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Journal of Pharmaceutical Investigation最新文献

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Synthesis, physicochemical properties, and protective effects of a novel water-soluble tetrahydrocurcumin-diglutaric acid prodrug on ethanol-induced toxicity in HepG2 cells 新型水溶性四氢姜黄素-二己二酸前药的合成、理化性质及对HepG2细胞乙醇毒性的保护作用
IF 5.5 4区 医学
Journal of Pharmaceutical Investigation Pub Date : 2022-05-21 DOI: 10.1007/s40005-022-00576-w
Nattapong Jongjitphisut, Rianthong Phumsuay, Worathat Thitikornpong, P. Rashatasakhon, C. Muangnoi, O. Vajragupta, P. Rojsitthisak
{"title":"Synthesis, physicochemical properties, and protective effects of a novel water-soluble tetrahydrocurcumin-diglutaric acid prodrug on ethanol-induced toxicity in HepG2 cells","authors":"Nattapong Jongjitphisut, Rianthong Phumsuay, Worathat Thitikornpong, P. Rashatasakhon, C. Muangnoi, O. Vajragupta, P. Rojsitthisak","doi":"10.1007/s40005-022-00576-w","DOIUrl":"https://doi.org/10.1007/s40005-022-00576-w","url":null,"abstract":"","PeriodicalId":16702,"journal":{"name":"Journal of Pharmaceutical Investigation","volume":"52 1","pages":"477 - 487"},"PeriodicalIF":5.5,"publicationDate":"2022-05-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41389838","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 2
Alginate-coated chitosan nanoparticles protect protein drugs from acid degradation in gastric media 海藻酸盐包覆的壳聚糖纳米粒子保护蛋白质药物免受胃介质中的酸降解
IF 5.5 4区 医学
Journal of Pharmaceutical Investigation Pub Date : 2022-05-12 DOI: 10.1007/s40005-022-00574-y
Phuong Tran, J. Park
{"title":"Alginate-coated chitosan nanoparticles protect protein drugs from acid degradation in gastric media","authors":"Phuong Tran, J. Park","doi":"10.1007/s40005-022-00574-y","DOIUrl":"https://doi.org/10.1007/s40005-022-00574-y","url":null,"abstract":"","PeriodicalId":16702,"journal":{"name":"Journal of Pharmaceutical Investigation","volume":"52 1","pages":"465 - 476"},"PeriodicalIF":5.5,"publicationDate":"2022-05-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44956289","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 5
Dissociation mechanics and stability of type A botulinum neurotoxin complex by means of biophysical evaluation A型肉毒杆菌神经毒素复合物的解离机理及稳定性的生物物理评价
IF 5.5 4区 医学
Journal of Pharmaceutical Investigation Pub Date : 2022-04-08 DOI: 10.1007/s40005-022-00570-2
Shavron Hada, Jae Chul Lee, E. Lee, Sunkyong Ji, Jeong Sun Nam, B. Yun, D. Na, N. Kim, S. Jeong
{"title":"Dissociation mechanics and stability of type A botulinum neurotoxin complex by means of biophysical evaluation","authors":"Shavron Hada, Jae Chul Lee, E. Lee, Sunkyong Ji, Jeong Sun Nam, B. Yun, D. Na, N. Kim, S. Jeong","doi":"10.1007/s40005-022-00570-2","DOIUrl":"https://doi.org/10.1007/s40005-022-00570-2","url":null,"abstract":"","PeriodicalId":16702,"journal":{"name":"Journal of Pharmaceutical Investigation","volume":"52 1","pages":"453 - 463"},"PeriodicalIF":5.5,"publicationDate":"2022-04-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44952643","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
Mitigating off-target distribution and enhancing cytotoxicity in breast cancer cells with alpha-ketoglutaric acid-modified Fe/Mg-CA nanoparticles α -酮戊二酸修饰的Fe/Mg-CA纳米颗粒减轻乳腺癌细胞的脱靶分布并增强细胞毒性
IF 5.5 4区 医学
Journal of Pharmaceutical Investigation Pub Date : 2022-04-05 DOI: 10.1007/s40005-022-00571-1
Sheikh Tanzina Haque, Md Emranul Karim, Iekhsan Othman, E. Chowdhury
{"title":"Mitigating off-target distribution and enhancing cytotoxicity in breast cancer cells with alpha-ketoglutaric acid-modified Fe/Mg-CA nanoparticles","authors":"Sheikh Tanzina Haque, Md Emranul Karim, Iekhsan Othman, E. Chowdhury","doi":"10.1007/s40005-022-00571-1","DOIUrl":"https://doi.org/10.1007/s40005-022-00571-1","url":null,"abstract":"","PeriodicalId":16702,"journal":{"name":"Journal of Pharmaceutical Investigation","volume":"52 1","pages":"367 - 386"},"PeriodicalIF":5.5,"publicationDate":"2022-04-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42116591","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 4
Recent advancements in lipid–mRNA nanoparticles as a treatment option for cancer immunotherapy 脂质mrna纳米颗粒作为癌症免疫治疗选择的最新进展
IF 5.5 4区 医学
Journal of Pharmaceutical Investigation Pub Date : 2022-03-26 DOI: 10.1007/s40005-022-00569-9
Prajeena Karmacharya, B. R. Patil, Jong Oh Kim
{"title":"Recent advancements in lipid–mRNA nanoparticles as a treatment option for cancer immunotherapy","authors":"Prajeena Karmacharya, B. R. Patil, Jong Oh Kim","doi":"10.1007/s40005-022-00569-9","DOIUrl":"https://doi.org/10.1007/s40005-022-00569-9","url":null,"abstract":"","PeriodicalId":16702,"journal":{"name":"Journal of Pharmaceutical Investigation","volume":"52 1","pages":"415 - 426"},"PeriodicalIF":5.5,"publicationDate":"2022-03-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46234350","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 12
