Journal of Prosthetic Dentistry最新文献

{"title":"Gingival margin repositioning using biologically oriented preparation technique and digital workflow in a maxillary esthetic rehabilitation: A clinical report.","authors":"Eun-Hyuk Lee","doi":"10.1016/j.prosdent.2025.08.024","DOIUrl":"https://doi.org/10.1016/j.prosdent.2025.08.024","url":null,"abstract":"<p><p>This clinical report describes the management of gingival recession and gingival line asymmetry around fixed partial dentures using the biologically oriented preparation technique (BOPT). By modifying the emergence profile of the restorations through the BOPT and incorporating a digital workflow, a stable and esthetic gingival margin was achieved. The report highlights the procedural steps, advantages, and limitations of this approach in the anterior maxillary region.</p>","PeriodicalId":16866,"journal":{"name":"Journal of Prosthetic Dentistry","volume":" ","pages":""},"PeriodicalIF":4.8,"publicationDate":"2025-09-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145033598","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Enhancing bonding and durability of polyaryletherketone (PAEK) restorations with nonthermal plasma activation and monomer-based priming.","authors":"Szu-Yu Lai, Chenxuan Wei, Tzu-Yu Peng","doi":"10.1016/j.prosdent.2025.08.029","DOIUrl":"https://doi.org/10.1016/j.prosdent.2025.08.029","url":null,"abstract":"<p><strong>Statement of problem: </strong>While valued for their durability in dental prosthetics, polyaryletherketone (PAEK) materials, known for their chemical inertness and low surface energy, pose significant challenges in achieving durable adhesion to resin cements, a critical factor for the long-term success of dental restorations.</p><p><strong>Purpose: </strong>This study evaluates the novel application of a methyl methacrylate-urethane dimethacrylate (MMA-UDMA) bonding primer following handheld nonthermal plasma (HNP) treatment to enhance the bonding performance and aging durability of PAEK materials with varying microfiller compositions, addressing the persistent challenge of achieving long-term adhesion in dental restorations.</p><p><strong>Material and methods: </strong>Three PAEK types, ceramic-filled polyetheretherketone (PEEK), titanium dioxide-filled polyetherketoneketone (PEKK), and PEEK with disk shape (Ø10×2.5-mm) were airborne-particle abraded using 110-µm Al₂O₃ at 0.2 MPa. Specimens were then evenly allocated into 2 main groups: one group received surface bonding primer (SBP) application alone, while the other group underwent HNP treatment followed by primer application (PLP). Surface wettability and shear bond strength (SBS) were assessed before and after artificial aging protocols, which included thermocycling and highly accelerated stress testing. Failure modes were analyzed microscopically to identify adhesive, mixed, or cohesive failures. Statistical analysis was performed using 3-way ANOVA and the Tukey HSD test (α=.05).</p><p><strong>Results: </strong>PLP-treated groups showed significantly improved wettability and increased SBS across all materials compared with SBP (P<.05), with the PLP-treated PEKK achieving the highest SBS at 16.35 MPa. After artificial aging, PLP-treated specimens revealed minimal reduction in SBS, with PEKK maintaining superior performance and the smallest decrease observed compared with others (P<.05). Failure mode analysis indicated a higher incidence of mixed failures for PLP-treated specimens, suggesting enhanced bond durability. Statistical analysis confirmed that differences across material types and treatments were significant (P<.05), highlighting the effectiveness of the HNP and primer application in improving long-term adhesion.</p><p><strong>Conclusions: </strong>HNP treatment followed by MMA-UDMA primer application significantly improved the bonding performance and durability of PAEK materials used in dental prostheses. The current findings indicated that this method addressed the persistent challenge of achieving long-term adhesion, particularly in materials with high ketone content.