Journal of Patient-Centered Research and Reviews最新文献

{"title":"Patient Information Needs During Ambulatory Medication Changes: A Qualitative Study.","authors":"Elaine Giletta, Vanessa B Hurley, Yushi Yang, Jessica L Schwartz, Rabia Jalalzai, Nicole L Mollenkopf, Raquel Mayne, Samantha I Pitts","doi":"10.17294/2330-0698.2129","DOIUrl":"10.17294/2330-0698.2129","url":null,"abstract":"<p><strong>Purpose: </strong>We performed interviews with patients and caregivers to explore whole-person, whole-regimen information needs at times of routine outpatient medication changes. We categorized information needs in this relatively unstudied context and identified which needs were commonly recognized as insufficiently met.</p><p><strong>Methods: </strong>We explored the content of the semi-structured interviews, which involved nine patients and two caregivers of pediatric patients, all of whom experienced a recent medication change in the outpatient setting of a large urban academic healthcare system. We used inductive thematic analysis to organize information needs into categories to identify key information gaps.</p><p><strong>Results: </strong>We identified five categories of patient information needs: (1) medication self-administration, (2) clinical reasoning informing the medication change, (3) pre-medication change expectations, (4) post-medication change behaviors, and (5) patient role and responsibilities in safe medication management. Through these categories, we highlighted five themes from which participants frequently described receiving insufficient information: (1) medication history, (2) anticipatory guidance about possible adverse effects, (3) self-monitoring and self-managing instructions, (4) safe information seeking, and (5) safe disposal of surplus medications.</p><p><strong>Conclusions: </strong>Our findings illustrate patient information needs at times of ambulatory medication changes and identify vulnerabilities where these needs may be insufficiently met. Providing tailored information at times of ambulatory medication changes might support patient engagement with medication safety practices and ultimately reduce patient harm associated with adverse medication events. Further research is needed to confirm these gaps in larger studies and examine this question within special populations, including pediatric caregivers and patients with limited English proficiency.</p>","PeriodicalId":16724,"journal":{"name":"Journal of Patient-Centered Research and Reviews","volume":"12 3","pages":"113-123"},"PeriodicalIF":1.6,"publicationDate":"2025-07-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12279303/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144690584","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Mechanisms and Intermediate Outcomes of a Community Translation to Adapt a Whole Family-Inclusive Lifestyle Intervention: A Pilot Evaluation.","authors":"Megan J Moran, Kimberly Padilla, Abby Neiser, Nicole Clark, Virginia Jimenez, Natalia Sanchez, Talia Thompson, Ana M Gutierrez-Colina, Jesse Owen, Chesleigh Keene, Matthew A Haemer, Lauren B Shomaker","doi":"10.17294/2330-0698.2135","DOIUrl":"10.17294/2330-0698.2135","url":null,"abstract":"<p><strong>Purpose: </strong>Involving community members in the process of translating scientific evidence into health messaging and interventions can lead to improved health outcomes and more patient-centered healthcare. Community Translation (CT) is one methodology for fostering collaboration between researchers and community members, and it has been shown to result in locally relevant, acceptable solutions to health challenges. There has been very little research on the direct effects that participation may have on community members who become involved in CT. Understanding the mechanisms of CT and its outcomes on participating community members is essential to maximizing the potential of CT. To address this gap, the present study explores processes theorized to be important to the effectiveness of CT.</p><p><strong>Methods: </strong>Utilizing self-report survey and brief open response data from community partners (N=8) involved in a CT to adapt a family-inclusive lifestyle intervention in the rural Mountain West, we sought to describe change in theorized mechanisms - knowledge, attitudes, and partnership dynamics - and intermediate effectiveness outcomes.</p><p><strong>Results: </strong>The results indicate that perceived knowledge, attitudes, partnership dynamics, and intermediate effectiveness outcomes all tended to increase across the CT, with intermediate effectiveness outcomes such as group impact, perceived benefits, belonging, and cultural relevance showing the largest changes.</p><p><strong>Conclusions: </strong>The findings provide preliminary support for the logic model and theoretical basis outlined by the developers of CT, as well as insights for ways to optimize this powerful community-based participatory research methodology.