Krishnagiri Krishnababu, Gururaj S. Kulkarni, Athmaja Shetty, Yogaraj R., Rakesh Babu S. N.
{"title":"Development of Micro/Nanobots and their Application in Pharmaceutical and Healthcare Industry","authors":"Krishnagiri Krishnababu, Gururaj S. Kulkarni, Athmaja Shetty, Yogaraj R., Rakesh Babu S. N.","doi":"10.55529/jmhib.36.1.12","DOIUrl":"https://doi.org/10.55529/jmhib.36.1.12","url":null,"abstract":"The subject of molecular robotics is expanding quickly, and a novel approach to treating human illness or problems involves shrinking nanobots or robotics to the nanometer scale. Researchers are focusing on the various possible uses of nanorobots in medicine and therapy since they are a sophisticated technology that has the potential to change people's lives. Nowadays, modern procedures are mostly employed to create nanobots, which has improved the negative effects of nanobots. This review deals with the overview and future aspects of nanorobotics in the pharmaceutical field, medical uses, biocompatibility, and toxicity of nanobots.","PeriodicalId":16825,"journal":{"name":"Journal of Pharmacy Practice and Community Medicine","volume":"41 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-10-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"136013936","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Spotlight on Neutralizing Antibodies of Mrna-1273 and BNT162b2 Mrna Vaccines against SARS-Cov 2 Omicron","authors":"Ramdas Bhat, Preeti Shanbhag","doi":"10.55529/jcpp.35.38.46","DOIUrl":"https://doi.org/10.55529/jcpp.35.38.46","url":null,"abstract":"The emergence of the Omicron variant of SARS-CoV-2 has raised concerns about the effectiveness of existing COVID-19 vaccines. Initially, spike protein was identified as a key target for vaccine development, leading to the creation of mRNA vaccines like Pfizer-BioNTech and Moderna, which have shown high efficacy. The immune response to SARS-CoV-2 involves both innate and adaptive systems, with B and T lymphocytes playing crucial roles. Protein-based subunit vaccines have also demonstrated effectiveness. However, the ongoing evolution of the virus necessitates the exploration of strategies such as developing new vaccines, updating existing ones, and administering booster shots. Ongoing research and adaptation of vaccination strategies are essential in the battle against COVID-19.","PeriodicalId":16825,"journal":{"name":"Journal of Pharmacy Practice and Community Medicine","volume":"102 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-09-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135083380","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Mucoadhesive Buccal Films","authors":"Yuktha H J, Gururaj S Kulkarni, Padmaa M Paarak","doi":"10.55529/jcpp.35.24.37","DOIUrl":"https://doi.org/10.55529/jcpp.35.24.37","url":null,"abstract":"Pharmaceutical formulations are experiencing a significant transformation as novel drug delivery techniques become increasingly available and effective. While there are many different types of medical dosage forms, each has its own limitations, such as tablet choking and painful parenteral dosages. Buccal drug delivery, which involves administering medication to the oral cavity, offers a convenient and easy-to-administer alternative. The oral route of medication administration has numerous benefits, including avoiding liver metabolism, enhancing drug bioavailability, and improving the onset of action. By directly entering the systemic circulation, active pharmaceutical ingredients can produce their therapeutic effects. As the buccal mucosa has a high degree of permeability and blood supply, it is a highly accessible drug delivery system. There are six theories that explain mucosal adhesion: electronics, wettability, adsorption, degradation, diffusion, and mechanics. Various in vitro and in vivo approaches have been used to study buccal drug delivery systems. This paper discusses the mechanisms of action, mucosal adhesion theories, and standard techniques for producing films. Key areas of study in buccal drug delivery systems include evaluating films for weight variation, thickness, folding endurance, surface pH, percentage of moisture absorption and loss, tensile strength, swelling index, content uniformity, and in vitro permeation studies.","PeriodicalId":16825,"journal":{"name":"Journal of Pharmacy Practice and Community Medicine","volume":"10 