</p>","PeriodicalId":16866,"journal":{"name":"Journal of Prosthetic Dentistry","volume":" ","pages":""},"PeriodicalIF":4.8,"publicationDate":"2025-09-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145033605","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Biomechanical impact of sagittal curvature radius in glenoid fossa on TMJ prosthesis performance: A finite element study of custom designs.","authors":"Manuel Mejía Rodríguez, Jhon Jairo Osorio Orozco, Kevin Díaz-Rojas, Hernán D Sánchez-Restrepo, Octavio Andrés González-Estrada","doi":"10.1016/j.prosdent.2025.08.039","DOIUrl":"https://doi.org/10.1016/j.prosdent.2025.08.039","url":null,"abstract":"<p><strong>Statement of problem: </strong>Although custom temporomandibular joint (TMJ) prostheses manufactured via computer-aided design and manufacturing (CAD-CAM) and produced through 3-dimensional (3D) printing or computer numerical control (CNC) allow for sagittal curvature adjustments in the glenoid fossa, their design remains unregulated by the Food and Drug Administration. Consequently, the geometry is determined largely by the engineer's discretion, with limited biomechanical evidence to guide these decisions. The lack of validation regarding how sagittal curvature influences joint stress distribution under various anatomical and functional conditions represents a gap in current knowledge that warrants investigation.</p><p><strong>Purpose: </strong>The purpose of this finite element method (FEM) study was to evaluate how variations in the sagittal radius of curvature of the glenoid fossa affect stress distribution in custom TMJ prostheses for 2 patients.</p><p><strong>Material and methods: </strong>A 3D reconstruction of the temporomandibular joint of 2 patients was carried out. Temporomandibular prostheses were designed with different sagittal radii of curvature at the level of the rotary hinge depending on the occlusal plane, the customized orientation of the muscles, the angle of the occlusal plane and Frankfort plane, and the direction of the load at the level of the second left molar, using FEM. Subsequently, mechanical stresses and kinematic translation were evaluated based on boundary conditions, joint constraints, bone mechanical properties, and soft tissue properties.</p><p><strong>Results: </strong>The semicircular base curvature radius #1 restricted the sagittal displacements of the prosthetic condylar head and increased the stress state on the articular surface. In contrast, the curvature radii #3 and #4 reduced the von Mises stresses and minimum principal stresses by 50% and optimized the translation of the prosthetic condylar component by 45%, respectively.</p><p><strong>Conclusions: </strong>The findings suggest that incorporating elliptical sagittal curvature radii in the design of TMJ prostheses may offer biomechanical advantages over traditional spherical models. These geometries appear to facilitate more natural joint kinematics and reduce stress, supporting their use in personalized prosthetic development to enhance joint function, longevity, and patient outcomes.</p>","PeriodicalId":16866,"journal":{"name":"Journal of Prosthetic Dentistry","volume":" ","pages":""},"PeriodicalIF":4.8,"publicationDate":"2025-09-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145033536","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A practical approach to determining screw preload in dental implant systems.","authors":"Daniel P Hess, Chandur Pk Wadhwani, Kwok Hung Chung, Alvin G Wee","doi":"10.1016/j.prosdent.2025.08.022","DOIUrl":"https://doi.org/10.1016/j.prosdent.2025.08.022","url":null,"abstract":"<p><p>A practical and novel technique used both in testing and in practice when tightening dental implant screw systems is described for determining the preload implant screw systems, which differs from traditional tightening procedures that are based solely on the application of a predetermined manufacturer specified torque value. Preload is the critical quantity for a reliable joint: about 90% of tightening torque goes into overcoming friction and the remaining amount, approximately 10%, goes into preload. Because of the heavy dependence of torque on friction, the actual preload achieved is subject to large variability of up ±35%, depending on surface conditions (dry, wet, or contaminated). Current methods of testing for preload require complex equipment such as load cells, strain gauges, or finite element analysis. This practical technique integrates tightening torque with removal torque value measurements and screw geometry to determine preload. This information subtracts out the friction components, thereby accounting for differences in surface conditions and reducing the need for multiple test conditions.