Journal of Plastic Surgery and Hand Surgery最新文献_第9页

ADM-assisted prepectoral breast reconstruction is not associated with high complication rate as before: a Meta-analysis. 一项荟萃分析显示，adm辅助的产前乳房重建术不像以前那样与高并发症发生率相关。

IF 1.2 4区医学

Journal of Plastic Surgery and Hand Surgery Pub Date : 2023-02-01 DOI: 10.1080/2000656X.2021.1981351

Jiaheng Xie, Ming Wang, Yuan Cao, Zhechen Zhu, Shujie Ruan, Mengmeng Ou, Pan Yu, Jingping Shi

{"title":"ADM-assisted prepectoral breast reconstruction is not associated with high complication rate as before: a Meta-analysis.","authors":"Jiaheng Xie, Ming Wang, Yuan Cao, Zhechen Zhu, Shujie Ruan, Mengmeng Ou, Pan Yu, Jingping Shi","doi":"10.1080/2000656X.2021.1981351","DOIUrl":"https://doi.org/10.1080/2000656X.2021.1981351","url":null,"abstract":"Implant-related breast reconstruction can be divided into subpectoral breast reconstruction (SPBR) and prepectoral breast reconstruction (PPBR) according to the different anatomical planes. The previous stereotype was that PPBR had a high complication rate and was not suitable for clinical use. However, with the emergence of acellular dermal matrix (ADM), the clinical effect of PPBR has been improved. To compare the outcomes difference between SPBR and PPBR, We conducted this meta-analysis. Articles on SPBR versus PPBR were searched in PubMed, Web of Sciences, Embase, and Cochrane databases, strictly following the PRISMA guidelines. According to the set criteria, we included the literature that met the requirements. Extracted data were the incidence of adverse events and the duration of drainage. Results show that SPBR has a higher incidence rate in capsular contracture, animation deformity, infection, hematoma and delayed healing wound than PPBR. There are no significant differences in skin flap necrosis, seroma, implant loss, reoperation and duration of drainage between the two groups. Hence, PPBR is no longer a high complication surgical method and can be used in the clinical practice. However, there are few large sample studies at present, so it is necessary to carry out further studies on PPBR.","PeriodicalId":16847,"journal":{"name":"Journal of Plastic Surgery and Hand Surgery","volume":"57 1-6","pages":"7-15"},"PeriodicalIF":1.2,"publicationDate":"2023-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10795113","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 12

Loss to follow-up after direct-to-implant breast reconstruction. 直接植入乳房重建术后随访损失。

IF 1.2 4区医学

Journal of Plastic Surgery and Hand Surgery Pub Date : 2023-02-01 DOI: 10.1080/2000656X.2021.1981350

Eun Key Kim, Soo Hyun Woo, Do Yeon Kim, Eun Jeong Choi, Kyunghyun Min, Taik Jong Lee, Jin Sup Eom, Hyun Ho Han

{"title":"Loss to follow-up after direct-to-implant breast reconstruction.","authors":"Eun Key Kim, Soo Hyun Woo, Do Yeon Kim, Eun Jeong Choi, Kyunghyun Min, Taik Jong Lee, Jin Sup Eom, Hyun Ho Han","doi":"10.1080/2000656X.2021.1981350","DOIUrl":"https://doi.org/10.1080/2000656X.2021.1981350","url":null,"abstract":"Loss to follow-up is inevitable in retrospective cohort studies, and patients are lost to follow-up after direct-to-implant reconstruction despite annual follow-up recommendation. We analyzed more than 500 patients to analyze the rate of loss to follow-up to plastic surgery and to investigate the factors affecting it. A retrospective review of patients who underwent direct-to-implant reconstruction between July 2008 and August 2016 was performed. Loss to follow-up to plastic surgery was defined as a difference of <math><mo>≥</mo></math>24 months between the total and plastic surgery follow-up. The rate of loss to follow-up and associated factors including patients' demographics, surgery-related variables, oncological data, and early and late complications were analyzed. Of 631 patients who underwent direct-to-implant reconstruction, 551 patients continued visiting the hospital for breast cancer-related treatment. Of the 527 patients who were eligible for the study, 157 patients (29.8%) were lost to plastic surgery follow-up. Surgery-related variables, early complications, cancer stage, and adjuvant therapies were not significantly different. Younger age was significantly associated with loss to follow-up in univariate analysis. However, logistic regression revealed that a long total follow-up period, distant metastasis, and absence of late elective complications were significant factors contributing to follow-up loss. Late elective complications such as malposition, capsular contracture, and mastectomy flap thinning were more common in the follow-up group (48%) than in the loss to follow-up group (22%). Follow-up loss after direct-to-implant reconstruction was not associated with specific demographic or surgery-related variables, and postoperative courses significantly affected the loss to follow-up.","PeriodicalId":16847,"journal":{"name":"Journal of Plastic Surgery and Hand Surgery","volume":"57 1-6","pages":"64-70"},"PeriodicalIF":1.2,"publicationDate":"2023-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10795787","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

