Journal of Pharmacopolium最新文献_第8页

IDENTIFIKASI TARGET RESEPTOR SENYAWA 10,11-DIHIDROERISODIN SEBAGAI KANDIDAT ANTIKANKER SECARA IN SILICO 鉴定目标化合物1011 -淋巴细胞素为硅胶抗癌候选人

Journal of Pharmacopolium Pub Date : 2018-09-03 DOI: 10.36465/JOP.V1I1.393

Srie Rezeki Nur Endah

引用次数: 1

IDENTIFIKASI BAKTERI POTENSIAL PADA FASE PEMATANGAN KOMPOS MANUR 在堆肥成熟阶段识别潜在的细菌

Journal of Pharmacopolium Pub Date : 2018-09-03 DOI: 10.36465/jop.v1i1.390

Fenti Fatmawati

引用次数: 1

FATTY ACID ANALYSIS OF MARINE MICROALGAE Chlorella Sp. IN MODIFIED MEDIUM USED GAS CRHOMATOGRAPHY-MASS SPECTROMETRY (GC-MS) 改良培养基中海洋微藻小球藻脂肪酸的气相色谱-质谱联用分析

Journal of Pharmacopolium Pub Date : 2018-09-03 DOI: 10.36465/JOP.V1I1.389

D. Kurnia

引用次数: 3

SKRINING AKTIVITAS ANTIBAKTERI FRAKSI EKSTRAK ETANOL KERNEL BIJI BUAH LIMUS (Mangifera foetida Lour.) TERHADAP Staphylococcus aureusDAN Escherichia coli 提取利尿剂果实果实内核的乙醇成分的抗菌活性。杆菌杆菌

Journal of Pharmacopolium Pub Date : 2018-09-03 DOI: 10.36465/JOP.V1I1.394

Vera Nurviana

{"title":"SKRINING AKTIVITAS ANTIBAKTERI FRAKSI EKSTRAK ETANOL KERNEL BIJI BUAH LIMUS (Mangifera foetida Lour.) TERHADAP Staphylococcus aureusDAN Escherichia coli","authors":"Vera Nurviana","doi":"10.36465/JOP.V1I1.394","DOIUrl":"https://doi.org/10.36465/JOP.V1I1.394","url":null,"abstract":"Limus (Mangifera foetida Lour.) Is one of the local Indonesian fruits of the anacardiaceae family. Limus contain secondary metabolites that have pharmacological effects, including the kernel waste of the seeds of the fruit. This study aims to determine the antibacterial activity against Staphylococcus aureus and Escherichia coli on the fraction of kernel seed of limus fruits ethanolic extract in invitro using solid diffusion method with positive control Tetracycline HCl. The extraction process was carried out by maceration method, then fractionation was obtained to obtain the fraction of n-hexane, ethyl acetate fraction and water fraction. Based on the result of the research, the fraction of n-hexane, ethyl acetate fraction, and water fraction of kernel ethanol extract limus fruit seed have antibacterial activity against Staphylococcus aureus and Escherichia coli. The highest activity was shown by fraction of ethyl acetate with minimum killing concentration (KBM) to Staphylococcus aureus was 5% with diameter equal to 4,33 ± 1.17 mm equal to 30,27 μg / mL Tetracycline HCl, and KBM value to Escherichia coli.4% (7.60 ± 0.14) mm equivalent to 26, 04 μg / mL Tetracycline HCl. Keywords: Antibacterial, Staphylococcus aureus, Escherichia coli, Kernel, M. foetida.","PeriodicalId":16805,"journal":{"name":"Journal of Pharmacopolium","volume":"2003 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2018-09-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"82895890","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

ISOLASI ZAT WARNA BARU Monascus purpureus DARI HASIL FERMENTASI PADAT DENGAN BERAS SEBAGAI SUBSTRAT 从以大米为基质发酵的固体中分离出新色球菌

