Journal of Pharmaceutical and Allied Sciences最新文献_第3页

Comparative determination of trimethylamine in fresh beef samples marketed in Kaduna metropolis 卡杜纳市销售的新鲜牛肉样品中三甲胺的比较测定

Journal of Pharmaceutical and Allied Sciences Pub Date : 2013-01-01 DOI: 10.4314/JOPHAS.V10I2

V. Aina, Abdulsalami, A. Adewumi, W. Joyce, J. Ibrahim, O. Mamman

引用次数: 0

Added-on salt, socio-economic status and blood pressure in Nigerian adolescents 尼日利亚青少年的添加盐、社会经济地位和血压

Journal of Pharmaceutical and Allied Sciences Pub Date : 2013-01-01 DOI: 10.4314/JOPHAS.V10I3

A. Falodun, Anthony Adeyanju Udu-Cosi, O. Erharuyi, V. Imieje, J. E. Falodun, O. Agbonlahor, M. Hamann

{"title":"Added-on salt, socio-economic status and blood pressure in Nigerian adolescents","authors":"A. Falodun, Anthony Adeyanju Udu-Cosi, O. Erharuyi, V. Imieje, J. E. Falodun, O. Agbonlahor, M. Hamann","doi":"10.4314/JOPHAS.V10I3","DOIUrl":"https://doi.org/10.4314/JOPHAS.V10I3","url":null,"abstract":"Jatropha tanjorensis (L) (Fam – Euphorbiaceae), which has been consumed as leafy vegetable and as medicinal plant in Nigeria has shown hematological, antimalarial, antimicrobial, hypoglyceamic, hypolipidemic and antihypertensive activities. This review focuses on valuable knowledge of traditional uses, phytochemistry, and pharmacological activities of Jatopha tanjorensis against some tropical diseases, in order to highlight its therapeutic potentials with a view to integrate it into conventional medical use. Several classes of phytochemical compounds such as the polyphenols, saponins, tannins and alkaloids have been associated with the plant. It has also been shown to possess a wide spectrum of biological activities such as antiplasmodial (antimalarial), anti microbial, antiparasitic, antioxidant, anti-diabetic, antihypertensive, antihyperlipidemic and as remedy for anaemia. The review has thus provided a comprehensive and critical appraisal of the phytochemistry, pharmacology and toxicity of Jatropha tanjorensis in the tropics. Based on the findings of this work, future study on the phytochemistry and chemical constituents in relation to certain other biological activities are required to fully understand the phytochemical and complex pharmacological effect of the plant specie. Further work to isolate active compounds from the plant is also necessary. Keywords: Jatropha tanjorensis , Pharmacology, Phytochemistry, medicinal uses Journal of Pharmaceutical and Allied Sciences , Vol. 10 No. 3 (2013)","PeriodicalId":16719,"journal":{"name":"Journal of Pharmaceutical and Allied Sciences","volume":"70 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2013-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"79939349","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Forced Oxidative degradation study of Zolpidem tartrate by HPLC HPLC法研究酒石酸唑吡坦的强制氧化降解

Journal of Pharmaceutical and Allied Sciences Pub Date : 2012-01-01 DOI: 10.4314/JOPHAS.V9I2

P. Pushpalatha, R. Sarin, M. Rao, T. R. Baggi, M. Varma

引用次数: 0

Microbiological Examination of Ready-to-Eat Salads (Crispy Green) from Retail Establishments in the United Kingdom 英国零售机构即食沙拉(脆皮绿色)的微生物检验

Journal of Pharmaceutical and Allied Sciences Pub Date : 2012-01-01 DOI: 10.4314/JOPHAS.V9I1

Fo Enwa, Co Anie, T. Onyekaba

{"title":"Microbiological Examination of Ready-to-Eat Salads (Crispy Green) from Retail Establishments in the United Kingdom","authors":"Fo Enwa, Co Anie, T. Onyekaba","doi":"10.4314/JOPHAS.V9I1","DOIUrl":"https://doi.org/10.4314/JOPHAS.V9I1","url":null,"abstract":"A study of ready-to-eat salads (crispy Green) from retail establishments in the United Kingdom, was undertaken to determine their microbiological quality. The salads were collected and examined according to a standardized protocol. Total count was carried out and all colonies on CFC and MRS were counted as Pseudomona s and Lactobacilli respectively, while yeast and mould counts were obtained from RBCA agar. Only large dark colonies on VRBA agar were counted. E. coli enumeration was obtained from E. coli broth culture to check for acid and gas production which was found to be negative and a confirmatory test was carried out using tryptone water for indole production. This study has shown that there was a level of contamination associated with ready-to-eat salad in the U.K. The APC count was within the acceptable range according to the PHLS Guidelines. No growth of E. coli and Listeria was recorded showing that sample was satisfactory in that respect. For Pseudomonas there was a notable count due probably to the favourable temperature that suites their survival as they have the ability to grow at low temperature. There was also high count for yeast and mould , due possibly to their ability to grow at low temperature, with their optimum at 15-30 o C.","PeriodicalId":16719,"journal":{"name":"Journal of Pharmaceutical and Allied Sciences","volume":"22 1","pages":"1441-1444"},"PeriodicalIF":0.0,"publicationDate":"2012-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"88548901","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 2

