Journal of National Institute of Neurosciences Bangladesh最新文献

{"title":"Relationship of Glycemic Status with Disease Severity in Guillain-Barré Syndrome","authors":"Mohammad A. Hossain, M. Hasan, M. Rahman, M. Baqui, Mahmudul Islam, M. Hakim","doi":"10.3329/jninb.v6i2.50762","DOIUrl":"https://doi.org/10.3329/jninb.v6i2.50762","url":null,"abstract":"Background: Guillain-Barré syndrome (GBS) is an acute autoimmune polyneuroradiculopathy characterized by flaccid paralysis which may lead to respiratory failure requiring intensive care. \u0000Objective: The purpose of the present study was to explore the relationship between the fasting plasma glucose (FPG), hemoglobin A1c (HbA1c) and disease severity of GBS patients who are not known to have DM. \u0000Methodology: This cross-sectional study included adult GBS patients without having DM [age 35 (22-48) years, median (interqurtile range, IQR); 39 male 22 female] who were admitted to Neurology department, National Institute of Neurosciences and Hospital, Dhaka, Bangladesh from July 2018 to June 2019. Demographics, clinical data were noted and FPG, HbA1c were measured. Disease severity were assessed by the GBS disability scale ranging from 0 to 6 with increasing score reflecting increased disability. \u0000Results: Patients with more severe GBS (disability score ≥4, unable to walk) had higher frequency of elevated FPG >5.5 mmol/L (61.2%; 30/49) in comparison to those with less severe GBS (disability score ≤3, able to walk; FPG >5.5 mmol/L in 16.7%, 2/12; p=0.006). But distribution of HbA1c category was not different across the groups (disability score ≥4 vs. ≤3: HbA1c <5.7: 40% vs. 58%; 5.7-6.4: 50% vs. 25%; >6.4: 10% vs. 17%; p=0.296). Participants with elevated FPG were elder [elevated vs. normal FPG: 40 (28-54) vs. 25 (19-43) years; median (IQR), p=0.012] and had higher CSF glucose (p=0.002) than those with normal FPG, but there was no difference in respct of gender, MRC sum score, requirement of assisted ventilation, CSF protein, GBS subtypes and duration of hospital stay (p=not significant for all). \u0000Conclusions: Patients with severe GBS have higher frequency of elevated FPG but not HbA1c. An acute change in glucose metabolism may occur in GBS which needs further study. \u0000Journal of National Institute of Neurosciences Bangladesh, 2020;6(2): 96-100","PeriodicalId":16732,"journal":{"name":"Journal of National Institute of Neurosciences Bangladesh","volume":"55 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2020-12-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"75501806","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Covid-19 Infection Complicated with Aortic Thrombosis: A Case Report","authors":"Zakirul Islam, A. Ara, K. Fatema, R. Anne, Mostafizur Rahman, M. E. Hussain, Abdul M Yusuf","doi":"10.3329/jninb.v6i2.50783","DOIUrl":"https://doi.org/10.3329/jninb.v6i2.50783","url":null,"abstract":"Thromboembolic complications are well recognized events in Covid-19 infection. Most of the case fatalities are due to this event. Although any blood vessels may be involved, larger vessels are less commonly involved in this process. Here we describe a case of thrombosis of the arch of the aorta in association of Covid-19 infection in a hospitalized patient. The aim was to ensure timely identification and therapeutic intervention to prevent distal thromboembolic sequelae. \u0000Journal of National Institute of Neurosciences Bangladesh, 2020;6(2): 143-145","PeriodicalId":16732,"journal":{"name":"Journal of National Institute of Neurosciences Bangladesh","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2020-12-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"80843500","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Factors Associated with Hypertension among Urban Dwellers with Sedentary Lifestyle: A Cross-Sectional Study","authors":"A. I. Joardar, F. I. Khaled, S. Mahabub, C. Singha, M. A. Haque","doi":"10.3329/jninb.v6i2.50780","DOIUrl":"https://doi.org/10.3329/jninb.v6i2.50780","url":null,"abstract":"Background: Hypertension is a serious public health problem and an important research area due to its worldwide high prevalence and being a prime risk factor for cardiovascular diseases and other complications. In developing countries, hypertension is more prevalent among the urban population who lead a sedentary lifestyle. \u0000Objective:This study aimed to investigate the prevalence and risk factors of hypertension among urban dwellers with sedentary life. \u0000Methodology: This cross-sectional study was conducted among the adult population (18 years and