Journal of Pharmacopolium Pub Date : 2018-09-03 DOI: 10.36465/JOP.V1I1.391

A. Yuliana

{"title":"ISOLASI ZAT WARNA BARU Monascus purpureus DARI HASIL FERMENTASI PADAT DENGAN BERAS SEBAGAI SUBSTRAT","authors":"A. Yuliana","doi":"10.36465/JOP.V1I1.391","DOIUrl":"https://doi.org/10.36465/JOP.V1I1.391","url":null,"abstract":"Monascus purpureus is a mold capable of producing pigment as secondary metabolites. Pigments of Monascus purpureus isolated from rice fermented solid known as red yeast rice. This study was conducted toMonascus purpureus know the potential in generating new compounds of pigment produced by solid fermentation process with rice as a substrate. The results indicate insulation compounds and new compounds of pigment Monascus purpureus. Beginning with an analysis of Thin Layer Chromatography (TLC) using the mobile phase n-hexane and ethyl acetate (7:3) with a Rf value obtained was 0.71. Analysis with UV-Vis spectrophotometry against red yeast rice extract aims to determine the maximum wavelength. The results of the analysis of UV-Vis spectrophotometry obtained one peak an absorption at 0.255 with a wavelength of 486 nm which showed that the red pigment monascorubramin compounds in Monascus purpureus. Isolation of Monascus purpureus pigments by Preparative Thin Layer Chromatography (Preparative TLC) using the mobile phase n-hexane and ethyl acetate (7:3). Results isolation pigment Monascus purpureus form of a ribbon that can fluoresces atλ 365 nm UV light with a Rf value obtained was 0.73 were further identification of the molecular weights of compounds Monascus purpureus using HPLC instruments with detectors MS (Mass Spectrometer). The results of LC-MS analysis of a sample INACC-F01 showed a new compound which has a molecular weight of 357.41 and based on the literature that the same compounds with molecular weight is Monascopyridine C which is a derived compound from Monascus red pigment that is monascorubramin and rubropunctamin. Keywords:Monascus purpureus, pigment, angkak, Preparative TLC, LC-MS.","PeriodicalId":16805,"journal":{"name":"Journal of Pharmacopolium","volume":"18 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2018-09-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"84775764","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

ANALISIS CEMARAN LOGAM BERAT MERKURI DALAM KRIM PEMUTIH WAJAH YANGBEREDAR DIPASAR TRADISIONAL DENGAN METODE SPEKTROFOTOMETRI SERAPANATOM 这是一种利用六烯光谱学方法在传统市场上循环的汞重金属分析

Journal of Pharmacopolium Pub Date : 2018-09-03 DOI: 10.36465/jop.v1i1.395

Vinas Anggraeni

引用次数: 5

EVALUASI SEDIAAN EMULGEL ANTI JERAWAT TEA TREE (Melaleuca alternifolia) OIL DENGAN MENGGUNAKAN HPMC SEBAGAI GELLING AGENT

Journal of Pharmacopolium Pub Date : 2018-09-03 DOI: 10.36465/jop.v1i1.392

Lusi Nurdianti

{"title":"EVALUASI SEDIAAN EMULGEL ANTI JERAWAT TEA TREE (Melaleuca alternifolia) OIL DENGAN MENGGUNAKAN HPMC SEBAGAI GELLING AGENT","authors":"Lusi Nurdianti","doi":"10.36465/jop.v1i1.392","DOIUrl":"https://doi.org/10.36465/jop.v1i1.392","url":null,"abstract":"Tea tree (Melaleuca alternifolia) oil memiliki terpinen-4-ol yang berfungsi sebagai antibakteri dan anti jamur yang memiliki potensi efektivitas mengobati jerawat. Penelitian ini bertujuan untuk mengetahui formulasi pembuatan sediaan dan evaluasi sediaan emugel Tea tree (Melaleuca alternifolia) oil dengan menggunakan Hidroxy propyl methyl cellulose (HPMC) sebagai gelling agent.Untuk memperoleh sediaan emulgel yang memiliki stabilitas baik maka dilakukan serangkaian tahapan penelitian mulai dari pengumpulan bahan baku, formulasi dan evaluasi sediaan emulgel Tea tre oil. Formulasi yang dibuat terdiri dari tiga formula yaitu F1, F2 dan F3 dengan variasi HPMC sebagai gelling agent. Evaluasi yang dilakukan adalah uji organoleptik, pH, homogenitas, daya sebar, viskositas, Cycling test dan uji hedonik. Analisis data hasil uji viskositas dan uji hedonik diolah dengan penjabaran deskriptif. Hasil uji hedonik menunjukan bahwa emulgel anti jerawat tea tree oil dapat diterima oleh responden. Kata kunci : emulgel, Melaleuca alternifolia, HPMC","PeriodicalId":16805,"journal":{"name":"Journal of Pharmacopolium","volume":"83 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2018-09-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"87652304","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 10

UJI ANTIBAKTERI RIMPANG GANDASULI (HEDYCHIUM CORONARIUM) TERHADAP BAKTERI STAPHYLOCOCCUS AUREUS DAN ESCHERICHIA COLI DENGAN PERBANDINGAN METODE EKSTRAKSI 医用菌根根杆菌(HEDYCHIUM CORONARIUM)与菌根菌菌和ESCHERICHIA大肠杆菌进行比较