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-09-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135083093","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Survey to Asses Iraqi Pharmacists Information about Acetaminophen","authors":"Zainab Mustafa Mahdi","doi":"10.55529/jcpp.35.15.23","DOIUrl":"https://doi.org/10.55529/jcpp.35.15.23","url":null,"abstract":"Background: Paracetamol/acetaminophen is sold over-the-counter in both mono- and multi-component formulations. It is among the most popular and widely used analgesic and antipyretic medications in the world. Those who cannot be treated with non-steroidal anti-inflammatory (NSAID). Medicines are advised to use it. The purpose of the current study was to examine and appraise pharmacists in Iraq's knowledge of the most popular medicine, acetaminophen. Method: By posting a Google form on social media, whatsapp, and telegram and sending the link to all the medical groups of pharmacists, the survey research's data was gathered on October 29, 2021. We asked the Iraqi pharmacists 16 questions, 12 of which were regarding their knowledge of acetaminophen. Four of the questions concerned the pharmacists' characteristics (age, gender, degree, and government). On February 1, 2022, the survey research came to an end Results: The researches received 145 surveys from different Iraqi Governorates. Twenty to thirty years old make up 97%. 56.6 percent of respondents thought acetaminophen placed future fetuses at risk for ADHD, whereas 43.4 percent actually thought it did. 34.5 percent agreed that chronic acetaminophen usage by pregnant women is safe for the fetus, compared to 65.5 percent who disagreed. While 16.6 percent of respondents disagreed, 83.4 percent of respondents said acetaminophen was safe for expectant mothers. Conclusion: Most pharmacists had not good information about mechanism of acetaminophen action, while they knew that Acetaminophen active metabolite (APAP) cause liver damage. The study had been showed that most pharmacist were aware about OTC medication .However, about one-third of them had inadequate knowledge of how acetaminophen affects the fetus and may result in ADHD in addition to other acetaminophen indications","PeriodicalId":16825,"journal":{"name":"Journal of Pharmacy Practice and Community Medicine","volume":"32 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-09-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"136336295","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Impact of Government Policy and Socio-Economic Hardship on Stroke Re-Occurrence","authors":"A. Gordons, Yusuff Tunde Gbonjubola","doi":"10.5530/jppcm.2023.2.6","DOIUrl":"https://doi.org/10.5530/jppcm.2023.2.6","url":null,"abstract":"","PeriodicalId":16825,"journal":{"name":"Journal of Pharmacy Practice and Community Medicine","volume":"19 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-08-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"74440701","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Saliu Akeem Olanrewaju, Ogwumike O. Omoyemi, Yusuff Tunde Gbonjubola, Alexander E. Gordons3
{"title":"Effect of Concurrent Co-Morbidity in the Management of Musculoskeletal Disorders","authors":"Saliu Akeem Olanrewaju, Ogwumike O. Omoyemi, Yusuff Tunde Gbonjubola, Alexander E. Gordons3","doi":"10.5530/jppcm.2023.2.3","DOIUrl":"https://doi.org/10.5530/jppcm.2023.2.3","url":null,"abstract":"","PeriodicalId":16825,"journal":{"name":"Journal of Pharmacy Practice and Community Medicine","volume":"18 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-08-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"75738978","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Neelakanthayyaswamy I Hiremath, R. Kangle, Ashwini Narasannavar
{"title":"Knowledge, Attitude and Practice of Brucellosis among Farmers Rearing Cattle in Belagavi Taluka - A One Year Cross-sectional Study","authors":"Neelakanthayyaswamy I Hiremath, R. Kangle, Ashwini Narasannavar","doi":"10.5530/jppcm.2023.2.4","DOIUrl":"https://doi.org/10.5530/jppcm.2023.2.4","url":null,"abstract":"","PeriodicalId":16825,"journal":{"name":"Journal of Pharmacy Practice and Community Medicine","volume":"9 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-08-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"88391780","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Sanjay Silawat, V. Verma, Praveen Yuwane, Shivam Dixit
