatic–left zygomatic) were measured on all scans. The equivalence of these distances between smartphone-based scanners and each professional scanner was assessed using the two 1-sided <em>t</em> tests (TOST) procedure with a predefined equivalence margin of ±1 mm and Bonferroni-adjusted significance levels.</div><div><h3>Results</h3><div>Across all distances, smartphone-based and professional scanners were statistically equivalent, with absolute mean differences below 0.12 mm (90% confidence interval: −0.03 to 0.26; <em>P</em><.001 for all comparisons).</div></div><div>Across all distances, smartphone-based and professional scanners were statistically equivalent, with absol","PeriodicalId":16866,"journal":{"name":"Journal of Prosthetic Dentistry","volume":"136 4","pages":"Pages 1200-1206"},"PeriodicalIF":5.6,"publicationDate":"2026-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148697558","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A digitally guided workflow integrating tooth preparation and restoration positioning for minimally invasive veneer and partial-coverage restorations: A dental technique","authors":"Patricia Elias-Ortiz DDS, MSc,&nbsp;Carlos Eduardo Toro-Chacón DDS, MSc,&nbsp;Nicolás Veneri-Rodríguez DDS, MSc,&nbsp;Nelson Gerardo Rodríguez Briceño DDS,&nbsp;Juan Ruiz-de-Gopegui DDS, MSc,&nbsp;Solange Vásquez-Ramos DDS, MSc,&nbsp;Miguel Gómez-Polo DDS, PhD","doi":"10.1016/j.prosdent.2026.06.037","DOIUrl":"10.1016/j.prosdent.2026.06.037","url":null,"abstract":"<div><div>Minimally invasive veneer restorations require control of tooth preparation, restoration design, and the final placement to accomplish predictable esthetics. Digital workflows have been proposed to improve the accuracy of veneer preparations; however, many approaches focus primarily on controlling tooth reduction. This dental technique aims to describe a fully digital workflow for V-veneers, minimally invasive restorations involving the facial surface with limited occlusal extension, and V-onlays, partial coverage restorations involving both vestibular and occlusal surface. The treatment is aided digitally with the production of preparation guides and positioning splints.</div></div><div>Minimally invasive veneer restorations require control of tooth preparation, restoration design, and the final placement to accomplish predictable esthetics. Digital workflows have been proposed to improve the accuracy of veneer preparations; however, many approaches focus primarily on controlling tooth reduction. This dental technique aims to describe a fully digital workflow for V-veneers, minimally invasive restorations involving the facial surface with limited occlusal extension, and V-onlays, partial coverage restorations involving both vestibular and occlusal surface. The treatment is aided digitally with the production of preparation guides and positioning splints.</div>","PeriodicalId":16866,"journal":{"name":"Journal of Prosthetic Dentistry","volume":"136 4","pages":"Pages 911-916"},"PeriodicalIF":5.6,"publicationDate":"2026-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148794648","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Implant-supported overdenture placement after fibula flap–based mandibular reconstruction using guided bone regeneration with titanium mesh and tenting screws: A clinical report","authors":"Kensuke Yamauchi DDS, PhD,&nbsp;Kazuhiro Imoto DDS, PhD,&nbsp;Naoko Sato DDS, PhD,&nbsp;Shigeto Koyama DDS, PhD","doi":"10.1016/j.prosdent.2026.06.040","DOIUrl":"10.1016/j.prosdent.2026.06.040","url":null,"abstract":"<div><div>A 63-year-old man underwent segmental mandibulectomy for ameloblastoma, followed by fibula free-flap reconstruction. As the bone volume was inadequate, guided bone regeneration (GBR) was performed using iliac particulate cancellous bone and marrow, titanium mesh, and tenting screws. After consolidation, 4 implants were placed, and restoration was completed with a computer-aided design and computer-aided manufacturing titanium bar and LOCATOR-retained overdenture. This staged approach ensured stable implant placement and successful rehabilitation. At 1 year postoperatively, the patient’s appearance and masticatory function had improved significantly, with no peri-implant or prosthetic complication. The combined application of GBR and a 2-stage protocol after fibula flap surgery enables the predictable achievement of functional reconstruction.