above) living in one of the urban areas of Dhaka (Dania Union, Kadamtali Thana), Bangladesh. The study was conducted from January 2018 to October 2018, using a simple random sampling technique for data collection. The adult respondents were enrolled in this study who were staying at home and leading a sedentary lifestyle. Univariate analysis and binary logistic regression analysis were performed to examine the risk factors of hypertension of the study population. \u0000Results: A total of 149 adults were enrolled in this study. The mean (±SD) age of the study population was 51.20 (±14.65) years. About four out of 10 study population were found to be hypertensive in this study. The adjusted logistic regression analysis revealed that increased age groups, i.e., 50 to 60 years old [AOR: 3.11, 95% CI: 1.01 – 9.66] and 60 years old and above [AOR: 5.83, 95% CI: 1.73 – 20.06], and family history of hypertension (AOR: 3.59, 95% CI: 1.34 - 9.63) had a positive and significant association with hypertension. However, people with high socioeconomic status showed 71 percent less likelihood of being hypertensive than the lower ones. \u0000Conclusion: The prevalence of hypertension among the people leading a sedentary lifestyle was significantly higher in this study. Increasing physical activity, maintaining proper antihypertensive medication, and regular follow-up of hypertension for older adults might inhibit the increased prevalence of hypertension in urban areas. \u0000Journal of National Institute of Neurosciences Bangladesh, 2020;6(2): 129-134","PeriodicalId":16732,"journal":{"name":"Journal of National Institute of Neurosciences Bangladesh","volume":"14 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2020-12-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"73588720","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Ability of Extracts of Spirulina for the Removal of Arsenic from Isolated Liver Tissues of Experimental Rat","authors":"Andalib Mustafa Iqbal Ira, S. Jesmin, S. Akhter, Mahfuza Mazeda Rowshan, E. O. Eva, M. Misbahuddin","doi":"10.3329/jninb.v6i2.50764","DOIUrl":"https://doi.org/10.3329/jninb.v6i2.50764","url":null,"abstract":"Background: Spirulina has several effects in the metabolism of the body. \u0000Objective: The purpose of the present study was to see the ability of extracts of spirulina for the removal of arsenic from isolated liver tissues of rat. \u0000Methodology: This animal study was carried out on isolated liver tissues of Long Evans Norwegian adult healthy male rats weighing 160 to 200 g. The rats were 3 to 6 months of age obtained from animal house of Bangabandhu Sheikh Mujib Medical University, Dhaka, Bangladesh from 2004 to 2005. Measurements and all tasks were performed in a very careful manner. Atomic Absorption Spectrophotometer with Hydride Generator was used to measure the arsenic level. A set of freshly washed test tubes was taken. All test tubes contained 2ml tyrode solution and twenty small pieces of liver tissue maintaining 00C. No arsenic was added in test tube I. 2.5 μg/ml arsenic trioxide was added rest of the test tubes. They all were incubated for 45 minutes at 370C. Then the tissues were washed properly. The extracts of spirulina was added at 20 μl/ml dose. Second incubation was also for another 45 minutes at 370C. There were duplicates of all test tubes. \u0000Result: The effects of different extracts of spirulina (E1, E2, E4 and E7) on the removal of arsenic from arsenic loaded tissue were recorded. Amount of accumulated arsenic (mean ± se) in blank was 6.04 ± 3.05 μg/g of protein. After administration of 2.5 μg/ml arsenic trioxide in both incubation, the amount of accumulated arsenic was 245.02 ± 22.37 μg/g of protein. Blank was deducted from the standard and the value was considered as control and it was 238.96 ± 19.32 μg / g of protein. The arsenic loaded tissues were incubated with different extracts (E1, E2, E4 and E7) of spirulina in second incubation for another 45 minutes at 370C and each extract was for 20 μl / ml. After E1 extract of spirulina in second incubation, amount of accumulated arsenic was 136.40 ± 14.23 μg / g. There was 14.81% of removal of arsenic. Second incubation with E2 extract of spirulina (20 μl/ml) on arsenic loaded (2.5 μg/ml) tissue showed the amount of arsenic 242.56 ± 16.50 μg/g of protein (mean ± se). There was 12.59% of removal of arsenic. \u0000Conclusion: In conclusion extracts of spirulina has a significant ability to remove arsenic from isolated liver tissues of experimental rat. \u0000Journal of National Institute of Neurosciences Bangladesh, 