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Prevalence of Micro and Macrovascular Complications and Assessment of Risk Factors in Diabetic patients: a Prospective Observational Study 糖尿病患者微血管和大血管并发症患病率及危险因素评估:一项前瞻性观察研究
Journal of Pharmaceutical Research Pub Date : 2021-09-15 DOI: 10.18579/jopcr/v20i3.ms21056
D. Jothieswari, R. M. Soniya, R. S. Vinuthna, P. Venkatesh, V. Hari
{"title":"Prevalence of Micro and Macrovascular Complications and Assessment of Risk Factors in Diabetic patients: a Prospective Observational Study","authors":"D. Jothieswari, R. M. Soniya, R. S. Vinuthna, P. Venkatesh, V. Hari","doi":"10.18579/jopcr/v20i3.ms21056","DOIUrl":"https://doi.org/10.18579/jopcr/v20i3.ms21056","url":null,"abstract":"Diabetes is a chronic metabolic disorder of heterogenous type. Diabetic complications are mostly associated with condition of vascular penetrability that affects different tissues & kidneys, retina, nerves which involve the body organs.The aim of study was to assess the prevalence of micro and macro diabetic complications and risk factors of diabetic patients. The prospective observational study was conducted in Raghu Diabetes and general clinic, Chittoor, Andhra Pradesh. A sample size of 200 subjects was recruited for the study. The study was conducted from December 2020 to May 2021. Patients with age group of 30-90 years and diabetic complications were included in the study. Patients below 30 years of age were excluded from study. The patient details were collected using questionnaire form. It contains sociodemographic data and medical history including smoking, alcohol, family history of diabetes mellitus, and treatment and management of diabetes. The statistical analysis was carried out using SPSS version 25.0. The study results showed 1.5% of patients had more than two co-morbidities, which was significantly higher among elderly (5.04%), females (5.2%) and urban residence (6.31%), physical inactivity (3.15%) and house wife (2.1%). The statins prescribed patients were 160 (80%) whereas patients on other medications, insulin in combination with OHA38(19%),andmultivitaminsprescribedpatients181(90.5%).Thestudyshowedthepatient’sageof51-70yearswasmostlyaffectedbydiabetes.Regularexercise,intakeofmorevegetablesandfruitsandadoptingahealthierlife-stylecanreducetheprevalenceofdiabetes.","PeriodicalId":16706,"journal":{"name":"Journal of Pharmaceutical Research","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2021-09-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46378261","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
A Study on the Knowledge and Attitude of the Ayurvedic and Dental Undergraduates of Central India towards ACLS and BLS 印度中部阿育吠陀和牙科本科生对ACLS和BLS的知识和态度研究
Journal of Pharmaceutical Research Pub Date : 2021-09-14 DOI: 10.9734/JPRI/2021/V33I43B32569
Anjali Bankar, Amit Reche, K. Chhabra, P. Madhu, Mehek Batra, Radhika kannake, Ramani Mandale
{"title":"A Study on the Knowledge and Attitude of the Ayurvedic and Dental Undergraduates of Central India towards ACLS and BLS","authors":"Anjali Bankar, Amit Reche, K. Chhabra, P. Madhu, Mehek Batra, Radhika kannake, Ramani Mandale","doi":"10.9734/JPRI/2021/V33I43B32569","DOIUrl":"https://doi.org/10.9734/JPRI/2021/V33I43B32569","url":null,"abstract":"","PeriodicalId":16706,"journal":{"name":"Journal of Pharmaceutical Research","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2021-09-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"47578625","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Occurrence of Hemorrhoids and Anal Fissures through Pregnancy and Postpartum 妊娠和产后痔疮和肛裂的发生
Journal of Pharmaceutical Research Pub Date : 2021-09-07 DOI: 10.9734/JPRI/2021/V33I43A32497
Esmatullah, Baseera
{"title":"Occurrence of Hemorrhoids and Anal Fissures through Pregnancy and Postpartum","authors":"Esmatullah, Baseera","doi":"10.9734/JPRI/2021/V33I43A32497","DOIUrl":"https://doi.org/10.9734/JPRI/2021/V33I43A32497","url":null,"abstract":"Objective: To recognize occurrence also danger issues of hemorrhoids and fissures throughout pregnancy and afterwards childbirth. \u0000Population: The overall 180 pregnant females trailed up till 1 month after delivery. \u0000Methods: Females remained inspected 4 times via pregnancy and after delivery; those that developed perianal diseases were compared with those that did not. Main outcome measures Incidence, time and risk factors of hemorrhoids and fissures. Our current research was done in Nangarhar Reginal Hospital Gyn/ Obs ward from June -2020 to June -2021.  \u0000Results: In total 90 (50%) female patients have developed perineal diseases (Hemorrhoid, Anal Fissure. The most vulnerable times were 3rd trimester about 60 (66.6%), Second trimester 20(22.2%) and in the first month after deliver 10(11.11%). \u0000From these Patients Investigation shows that 65(72.2%) only suffering from hemorrhoid and 15(13.5%) has both hemorrhoid and anal fissure. 80 female undergone Vaginal delivery and 10 remind has undergone of caesarean section. Risk Factors for Perineal illness during pregnancy was Constipation, Straining throughout delivery for more than 20 mins and baby weight >3900gr. \u0000Conclusions: Hemorrhoids and fissures remain mutual throughout last trimester of pregnancy and one month afterwards delivery, through constipation, individual past of hemorrhoids or fissures, birth weight of new >3900 g, straining throughout delivery for extra than 20 mins being self-sufficiently related risk factors.","PeriodicalId":16706,"journal":{"name":"Journal of Pharmaceutical Research","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2021-09-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"45688377","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Evaluation of Antioxidant Property of Moringa Oleifera Leaves and its Effectiveness Against Rheumatoid Arthritis 辣木叶抗氧化性能及其对类风湿性关节炎的疗效评价