Is conservative management of partial zone II flexor tendon laceration possible? A systematic literature review and meta-analysis. 部分II区屈肌腱撕裂是否可能保守治疗？系统的文献综述和荟萃分析。

IF 1 4区医学

Journal of Plastic Surgery and Hand Surgery Pub Date : 2023-02-01 Epub Date: 2022-10-19 DOI: 10.1080/2000656X.2022.2117704

Young Woong Mo, Da Hye Ryu, Gyo-Young Cho, Jong Won Hong

{"title":"Is conservative management of partial zone II flexor tendon laceration possible? A systematic literature review and meta-analysis.","authors":"Young Woong Mo, Da Hye Ryu, Gyo-Young Cho, Jong Won Hong","doi":"10.1080/2000656X.2022.2117704","DOIUrl":"10.1080/2000656X.2022.2117704","url":null,"abstract":"Background: There is still no consensus on managing zone II level partial flexor tendon lacerations, and the management of zone II partial flexor tendon injuries is controversial. No reliable large cohort studies or metaanalysis papers on partial flexor tendon laceration management are available in PubMed or Embase.Methods: We searched PubMed, Embase, Cochrane Library, Insight, Scopus, and Web of Science databases for primary research articles investigating outcomes of patients with partial flexor tendon injuries. The initial search was limited to human studies that were published from 1970-2021 and indexed as randomized controlled or clinical trials or observational, cross-sectional, or cohort studies. We used statistical package R version 4.1.2 for this meta-analysis.Results: The Standardised mean difference (SMD) of the common effects model was 2.020 (95% CI; 1.583-2.457; P < 0.0001), indicating that the results of conservative treatment without surgical intervention are similar to surgical intervention or better in some articles. The SMD of the random effect model was 7.093 (95% CI; 1.090-13.096; P < 0.0206), indicating the same result. Higgins' I2 value was 97.6%, indicating serious heterogeneity.Conclusions: In this first meta-analysis on flexor zone II conservative treatment, five papers with publication bias were analyzed. It is meaningful to verify the result of conservative treatment statistically. Even though this is a heterogeneous paper, conservative treatment seems to have a lot of benefits for the patient, including offering a fairly solid longterm prognosis with very few complications.","PeriodicalId":16847,"journal":{"name":"Journal of Plastic Surgery and Hand Surgery","volume":"57 1-6","pages":"46-53"},"PeriodicalIF":1.0,"publicationDate":"2023-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10803777","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Systematic review and meta-analysis of the inter-recti distance on ultrasound measurement in nulliparas. 超声测量中直椎间距的系统评价与meta分析。

IF 1 4区医学

Journal of Plastic Surgery and Hand Surgery Pub Date : 2023-02-01 Epub Date: 2022-01-08 DOI: 10.1080/2000656X.2021.2024555

