{"title":"Erector Spinae Plane Block in Patients with Low Back Pain","authors":"J. Hong, S. Shin, E. Cho","doi":"10.46308/kmj.2022.00122","DOIUrl":"https://doi.org/10.46308/kmj.2022.00122","url":null,"abstract":"The erector spinae plane (ESP) block is a novel interfascial block technique to relieve various postoperative pain. We described successful management of acute or sub-acute low back pain in 3 patients using ultrasound guided ESP blocks. Three patients of low back pain visited our pain clinic with variable duration of pain development with numerical rating scale 7. Before the visit of pain clinic, they were treated with physical therapy and acupuncture with minimal efficacy. For their pain relief, lumbar ESP block at L4 or L5 level using ultrasound guidance was performed. After lumbar ESP block, all 3 patients showed good treatment effect in relieving their low back pain (numerical rating scale 1-2). This effect was maintained even after 2 months after injection. Lumbar ESP block is a good treatment option for acute or subacute low back pain. Further studies are needed to clarify the clinical efficacy.","PeriodicalId":166951,"journal":{"name":"Keimyung Medical Journal","volume":"121 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-12-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"126301830","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Insomnia Severity and Its Influencing Factors of Nurses Caring the COVID-19 Patients","authors":"Yun-Yi Yang","doi":"10.46308/kmj.2022.00192","DOIUrl":"https://doi.org/10.46308/kmj.2022.00192","url":null,"abstract":"of","PeriodicalId":166951,"journal":{"name":"Keimyung Medical Journal","volume":"147 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-12-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"129104453","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Jun Seog Lee, Yo-Han Seo, Won Yeong Jo, T. Ryu, So Young Lee, Jin Yong Jung
{"title":"Prolotherapy with Very Fine Needle and Low Concentration of Glucose in a Patient with Chronic Lateral Elbow Pain","authors":"Jun Seog Lee, Yo-Han Seo, Won Yeong Jo, T. Ryu, So Young Lee, Jin Yong Jung","doi":"10.46308/kmj.2022.00129","DOIUrl":"https://doi.org/10.46308/kmj.2022.00129","url":null,"abstract":"","PeriodicalId":166951,"journal":{"name":"Keimyung Medical Journal","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-12-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"130349659","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Jong Hae Kim, E. Choi, H. Lim, So Young Lee, Jung-A. Lim
{"title":"Ultrasound Guided Supraclavicular Brachial Plexus Block for Humerus Fracture in a Patient with Eisenmenger Syndrome","authors":"Jong Hae Kim, E. Choi, H. Lim, So Young Lee, Jung-A. Lim","doi":"10.46308/kmj.2022.00115","DOIUrl":"https://doi.org/10.46308/kmj.2022.00115","url":null,"abstract":"Eisenmenger syndrome is a pulmonary vascular disease in which pulmonary-sys-temic circulation is connected due to bidirectional shunt caused by congenital heart disease, leading to increased pulmonary vascular resistance and right ventricular failure. Intraoperative management is a challenging task for anesthesiologists when patients with Eisenmenger syndrome undergo non-cardiac surgery, and maintaining both systemic vascular resistance and pulmonary vascular resistance during surgery is critical. In this case, we report that a patient with Eisenmenger syndrome with a humerus fracture successfully underwent open reduction with internal fixation by performing ultrasound guided supraclavicular brachial plexus block and was discharged without complications. When upper limb surgery is performed in patients with Eisenmenger syndrome, ultrasound guided supraclavicular brachial plexus block has fewer hemodynamic changes such as decreased systemic venous resistance and increased pulmonary vascular resistance compared to general anesthesia, and could be a safe anesthetic method in terms of postoperative pain control.","PeriodicalId":166951,"journal":{"name":"Keimyung Medical Journal","volume":"46 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-11-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"133489749","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Updates on Intra-articular Corticosteroid Injection for the Treatment of Adhesive Capsulitis","authors":"J. Oh, I. Jung, Eun-Woo Park, J. Cho","doi":"10.46308/kmj.2022.00108","DOIUrl":"https://doi.org/10.46308/kmj.2022.00108","url":null,"abstract":"is a common disorder characterized by a gradual increase of pain and limitation in range of motion of the shoulder joint. The pathophysiological process involves fibrous inflammation of the capsule leading to capsular thickening and contracture. Intra-articular corticosteroid injection is com-monly performed in patients with adhesive capsulitis. However, there is no consensus as to the best injection site. Corticosteroid injection sites for the treatment