Journal of Pharmaceutical Research Pub Date : 2021-08-23 DOI: 10.9734/JPRI/2021/V33I41B32358
M. J. Kapil, D. Deka, M. Lahkar, N. Sharma
{"title":"Evaluation of Antioxidant Property of Moringa Oleifera Leaves and its Effectiveness Against Rheumatoid Arthritis","authors":"M. J. Kapil, D. Deka, M. Lahkar, N. Sharma","doi":"10.9734/JPRI/2021/V33I41B32358","DOIUrl":"https://doi.org/10.9734/JPRI/2021/V33I41B32358","url":null,"abstract":"The present study is performed with the purpose of evaluating the antioxidant nature of Moringa Oleifera leaves and the effectiveness of the leaf extract against the disease called Rheumatoid Arthritis. The disease is very chronic and it is a common disease. So the study is focused on the medicinal properties of Moringa Oleifera leaves, chemical composition of Moringa Oleifera leaves and seeds, the antioxidant nature of moringa leaves and its extracts, the effectiveness of moringa leaf extract against the Rheumatoid Arthritis disease, reason behind the effectiveness of moringa leaves and discussion and analysis of the result generated.","PeriodicalId":16706,"journal":{"name":"Journal of Pharmaceutical Research","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2021-08-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46607018","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 2
Effects of Solvents and Extraction Methods on Naringenin, LC-MS Based Quantitative Studies and Major Metabolite of Cochlospermum gossypium 溶剂和提取方法对棉蚜Naringenin、LC-MS定量研究及主要代谢产物的影响
Journal of Pharmaceutical Research Pub Date : 2021-08-23 DOI: 10.9734/JPRI/2021/V33I41B32361
Y. Rajendra, K. Sunitha
{"title":"Effects of Solvents and Extraction Methods on Naringenin, LC-MS Based Quantitative Studies and Major Metabolite of Cochlospermum gossypium","authors":"Y. Rajendra, K. Sunitha","doi":"10.9734/JPRI/2021/V33I41B32361","DOIUrl":"https://doi.org/10.9734/JPRI/2021/V33I41B32361","url":null,"abstract":"Aim: The present study was aimed to investigate “Effects of Solvents and Extraction Methods on Naringenin, LC-MS Based Quantitative Studies and major Metabolite of Cochlospermum Gossypium”. \u0000Study Design: LC-MS based Quantification Studies. \u0000Place and Duration of Study: Department of Pharmaceutical Chemistry, GITAM Institute of Pharmacy, Visakhapatnam, Andhra Pradesh between April 2019 and July 2020. \u0000Methodology: Rapid and Quantitative efficient extraction methods were used by using soxhlet and Ultrasound mediated extraction techniques for a range of polar solvents and Isolation of Naringenin by gradient elution technique, In the present study Naringenin was isolated in abundance (1%) by repetitive chromatographic purifications of the ethyl acetate extract of the bark part of C.gossypium. In view of high therapeutic potential, detailed HPLC based quantitative studies was carried out on C. gossypium bark, which contains significant levels of Naringenin. \u0000Results: The chromatographic separation was performed on the stationary phase, based on different retention mechanisms due to hydrophilic and hydrophobic interactions between compounds and stationary phase. In total, 24 different polar extracts were generated by soxhlet and ultrasound extraction methods from the two bark samples which were collected from Jaipur town (Telangana state) and Trichur town (Kerala state). \u0000Conclusion: The highest Naringenin content (0.59%) was found in the methanol + chloroform (1:1) extract (E8) generated by direct Soxhlet extraction of C.gossypium bark collected from Jaipur (Telangana state).Naringenin was isolated from a non-citrus plant for first time from Cochlospermum gosspyium and more significantly it is isolated in large quantity. It was obtained in 99.9% purity as shown by LCMS.","PeriodicalId":16706,"journal":{"name":"Journal of Pharmaceutical Research","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2021-08-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44038847","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The Impact of Metformin in Pediatric Type-1 Diabetes Mellitus in Addition to Insulin Therapy; Literature Review 二甲双胍与胰岛素治疗对儿童1型糖尿病的影响文献综述
Journal of Pharmaceutical Research Pub Date : 2021-08-23 DOI: 10.9734/JPRI/2021/V33I41B32357
Mohammed Abdullah Alzahimah, Khalid Mohammed S. Al Sleem, Hatem Ahmed Albenawy, Albara Abdullah Mohammed Al Mushham