2020;6(2): 105-109","PeriodicalId":16732,"journal":{"name":"Journal of National Institute of Neurosciences Bangladesh","volume":"9 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2020-12-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"85617231","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Demographic Profiles of Animal Bite Cases at a Dedicated Anti-Rabies Hospital in Dhaka City of Bangladesh","authors":"A. Yusuf, Tanzina Jahan, A. Sattar, S. Shahid, N. Sultana, A. Shamsuzzaman","doi":"10.3329/jninb.v6i2.50781","DOIUrl":"https://doi.org/10.3329/jninb.v6i2.50781","url":null,"abstract":"Background: Animal bite management are very crucial part in the post prophylaxis treatment. \u0000Objective: The purpose of the present study was to see the demographic profile of animal bite cases at a dedicated anti-rabies hospital. \u0000Methodology: This retrospective chart review based on secondary data received from animal bite register was conducted in the Department of Microbiology at National Institute of Neurosciences & Hospital, Dhaka, Bangladesh from January 2014 to December 2015 for a period of two years. All relevant data were noted from the registered record. \u0000Result: A total number of 17688 cases were collected from the register log book of animal bite. The mean age with standard deviation was 24.42±17.22 with the range of 1 to 99 years. The ratio between male and female was 2.33:1. The most common animal bite was dog bite which was 13574(76.7%) cases followed by cat, monkey, fox and weasel bite which were 3667(20.7%) cases, 163(0.9%) cases, 39(0.2%) cases and 22(0.1%) cases respectively. Lower extremity was the most site of bite by the animals which was 12936(73.1%) cases followed by upper extremity, waist, head & neck, face and trunk which were 3592(20.3%) cases, 428(2.4%) cases, 155(0.9%) cases, 116(0.7%) and 114(0.6%) cases respectively. The most common category of bite was category II which was 11800(66.7%) cases. \u0000Conclusion: In conclusion male young adult person bite by dog with category II are the most common victims of animal bites seeking for treatment. \u0000Journal of National Institute of Neurosciences Bangladesh, 2020;6(2): 135-139","PeriodicalId":16732,"journal":{"name":"Journal of National Institute of Neurosciences Bangladesh","volume":"59 4 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2020-12-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"78553151","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Histopathological Pattern and Different Stages of Sinonasal Carcinoma Patients: A Study on 40 Cases in Bangladesh","authors":"M. Haque, A. Biswas, A. Ahsan, Idrish Ali, Harun Ar Rashid Talukdar, M. A. Chowdhury","doi":"10.3329/jninb.v6i2.50765","DOIUrl":"https://doi.org/10.3329/jninb.v6i2.50765","url":null,"abstract":"Background: Sino-nasal carcinoma has various histological types presented with different stages. \u0000Objectives: The purpose of this present study was to see the histopathological types and stages of sinonasal carcinoma patients in tertiary level hospital. \u0000Methodology: This cross-sectional study was conducted in the Department of Otolaryngology- Head & Neck Surgery at Bangabandhu Sheikh Mujib Medical University, Dhaka, Bangladesh and Dhaka Medical College Hospital, Dhaka, Bangladesh from January 2008 to December 2009 for a period of two (02) years.All consecutive cases of sinonasal carcinoma admitted in hospital and outpatient department during the study period. Suspected cases of sinonasal carcinoma was diagnosed from history and clinical examination proved by CT-scan, MRI and histopathological examination. \u0000Result: A total number of 40 cases of sino-nasal carcinoma were recruited for this study. Among these single site involvement was reported in 11 cases and the rest 29 cases were involved in multiple sites. Regarding multiple sites involvement maxillary sinus with nasal cavity involvement was reported in 15(51.72%) cases. Maxillary sinus, nasal cavity with ethmoid sinus involvement was found in 10(34.48%) cases. The presentation of the sinonasal carcinoma at stage T4 was 16(40.05) cases followed by T3, T2, and T1 which were 13(32.5%) cases, 7(17.5%) cases and 4(10.0%) cases respectively. Squamous cell carcinoma was found in 25(63%) cases followed by adenocarcinoma andadenoid cyst carcinoma which were 7 cases, 5 cases respectively. \u0000Conclusion: In conclusion majority of the sino-nasal carcinoma are squamous cell carcinoma involving the multiple sites in the T4 stage. \u0000Journal of National Institute of Neurosciences Bangladesh, 2020;6(2): 