Journal of Pharmacopolium Pub Date : 2018-08-20 DOI: 10.36465/jop.v1i2.326

Aris Suhardiman

{"title":"UJI ANTIBAKTERI RIMPANG GANDASULI (HEDYCHIUM CORONARIUM) TERHADAP BAKTERI STAPHYLOCOCCUS AUREUS DAN ESCHERICHIA COLI DENGAN PERBANDINGAN METODE EKSTRAKSI","authors":"Aris Suhardiman","doi":"10.36465/jop.v1i2.326","DOIUrl":"https://doi.org/10.36465/jop.v1i2.326","url":null,"abstract":"Indonesia has various types of plants those have potential as medicine to overcome health problems in line with the expanding of traditional medicine industry. One example of plants from the Zingiberaceae family is Hedychium coronarium, which is not widely known by the community despite it has efficacy as an antibacterial which is not inferior to other Zingiberaceae family. The research was conducted to determine whether the Hedychium coronarium rhizome shown to have antibacterial activity against the growth of Staphylococcus aureus and Escherichia coli, knowing antibacterial compound that contained in Hedychium coronarium rhizome, also knowing the most effective extraction method to take the antibacterial compound from Hedychium coronarium rhizome. The gandasuli rhizome was extracted by maceration and reflux with 96% ethanol. Antibacterial activity test carried out by the agar diffusion method, and the analysis of antibacterial compounds with bioautography, and the results are monitored with vanillin-sulfuric acid. Maceration and reflux extract at a concentration of 90% has antibacterial activity with inhibition zones, each for 8 and 10 mm against Escherichia coli as well as 9 and 10 mm against Staphylococcus aureus. Bioautography results show a positive effect on the appearance of vanillin-sulfuric acid. Reflux extract has better antibacterial activity, while the antibacterial compound is an essential oil group. Keywords: Hedychium coronarium, antibacterial, Staphylococcus aureus, Escherichia coli, bioautography.","PeriodicalId":16805,"journal":{"name":"Journal of Pharmacopolium","volume":"19 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2018-08-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"73585187","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

CHARACTERIZATION AND SYNTHESIZE OF Fe(III) 4-FLUORO-N’-[(PYRIDINE-4-YL)CARBONYL]BENZOHYDRAZIDE COMPLEX AS ANTITUBERCULOSIS CANDIDATE 抗结核候选物铁(III) 4-氟- n′-[(吡啶-4-基)羰基]苯并肼配合物的表征与合成

Journal of Pharmacopolium Pub Date : 2018-08-20 DOI: 10.36465/JOP.V1I2.332

R. Ruswanto

引用次数: 2

GAMBARAN PELAYANAN FARMASI KLINIK DI APOTEK WILAYAH KOTA TANGERANG SELATAN CLINICAL PHARMACY SERVICE AT COMMUNITY PHARMACY IN SOUTH TANGERANG REGENCY

Journal of Pharmacopolium Pub Date : 2018-08-20 DOI: 10.36465/JOP.V1I2.329

Ahmad Apriansyah

{"title":"GAMBARAN PELAYANAN FARMASI KLINIK DI APOTEK WILAYAH KOTA TANGERANG SELATAN CLINICAL PHARMACY SERVICE AT COMMUNITY PHARMACY IN SOUTH TANGERANG REGENCY","authors":"Ahmad Apriansyah","doi":"10.36465/JOP.V1I2.329","DOIUrl":"https://doi.org/10.36465/JOP.V1I2.329","url":null,"abstract":"Background : Giving the drug information and counceling are parts of pharmacist clinical task as be stated in ministry of health statue number 35 year 2014 on Pharmacy service standar in community pharmacy (Permenkes no 35 tahun 2017 tentang standar pelayanan kefarmasian di apotek). Through these tasks, pharmacist can inprove the patient therapy outcome. Aim : The purpose o this study was to describe the clinical service of drug information in community pharmacies (CP) at South Tangerang City. Methods : This was a descriptive-explorative study with survey technic. Sample were the 50 CPs and clinical pharmacy services were evaluated on their pharmacist who could be met at the visiting time. Results & Conclusion : Thirty eight percent of pharmacists could be met at the visiting time. The highest percentage of drug information service is drug usage (72,22%) whereas the lowest are drug interaction and the way of its prevention i.e 5,55%. The quality of pharmacy clinical service of drug information is 41,66% and meet the bad criteria. The clinical pharmacy service of drug information in south Tangerang has not been run well and met the Pharmacy service standard yet. Keywords: drug information service, pharmacit, south tangerang, community pharmacy.","PeriodicalId":16805,"journal":{"name":"Journal of Pharmacopolium","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2018-08-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"90349367","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1