Yue Wang, Huifang Wang

{"title":"Systematic review and meta-analysis of the inter-recti distance on ultrasound measurement in nulliparas.","authors":"Yue Wang, Huifang Wang","doi":"10.1080/2000656X.2021.2024555","DOIUrl":"10.1080/2000656X.2021.2024555","url":null,"abstract":"The objective is to evaluate the inter-recti distance on ultrasound measurement at different locations in healthy nulliparas. Electronic databases were searched for studies describing the inter-recti distance measured by ultrasound in healthy nulliparas. We excluded studies without descriptions of the measurement position or the condition of the abdominal wall. A meta-analysis was performed to evaluate the inter-recti distance on ultrasound measurement. Seven eligible studies with 295 healthy nulliparas were included. The location of the inter-recti distance measurement by ultrasound was not uniform. The pooled data divided the measurement locations into three areas. The meta-analytic summary values of the umbilical inter-recti distance of the nulliparas was 8.77 mm (6.56-10.99 mm), the distance at the epigastric area was 7.22 mm (2.76-11.68 mm), and that at the infraumbilical area was 4.09 mm (1.55-6.64 mm). The maximal reported inter-recti distance in healthy nulliparous women is smaller than 10 mm on ultrasound measurement at all locations and the range in the umbilical area is larger than that in the epigastric, infraumbilical areas. The values for the inter-recti distance reported in this systematic review can be used as the reference of feasible and desirable distance of the rectus muscles after rectus fascia plication. The limitation was that the methodological quality of the assessment in most studies was unclear or low.","PeriodicalId":16847,"journal":{"name":"Journal of Plastic Surgery and Hand Surgery","volume":"57 1-6","pages":"22-28"},"PeriodicalIF":1.0,"publicationDate":"2023-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10795783","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Long-term patient-reported outcomes after anterior distraction osteogenesis of the maxilla in patients with cleft. 腭裂患者上颌前路牵张成骨后的长期患者报告结果。

IF 1.2 4区医学

Journal of Plastic Surgery and Hand Surgery Pub Date : 2023-02-01 DOI: 10.1080/2000656X.2022.2164294

Lina Yasin, Magnus Becker, Henry Svensson, Anna-Paulina Wiedel

{"title":"Long-term patient-reported outcomes after anterior distraction osteogenesis of the maxilla in patients with cleft.","authors":"Lina Yasin, Magnus Becker, Henry Svensson, Anna-Paulina Wiedel","doi":"10.1080/2000656X.2022.2164294","DOIUrl":"https://doi.org/10.1080/2000656X.2022.2164294","url":null,"abstract":"Maxillary growth inhibition in patients with cleft lip and palate (CLP) is an undesired effect that may occur in the teens despite proper primary care. Dental malocclusion and distortion of facial appearance can be treated with external distraction osteogenesis (DO) of the maxilla. This entails a Le Fort I osteotomy, fastening a semi-circular distractor to the skull, distraction for three weeks, and fixation for three months before removal of the device.The aim of this descriptive long-term follow-up study was to evaluate DO of the maxilla from the patient-reported long-term perspective.Fourteen patients underwent a long-term follow-up including a questionnaire regarding their experience of DO. Sex, CLP diagnosis, age at DO and follow-up, and time required for active distraction and fixation were noted. Furthermore, documentation on rhinoplasty, lip plasty and velopharyngeal plasty after DO was registered. Objective results were assessed by a positive dental overjet in the front.Ten patients considered the distractor an everyday constraint, but all thought the procedure was worthwhile and would recommend it to others. Thirteen patients experienced improved bite and chewing, whereas one considered function unchanged. All were satisfied with their dental alignment. Three patients underwent a velopharyngeal plasty after DO. Moreover, six rhinoplasties and two lip plasties were performed.Despite a long and challenging treatment, teenagers and young adults with CLP and maxillary hypoplasia tolerate DO of the maxilla very well. Secondary measures to improve speech and appearance are often indicated.","PeriodicalId":16847,"journal":{"name":"Journal of Plastic Surgery and Hand Surgery","volume":"57 1-6","pages":"488-493"},"PeriodicalIF":1.2,"publicationDate":"2023-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9362110","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Deep wrist injuries from suicide attempts vs. accidents do not differ regarding sensorimotor outcome, but regarding patient-reported outcome measures. 自杀未遂和意外造成的腕部深度损伤在感觉运动结果方面没有差异，但在患者报告的结果测量方面存在差异。

IF 1.2 4区医学

Journal of Plastic Surgery and Hand Surgery Pub Date : 2023-02-01 DOI: 10.1080/2000656X.2021.1993868

