T. Lima‐Silva, T. Ordonez, Gabriela dos Santos, A. Moreira, C. Verga, G. Ishibashi, G. Silva, P. Prata, L. Moraes, S. Brucki
{"title":"Effects of working memory training on cognition in healthy older adults: A systematic review","authors":"T. Lima‐Silva, T. Ordonez, Gabriela dos Santos, A. Moreira, C. Verga, G. Ishibashi, G. Silva, P. Prata, L. Moraes, S. Brucki","doi":"10.1590/1980-5764-dn-2021-0119","DOIUrl":"https://doi.org/10.1590/1980-5764-dn-2021-0119","url":null,"abstract":"ABSTRACT. The working memory (WM) training in older adults can benefit their cognition. However, there is a dearth of literature reviews on the subject. Objective: This study aimed to investigate and evaluate the effects of WM training on the cognition of healthy older adults, in individual and group interventions reported in the literature. Methods: This is a systematic review involving a qualitative analysis of publications on the SciELO, LILACS, and MEDLINE databases carried out between March and June 2021. Results: A total of 47 studies were identified and analyzed, comprising 40 in older adults only and 7 comparing older and younger adults, investigating individual or group WM training or other types of intervention focused on WM effects. Conclusions: Both individual and group intervention contributed to the maintenance and/or improvement of cognition in older adults exploiting brain plasticity to promote mental health and prevent cognitive problems that can negatively impact quality of life of this group.","PeriodicalId":167803,"journal":{"name":"Dementia & Neuropsychologia","volume":"78 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"122933510","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Manuelle Mastrorocco Brand Rosa, Y. Fragoso, Ana Carolina Lemes Scaciota, Giuliana Raduan Crizol, M. Colovati, Eduardo Calmon de Moura, A. L. Martimbianco
{"title":"Evidence from Cochrane systematic reviews on pharmacological treatment compared to placebo for panic disorder","authors":"Manuelle Mastrorocco Brand Rosa, Y. Fragoso, Ana Carolina Lemes Scaciota, Giuliana Raduan Crizol, M. Colovati, Eduardo Calmon de Moura, A. L. Martimbianco","doi":"10.1590/1980-5764-dn-2022-0022","DOIUrl":"https://doi.org/10.1590/1980-5764-dn-2022-0022","url":null,"abstract":"ABSTRACT. Panic disorder is an anxiety condition characterized by recurrent and unexpected panic attacks. The comparison between active treatment and placebo is essential to analyze an intervention’s efficacy and safety. It is important to identify and summarize the studies with higher evidence to assist health professionals and public policy managers in clinical decision-making. Objective: The aim of this study was to identify and summarize all Cochrane systematic reviews (SRs) that compared the efficacy and safety of any drug treatment compared to placebo for panic disorder patients. Methods: SRs published in the Cochrane Library were included without date restriction. All outcomes presented were analyzed. The methodological quality of the SRs was evaluated using the AMSTAR-2 tool. Results: We included three Cochrane SRs of high methodological quality on the effects of antidepressants, benzodiazepines, and azapirones for panic disorder. All medications showed benefits in response to treatment, symptom improvement, and reduced panic attacks. Dropouts were lower with tricyclic antidepressants and benzodiazepines and higher with azapirones. The occurrence of adverse events was higher for drug groups. Conclusions: Very low to moderate certainty evidence (GRADE) showed that antidepressants and benzodiazepines seem to improve clinical symptoms in individuals with short-term panic disorder compared to placebo. In addition, the use of azapirones seems to have greater adherence by patients than placebo. However, there is insufficient evidence to support its clinical efficacy.","PeriodicalId":167803,"journal":{"name":"Dementia & Neuropsychologia","volume":"18 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"126552828","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Performance on the matrix reasoning by Parkinson’s disease patients: strategy is in the eye of the beholder","authors":"Y. Alamri","doi":"10.1590/1980-5764-dn-2022-0031","DOIUrl":"https://doi.org/10.1590/1980-5764-dn-2022-0031","url":null,"abstract":"","PeriodicalId":167803,"journal":{"name":"Dementia & Neuropsychologia","volume":"100 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-09-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"134087175","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Neuropsychological findings in migraine: a systematic review","authors":"Hanna Hakamäki, M. Jehkonen","doi":"10.1590/1980-5764-dn-2022-0004","DOIUrl":"https://doi.org/10.1590/1980-5764-dn-2022-0004","url":null,"abstract":"ABSTRACT. Patients with migraine often experience cognitive dysfunction during a migraine attack, but they have also been reported to complain about cognitive impairment after an attack and during the interictal period. Objective: The aim of this study was to determine what neuropsychological test methods are used to assess cognitive functioning in migraine patients and to examine the neuropsychological findings in adult (≥18 years) migraineurs compared to adult (≥18 years) healthy controls (HC). Methods: A systematic review was conducted on