</div></div><div>A 63-year-old man underwent segmental mandibulectomy for ameloblastoma, followed by fibula free-flap reconstruction. As the bone volume was inadequate, guided bone regeneration (GBR) was performed using iliac particulate cancellous bone and marrow, titanium mesh, and tenting screws. After consolidation, 4 implants were placed, and restoration was completed with a computer-aided design and computer-aided manufacturing titanium bar and LOCATOR-retained overdenture. This staged approach ensured stable implant placement and successful rehabilitation. At 1 year postoperatively, the patient’s appearance and masticatory function had improved significantly, with no peri-implant or prosthetic complication. The combined application of GBR and a 2-stage protocol after fibula flap surgery enables the predictable achievement of functional reconstruction.</div>","PeriodicalId":16866,"journal":{"name":"Journal of Prosthetic Dentistry","volume":"136 4","pages":"Pages 1232-1236"},"PeriodicalIF":5.6,"publicationDate":"2026-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148794664","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Comment on “Restoration of endodontically treated teeth: A cost-effectiveness analysis of a one-piece endodontic crown versus a complete crown”","authors":"Miduturu Sukumar,&nbsp;Kabilan Annadurai","doi":"10.1016/j.prosdent.2026.04.042","DOIUrl":"10.1016/j.prosdent.2026.04.042","url":null,"abstract":"","PeriodicalId":16866,"journal":{"name":"Journal of Prosthetic Dentistry","volume":"136 4","pages":"Pages e139-e140"},"PeriodicalIF":5.6,"publicationDate":"2026-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148579020","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Response to the Letter to the Editor, “Comment on 'Readability and performance of AI chatbot responses to frequently asked questions in maxillofacial prosthodontics'”","authors":"Soni Prasad BDS, MS, MBA,&nbsp;Merve Koseoglu DDS,&nbsp;Stavroula Antonopoulou DDS, MS,&nbsp;Leila M. Sears DMD, MDS,&nbsp;Vinsensia Launardo DDS, MS,&nbsp;Nina Ariani DDS, PhD,&nbsp;Nadine Ziad Mirza DDS, MDSc,&nbsp;Amanda Colebeck DDS, MS,&nbsp;Banu Karayazgan DDS, PhD,&nbsp;Maribeth Krzesinski DDS,&nbsp;Alvin G. Wee DDS, BDS, MS, MPH, PhD,&nbsp;Cortino Sukotjo DDS, PhD, MMSc, MHPE","doi":"10.1016/j.prosdent.2026.06.019","DOIUrl":"10.1016/j.prosdent.2026.06.019","url":null,"abstract":"","PeriodicalId":16866,"journal":{"name":"Journal of Prosthetic Dentistry","volume":"136 4","pages":"Pages e145-e146"},"PeriodicalIF":5.6,"publicationDate":"2026-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148405340","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effect of ultrasonic chemical cleaning solutions on different dental interim restoration material properties. Part I: Physical properties of color stability and surface roughness","authors":"Kawther Ali BDM, B.Med.SC, MS,&nbsp;Ahmad Alenezi BSc, MSc, PhD,&nbsp;Abdulaziz A. Alzaid BDS, MS,&nbsp;Charles Goodacre DDS, MSD","doi":"10.1016/j.prosdent.2026.07.024","DOIUrl":"10.1016/j.prosdent.2026.07.024","url":null,"abstract":"&lt;div&gt;&lt;h3&gt;Statement of problem&lt;/h3&gt;&lt;div&gt;Cleaning dental interim crowns between treatment visits using chemical agents may affect color stability and surface roughness. Studies investigating the reaction of different interim materials with different cleaning solutions are lacking.&lt;/div&gt;&lt;/div&gt;&lt;div&gt;Cleaning dental interim crowns between treatment visits using chemical agents may affect color stability and surface roughness. Studies investigating the reaction of different interim materials with different cleaning solutions are lacking.&lt;/div&gt;&lt;div&gt;&lt;h3&gt;Purpose&lt;/h3&gt;&lt;div&gt;The purpose of this in vitro study was to evaluate the effect of ultrasonic chemical cleaning solutions on the color stability and surface roughness of conventionally and computer-aided design and computer-aided manufacturing (CAD-CAM) fabricated dental interim materials.&lt;/div&gt;&lt;/div&gt;&lt;div&gt;The purpose of this in vitro study was to evaluate the effect of ultrasonic chemical cleaning solutions on the color stability and surface roughness of conventionally and computer-aided design and computer-aided manufacturing (CAD-CAM) fabricated dental interim materials.