</p>","PeriodicalId":16724,"journal":{"name":"Journal of Patient-Centered Research and Reviews","volume":"12 3","pages":"124-133"},"PeriodicalIF":1.6,"publicationDate":"2025-07-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12279307/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144690583","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Abstracts From the 2025 Health Care Systems Research Network (HCSRN) Annual Conference, St. Louis, Missouri.","authors":"","doi":"10.17294/2330-0698.2220","DOIUrl":"https://doi.org/10.17294/2330-0698.2220","url":null,"abstract":"<p><p>The Health Care Systems Research Network (HCSRN) comprises 19 learning health systems with integrated care delivery and embedded research units. The network's annual conference serves as a forum for research teams from member institutions to disseminate project findings, explore scientific collaborations, and share insights about population-based research practices that can measurably improve health and health care for all. The theme of this year's conference was \"Optimizing Collaborations to Advance Health in a Dynamic Research Landscape.\" Abstracts presented at HCSRN 2025 are published in this issue supplement of the <i>Journal of Patient-Centered Research and Reviews</i>, the journal of record for HCSRN's annual conference proceedings.</p>","PeriodicalId":16724,"journal":{"name":"Journal of Patient-Centered Research and Reviews","volume":"12 3","pages":"148-203"},"PeriodicalIF":1.6,"publicationDate":"2025-07-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12279304/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144690581","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Comparative Efficacy and Safety of Cryoballoon vs Laser Balloon Ablation for Pulmonary Vein Isolation in Patients With Paroxysmal Atrial Fibrillation.","authors":"Mahmoud Ali, Dorota Magdon, Abdulghani Mounir, Lynn Erickson, James Adefisoye, Jim Kanani, Andy Kieu, Abdullah Malik, Ali Ali, Nour Ghosoun, Jodi Zilinski, Arshad Jahangir, M Eyman Mortada, Imran Niazi, Atul Bhatia","doi":"10.17294/2330-0698.2126","DOIUrl":"10.17294/2330-0698.2126","url":null,"abstract":"<p><strong>Purpose: </strong>Atrial fibrillation (AF), the most common arrhythmia in older adults, is often treated with cryoballoon ablation (CBA) or laser balloon ablation (LBA) when refractory to medication. We used real-world patient data to investigate differences in arrhythmia-free survival, procedure and fluoroscopy times, and complications between these techniques.</p><p><strong>Methods: </strong>In this single-center, retrospective study of 178 patients with symptomatic paroxysmal AF referred for first-time pulmonary vein isolation (PVI), 103 underwent CBA, and 75 underwent LBA. Recurrence was defined as any atrial arrhythmia of >30 seconds' duration after a three-month blanking period. Complications at 30 days were recorded. Kaplan-Meier analysis was used to estimate arrhythmia-free survival at one year for both groups. Categorical variables were expressed as n (%) and continuous variables as mean±standard deviation or median (Q1, Q3).</p><p><strong>Results: </strong>Baseline characteristics were similar between groups, with exception to left atrial volume index (CBA 32.2±10.9 ml/m²; LBA 36.0±11.0 ml/m², p=0.047). History of stroke was higher in CBA (13.6% vs 2.7%; p=0.012), as was coronary artery disease (35.0% vs 14.7%, p=0.002). Median fluoroscopy and procedure times (min) were significantly shorter in LBA (24.2 vs 31.6, p=0.004; 141.0 vs 210.0, p<0.0001, respectively). One-year arrhythmia-free survival rates were similar (CBA 79.1% vs LBA 78.7%, p=0.934), as were total complication rates (21.4% vs 16.0%, p=0.289), including rates of transient ischemic attack/stroke and vascular complications.</p><p><strong>Conclusions: </strong>In patients with paroxysmal AF undergoing PVI, CBA and LBA were equally efficacious at one year and demonstrated acceptably low complication rates. LBA was associated with reduced procedure time and fluoroscopy exposure.</p>","PeriodicalId":16724,"journal":{"name":"Journal of Patient-Centered Research and Reviews","volume":"12 3","pages":"106-112"},"PeriodicalIF":1.6,"publicationDate":"2025-07-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12279309/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144690582","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The Effects of a Mindfulness-Based Intervention on Depression and Anxiety in the Long-COVID Population.","authors":"Rachel Welbel, Elizabeth Rutha, Jeffrey Ording, Douglas Wang, Jana Hirschtick","doi":"10.17294/2330-0698.2128","DOIUrl":"10.17294/2330-0698.2128","url":null,"abstract":"<p><p>Long-COVID is a complicated, post-viral syndrome involving multiple body systems and can present with neuropsychiatric symptoms. Little has been reported about the neuropsychiatric symptoms of long-COVID, and validated treatments do not yet exist. There is prior evidence that mindfulness-based strategies have been helpful for those with chronic illnesses; shown significant decreases in anxiety, stress, and depression; and enhanced quality of life. In this study, we report on the utility of a mindfulness-based intervention on levels of anxiety and depression in a long-COVID population. Our hospital system founded both a \"Covid Recovery Clinic\" (CRC) and a \"Post-COVID Resilience Program\" (PCRP). The PCRP consisted of a six-week virtual group therapy protocol that focused on mindfulness-based practices. Before and after the therapy intervention, participants answered questionnaires to capture depressive and anxiety symptoms. Pre- and post-questionnaire scores do not show a significant improvement in depressive or anxiety symptoms, although the study was limited by a small sample size. Further research is needed to investigate whether similar programs with a larger sample size can improve the mental health status of patients suffering from long-COVID.