Salem Rashed Almutairi, Bander Shehail Alshammeri, Anas S A Aldakhili
{"title":"The Combating Impact of Biogenic Silver Nano Particles and Antibiotics on Combating Multidrug-Resistant Pseudomonas","authors":"Salem Rashed Almutairi, Bander Shehail Alshammeri, Anas S A Aldakhili","doi":"10.55529/jcpp.34.12.26","DOIUrl":"https://doi.org/10.55529/jcpp.34.12.26","url":null,"abstract":"This study aimed to assess the synergistic effect of silver nanoparticles (AgNPs) in combination with different antibiotics against multidrug-resistant Pseudomonas aeruginosa (MDR P. aeruginosa) infections. A total of 120 surgical or burn wound samples were collected from a tertiary care hospital. The samples were cultured on cetrimide agar plates and then heated to 370 degrees Celsius. The isolates were identified based on colony shape, Gram's staining, and various biochemical tests. The antibiotic susceptibility profile was determined using the Kirby-Bauer disc diffusion technique according to CLSI 2022 recommendations. Minimum inhibitory concentration (MIC) and minimum bactericidal concentration (MBC) were also determined. The antibacterial activity of AgNPs was evaluated using the agar well diffusion technique and the microdilution method. The synergistic effect of antibiotics and AgNPs was assessed using the Checkerboard method. Out of the 120 samples, 46 (38.8%) were confirmed as positive for P. aeruginosa, and among them, 33 were identified as MDR P. aeruginosa. Seven representative isolates were selected for further analysis. The antibacterial activity of AgNPs showed a maximum zone of inhibition of 12mm at 4mg/ml and a minimum of 2.5mm at 1mg/ml using the agar well diffusion method. The MIC and MBC of AgNPs indicated that all isolates were inhibited at a concentration of 250mg/ml. The Checkerboard results revealed that colistin and gentamicin exhibited complete synergism with AgNPs, while ciprofloxacin showed partial synergism with AgNPs.","PeriodicalId":16825,"journal":{"name":"Journal of Pharmacy Practice and Community Medicine","volume":"17 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-07-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"83018706","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Hansraj Bishnoi, Dr. Hariom Sharma, Dr. Shailesh Sharma, S. Sharma, Shreyasi Shreyasi
{"title":"Pharmacological Properties of Lagenaria Siceraria","authors":"Hansraj Bishnoi, Dr. Hariom Sharma, Dr. Shailesh Sharma, S. Sharma, Shreyasi Shreyasi","doi":"10.55529/jcpp.35.1.11","DOIUrl":"https://doi.org/10.55529/jcpp.35.1.11","url":null,"abstract":"Lagenaria siceraria (LS), more commonly referred to as ‘bottle gourd’, is a type of vegetable that is widely cultivated and has several properties that have potential medical applications. The purpose of this review article is to provide a general summary of the pharmacological activities of L. siceraria that have been reported in a variety of investigations. The literature search was carried out by using a variety of databases, such as PubMed, Scopus, and Web of Science, along with keywords that were pertinent to the topic. This paper provides a concise summary of what is currently known about the pharmacological capabilities of L. siceraria, including its anticonvulsant, neuroprotective, hepatoprotective, hypoglycemic, antidiabetic, anticancer, and antimicrobial activity. This study alsomakes recommendations for the paths of future research. In conclusion, L. siceraria has shown a great deal of promise as a source of naturally occurring bioactive chemicals that have the potential to be exploited in the production of innovative pharmaceuticals as well as functional foods.","PeriodicalId":16825,"journal":{"name":"Journal of Pharmacy Practice and Community Medicine","volume":"42 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-06-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"75580089","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Sadia Sehar, N. ul Haq, M. Tahir, S. Riaz, A. Nasim, Muhammad Saood, R. Yasmin
{"title":"Impact of Treatment on Asthma Control in Quetta Pakistan","authors":"Sadia Sehar, N. ul Haq, M. Tahir, S. Riaz, A. Nasim, Muhammad Saood, R. Yasmin","doi":"10.5530/jppcm.2023.1.1","DOIUrl":"https://doi.org/10.5530/jppcm.2023.1.1","url":null,"abstract":"","PeriodicalId":16825,"journal":{"name":"Journal of Pharmacy Practice and Community Medicine","volume":"11 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-03-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"74439379","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Majid Khan, Madiha Arslan, Muhammad Usman Amin, A. Khan