&lt;/div&gt;&lt;div&gt;&lt;h3&gt;Material and methods&lt;/h3&gt;&lt;div&gt;A total of 192 interim restoration specimens were fabricated using the following materials and fabrication methods: conventional chemically activated polymethyl methacrylate (PMMA) &lt;em&gt;n&lt;/em&gt;=48, bis-acrylic composite &lt;em&gt;n&lt;/em&gt;=48, milled PMMA &lt;em&gt;n&lt;/em&gt;=48, and 3-dimensional (3D) printed resin &lt;em&gt;n&lt;/em&gt;=48. Each group was treated with 4 solutions (water &lt;em&gt;n&lt;/em&gt;=12, general purpose cleaner &lt;em&gt;n&lt;/em&gt;=12, calculus and stain cleaner &lt;em&gt;n&lt;/em&gt;=12, and cement remover cleaner &lt;em&gt;n&lt;/em&gt;=12). Each specimen was immersed in the assigned solution for 5 cycles of 10 minutes using an ultrasonic water bath. Color measurements and surface roughness were obtained for each specimen at baseline, after 2 cycles, and after 5 cycles using a spectrophotometer and optical profiler, respectively. A repeated measures linear mixed model analysis was performed to detect differences in color changes and surface roughness between different interim materials and different solutions after 2 and 5 cycles of ultrasonic cleaning (α=.05).&lt;/div&gt;&lt;/div&gt;&lt;div&gt;A total of 192 interim restoration specimens were fabricated using the following materials and fabrication methods: conventional chemically activated polymethyl methacrylate (PMMA) &lt;em&gt;n&lt;/em&gt;=48, bis-acrylic composite &lt;em&gt;n&lt;/em&gt;=48, milled PMMA &lt;em&gt;n&lt;/em&gt;=48, and 3-dimensional (3D) printed resin &lt;em&gt;n&lt;/em&gt;=48. Each group was treated with 4 solutions (water &lt;em&gt;n&lt;/em&gt;=12, general purpose cleaner &lt;em&gt;n&lt;/em&gt;=12, calculus and stain cleaner &lt;em&gt;n&lt;/em&gt;=12, and cement remover cleaner &lt;em&gt;n&lt;/em&gt;=12). Each specimen was immersed in the assigned solution for 5 cycles of 10 minutes using an ultrasonic water bath. Color measurements and surface roughness were obtained for each specimen at baseline, after 2 cycles, and after 5 cycles using a spectrophotometer and optical profiler, resp","PeriodicalId":16866,"journal":{"name":"Journal of Prosthetic Dentistry","volume":"136 4","pages":"Pages 1214-1222"},"PeriodicalIF":5.6,"publicationDate":"2026-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148794702","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Letter to the Editor regarding, “Dimensional accuracy and clinical adaptation of monolithic zirconia crowns fabricated with the nanoparticle jetting technique” and “Effect of finish line designs on the dimensional accuracy of monolithic zirconia crowns fabricated with a material jetting technique” by Lyu et al","authors":"Sherif Sultan BDS, MSc, PhD","doi":"10.1016/j.prosdent.2026.05.056","DOIUrl":"10.1016/j.prosdent.2026.05.056","url":null,"abstract":"","PeriodicalId":16866,"journal":{"name":"Journal of Prosthetic Dentistry","volume":"136 4","pages":"Page e136"},"PeriodicalIF":5.6,"publicationDate":"2026-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148396975","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Complete mouth rehabilitation with implant-supported fixed prosthesis in a patient with pemphigus vulgaris: A clinical report","authors":"Muhammad Ahsan Kaleem Khan BDS,&nbsp;Syed Murtaza Raza Kazmi BDS, FCPS, MHPE, FICOI, FHEA, FDTFed,&nbsp;Taimur Khalid BDS, MDSc, MCLINDENT, M PROS RCSEd","doi":"10.1016/j.prosdent.2026.06.039","DOIUrl":"10.1016/j.prosdent.2026.06.039","url":null,"abstract":"<div><div>This clinical report describes the prosthetic rehabilitation of a 59-year-old edentulous woman with pemphigus vulgaris using implant-supported fixed prostheses. The treatment involved the placement of endosseous dental implants with cone beam computed tomography guided planning, followed by multiunit abutments and screw-retained prostheses. At the 3-year follow-up, the patient had experienced significant improvement in health, esthetics, and function, with stable implants and minimal bone loss.</div></div><div>This clinical report describes the prosthetic rehabilitation of a 59-year-old edentulous woman with pemphigus vulgaris using implant-supported fixed prostheses. The treatment involved the placement of endosseous dental implants with cone beam computed tomography guided planning, followed by multiunit abutments and screw-retained prostheses. At the 3-year follow-up, the patient had experienced significant improvement in health, esthetics, and function, with stable implants and minimal bone loss.