Total Phenol amd Flavonoid contents of Crude Extract and Fractions of Picralima Nitida root bark TH. and H. Durand (Apoceanaceae)

O. Erharuyi, A. Falodun
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引用次数: 6

Abstract

There is, as yet, no consensus on the relationship between anxiety and hypertension. While a few studies have investigated the topic in sub-Saharan Africa, there is no such literature in Nigeria. A cross-sectional study of 1654 apparently healthy young (mean age: 21.6±2.2 years), Nigerian adults (57.6% males) was conducted. Their blood pressures (BPs), weights and heights were measured using standard protocols. Body mass index (BMI) was calculated, and self-reported age at last birthday was recorded per subject. Anxiety was measured using the Beck Anxiety Inventory. Appropriate statistical tools were used to analyze the data generated. A total of 1.5% (1.6% for males and 1.4% for females, P = 0.561) had high degree of anxiety. Hypertension was found in 2.4% (4% for males and 0.1% for female, P = 0.043) of the population while prehypertension was found in 39.7% (53.2% for males and 21.5% for females, P = 0.05) between the low anxiety group and each of the moderate and high anxiety groups. No significant correlations or associations were found between BAI scores and systolic or diastolic BPs. Hypertension was not associated with anxiety in the studied population. The prevalence of both hypertension and anxiety in this population is one of the lowest in recorded literature. Further studies are warranted (especially in sub-Saharan Africa) to examine further, the hypothesis that both factors are associated. Keywords: anxiety, association, blood pressure, hypertension, young adults Journal of Pharmaceutical and Allied Sciences Vol. 9 No. 3 (2012)
黑木犀根皮粗提物和部位总酚和类黄酮含量的研究。和海棠科海棠
植物中含有大量酚类化合物,是人类饮食的重要组成部分。在非洲民间医药中,特别是在西非地区,野檀被广泛使用。本研究测定了牛蒡子提取物及其组分中总酚和总黄酮的含量。采用Folin-Ciocalteu法测定了烟草根皮甲醇提取物及其组分的酚类含量。采用标准法测定总黄酮含量。采用单因素方差分析(ANOVA)确定差异有统计学意义,采用Duncan 's multiple range (DMR)检验确定均数差异。结果表明,粗甲醇提取物的总酚和总黄酮含量显著高于各馏分(P < 0.05);粗甲醇提取物的总酚和总黄酮含量分别为没食子酸当量(GAE) 94.92±9.50 mg /g和槲皮素当量(QE) 46.46±3.30 mg /g。结果表明,小木贼根皮提取物中酚含量较高,提取方法是影响小木贼根皮中酚含量的主要因素。关键词:酚含量;类黄酮;提取;
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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