{"title":"The Impact of Metformin in Pediatric Type-1 Diabetes Mellitus in Addition to Insulin Therapy; Literature Review","authors":"Mohammed Abdullah Alzahimah, Khalid Mohammed S. Al Sleem, Hatem Ahmed Albenawy, Albara Abdullah Mohammed Al Mushham","doi":"10.9734/JPRI/2021/V33I41B32357","DOIUrl":"https://doi.org/10.9734/JPRI/2021/V33I41B32357","url":null,"abstract":"","PeriodicalId":16706,"journal":{"name":"Journal of Pharmaceutical Research","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2021-08-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43957988","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Studies of Serum Calcium, Inorganic Phosphate and Magnesium Levels in Lactating Mothers in Owerri Owerri哺乳期母亲血清钙、无机磷和镁水平的研究
Journal of Pharmaceutical Research Pub Date : 2021-08-23 DOI: 10.9734/JPRI/2021/V33I41B32360
A. Edward, E. Obeagu, H. Okorie, C. Vincent, Yakubu Sunday Bot
{"title":"Studies of Serum Calcium, Inorganic Phosphate and Magnesium Levels in Lactating Mothers in Owerri","authors":"A. Edward, E. Obeagu, H. Okorie, C. Vincent, Yakubu Sunday Bot","doi":"10.9734/JPRI/2021/V33I41B32360","DOIUrl":"https://doi.org/10.9734/JPRI/2021/V33I41B32360","url":null,"abstract":"","PeriodicalId":16706,"journal":{"name":"Journal of Pharmaceutical Research","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2021-08-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46937093","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 4
Comparative Analysis of Differentially Expressed Genes in Oral Leukoplakia and Oral Submucous Fibrosis Using Bioinformatics Approach 应用生物信息学方法比较分析口腔白斑和口腔黏膜下纤维化差异表达基因
Journal of Pharmaceutical Research Pub Date : 2021-08-23 DOI: 10.9734/JPRI/2021/V33I41B32356
Akansha Budakoti, C. More, A. Seth, Priyanka Sharma
{"title":"Comparative Analysis of Differentially Expressed Genes in Oral Leukoplakia and Oral Submucous Fibrosis Using Bioinformatics Approach","authors":"Akansha Budakoti, C. More, A. Seth, Priyanka Sharma","doi":"10.9734/JPRI/2021/V33I41B32356","DOIUrl":"https://doi.org/10.9734/JPRI/2021/V33I41B32356","url":null,"abstract":"","PeriodicalId":16706,"journal":{"name":"Journal of Pharmaceutical Research","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2021-08-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43845011","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
A Review On: Nutraceuticals Challenges in Formulation and Its Regulatory Aspects 营养保健品在配方和监管方面的挑战综述
Journal of Pharmaceutical Research Pub Date : 2021-07-12 DOI: 10.33140/jpr.06.02.01
{"title":"A Review On: Nutraceuticals Challenges in Formulation and Its Regulatory Aspects","authors":"","doi":"10.33140/jpr.06.02.01","DOIUrl":"https://doi.org/10.33140/jpr.06.02.01","url":null,"abstract":"Nutraceuticals have sparked great attention because of their perceived safety, The current article focuses on the need for appropriate diets, health issues associated with failure to adhere to the known healthy eating models, development of new nutraceuticals/functional foods/food supplements with novel health benefits, elucidation mechanisms of action of these products, and to define and understand the analytical, challenges during the formulation of different dosage form, current scenario in India, future and regulatory aspects of nutraceuticals. the Indian industry and regulatory scenario are relatively nascent and have great potential to develop and compete with other international agencies. This is a rapidly growing industry in India and several initiatives have been taken in this direction to make India one of the key future players in the area of nutraceuticals. This article can help you stay up to date on the latest advancements in nutraceutical research.","PeriodicalId":16706,"journal":{"name":"Journal of Pharmaceutical Research","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2021-07-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44184777","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Nano-Fertilizers - A Cutting Edge Approach for Sustainable Agriculture 纳米肥料-可持续农业的前沿方法
Journal of Pharmaceutical Research Pub Date : 2021-07-12 DOI: 10.33140/jpr.06.02.02
{"title":"Nano-Fertilizers - A Cutting Edge Approach for Sustainable Agriculture","authors":"","doi":"10.33140/jpr.06.02.02","DOIUrl":"https://doi.org/10.33140/jpr.06.02.02","url":null,"abstract":"Nanostructured fertilizers or nano-fertilizers are in the form of nanocarriers, nanocapsules or nanonutrients that should be considered as smart fertilizers that can improve plant nutrient utilization efficiency, control nutrient release and reduce environmental impact. However, there is an urgent need to standardize and evaluate the toxicity of nanomaterials used in the synthesis of nano-fertilizers. Therefore, detailed agricultural field and greenhouse surveys are highly recommended for performance evaluation of nano-fertilizers.","PeriodicalId":16706,"journal":{"name":"Journal of Pharmaceutical Research","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2021-07-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48189796","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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