</div>","PeriodicalId":16866,"journal":{"name":"Journal of Prosthetic Dentistry","volume":"136 4","pages":"Pages 897-901"},"PeriodicalIF":5.6,"publicationDate":"2026-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148712670","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Salivary flow and oral health-related quality of life in edentulous denture stomatitis positive individuals: A randomized clinical trial","authors":"Adriana Barbosa Ribeiro DDS, PhD,&nbsp;Lorena Mosconi Clemente DDS, MSc,&nbsp;Beatriz de Camargo Poker DDS, MSc,&nbsp;Júlio Cesar Taffarel DDS,&nbsp;Vinícius Sabedra DDS,&nbsp;Ana Paula Macedo PhD,&nbsp;Helio Cesar Salgado PhD,&nbsp;Cláudia Helena Silva-Lovato DDS, PhD","doi":"10.1016/j.prosdent.2026.07.031","DOIUrl":"10.1016/j.prosdent.2026.07.031","url":null,"abstract":"&lt;div&gt;&lt;h3&gt;Statement of problem&lt;/h3&gt;&lt;div&gt;The effects of different denture stomatitis (DS) management strategies on oral health-related quality of life (OHRQoL) and salivary flow (SF) in complete denture wearers remain unclear.&lt;/div&gt;&lt;/div&gt;&lt;div&gt;The effects of different denture stomatitis (DS) management strategies on oral health-related quality of life (OHRQoL) and salivary flow (SF) in complete denture wearers remain unclear.&lt;/div&gt;&lt;div&gt;&lt;h3&gt;Purpose&lt;/h3&gt;&lt;div&gt;The purpose of this double-blind, parallel-group randomized clinical trial was to compare the effects of nystatin therapy and sodium hypochlorite denture hygiene on OHRQoL, salivary flow (SF), and DS severity in complete denture wearers.&lt;/div&gt;&lt;/div&gt;&lt;div&gt;The purpose of this double-blind, parallel-group randomized clinical trial was to compare the effects of nystatin therapy and sodium hypochlorite denture hygiene on OHRQoL, salivary flow (SF), and DS severity in complete denture wearers.&lt;/div&gt;&lt;div&gt;&lt;h3&gt;Material and methods&lt;/h3&gt;&lt;div&gt;A total of 50 complete denture wearers with DS were allocated to 2 groups: nystatin mouth rinse (GN) or a sodium hypochlorite (GSH0.25%)-based denture hygiene protocol. OHRQoL, SF, and DS severity were assessed at baseline and at 15 and 45 days, and data were analyzed using generalized estimating equations (α=.05).&lt;/div&gt;&lt;/div&gt;&lt;div&gt;A total of 50 complete denture wearers with DS were allocated to 2 groups: nystatin mouth rinse (GN) or a sodium hypochlorite (GSH0.25%)-based denture hygiene protocol. OHRQoL, SF, and DS severity were assessed at baseline and at 15 and 45 days, and data were analyzed using generalized estimating equations (α=.05).&lt;/div&gt;&lt;div&gt;&lt;h3&gt;Results&lt;/h3&gt;&lt;div&gt;Forty-seven participants completed the study. Significant improvements over time were observed in OHRQoL overall and domains related to masticatory function, social disability, and psychological discomfort (&lt;em&gt;P&lt;/em&gt;≤.001), regardless of treatment, with no treatment-by-time interactions. SF remained stable over time, with no significant effects of treatment, time, or interaction (&lt;em&gt;P&lt;/em&gt;&gt;.05). DS severity decreased significantly over time (&lt;em&gt;P&lt;/em&gt;&lt;.001), with no significant differences between groups or interaction effects (&lt;em&gt;P&lt;/em&gt;&gt;.05).&lt;/div&gt;&lt;/div&gt;&lt;div&gt;Forty-seven participants completed the study. Significant improvements over time were observed in OHRQoL overall and domains related to masticatory function, social disability, and psychological discomfort (&lt;em&gt;P&lt;/em&gt;≤.001), regardless of treatment, with no treatment-by-time interactions. SF remained stable over time, with no significant effects of treatment, time, or interaction (&lt;em&gt;P&lt;/em&gt;&gt;.05). DS severity decreased significantly over time (&lt;em&gt;P&lt;/em&gt;&lt;.001), with no significant differences between groups or interaction effects (&lt;em&gt;P&lt;/em&gt;&gt;.05).&lt;/div&gt;&lt;div&gt;&lt;h3&gt;Conclusions&lt;/h3&gt;&lt;div&gt;Both therapies were associated with improved OHRQoL in complete denture wearers with DS. These improvements occurred alongside reductions in denture","PeriodicalId":16866,"journal":{"name":"Journal of Prosthetic Dentistry","volume":"136 4","pages":"Pages 1133-1140"},"PeriodicalIF":5.6,"publicationDate":"2026-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148794813","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}