Nico Matzkeit, Tobias Kisch, Annika Waldmann, Ulrich Schweiger, Peter Mailänder, Anna Lisa Westermair

{"title":"Deep wrist injuries from suicide attempts vs. accidents do not differ regarding sensorimotor outcome, but regarding patient-reported outcome measures.","authors":"Nico Matzkeit, Tobias Kisch, Annika Waldmann, Ulrich Schweiger, Peter Mailänder, Anna Lisa Westermair","doi":"10.1080/2000656X.2021.1993868","DOIUrl":"https://doi.org/10.1080/2000656X.2021.1993868","url":null,"abstract":"Despite the clinical importance of deep wrist injuries (DWIs), data comparing the outcome of suicide attempt survivors vs. accident survivors are lacking. Patients admitted to our Clinic for acute treatment of a DWI from 2008 to 2016 were contacted for a follow-up assessment of sensory, motor and functional outcomes. Patients also completed the Disability of the Arm, Shoulder and Hand Questionnaire, the Modified Mayo Wrist Score, the Boston Carpal Tunnel Questionnaire, and the WHOQOL-BREF questionnaires. 51 patients could be followed up, on average 4.3 ± 2.9 years after their injury. Suicide attempt survivors did not differ from accidents survivors concerning two-point discrimination, grip and pinch strength, but showed poorer outcomes in self-reported disability, symptom severity, and quality of life. Patients with DWIs from suicide attempts vs. accidents do not differ in sensorimotor outcomes but patient-reported outcome measures. Level of Evidence: II.","PeriodicalId":16847,"journal":{"name":"Journal of Plastic Surgery and Hand Surgery","volume":"57 1-6","pages":"95-102"},"PeriodicalIF":1.2,"publicationDate":"2023-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10795120","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

A comparison of proliferation levels in normal skin, physiological scar and keloid tissue. 正常皮肤、生理性瘢痕和瘢痕疙瘩组织增生水平的比较。

IF 1.2 4区医学

Journal of Plastic Surgery and Hand Surgery Pub Date : 2023-02-01 DOI: 10.1080/2000656X.2021.2017294

Ming-Zi Zhang, Xin-Hang Dong, Wen-Chao Zhang, Ming Li, Lou-Bin Si, Yi-Fang Liu, Hao-Ran Li, Peng-Xiang Zhao, Meng-Yu Liu, Yao Mawulikplimi Adzavon, Xiao-Jun Wang, Xiao Long, Yu Ding

{"title":"A comparison of proliferation levels in normal skin, physiological scar and keloid tissue.","authors":"Ming-Zi Zhang, Xin-Hang Dong, Wen-Chao Zhang, Ming Li, Lou-Bin Si, Yi-Fang Liu, Hao-Ran Li, Peng-Xiang Zhao, Meng-Yu Liu, Yao Mawulikplimi Adzavon, Xiao-Jun Wang, Xiao Long, Yu Ding","doi":"10.1080/2000656X.2021.2017294","DOIUrl":"https://doi.org/10.1080/2000656X.2021.2017294","url":null,"abstract":"Proliferation is an important characteristic of life, and many signaling pathways participate in this complicated process. The MAPK/Erk pathway is a classic pathway in cell proliferation. In this study, expression levels of key factors in the MAPK/Erk pathway were measured to assess the proliferation level among normal skin, physiological scar, and keloid tissue. Thirty patients were selected randomly from the Department of Plastic Surgery at Peking Union Medical College Hospital from January 2019 to December 2020. Histological appearance and fiber tissue content were observed by Hematoxylin and eosin staining and Masson staining. Expression levels of key factors in the MAPK/Erk pathway (ATF2, c-Jun, c-Myc, p38 and STAT1) and relative proteins (HIF-1α and PCNA) in tissues were detected by immunohistochemistry and analyzed as the percentage of positively stained cells in both the tissue epidermis and dermis. Western blot was used for quantitative analysis of the above factors. In results, keloid tissue showed a significantly higher fiber and less cell content. In the immunohistochemical result, higher expression of key factors was observed in the epidermis than in the dermal layer, and the expression of all factors was increased remarkably in keloid tissue. In western blot analysis, all factors (except STAT1) showed higher expression in keloid tissue. In our former research, keloid showed similar apoptosis level as physiological scar and normal skin. On combining our former conclusion and results in this study, an imbalance condition between the high proliferation level and normal apoptosis level may lead to the growth characteristics of keloid.","PeriodicalId":16847,"journal":{"name":"Journal of Plastic Surgery and Hand Surgery","volume":"57 1-6","pages":"122-128"},"PeriodicalIF":1.2,"publicationDate":"2023-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10796883","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 5