Micronization of a poorly water-soluble drug, fenofibrate, via supercritical-fluid-assisted spray-drying 水溶性差的药物非诺贝特的超临界流体辅助喷雾干燥微粉化
IF 5.5 4区 医学
Journal of Pharmaceutical Investigation Pub Date : 2022-03-24 DOI: 10.1007/s40005-022-00565-z
Jeong‐Soo Kim, Heejun Park, K. Kang, Eun-Sol Ha, Min‐Soo Kim, Sung-Joo Hwang
{"title":"Micronization of a poorly water-soluble drug, fenofibrate, via supercritical-fluid-assisted spray-drying","authors":"Jeong‐Soo Kim, Heejun Park, K. Kang, Eun-Sol Ha, Min‐Soo Kim, Sung-Joo Hwang","doi":"10.1007/s40005-022-00565-z","DOIUrl":"https://doi.org/10.1007/s40005-022-00565-z","url":null,"abstract":"","PeriodicalId":16702,"journal":{"name":"Journal of Pharmaceutical Investigation","volume":"52 1","pages":"353 - 366"},"PeriodicalIF":5.5,"publicationDate":"2022-03-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48648393","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 10
Recent studies on modulating hyaluronic acid-based hydrogels for controlled drug delivery 调节透明质酸基水凝胶以控制药物递送的研究进展
IF 5.5 4区 医学
Journal of Pharmaceutical Investigation Pub Date : 2022-03-19 DOI: 10.1007/s40005-022-00568-w
Min-Hwan Kim, D. Nguyen, Dae Kim
{"title":"Recent studies on modulating hyaluronic acid-based hydrogels for controlled drug delivery","authors":"Min-Hwan Kim, D. Nguyen, Dae Kim","doi":"10.1007/s40005-022-00568-w","DOIUrl":"https://doi.org/10.1007/s40005-022-00568-w","url":null,"abstract":"","PeriodicalId":16702,"journal":{"name":"Journal of Pharmaceutical Investigation","volume":"52 1","pages":"397 - 413"},"PeriodicalIF":5.5,"publicationDate":"2022-03-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42924021","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 10
The combined effects of telmisartan and ramipril on hypertension and cardiovascular injury 替米沙坦与雷米普利联合用药对高血压及心血管损伤的影响
IF 5.5 4区 医学
Journal of Pharmaceutical Investigation Pub Date : 2022-03-18 DOI: 10.1007/s40005-022-00567-x
Do-Hyung Lee, Min-Tae Kim, Hyung-Won Lee, Joo-Hui Han, C. Myung
{"title":"The combined effects of telmisartan and ramipril on hypertension and cardiovascular injury","authors":"Do-Hyung Lee, Min-Tae Kim, Hyung-Won Lee, Joo-Hui Han, C. Myung","doi":"10.1007/s40005-022-00567-x","DOIUrl":"https://doi.org/10.1007/s40005-022-00567-x","url":null,"abstract":"","PeriodicalId":16702,"journal":{"name":"Journal of Pharmaceutical Investigation","volume":"52 1","pages":"443 - 451"},"PeriodicalIF":5.5,"publicationDate":"2022-03-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48081335","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 3
Effects of 1α,25-dihydroxyvitamin D3 on the pharmacokinetics and biodistribution of ergothioneine, an endogenous organic cation/carnitine transporter 1 substrate, in rats 1α，25-二羟基维生素D3对内源性有机阳离子/肉毒碱转运蛋白1底物麦角硫因在大鼠体内的药代动力学和生物分布的影响
IF 5.5 4区 医学
Journal of Pharmaceutical Investigation Pub Date : 2022-03-10 DOI: 10.1007/s40005-022-00563-1
Dang-Khoa Vo, Thi-Thao-Linh Nguyen, H. Maeng
{"title":"Effects of 1α,25-dihydroxyvitamin D3 on the pharmacokinetics and biodistribution of ergothioneine, an endogenous organic cation/carnitine transporter 1 substrate, in rats","authors":"Dang-Khoa Vo, Thi-Thao-Linh Nguyen, H. Maeng","doi":"10.1007/s40005-022-00563-1","DOIUrl":"https://doi.org/10.1007/s40005-022-00563-1","url":null,"abstract":"","PeriodicalId":16702,"journal":{"name":"Journal of Pharmaceutical Investigation","volume":"52 1","pages":"341 - 351"},"PeriodicalIF":5.5,"publicationDate":"2022-03-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"47732166","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 4
Three-Dimensional Printing for Oral Pharmaceutical Dosage Forms 口服药物剂型的三维打印
IF 5.5 4区 医学
Journal of Pharmaceutical Investigation Pub Date : 2022-03-07 DOI: 10.1007/s40005-022-00561-3
Ji Hoon Kim, Kyeong-Lim Kim, Hyo-Eon Jin
{"title":"Three-Dimensional Printing for Oral Pharmaceutical Dosage Forms","authors":"Ji Hoon Kim, Kyeong-Lim Kim, Hyo-Eon Jin","doi":"10.1007/s40005-022-00561-3","DOIUrl":"https://doi.org/10.1007/s40005-022-00561-3","url":null,"abstract":"","PeriodicalId":16702,"journal":{"name":"Journal of Pharmaceutical Investigation","volume":"52 1","pages":"293 - 317"},"PeriodicalIF":5.5,"publicationDate":"2022-03-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48582871","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 7
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