Total Phenol amd Flavonoid contents of Crude Extract and Fractions of Picralima Nitida root bark TH. and H. Durand (Apoceanaceae) 黑木犀根皮粗提物和部位总酚和类黄酮含量的研究。和海棠科海棠

Journal of Pharmaceutical and Allied Sciences Pub Date : 2012-01-01 DOI: 10.4314/JOPHAS.V9I3

O. Erharuyi, A. Falodun

{"title":"Total Phenol amd Flavonoid contents of Crude Extract and Fractions of Picralima Nitida root bark TH. and H. Durand (Apoceanaceae)","authors":"O. Erharuyi, A. Falodun","doi":"10.4314/JOPHAS.V9I3","DOIUrl":"https://doi.org/10.4314/JOPHAS.V9I3","url":null,"abstract":"There is, as yet, no consensus on the relationship between anxiety and hypertension. While a few studies have investigated the topic in sub-Saharan Africa, there is no such literature in Nigeria. A cross-sectional study of 1654 apparently healthy young (mean age: 21.6±2.2 years), Nigerian adults (57.6% males) was conducted. Their blood pressures (BPs), weights and heights were measured using standard protocols. Body mass index (BMI) was calculated, and self-reported age at last birthday was recorded per subject. Anxiety was measured using the Beck Anxiety Inventory. Appropriate statistical tools were used to analyze the data generated. A total of 1.5% (1.6% for males and 1.4% for females, P = 0.561) had high degree of anxiety. Hypertension was found in 2.4% (4% for males and 0.1% for female, P = 0.043) of the population while prehypertension was found in 39.7% (53.2% for males and 21.5% for females, P = 0.05) between the low anxiety group and each of the moderate and high anxiety groups. No significant correlations or associations were found between BAI scores and systolic or diastolic BPs. Hypertension was not associated with anxiety in the studied population. The prevalence of both hypertension and anxiety in this population is one of the lowest in recorded literature. Further studies are warranted (especially in sub-Saharan Africa) to examine further, the hypothesis that both factors are associated. Keywords: anxiety, association, blood pressure, hypertension, young adults Journal of Pharmaceutical and Allied Sciences Vol. 9 No. 3 (2012)","PeriodicalId":16719,"journal":{"name":"Journal of Pharmaceutical and Allied Sciences","volume":"3 1","pages":"1564-1576"},"PeriodicalIF":0.0,"publicationDate":"2012-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"75606780","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 6

Storage practices in the developing world: A survey of Nigerian households 发展中国家的储存做法:对尼日利亚家庭的调查

Journal of Pharmaceutical and Allied Sciences Pub Date : 2011-07-20 DOI: 10.4314/JOPHAS.V8I1.68144

E. Enato, Aa Sounyo, T. Einarson

{"title":"Storage practices in the developing world: A survey of Nigerian households","authors":"E. Enato, Aa Sounyo, T. Einarson","doi":"10.4314/JOPHAS.V8I1.68144","DOIUrl":"https://doi.org/10.4314/JOPHAS.V8I1.68144","url":null,"abstract":"Proper drug storage is essential, especially in tropical climates. Failure to do so can result in substrength products which can cause treatment failures. Little research has been done in Africa to examine this aspect of healthcare. The objectives of this study were to determine the pattern of drug storage at home in some communities in Nigeria, and to assess the conditions under which medicines are kept. A survey of households in some communities in Edo State, Nigeria, was undertaken using a validated questionnaire. Information on types of medication, dosage form, cost, source, and quantity stored in households, and reasons for using a particular storage facility were collected. Data were entered into Excel spreadsheet and sorted based on the research theme. Thereafter, the frequency distributions of the responses were determined. Of the 497 respondents surveyed, 209 (42.1%) indicated that they kept a total of 490 drugs on hand in their homes. The average number of drugs on hand among those who reported having them was 2.3±1.3 (median 2), the cost of which ranged from 10-2000 naira (USD $0.07-$13.33). Analgesics (43.7%), vitamins and nutrients (19.7%), and anti-malarial drugs (11.8%) were the most frequently stored classes of medicine. A majority of household medicines were stored in cellophane bag (36.9%), followed by closed cupboard or drawer (25.9%), and household containers (9.6%). The study reveals the frequency of household stored medicines in Nigerian communities, which often were kept in suboptimal conditions. The implications of this practice along with recommendations for appropriate behaviors are discussed.","PeriodicalId":16719,"journal":{"name":"Journal of Pharmaceutical and Allied Sciences","volume":"31 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2011-07-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"76891681","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 2

A study on antinociceptive, antiinflammatory and antidiarrhoeal activities of vallaris solanacea (roth) kuntze bark extracts 缬草昆山树皮提取物抗炎、抗炎、抗腹泻作用的研究