</p>","PeriodicalId":16866,"journal":{"name":"Journal of Prosthetic Dentistry","volume":" ","pages":""},"PeriodicalIF":4.8,"publicationDate":"2025-09-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145033554","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Material effects on the long-term survival and complication rate of cemented implant-supported single crowns: A retrospective clinical study.","authors":"Jana Kostunov, Peter Rammelsberg","doi":"10.1016/j.prosdent.2025.08.030","DOIUrl":"https://doi.org/10.1016/j.prosdent.2025.08.030","url":null,"abstract":"<p><strong>Statement of problem: </strong>Despite high survival rates of implant-supported single crowns, retention loss remains common and decementation of crowns can compromise long-term stability, patient satisfaction, and treatment costs. Limited long-term evidence on cement type, abutment design, and materials requires further research to optimize clinical outcomes.</p><p><strong>Purpose: </strong>The aim of this retrospective clinical study was to analyze the survival and decementation rates of zirconia and metal-ceramic implant-supported crowns in combination with different abutments (prefabricated or custom and unabraded or airborne-particle abraded).</p><p><strong>Material and methods: </strong>A total of 639 implant-supported single crowns placed in 395 patients (mean age: 67.2 years; 195 men) were evaluated for up to 18 years. The frameworks were made from Au alloys (n=153) or zirconia (n=486) and were cemented with glass-ionomer cement (GIC) (n=568) or eugenol-free interim cement (n=71). A total of 416 crowns were cemented on prefabricated abutments and 223 on custom abutments. Of the abutments, 445 were unabraded, while 194 were airborne-particle abraded before cementation. The variables crown framework, abutment type, abutments surface treatment, and cement type were analyzed using Kaplan-Meier analysis, log-rank tests, and Cox regression analysis (α=.05).</p><p><strong>Results: </strong>A total of 18 crowns failed and required replacement because of veneer chipping (n=9), abutment loosening (n=3), or implant loss (n=6). In addition to the failures, 38 crown decementations were documented. The decementation rate for airborne-particle abraded abutments after 18 years was 10% while unabraded abutments showed a 5% risk of decementation (P=.252). Prefabricated abutments showed a higher decementation rate of 8% after 10 years compared to custom abutments (2%, P=.031). For zirconia single crowns, the decementation rate was significantly lower at 4% compared to Au frameworks at 14% (P=.011). The type of cement had a significant influence: interim cement led to a decementation rate of 25%, while glass-ionomer cement only led to a loss of retention in 3.5% of the crowns (P<.001).</p><p><strong>Conclusions: </strong>Zirconia crowns can be successfully used with glass-ionomer cement in the long term. Interim cements cannot be recommended because of the high decementation rate.</p>","PeriodicalId":16866,"journal":{"name":"Journal of Prosthetic Dentistry","volume":" ","pages":""},"PeriodicalIF":4.8,"publicationDate":"2025-09-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145033610","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Assessing the reproducibility of facebow transfers: A mesh-based intra-observer study.","authors":"Lucas Ferreira, Ana Ribeiro, Pierre-Hadrien Decaup","doi":"10.1016/j.prosdent.2025.08.038","DOIUrl":"https://doi.org/10.1016/j.prosdent.2025.08.038","url":null,"abstract":"<p><strong>Statement of problem: </strong>The reproducibility of positioning the maxillary occlusal plane in an articulator with a facebow remains debated. Its clinical use is widespread, yet its reliability and clinical outcomes compared to other transfer methods under standardized conditions remain uncertain.</p><p><strong>Purpose: </strong>The purpose of this in vitro study was to compare the intra-operator reproducibility of maxillary positioning on an articulator using a facebow compared to a standardized transfer table.</p><p><strong>Material and methods: </strong>Sixty identical maxillary replicas from a single patient were mounted by a single operator (30 using a facebow and 30 using a 10-degree inclined transfer table). Each articulator was scanned, and frontal and sagittal occlusal plane angulations were measured using a validated mesh-based method. Statistical analyses included Shapiro-Wilk test to assess normality, Fligner-Killeen and Wilcoxon rank-sum tests to compare the groups, and Cliff δ to estimate effect size.