110-113","PeriodicalId":16732,"journal":{"name":"Journal of National Institute of Neurosciences Bangladesh","volume":"38 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2020-12-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"78820567","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Prevalence of Extended Spectrum ß-Lactamase Producing Klebsiella Pneumoniae Isolates in A Tertiary Care Hospital in Bangladesh","authors":"S. J. Sonia, T. Ahsan, T. Ahmed, S. Nazneen, K. H. Uddin, S. Shamsuzzaman","doi":"10.3329/jninb.v6i2.50763","DOIUrl":"https://doi.org/10.3329/jninb.v6i2.50763","url":null,"abstract":"Background: Extended-spectrum β lactamases (ESBLs) continue to be a major challenge in clinical setups world over, conferring resistance to the expanded-spectrum cephalosporins. \u0000Objectives: The aim of this study was to determine the prevalence of extended spectrum β-lactamase (ESBL) in strains of Klebsiella pneumoniae isolated from different clinical specimens in Dhaka Medical College Hospital, Dhaka, Bangladesh. \u0000Methodology: This cross sectional study was carried out at the Department of Microbiology of Dhaka Medical College, Dhaka, Bangladesh from July 2016 to June 2017. Klebsiella pneumoniae were isolated from different clinical specimens from adult hospitalized patients. These isolates were screened for ESBL production according to Clinical and Laboratory Standards Institute (CLSI) guidelines. ESBL production was confirmed by the phenotypic confirmatory double disc synergy test (DDST). \u0000Results: Among the 500 collected samples 75 Klebsiella pneumoniae were isolated. Among them, 68 isolates were selected for confirmatory tests of ESBL according to CLSI guidelines. Finally, 19 isolates were confirmed as ESBL producers by DDST (25.33%). \u0000Conclusion: In the present study, a large number of isolates are found to be ESBL producers. \u0000Journal of National Institute of Neurosciences Bangladesh, 2020;6(2): 101-104","PeriodicalId":16732,"journal":{"name":"Journal of National Institute of Neurosciences Bangladesh","volume":"79 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2020-12-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"81357465","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Computed Tomography Angiography (CTA) Evaluation of Spontaneous Subarachnoid Hemorrhage","authors":"T. I. Chowdhury, Mohammad Shah Jahirul Hoque Chowdhury, Mohammad Sadekur Rahman Sarkar, K. Ahmed, Nazmul Kabir, Mohammad Rezaul Haque, Fahmida Rouf, T. Haider, N. Islam, K. Patwary, M. Shahi, B. Alam","doi":"10.3329/jninb.v6i2.50745","DOIUrl":"https://doi.org/10.3329/jninb.v6i2.50745","url":null,"abstract":"Background: In evaluation of non-traumatic subarachnoid hemorrhage CT angiography (CTA) has 97-98% sensitivity and near 100% specificity. \u0000Objective: This study was conducted to evaluate the CTA findings of CT positive non traumatic subarachnoid hemorrhage. \u0000Methodology: This is an observational cross sectional study performed in Neurology department of National Institute of Neurosciences and Hospital, Dhaka over one year period (January 2019 to December 2019). Total 87 CT positive subarachnoid hemorrhage cases were purposively included in this study. All CT positive patients underwent CTA of Cerebral vessels for further evaluation. The angiography were evaluated by competent neuro-radiologists blinded about the study. \u0000Result: Among 87 patients, 40.2% were male and 59.8% were female. The average age was 53.33±11.1 years. Among the studied patient the source of bleeding was found 78.16% aneurysmal and 21.84% non-aneurysmal. 85.30% patients had single aneurysm and 14.70% had multiple aneurysm. The highest number of patient had Acom aneurysm (41.17%) followed by MCA (22.05%), ICA (13.23%), ACA (7.35%) and vertebral artery (1.14%) in order of frequency. Among the multiple aneurysm group most of the patients had combination of Acom, MCA and ICA aneurysm. \u0000Conclusion: From this study, we can conclude that CTA can be used as the primary diagnostic tool in evaluation of spontaneous SAH. \u0000Journal of National Institute of Neurosciences Bangladesh, 2020;6(2): 78-81","PeriodicalId":16732,"journal":{"name":"Journal of National Institute of Neurosciences Bangladesh","volume":"77 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2020-12-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"85733230","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Brief Overview and Experience of Visual Evoked Potential of First 67 cases at Referral Neuroscience Hospital in Bangladesh","authors":"M. E. Hussain, B. Debnath, Afm