Journal of Pharmaceutical and Allied Sciences Pub Date : 2011-07-20 DOI: 10.4314/JOPHAS.V8I1.68148

R. Ashikur, H. Ekramul, Hasanuzzaman, S. Muhuri, I. Shahid

引用次数: 2

Health status and pregnancy experience of pregnant women in a rural community, Gamashina of Kano State 卡诺州Gamashina农村社区孕妇的健康状况和妊娠经历

Journal of Pharmaceutical and Allied Sciences Pub Date : 2011-07-20 DOI: 10.4314/JOPHAS.V8I1.68146

H. Isah, B. Uko

{"title":"Health status and pregnancy experience of pregnant women in a rural community, Gamashina of Kano State","authors":"H. Isah, B. Uko","doi":"10.4314/JOPHAS.V8I1.68146","DOIUrl":"https://doi.org/10.4314/JOPHAS.V8I1.68146","url":null,"abstract":"Significant stress with deleterious impact on the health of a pregnant woman is a known occurrence in the course of pregnancy. This study explored the variations in health profile of rural pregnant women in Northern Nigerian rural setting. Records of a cohort of 340 pregnant women provided ANC services in a rural faith-based PHC facility were reviewed to ascertain their obstetric care seeking behaviour, pregnancy experience and health profile in the course of their pregnancies, and fetal outcome using a template to abstract relevant information. Descriptive statistics were used to examine the trends in their health status over the course of their pregnancy through to delivery. Mean booking and pre-delivery maternal weights were 53.35 kg and 55.83 kg respectively. 62.17% were found to have lost weight in the course of their pregnancies, while 21.31% had no change in weight, and 16.52% had varying degrees of weight appreciation. Mean booking haemoglobin value was 12.96%. Poor obstetric care seeking behaviour was a notable finding as 55.65% terminated their ANC access before the 34th week of gestation. High homebased obstetric services as shown by home deliveries and by untrained traditional birth attendants were high (90.88%). Poor pregnancy outcome as depicted by low birth weight (mean birth weight of 2.93 kg) and high stillbirth (48.19%) were found. More comprehensive maternal and child health services that are community-driven is recommended; and it is imperative that the traditional and community obstetric care providers and its system be harnessed. In addition, there is the need to vigorously put on ground, programmes for ensuring women especially rural women empowerment and for paying more attention to rural pregnant women due to their high risk nature from their marginal health profile prior to and during pregnancy.","PeriodicalId":16719,"journal":{"name":"Journal of Pharmaceutical and Allied Sciences","volume":"112 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2011-07-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"79308052","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Evaluation of the suspending properties of Adansonia digitata gum on Sulphadimidine Suspension 丹参胶在磺胺悬浮液上悬浮性能的评价

Journal of Pharmaceutical and Allied Sciences Pub Date : 2011-07-20 DOI: 10.4314/JOPHAS.V8I1.68149

J. Audu-Peter, Jo Kadiri, As Ogianakhu

{"title":"Evaluation of the suspending properties of Adansonia digitata gum on Sulphadimidine Suspension","authors":"J. Audu-Peter, Jo Kadiri, As Ogianakhu","doi":"10.4314/JOPHAS.V8I1.68149","DOIUrl":"https://doi.org/10.4314/JOPHAS.V8I1.68149","url":null,"abstract":"Adansonia digitata gum was extracted from the dried leaves of Adansonia digitata using hot and cold water extraction processes yielding 16 and 18 % w/w respectively. The suspending properties of the hot (HWE) and cold water (CWE) gum extracts, used at 1-5 % w/w concentration levels were evaluated and compared with Compound Tragacanth (4% w/v) in sulphadimidine suspension. Sedimentation volume and rate, rheology, and ease of redispersion were employed as evaluation parameters. The results showed that both hot and cold water extracts of the gum used at 2-3 % w/v produced a better suspending property than 4 % w/v Compound Tragacanth gum. The suspending ability of the gums was in the order of: CWE > HWE > Compound Tragacanth. When the viscosity of HWE was compared with CWE for 15 days, they were found to differ significantly (P< 0.05). Also, when the viscosity of either hot or cold water gum extracts were compared with that of Compound Tragacanth at the same concentration for 15 days, there was a significant difference (P< 0.05). At all concentrations of gums used, the CWE had the better suspending property. Keywords: Adansonia digitata , suspending agents, rheology, ease of re-dispersibility, sedimentation rate","PeriodicalId":16719,"journal":{"name":"Journal of Pharmaceutical and Allied Sciences","volume":"78 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2011-07-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"90604344","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

Wound healing properties of stem bark extract of Tabebuia rosea 蔷薇茎皮提取物的伤口愈合特性

Journal of Pharmaceutical and Allied Sciences Pub Date : 2011-02-08 DOI: 10.4314/JOPHAS.V7I4.63452

P. Nwonu, T. Okoye, P. Akah, A. Ezike, Ia Ejindu, Se Eneh

引用次数: 1