Scar versus shape: patient-reported outcome after different surgical approaches to gynecomastia measured by modified BREAST Q®. 疤痕与形状:改良BREAST Q®测量的不同手术入路后患者报告的结果。

IF 1.2 4区医学

Journal of Plastic Surgery and Hand Surgery Pub Date : 2023-02-01 DOI: 10.1080/2000656X.2021.1981349

Anna Burger, Amelie Sattler, Lisanne Grünherz, Pietro Giovanoli, Nicole Lindenblatt, Ulrich Michael Rieger

{"title":"Scar versus shape: patient-reported outcome after different surgical approaches to gynecomastia measured by modified BREAST Q®.","authors":"Anna Burger, Amelie Sattler, Lisanne Grünherz, Pietro Giovanoli, Nicole Lindenblatt, Ulrich Michael Rieger","doi":"10.1080/2000656X.2021.1981349","DOIUrl":"https://doi.org/10.1080/2000656X.2021.1981349","url":null,"abstract":"Objectives: The challenge in the operative therapy for enlargement of the male breast is to deal with the skin excess. Shape and scars are the major parameters after which patients assess their operative result. Therefore, we assessed the satisfaction rate among patients undergoing subcutaneous mastectomy at our institution with special regard to scar tissue formation and the postoperative appearance of the chest wall in dependence of the surgical approach (periarolar versus inframammary fold).Methods: The study includes n = 36 male patients who underwent subcutaneous mastectomy at AGAPLESION Markus Hospital Frankfurt/Main. Patient's satisfaction dependent with the appearance of the chest wall and scar formation was evaluated by a modified BREAST Q® questionnaire plus two male-based additional questions.Results: There is no statistically significant difference in satisfaction with the operative result depending on the pattern of incision (periareolar versus submammary periareolar; 81.9% versus 75.5%) with the operative result. Evaluation of additional questions of the modified BREAST Q® questionnaire showed that 86% of the patients (n = 31) would rather have more scars and a flatter chest wall. A BMI >25 kg/m2 is accompanied by a higher risk for complications (p = 0.04).Conclusions: Periareolar incision is still the method of choice, if promising an aesthetic appealing result. When reaching its limits though, we showed that a flat and male-shaped appearance of the chest wall is priority for the patients and should therefore be for the surgeon as well.","PeriodicalId":16847,"journal":{"name":"Journal of Plastic Surgery and Hand Surgery","volume":"57 1-6","pages":"1-6"},"PeriodicalIF":1.2,"publicationDate":"2023-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10802046","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Efficacy of stromal vascular fraction and enzyme-free mechanical isolation therapy in experimental full thickness burn wounds. 基质血管组分和无酶机械隔离治疗实验性全层烧伤创面的疗效。

IF 1.2 4区医学

Journal of Plastic Surgery and Hand Surgery Pub Date : 2023-02-01 DOI: 10.1080/2000656X.2021.1993234