{"title":"Vitamin D3 Analogues and Laboratory Tests Interactions: Public Health Awareness Glance","authors":"Majid Khan, Madiha Arslan, Muhammad Usman Amin, A. Khan","doi":"10.5530/jppcm.2023.1.2","DOIUrl":"https://doi.org/10.5530/jppcm.2023.1.2","url":null,"abstract":"","PeriodicalId":16825,"journal":{"name":"Journal of Pharmacy Practice and Community Medicine","volume":"2 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-03-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"88748992","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Anti-Cancer of Leaves Extracts of Christ's thorn Jujube in Muthanna Province against Human Cervix Carcinoma Cells Line in Vitro","authors":"H. Khayoon","doi":"10.55529/jcpp.32.1.8","DOIUrl":"https://doi.org/10.55529/jcpp.32.1.8","url":null,"abstract":"Rhamnaceae plants have been demonstrated to have anticancer properties. In this study, we investigated the cytotoxic potential of the leaves of the species from this family, Christ's thorn Jujube (C.T.J.), on cancer cell lines. The viability of HeLa cells (human cervix carcinoma cells) was significantly and concentration-dependently decreased by hexane and aqueous extracts of the leaves of Christ's thorn Jujube. The leaf extract from Christ's thorn Jujube was more effective than the other extracts in both cell lines. The results of this study suggest that Christ's thorn jujube is a promising candidate for further research into potential new cytotoxic agents.","PeriodicalId":16825,"journal":{"name":"Journal of Pharmacy Practice and Community Medicine","volume":"7 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-02-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"81699185","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"A Case Report on Hereditary Spherocytosis in a 22-Year-Old Female","authors":"Umme Habeeba A Pathan","doi":"10.5530/jppcm.2022.4.13","DOIUrl":"https://doi.org/10.5530/jppcm.2022.4.13","url":null,"abstract":"gallstones","PeriodicalId":16825,"journal":{"name":"Journal of Pharmacy Practice and Community Medicine","volume":"147 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"75996391","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Recommended Dietary Measures in the Management and Prevention of Type 2 Diabetes Mellitus","authors":"I. Abubakar, Jibo Garba Abdulrahman","doi":"10.5530/jppcm.2022.4.12","DOIUrl":"https://doi.org/10.5530/jppcm.2022.4.12","url":null,"abstract":"","PeriodicalId":16825,"journal":{"name":"Journal of Pharmacy Practice and Community Medicine","volume":"47 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"86608894","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Dr. M. R. Prakash, Mrs. G. Madhuri, Mrs. A. Subhasri M, Ms. K. Agilandeswari
{"title":"A Customer Perception of Planet Healthcare Pharmacy","authors":"Dr. M. R. Prakash, Mrs. G. Madhuri, Mrs. A. Subhasri M, Ms. K. Agilandeswari","doi":"10.55529/jcpp.26.1.3","DOIUrl":"https://doi.org/10.55529/jcpp.26.1.3","url":null,"abstract":"Retailing, it is a developing pattern in the India. In India the retail business has turned into the second biggest boss after farming. The Indian retail market is the 5th biggest retail destination all around. It is assessed to develop from the US $ 266 billion in 2005 to US $ 435 billion by 2010 and US $ 587 billion by 2015. The passage of composed players is changing the substance of the drug store business, which today is exceedingly divided. The retail side too has been posting high development rates. \"The aggregate retail drug store business sector will be developing at a rate of around 15 for every penny, while sorted out the retail drug store will be seeing a development of anyplace somewhere around 35 and 40 for every penny,\" as indicated by Technopak Consultants. In addition, the high edges – somewhere around 25 and 35 %.","PeriodicalId":16825,"journal":{"name":"Journal of Pharmacy Practice and Community Medicine","volume":"35 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-11-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"81288490","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
S. Tripathi, Vaibhav Dubey, Alok Semwal, Ratan B Chaturvedi, Vishal Musale, K. Narain
{"title":"A Review on Futuristic Scope of Agents Related to Amphibian’s Skin and Plants-based Sources in Type 2 Antidiabetic Therapies","authors":"S. Tripathi, Vaibhav Dubey, Alok Semwal, Ratan B Chaturvedi, Vishal Musale, K. Narain","doi":"10.5530/jppcm.2022.3.9","DOIUrl":"https://doi.org/10.5530/jppcm.2022.3.9","url":null,"abstract":"","PeriodicalId":16825,"journal":{"name":"Journal of Pharmacy Practice and Community Medicine","volume":"39 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-09-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"83895356","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Effect of Exercise on Drug Absorption","authors":"I. Abubakar, Jibo Garba Abdulrahman","doi":"10.5530/jppcm.2022.3.11","DOIUrl":"https://doi.org/10.5530/jppcm.2022.3.11","url":null,"abstract":"For drugs administered orally, Drug absorption majorly takes place in the small intestine, with gastric emptying as a limiting step.[2] Exercise influences several physiological functions which may affect the absorption of drugs from small intestine, it as well redistributes cardiac output away from the splanchnic region, most likely due to increased sympathetic nervous activity.[1] Throughout the exercise period, there is decrease in pH of blood and muscle due to formation of lactic acid and this may alter drug ionization and polarity.[3] Increased sympathetic tone and the release of catecholamine’s during vigorous exercise are responsible for the inhibition of gastric emptying and this depends on the exercise conditions.[4] Regular exercise that last more than 1 hr will significantly delays gastric emptying and increases the frequency and amplitude of contractions in the duodenum.[5]","PeriodicalId":16825,"journal":{"name":"Journal of Pharmacy Practice and Community Medicine","volume":"124 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-09-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"77351527","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}