</p><p><strong>Results: </strong>The mesh-based analysis was validated with perfect intra-observer agreement. The reproducibility significantly differed for both frontal and sagittal inclinations between the facebow record and the standardized method (P<.05). Angular values also differed significantly between groups (P<.05), with a large effect size in sagittal directions (Cliff δ=1.00) and a small effect size in frontal directions (Cliff δ=0.32).</p><p><strong>Conclusions: </strong>The facebow transfer technique exhibited low reproducibility. The mesh-based protocol offered a reproducibility baseline for assessing emerging maxillary transfer techniques with a reliable measurement method.</p>","PeriodicalId":16866,"journal":{"name":"Journal of Prosthetic Dentistry","volume":" ","pages":""},"PeriodicalIF":4.8,"publicationDate":"2025-09-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145030117","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Evaluation of information provided by artificial intelligence chatbots on extraoral maxillofacial prostheses.","authors":"Nuran Özyemişci, Bilge Turhan Bal, Merve Bankoğlu Güngör, Esra Kaynak Öztürk, Ayşegül Canvar, Secil Karakoca Nemli","doi":"10.1016/j.prosdent.2025.08.028","DOIUrl":"https://doi.org/10.1016/j.prosdent.2025.08.028","url":null,"abstract":"<p><strong>Statement of problem: </strong>Despite advances in artificial intelligence (AI), the quality, reliability, and understandability of health-related information provided by chatbots is still a question mark. Furthermore, studies on maxillofacial prosthesis (MP) information from AI chatbots are lacking.</p><p><strong>Purpose: </strong>The purpose of this study was to assess and compare the reliability, quality, readability, and similarity of responses to MP-related questions generated by 4 different chatbots.</p><p><strong>Material and methods: </strong>A total of 15 questions were provided by a maxillofacial prosthodontist and from 4 different chatbots (ChatGPT-3.5, Gemini 2.5 Flash, Copilot, and DeepSeek V3). The Reliability Scoring (adapted DISCERN), the Global Quality Scale (GQS), the Flesch Reading Ease Score (FRES), the Flesch-Kincaid Reading Grade Level (FKRGL), and the Similarity Index (iThenticate) were used to evaluate the performance of chatbots. Data were compared using the Kruskal-Wallis test, and the differences between chatbots were determined by the Conover multiple comparison test with Benjamini-Hochberg correction (α=.05).</p><p><strong>Results: </strong>There were no significant differences between the chatbots' DISCERN scores, except for one question where ChatGPT showed significantly higher reliability than Gemini or Copilot (P=.03). There was no statistically significant difference among AI tools in terms of GQS values (P=.096), FRES values (P=.166), and FKRGL values (P=.247). The similarity rate of Gemini was statistically higher than other AI chatbots (P=.03).</p><p><strong>Conclusions: </strong>ChatGPT-3.5, Gemini 2.5 Flash, Copilot, and DeepSeek V3 showed good quality responses. All chatbots' responses were difficult for non-professionals to read and understand. Low similarity rates were found for all chatbots except Gemini, indicating originality of their information.</p>","PeriodicalId":16866,"journal":{"name":"Journal of Prosthetic Dentistry","volume":" ","pages":""},"PeriodicalIF":4.8,"publicationDate":"2025-09-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145030160","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A simplified digital workflow for reestablishing the vertical dimension of occlusion in a complete arch implant-supported prosthesis: A clinical report.","authors":"Fernanda Gurgel de Gois Moreira, Nathalia Ramos da Silva, Larissa Mendonça de Miranda, Eduardo Miyashita, Rodrigo Othávio de Assunção E Souza","doi":"10.1016/j.prosdent.2025.07.029","DOIUrl":"https://doi.org/10.1016/j.prosdent.2025.07.029","url":null,"abstract":"<p><p>A simplified digital workflow is described for a complete arch implant-supported prosthesis with the restoration of the vertical dimension of occlusion (VDO) using a 3-dimensionally printed interim prosthesis and an esthetic jaw incisor guide. After VDO definition and intraoral scanning, a screw-retained interim prosthesis was printed, clinically tested, and used to guide the fabrication of the definitive prosthesis. The approach showed predictable esthetic and functional results, though caution is needed in patients with parafunctional habits because of the limited strength of printed resins.