{"title":"A Community Based Study on Various Aspects of Breast-Feeding Practices from Central India","authors":"Sanjay Silawat, V. Verma, Praveen Yuwane, Shivam Dixit","doi":"10.5530/jppcm.2023.2.5","DOIUrl":"https://doi.org/10.5530/jppcm.2023.2.5","url":null,"abstract":"","PeriodicalId":16825,"journal":{"name":"Journal of Pharmacy Practice and Community Medicine","volume":"131 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-08-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"84744680","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Investigation of Acute Toxicity and Biological Activity of an Extract obtained on the Basis of a Local Medicinal Herbal Collection","authors":"Akhranova Sokhiba Tazhidinovna","doi":"10.55529/jcpp.35.8.14","DOIUrl":"https://doi.org/10.55529/jcpp.35.8.14","url":null,"abstract":"The presented article describes the results of research work on the alimentary and hemolytic anemic effect of herbal decoction of medicinal properties, which is used in folk medicine for the treatment of various diseases. The extract of the sum of decoctions of medicinal plants was administered orally to experimental rabbits for 60 days in an amount of 10 ml / kg and 25 ml / kg, and their antianemic activity was assessed by such indicators as the number of shaped blood elements, as well as the general condition of experimental animals and changes in weight. Extract of tincture of sum of medicinal plants in studies of therapeutic effect in alimentary anemia on the other hand, already on the 7th day of treatment, the effect against hemolytic anemia began to manifest itself in less than 21 days, and it becomes more intense until the end of the experiment. These effects were manifested by a positive change in the number of shaped blood elements, an improvement in the general condition of experimental animals, a significant increase in appetite, and the restoration of lost body weight. This entails extensive scientific studies of the activity and mechanism of action of this tincture against the background of various anemia.","PeriodicalId":16825,"journal":{"name":"Journal of Pharmacy Practice and Community Medicine","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-08-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"90374935","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
A. O. Solesi, R. Sowole, H. N. Adetoyi, B. A. Odugbemi
{"title":"Evaluation of Incidence of Asymptomatic Plasmodium Falciparum in a Peri-Urban Community in Ogun, Nigeria","authors":"A. O. Solesi, R. Sowole, H. N. Adetoyi, B. A. Odugbemi","doi":"10.55529/jcpp.35.1.7","DOIUrl":"https://doi.org/10.55529/jcpp.35.1.7","url":null,"abstract":"Malaria has been a public health concern in most tropical and sub-tropical countries around the world with causative agents by five Plasmodium species. Malaria is a prominent disease of high-temperature regions with high morbidity, leading to socio-economic loss. Pregnancy asymptomatic Plasmodium species infection causes placental infection and anaemia; separation of infected red blood cells in the mother intervillous spaces of the placenta resulted in its infection and is associated with placental inflammation and fibrosis. Screening for individuals with asymptomatic infections to determine their prevalence and possibly control it is pertinent using sensitive cum precise diagnostic tools. This study aim's at evaluating the incidence of asymptomatic plasmodium falciparum in the study area. Two hundred and ten blood samples were collected randomly from Ogun State Polytechnic of Health and Allied Science, Ilese Campus; this constituted students and staffers with asymptomatic Plasmodium falciparum between February and March 2023. The students and staffers exhibiting any symptoms of Malaria infection, such as fever, nausea, chills, etc., and on anti-malaria drugs were excluded from the tested population. The male volunteer was 15.2% (32/ 210) while the female was 84.8%, reflecting the nature of the population's gender skewness being a female-dominated place. The age distribution, 17-26 years age group was high with 59%; 27-36 was 13.8%, 37-46 with 17.6%, 47-56; 7.6%, 57-65+ being lowest with 1.9%. The prevalence of plasmodium falciparum in the blood of subjects in this study was 87%; the male infected was 18%, and the female was 68.6%.","PeriodicalId":16825,"journal":{"name":"Journal of Pharmacy Practice and Community Medicine","volume":"25 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-08-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"83392360","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}