{"title":"从当地草药中提取的提取物的急性毒性和生物活性的研究","authors":"Akhranova Sokhiba Tazhidinovna","doi":"10.55529/jcpp.35.8.14","DOIUrl":null,"url":null,"abstract":"The presented article describes the results of research work on the alimentary and hemolytic anemic effect of herbal decoction of medicinal properties, which is used in folk medicine for the treatment of various diseases. The extract of the sum of decoctions of medicinal plants was administered orally to experimental rabbits for 60 days in an amount of 10 ml / kg and 25 ml / kg, and their antianemic activity was assessed by such indicators as the number of shaped blood elements, as well as the general condition of experimental animals and changes in weight. Extract of tincture of sum of medicinal plants in studies of therapeutic effect in alimentary anemia on the other hand, already on the 7th day of treatment, the effect against hemolytic anemia began to manifest itself in less than 21 days, and it becomes more intense until the end of the experiment. These effects were manifested by a positive change in the number of shaped blood elements, an improvement in the general condition of experimental animals, a significant increase in appetite, and the restoration of lost body weight. This entails extensive scientific studies of the activity and mechanism of action of this tincture against the background of various anemia.","PeriodicalId":16825,"journal":{"name":"Journal of Pharmacy Practice and Community Medicine","volume":"1 1","pages":""},"PeriodicalIF":0.0000,"publicationDate":"2023-08-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Investigation of Acute Toxicity and Biological Activity of an Extract obtained on the Basis of a Local Medicinal Herbal Collection\",\"authors\":\"Akhranova Sokhiba Tazhidinovna\",\"doi\":\"10.55529/jcpp.35.8.14\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"The presented article describes the results of research work on the alimentary and hemolytic anemic effect of herbal decoction of medicinal properties, which is used in folk medicine for the treatment of various diseases. The extract of the sum of decoctions of medicinal plants was administered orally to experimental rabbits for 60 days in an amount of 10 ml / kg and 25 ml / kg, and their antianemic activity was assessed by such indicators as the number of shaped blood elements, as well as the general condition of experimental animals and changes in weight. Extract of tincture of sum of medicinal plants in studies of therapeutic effect in alimentary anemia on the other hand, already on the 7th day of treatment, the effect against hemolytic anemia began to manifest itself in less than 21 days, and it becomes more intense until the end of the experiment. These effects were manifested by a positive change in the number of shaped blood elements, an improvement in the general condition of experimental animals, a significant increase in appetite, and the restoration of lost body weight. This entails extensive scientific studies of the activity and mechanism of action of this tincture against the background of various anemia.\",\"PeriodicalId\":16825,\"journal\":{\"name\":\"Journal of Pharmacy Practice and Community Medicine\",\"volume\":\"1 1\",\"pages\":\"\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2023-08-17\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Journal of Pharmacy Practice and Community Medicine\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.55529/jcpp.35.8.14\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Journal of Pharmacy Practice and Community Medicine","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.55529/jcpp.35.8.14","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 0
摘要
本文介绍了民间医学中用于治疗多种疾病的中药汤剂的消化和溶血贫血作用的研究成果。将药用植物煎剂和提取物分别以10 ml / kg和25 ml / kg的剂量口服实验家兔60 d,通过形血元素数、实验动物一般情况和体重变化等指标评价其抗贫血活性。另一方面,从治疗的第7天开始,在不到21天的时间里,对溶血性贫血的治疗效果就开始显现,并在实验结束前变得更加强烈。这些效果表现在形血元素数量的积极变化,实验动物的一般状况的改善,食欲的显着增加以及体重的恢复。这就需要对这种酊剂在各种贫血背景下的活性和作用机制进行广泛的科学研究。
Investigation of Acute Toxicity and Biological Activity of an Extract obtained on the Basis of a Local Medicinal Herbal Collection
The presented article describes the results of research work on the alimentary and hemolytic anemic effect of herbal decoction of medicinal properties, which is used in folk medicine for the treatment of various diseases. The extract of the sum of decoctions of medicinal plants was administered orally to experimental rabbits for 60 days in an amount of 10 ml / kg and 25 ml / kg, and their antianemic activity was assessed by such indicators as the number of shaped blood elements, as well as the general condition of experimental animals and changes in weight. Extract of tincture of sum of medicinal plants in studies of therapeutic effect in alimentary anemia on the other hand, already on the 7th day of treatment, the effect against hemolytic anemia began to manifest itself in less than 21 days, and it becomes more intense until the end of the experiment. These effects were manifested by a positive change in the number of shaped blood elements, an improvement in the general condition of experimental animals, a significant increase in appetite, and the restoration of lost body weight. This entails extensive scientific studies of the activity and mechanism of action of this tincture against the background of various anemia.