Percin Karakol, Mehmet Bozkurt, Caner Gelbal, Mehmet Ibrahim Tuglu

{"title":"Efficacy of stromal vascular fraction and enzyme-free mechanical isolation therapy in experimental full thickness burn wounds.","authors":"Percin Karakol, Mehmet Bozkurt, Caner Gelbal, Mehmet Ibrahim Tuglu","doi":"10.1080/2000656X.2021.1993234","DOIUrl":"https://doi.org/10.1080/2000656X.2021.1993234","url":null,"abstract":"Background: Autologous cell suspensions obtained by a stromal vascular fraction (SVF) and enzyme-free mechanical isolation (EMI) are an alternative in the treatment of burn wounds. In this study, we aimed to investigate the effect of autologous cell suspensions obtained by SVF and EMI on full-thickness skin burn wounds.Methods: A total of 45 male Sprague-Dawley rats were divided into three groups, SVF group, EMI group, and SVF + EMI group. The groups were also classified as the first, second, and third week of the burn to reveal the effect of the treatment on the burn in the early, middle, and late stages. For treatment, 0.2 ml SVF or 0.2 ml EMI was injected subcutaneously into the burn lesions of the subjects. Histopathological examination was performed on the burn wounds taken at the end of the experiment, and Ki67, CD44, CD73, CD90, and CK17 expressions were evaluated.Results: Histological examination revealed that there was no improvement in the control samples, but the skin was multicellular, vascularization was present. Histologic scores in all groups was significantly better than control, and SVF + EMI was the best group in terms of recovery (p < 0.05). Ki67, CK17, CD44, CD73, and CD90 expressions were significantly higher in the treatment groups compared to the control (p < 0.05).Conclusion: We found in our study that both applications significantly increased the healing of the burn wound. Moreover, SVF + EMI application provided more improvement than SVF or EMI alone.","PeriodicalId":16847,"journal":{"name":"Journal of Plastic Surgery and Hand Surgery","volume":"57 1-6","pages":"78-94"},"PeriodicalIF":1.2,"publicationDate":"2023-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10852799","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 4

The impact of regional anesthesia on opioid demand in distal radius fracture surgery. 区域麻醉对桡骨远端骨折手术中阿片类药物需求的影响。

IF 1.2 4区医学

Journal of Plastic Surgery and Hand Surgery Pub Date : 2023-02-01 DOI: 10.1080/2000656X.2022.2070178

Daniel Cunningham, Micaela LaRose, Tori Kinamon, Elle MacAlpine, Sandra Au, Ariana Paniagua, Christopher Klifto, Mark J Gage

{"title":"The impact of regional anesthesia on opioid demand in distal radius fracture surgery.","authors":"Daniel Cunningham, Micaela LaRose, Tori Kinamon, Elle MacAlpine, Sandra Au, Ariana Paniagua, Christopher Klifto, Mark J Gage","doi":"10.1080/2000656X.2022.2070178","DOIUrl":"https://doi.org/10.1080/2000656X.2022.2070178","url":null,"abstract":"Purpose: Regional anesthesia (RA) is commonly used in distal radius fracture surgery to reduce pain and opioid consumption. The purpose of this study was to evaluate the real-world impact of RA on inpatient and outpatient opioid consumption and demand in patients undergoing distal radius fracture surgery.Methods: All patients ages 18 and older undergoing distal radius fracture surgery between 7/2013 and 7/2018 at a single institution (n = 969) were identified. Inpatient opioid consumption and outpatient opioid prescribing in oxycodone 5-mg equivalents (OE's) up to 90-d post-operative were recorded for patients with and without RA. Adjusted models were used to evaluate the impact of RA on opioid outcomes.Results: Adjusted models demonstrated decreases in inpatient opioid consumption in patients with RA (10.7 estimated OE's without RA vs. 7.6 OE's with RA from 0 to 24 h post-op, 10.2 vs. 5.3 from 24 to 48 h post-op and 7.5 vs. 5.0 from 48 to 72 h post-op, p<.05). Estimated cumulative outpatient opioid demand was significantly higher in patients with RA (65.3 OE's without RA vs. 81.0 with RA from 1-month pre-op to 2-week post-discharge, 76.1 vs. 87.7 OE's to 6-weeks, and 80.8 vs. 93.5 OE's to 90-d, all p values for RA <.05) though rates of refill were significantly lower in patients with RA from 2-week to 6-week post-op compared to patients without RA.Conclusions: Patients undergoing RA in distal radius fracture surgery had decreased inpatient opioid consumption but increased outpatient demand after adjustment for patient and operative characteristics.Level of evidence: Level III, retrospective, therapeutic cohort study.","PeriodicalId":16847,"journal":{"name":"Journal of Plastic Surgery and Hand Surgery","volume":"57 1-6","pages":"299-307"},"PeriodicalIF":1.2,"publicationDate":"2023-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10853329","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1