</p>","PeriodicalId":16866,"journal":{"name":"Journal of Prosthetic Dentistry","volume":" ","pages":""},"PeriodicalIF":4.8,"publicationDate":"2025-09-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145008322","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Plastic surgery-maxillofacial prosthetics collaboration for facial prostheses for a patient with changes in facial morphology: A clinical report.","authors":"Shigeto Koyama, Takayuki Harata, Naoko Sato, Nobuhiro Yoda","doi":"10.1016/j.prosdent.2025.08.006","DOIUrl":"https://doi.org/10.1016/j.prosdent.2025.08.006","url":null,"abstract":"<p><p>A 63-year-old man underwent extensive maxillectomy, followed by reconstruction using a rectus abdominis musculocutaneous free flap. Subsequently, he received guided flap-correction surgery to insert a facial prosthesis. Over time, the initial prosthesis became inadequate because of morphological changes and color mismatch caused by seasonal variations in skin tone. Three-dimensional (3D) digital technologies enabled the reassessment of his facial profile and allowed the fabrication of a replacement prosthesis that accommodated these changes. This report highlights the importance of the application of 3D digital technology for the fabrication of facial prostheses and of multidisciplinary collaboration for successful maxillofacial prosthodontic treatment.</p>","PeriodicalId":16866,"journal":{"name":"Journal of Prosthetic Dentistry","volume":" ","pages":""},"PeriodicalIF":4.8,"publicationDate":"2025-09-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145000794","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Three-year clinical and radiographic outcomes of splinted versus nonsplinted extrashort implants in atrophic mandibles: A split-mouth randomized clinical trial.","authors":"Aloizio Filgueiras, Dione Gonçalves Pinto, Leandro Marques de Resende, Bruno Salles Sotto-Maior","doi":"10.1016/j.prosdent.2025.08.013","DOIUrl":"https://doi.org/10.1016/j.prosdent.2025.08.013","url":null,"abstract":"<p><strong>Statement of problem: </strong>Whether the unfavorable crown-to-implant ratio of extrashort implants and the use of splinted versus nonsplinted crowns affects marginal bone loss and implant survival remains unclear.</p><p><strong>Purpose: </strong>The purpose of this split-mouth randomized clinical trial was to evaluate the effect of splinting on survival rates and clinical and radiographic parameters associated with prostheses supported by extrashort implants in the posterior region of atrophic mandibles over a 3-year follow-up period.</p><p><strong>Material and methods: </strong>Sixty extrashort implants (5 mm in length) were placed in 10 participants. Prosthesis type for each hemimandible was randomly assigned to 1 of 2 groups (n=30): Group NS, nonsplinted crowns and Group S, splinted crowns. Modified plaque index (mPI), modified sulcus bleeding index (mBI), probing pocket depth (PPD), and vertical marginal bone loss (vMBL) were assessed immediately after prosthesis installation (T0) and at 6 (T1), 24 (T2), and 36 months (T3). A custom-made acrylic resin device was used to standardize radiographic images over time, and vMBL was measured by using an image processing software program. Survival rates were analyzed by using the Kaplan-Meier method and the log-rank test. The Mann-Whitney and Friedman tests were used for mPI and mBI, while 2-way repeated-measures ANOVA was applied for PPD and vMBL (α=.05).</p><p><strong>Results: </strong>No significant difference was observed between groups in terms of survival rates, which were 100% and 96.6% for Groups S and NS, respectively (P=.309). The mPI was significantly higher in Group S than in Group NS at T1 (P<.001) and T3 (P=.006). At T3, Group S also exhibited a significantly higher mBI than Group NS (P=.012). PPD was significantly lower in Group S than in Group NS at all time points (P=.038). No significant difference was found between groups regarding vMBL (P=.498). In both groups, vMBL was significantly higher at T1 than at T3 (P=.035).</p><p><strong>Conclusions: </strong>Extrashort implants with nonsplinted crowns exhibited similar survival rates and vMBL compared with those with splinted crowns over a 3-year follow-up period. Extrashort nonsplinted implants were associated with more effective biofilm control.</p>","PeriodicalId":16866,"journal":{"name":"Journal of Prosthetic Dentistry","volume":" ","pages":""},"PeriodicalIF":4.8,"publicationDate":"2025-09-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145000887","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}