</p>","PeriodicalId":16724,"journal":{"name":"Journal of Patient-Centered Research and Reviews","volume":"12 3","pages":"134-139"},"PeriodicalIF":1.6,"publicationDate":"2025-07-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12279302/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144690585","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The Hazard Ratio Is Equivalent to an Odds Under the Assumption of Proportional Hazards.","authors":"David M Thompson","doi":"10.17294/2330-0698.2156","DOIUrl":"10.17294/2330-0698.2156","url":null,"abstract":"<p><p>Clinicians routinely interpret statistical findings from medical research to inform patients of treatment benefits. Studies that use the hazard ratio present special challenges. Clinicians should not equate hazard ratios with risk ratios, ie, relative risks. However, clinicians can provide patients with a straightforward interpretation of the hazard ratio as an odds, as long as the ratio was calculated in a study in which the assumption of proportional hazards is justified. In such a case, the hazard ratio is equivalent to the odds that a person, who is randomly chosen from the group represented in the ratio's numerator, experiences an event before a randomly chosen person from the group represented in the ratio's denominator. A mathematical derivation for the equivalence is provided to further clarify this idea for clinicians.</p>","PeriodicalId":16724,"journal":{"name":"Journal of Patient-Centered Research and Reviews","volume":"12 3","pages":"140-143"},"PeriodicalIF":1.6,"publicationDate":"2025-07-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12279308/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144690586","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Transforming Health Care Through Research: Highlights From the 2025 Annual Conference of the Health Care Systems Research Network.","authors":"Michael A Horberg, Suzanne Simons","doi":"10.17294/2330-0698.2219","DOIUrl":"10.17294/2330-0698.2219","url":null,"abstract":"<p><p>During this unprecedented time of uncertainty and disruption, the 2025 Annual Conference of the Health Care Systems Research Network (HCSRN) took place on April 8 to 10, 2025, in St. Louis, Missouri, at the Marriott St. Louis Grand. Nearly 265 participants from 19 HCSRN member institutions came together to network, collaborate, and connect at the conference, which featured the theme, \"Optimizing Collaborations to Advance Health in a Dynamic Research Landscape.\"</p>","PeriodicalId":16724,"journal":{"name":"Journal of Patient-Centered Research and Reviews","volume":"12 3","pages":"144-147"},"PeriodicalIF":1.6,"publicationDate":"2025-07-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12279301/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144690587","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Bridging the Gap Between Knowledge and Practices Pertaining to Naloxone Use: A Single-Institution Experience in North Carolina.","authors":"Michael S Argenyi, Gisele Bailey, Christopher J McLouth, Erin Barnes, Candice J McNeil","doi":"10.17294/2330-0698.2103","DOIUrl":"https://doi.org/10.17294/2330-0698.2103","url":null,"abstract":"<p><p>Naloxone is a life-saving medication for opioid overdose, which claims many lives annually. This study investigated provider attitudes about, beliefs about, and barriers to naloxone use to inform an increase in provider prescription of naloxone. The survey took place at a large Southern tertiary health center. An adapted REDCap survey utilizing validated questions was distributed via institutional e-mail listservs. The results (N = 181) were analyzed using descriptive and chi-square statistics. While 90.9% of the providers had heard of the strategy of prescribing naloxone to prevent overdose, only 72.1% of providers would have considered prescribing naloxone. Providers reported implementing treatment or referrals when informed about nonprescribed opioid use (49.4%), when informed about suspected opioid use disorder (50.6%), or when patients asked for opioid use treatment advice or referral (24.4%). Responses indicated that providers are aware of prescribing naloxone to prevent overdose; however, discrepancies existed between providers' knowledge and their willingness to prescribe naloxone. Providers' reluctance to prescribe is partially explained by unfamiliarity with the safety of naloxone and counseling practices surrounding the drug, as well as the belief that prescribing naloxone encourages continued nonprescribed use of opioids. To increase provider comfort, training programs surrounding the safety and counseling practices of naloxone should be implemented.