Al Masum Khan, Ferdous Mian, N. Islam, B. Alam, Q. Mohammad, R. Chowdhury","doi":"10.3329/jninb.v6i2.50744","DOIUrl":"https://doi.org/10.3329/jninb.v6i2.50744","url":null,"abstract":"Background: The visual evoked potentials (VEP) is a valuable tool to document occult lesions of the central visual channels especially within the optic nerve. \u0000Objectives: The purpose of the present study was to observe the findings of first few cases of VEP done in the neurophysiology department of the National Institute of Neurosciences (NINS), Dhaka, Bangladesh. \u0000Methodology: This cross-sectional study was conducted in the Department of Neurophysiology at the National Institute of Neurosciences and Hospital, Dhaka, Bangladesh from September 2017 to March 2020. All patients referred to the Neurophysiology Department of NINS for VEP were included. Pattern reversal VEPs were done using standard protocol set by International Federation of Clinical Neurophysiology (IFCN). \u0000Results: The mean age of the study population was 30.70 (±12.11) years (6-68 years) with 31 (46.3%) male and 36 (53.7%) female patients. The mean duration of illness was 8.71 (±1.78) months (3 days- 120 months). Most common presenting symptom was blurring of vision (37.3%) and dimness of vision (32.8%). Patterned VEP revealed mixed type (both demyelinating and axonal) of abnormality in most cases [29(43.35)]. The most common clinical diagnosis was multiple sclerosis (29.85%) and optic neuropathy (26.87%). In the clinically suspected cases of multiple sclerosis, optic neuropathy and optic neuritis most of the cases of VEP were abnormal and the p value is 0.04 in optic neuropathy and optic neuritis. \u0000Conclusion: The commonest presentation of the patients in this series were blurring of vision and dimness of vision. The most common clinical diagnosis for which VEP was asked for, was optic neuritis and multiple sclerosis. Most abnormalities were of mixed pattern (demyelinating and axonal). \u0000Journal of National Institute of Neurosciences Bangladesh, 2020;6(2): 74-77","PeriodicalId":16732,"journal":{"name":"Journal of National Institute of Neurosciences Bangladesh","volume":"23 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2020-12-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"86514949","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Pattern of Stroke among Adult (A-MMD) and Childhood Onset (C-MMD) Moyamoya Disease","authors":"A. Hasan, K. Rahman, Sharif Uddin Khan, S. H. Hakim, M. Habib, B. Alam, Q. Mohammad","doi":"10.3329/jninb.v6i2.50747","DOIUrl":"https://doi.org/10.3329/jninb.v6i2.50747","url":null,"abstract":"Background: Though relatively rare, moyamoya disease (MMD) may have varied presentation in different age group. Different stroke types are major presentation of this enigmatic disease. Objective: The aim of this study was to compare the stroke subtypes among adult (A-MMD) and childhood onset (C-MMD) patients with Moyamoya disease (MMD). \u0000Methodology: This was a hospital based observational study, conducted in the department of Neurology, Dhaka Medical College Hospital, Bangabandhu Sheikh Mujib Medical University and National Institute of Neurosciences and Hospital, Dhaka, Bangladesh in between July, 2007 to June, 2016. Sample size included 36 children and 14 adult patients of MMD presenting with either ischemic or hemorrhagic stroke, within one month of the index event. \u0000Result: Majority of participants were below 10 years of age with a mean age at onset of 16.56(±10.6) years. There was a female predominance. Patients younger than 20 years, presented mostly with ischemic stroke (32 versus 4 patients); whereas those above 20 years of age presented mostly with hemorrhagic stroke (6 versus 8 patients). The difference was statistically significant (p value = 0.006). Large artery infarct (15) and hemodynamic infarct (17) were common among patients in children; whereas intracerebral hemorrhage (dICH, lICH, IVH among 3, 4 and 1 patients respectively) was frequent (8) among the adult (p value = 0.006). \u0000Conclusion: While different pattern of ischemic stroke is common among children with MMD, the adults present mostly with hemorrhagic stroke subtypes. \u0000Journal of National Institute of Neurosciences Bangladesh, 2020;6(2): 87-90","PeriodicalId":16732,"journal":{"name":"Journal of National Institute of Neurosciences Bangladesh","volume":"49 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2020-12-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"80760940","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}