the literature published between 2012 and the present. The search results were screened and additional studies identified in the lists of references in the selected articles. A total of 16 articles met the inclusion criteria. Results: The 16 articles included in the review compared chronic migraineurs (CM), migraineurs with (MwA) and without aura (MwoA), and migraineurs without aura classification (MIG) to HC. A total of 45 neuropsychological assessment methods were identified. CM and MwA were found to perform significantly worse than HC in executive function, attention, and visual functioning. Additionally, both MwA and MwoA performed significantly worse than HC in memory functions. CM and both MwA and MwoA also performed significantly worse than HC in general cognitive functioning. Surprisingly, MIG performed significantly better than HC in several cognitive domains, including executive, motor, and language functioning and general cognitive functioning. Conclusions: This systematic review mostly concurs with the results of an earlier systematic review on the topic from 2012, but with the important addition that different migraine diagnostic groups should be assessed separately.","PeriodicalId":167803,"journal":{"name":"Dementia & Neuropsychologia","volume":"26 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-09-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"116436915","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Avoiding surgery in patients with dementia: is it the correct management?","authors":"Tomonari Koto, Yoji Kurihara, M. Shoji, K. Meguro","doi":"10.1590/1980-5764-dn-2021-0120","DOIUrl":"https://doi.org/10.1590/1980-5764-dn-2021-0120","url":null,"abstract":"ABSTRACT. Although hospitalization for dementia is increasing, Japanese doctors often refrain from surgeries considering dementia. A woman in her 80s diagnosed with Alzheimer’s disease was admitted to hospital for cholelithiasis. Due to the avoidance of surgery, the inflammation was prolonged and therefore she was unable to eat. Later, she was discharged with central venous nutrition. The care burden on family resulted in her readmission to another hospital. Eventually, the inflammation was alleviated, and she was able to eat. However, it took a long time. In this study, we not only emphasize the risks but also focus on the benefits to postoperative rehabilitation. We also discuss about the benefits of invasive procedures in patients with dementia.","PeriodicalId":167803,"journal":{"name":"Dementia & Neuropsychologia","volume":"23 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-09-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"126172986","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
P. Caramelli, V. Marinho, J. Laks, M. Coletta, F. Stella, E. Camargos, J. Smid, B. Barbosa, L. Schilling, M. Balthazar, N. Frota, L. Souza, F. Vale, M. Chaves, S. Brucki, R. Nitrini, H. Durgante, P. Bertolucci
{"title":"Treatment of dementia: recommendations of the Scientific Department of Cognitive Neurology and Aging of the Brazilian Academy of Neurology","authors":"P. Caramelli, V. Marinho, J. Laks, M. Coletta, F. Stella, E. Camargos, J. Smid, B. Barbosa, L. Schilling, M. Balthazar, N. Frota, L. Souza, F. Vale, M. Chaves, S. Brucki, R. Nitrini, H. Durgante, P. Bertolucci","doi":"10.1590/1980-5764-dn-2022-s106en","DOIUrl":"https://doi.org/10.1590/1980-5764-dn-2022-s106en","url":null,"abstract":"ABSTRACT There is currently no cure for neurodegenerative or vascular dementias, but some pharmacological and non-pharmacological interventions may contribute to alleviate symptoms, slow disease progression and improve quality of life. Current treatment approaches are based on etiology, symptom profile and stage of dementia. This manuscript presents recommendations on pharmacological and non-pharmacological treatments of dementia due to Alzheimer’s disease, vascular cognitive impairment, frontotemporal dementia, Parkinson’s disease dementia, and dementia with Lewy bodies.","PeriodicalId":167803,"journal":{"name":"Dementia & Neuropsychologia","volume":"18 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"131405002","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
L. Souza, M. L. Hosogi, T. Machado, M. T. Carthery-Goulart, M. Yassuda, J. Smid, B. Barbosa, L. Schilling, M. Balthazar, N. Frota, Francisco Assis Carvalho Vale, P. Caramelli, P. Bertolucci, M. Chaves, S. Brucki, R. Nitrini, V. Bahia, L. Takada
{"title":"Diagnosis of frontotemporal dementia: recommendations of the Scientific Department of Cognitive Neurology and Aging of the Brazilian Academy of Neurology","authors":"L. Souza, M. L. Hosogi, T. Machado, M. T. Carthery-Goulart, M. Yassuda, J. Smid, B. Barbosa, L. Schilling, M. Balthazar, N. Frota, Francisco Assis Carvalho Vale, P. Caramelli, P. Bertolucci, M. Chaves, S. Brucki, R. Nitrini, V. Bahia, L. Takada","doi":"10.1590/1980-5764-dn-2022-s103en","DOIUrl":"https://doi.org/10.1590/1980-5764-dn-2022-s103en","url":null,"abstract":"ABSTRACT “Frontotemporal dementia” (FTD) is a clinical syndrome characterized by the focal involvement of the frontal and/or temporal lobes. FTD has three clinical phenotypes: the behavioral variant and two linguistic subtypes, namely, non-fluent/agrammatic primary progressive aphasia (PPA-NF/A) and semantic PPA (PPA-S). FTD is the second most common cause of dementia in individuals under the age of 65 years. This article presents recommendations for the diagnosis of FTD in the Brazilian scenario, considering the three levels of complexity of the health system: primary health care, secondary and tertiary levels. Diagnostic guidelines are proposed, including cognitive testing, behavioral and language assessments, laboratory tests, and neuroimaging.","PeriodicalId":167803,"journal":{"name":"Dementia & Neuropsychologia","volume":"83 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"114920463","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