</p>","PeriodicalId":16724,"journal":{"name":"Journal of Patient-Centered Research and Reviews","volume":"12 2","pages":"76-81"},"PeriodicalIF":1.6,"publicationDate":"2025-04-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12053811/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144025617","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The Use of Person-Centered Language in Scientific Research Articles Focused on Psychosis.","authors":"Zach Monahan, Tanner Stone, Vinay Swami, Kelly Dunn, Micah Hartwell","doi":"10.17294/2330-0698.2120","DOIUrl":"https://doi.org/10.17294/2330-0698.2120","url":null,"abstract":"<p><strong>Purpose: </strong>Societal stigma of psychosis leads to delayed treatment for individuals experiencing early symptoms, for fear of being labeled \"crazy\" or \"psychotic.\" Delayed treatment can worsen the prognosis of individuals with psychosis. Proper adherence to person-centered language (PCL) guidelines can curb the widely held stigmatized preconceptions about psychotic conditions.</p><p><strong>Methods: </strong>Our meta-epidemiological analysis began with a systematic search of literature in PubMed discussing psychosis from 2020-2022. From the 14,522 results, we randomly selected 500 articles in journals with at least 20 articles on psychosis (n=9,775), of which 241 articles met the inclusion criteria. These papers were screened for the usage of stigmatized language; article characteristics were also noted for further analysis.</p><p><strong>Results: </strong>Our analysis revealed that 53.1% of articles screened included stigmatized language. The most common stigmatized phrase identified was \"schizophrenia patient,\" found in 35.3% of papers. \"Schizophrenic [patient/subject/etc]\" and \"psychosis patient\" were each found in 12.4% of papers. The type of intervention (ie, pharmacologic, therapeutic, or observational) was the only variable that was found to be significant for PCL usage (P = 0.006).</p><p><strong>Conclusions: </strong>The majority of medical articles screened did not adhere to PCL guidelines. The usage of stigmatized language in literature reinforces the use of these labels in medical education, doctor's offices, and popular culture. Given the impact of stigma on treatment delay - and the poor prognosis that may result - proper care should be taken to enforce PCL in medical literature. Reducing the fear of labeling is a necessary step in encouraging treatment for people experiencing early symptoms of psychosis.</p>","PeriodicalId":16724,"journal":{"name":"Journal of Patient-Centered Research and Reviews","volume":"12 2","pages":"56-62"},"PeriodicalIF":1.6,"publicationDate":"2025-04-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12053813/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144031981","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Advancing a Patient- and Carer-Centered Approach for the Clinical Development of New Therapeutics for Aneurysmal Subarachnoid Hemorrhage: Insights From a Qualitative Study.","authors":"Sonya Abraham, Silvia Amaro, Ellyn Getz, Sylvia Herget, Gregory J Kato","doi":"10.17294/2330-0698.2119","DOIUrl":"https://doi.org/10.17294/2330-0698.2119","url":null,"abstract":"<p><p>Aneurysmal subarachnoid hemorrhage (aSAH) is characterized by a high rate of fatality and high risk of secondary brain injury. More treatment options are needed to improve outcomes. There are very few reports in the medical literature involving patient experience of aSAH, which is known for its unexpected onset and profound medical impact. Improved understanding of this patient experience would help make future clinical research more patient centered. To this end, we convened an advisory board consisting of aSAH patients and care partners in the United States. Participants emphasized the critical role that care partners play during hospitalization and in accessing supportive resources and rehabilitative care. Recommendations included improving the accessibility of clinical research information during the consent process with sensitivity to the stress and cognitive challenges of patients who have had an aSAH. Participants also recommended prioritizing in-person - either on-site or at-home - as opposed to remote follow-up visits because in-person communication can be easier for those recovering from aSAH. Insights from this study could be invaluable for the clinical development of new therapeutics for aSAH and other acute neurological conditions, with the goal of better meeting the needs of patients and their families during clinical research participation.</p>","PeriodicalId":16724,"journal":{"name":"Journal of Patient-Centered Research and Reviews","volume":"12 2","pages":"82-86"},"PeriodicalIF":1.6,"publicationDate":"2025-04-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12053810/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144016519","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}