L. Schilling, M. Balthazar, Márcia Radanovic, O. Forlenza, M. Silagi, J. Smid, B. Barbosa, N. Frota, L. C. D. Souza, Francisco Assis Carvalho Vale, P. Caramelli, P. Bertolucci, Márcia Lorena Fagundes Chaves, S. Brucki, B. Damasceno, R. Nitrini
{"title":"Diagnosis of Alzheimer’s disease: recommendations of the Scientific Department of Cognitive Neurology and Aging of the Brazilian Academy of Neurology","authors":"L. Schilling, M. Balthazar, Márcia Radanovic, O. Forlenza, M. Silagi, J. Smid, B. Barbosa, N. Frota, L. C. D. Souza, Francisco Assis Carvalho Vale, P. Caramelli, P. Bertolucci, Márcia Lorena Fagundes Chaves, S. Brucki, B. Damasceno, R. Nitrini","doi":"10.1590/1980-5764-dn-2022-s102en","DOIUrl":"https://doi.org/10.1590/1980-5764-dn-2022-s102en","url":null,"abstract":"ABSTRACT This paper presents the consensus of the Scientific Department of Cognitive Neurology and Aging from the Brazilian Academy of Neurology on the diagnostic criteria for Alzheimer’s disease (AD) in Brazil. The authors conducted a literature review regarding clinical and research criteria for AD diagnosis and proposed protocols for use at primary, secondary, and tertiary care levels. Within this clinical scenario, the diagnostic criteria for typical and atypical AD are presented as well as clinical, cognitive, and functional assessment tools and complementary propaedeutics with laboratory and neuroimaging tests. The use of biomarkers is also discussed for both clinical diagnosis (in specific conditions) and research.","PeriodicalId":167803,"journal":{"name":"Dementia & Neuropsychologia","volume":"43 1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"126764579","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
S. Brucki, I. Aprahamian, W. Borelli, V. C. Silveira, Ceres Ferretti, J. Smid, B. Barbosa, L. Schilling, M. Balthazar, N. Frota, L. Souza, Francisco Assis Carvalho Vale, P. Caramelli, P. Bertolucci, M. Chaves, R. Nitrini, R. Schultz, L. Morillo
{"title":"Management in severe dementia: recommendations of the Scientific Department of Cognitive Neurology and Aging of the Brazilian Academy of Neurology","authors":"S. Brucki, I. Aprahamian, W. Borelli, V. C. Silveira, Ceres Ferretti, J. Smid, B. Barbosa, L. Schilling, M. Balthazar, N. Frota, L. Souza, Francisco Assis Carvalho Vale, P. Caramelli, P. Bertolucci, M. Chaves, R. Nitrini, R. Schultz, L. Morillo","doi":"10.1590/1980-5764-dn-2022-s107en","DOIUrl":"https://doi.org/10.1590/1980-5764-dn-2022-s107en","url":null,"abstract":"ABSTRACT Alzheimer’s disease (AD) and other neurodegenerative dementias have a progressive course, impairing cognition, functional capacity, and behavior. Most studies have focused on AD. Severe dementia is associated with increased age, higher morbidity-mortality, and rising costs of care. It is fundamental to recognize that severe dementia is the longest period of progression, with patients living for many years in this stage. It is the most heterogeneous phase in the process, with different abilities and life expectancies. This practice guideline focuses on severe dementia to improve management and care in this stage of dementia. As it is a long period in the continuum of dementia, clinical practice should consider non-pharmacological and pharmacological approaches. Multidisciplinary interventions (physical therapy, speech therapy, nutrition, nursing, and others) are essential, besides educational and support to caregivers.","PeriodicalId":167803,"journal":{"name":"Dementia & Neuropsychologia","volume":"55 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"124510227","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Physical inactivity and dementia in Brazil: a call to action","authors":"N. Feter, J. S. Leite","doi":"10.1590/1980-5764-dn-2022-0014","DOIUrl":"https://doi.org/10.1590/1980-5764-dn-2022-0014","url":null,"abstract":"ABSTRACT. Low- and middle-income countries will house two-thirds of cases of dementia in the world by 2050, while the incidence is decreasing in some high-income countries. In Brazil, one in four cases of dementia can be attributable to physical inactivity. Considering the projected prevalence of dementia by 2050 in Brazil, well-coordinated task forces are needed to improve awareness of non-pharmacological approaches in order to reduce the current and projected burden of dementia in the country. In this study, we discussed the current scenario and perspectives of physical inactivity and dementia in Brazil.","PeriodicalId":167803,"journal":{"name":"Dementia & Neuropsychologia","volume":"33 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-08-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"123984297","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}