in-clude posterior capsule approach, rotator interval approach, multi-site, and subacromial injection. All injection methods lead to improvement in adhesive capsulitis cases. In this review article, we provide an overview of current corticosteroid injection methods for adhesive capsulitis.","PeriodicalId":166951,"journal":{"name":"Keimyung Medical Journal","volume":"30 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-09-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"124966995","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Comparison of COVID-19 between Korea and Japan","authors":"S. Kim, S. Kim","doi":"10.46308/kmj.2022.00094","DOIUrl":"https://doi.org/10.46308/kmj.2022.00094","url":null,"abstract":"The incidence of COVID-19 infection between Korea and Japan,was compared focusing on three periods covering 2020.1~2021.10, 2021.11~2021.12, and 2022.1~2022.4. Between 2020.1 and 2021.10, by population, the incidence of COVID-19 infection in Korea had always been lower than in Japan and was called “Korean protection”, its contributing factors being as follows: 1. learning from the experience of Middle East Re-spiratory Syndrome, 2. thorough PCR examinations, 3. comprehensive triage policy, 4. efforts of medical staff, 5. cooperation between the citizens and government. In Korea between 2021.11 and 2021.12, the number of newly infected cases, hospitalized cases, and deaths per week increased 3.5-, 2.6-, and 4.8-fold, respectively, compared with October cases. The main reason for this increase was attributed to the so-called “with corona” policy adopted by the Korean government during the same period. In contrast, during the same period, the number of newly infected cases per day dropped dramatically to less than 1,000 in Japan, attributed to the high rate of vaccination implementation and adherence to social restrictions. Between 2022.1 and 2022.4, the Omicron variant (BA1 and BA2) of COVID-19 became prevalent in both countries. Especially, since March 12, an infection explosion occurred in Korea with over 300,000 people re-corded consecutively every day. During the same period, in Japan, the number of newly infected cases remained at less than one hundred thousand. Intercommunication is needed between the two countries to attain COVID-19 containment.","PeriodicalId":166951,"journal":{"name":"Keimyung Medical Journal","volume":"14 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-06-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"126401643","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"A Study on the Value, Current Status, and Education Direction of Medical Humanities Education in Korea","authors":"Seon-Kyoung Kim, Jun Kim, Jae-Ho Lee, J. Bae","doi":"10.46308/kmj.2022.00101","DOIUrl":"https://doi.org/10.46308/kmj.2022.00101","url":null,"abstract":"The purpose of this study is to verify the pedagogical necessity of the medical humanities and to analyze the educational contents of medical humanities in medical schools of Korea. Medical humanities education should reflect the students’ real life situations and attitudes because the educational goal of medical school students is to live as happy persons and good doctors. Understanding the medical humanities education that can achieve this goal will enable students to overcome various difficul-ties they will face in the future, and these contents should be included in graduation outcomes. The curriculum of medical humanities in Keimyung University School of Medicine was also analyzed, and based on this, we suggest the direction of education to be pursued. According to the analyzed data, medical humanities should be avoid-ed from knowledge-oriented memorization education, and the curriculum should be supplemented by finding ways to integrate with basic and clinical medicine subjects. In addition, education that can increase resilience and form the identity of a doctor who can love and care for oneself is required even in difficult situations. Many attention and research will be needed in the future to achieve the original purpose of medical humanities education to understand others and society and to rec-ognize the value of empathy and consideration.","PeriodicalId":166951,"journal":{"name":"Keimyung Medical Journal","volume":"17 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-06-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"122750442","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Predictive Factors for Sexual Behaviors among High School Students in South Korea: a Nationwide Analysis","authors":"S. Hong, Jae Hyuck Lee, Y. Suh, D. Kim","doi":"10.46308/kmj.2022.00087","DOIUrl":"https://doi.org/10.46308/kmj.2022.00087","url":null,"abstract":"We aimed to investigate the associated factors for sexual intercourse among high school students using data from the Korea Youth Risk Behavior Web-based Survey (KYRBWS) conducted between August and October 2020. This study was based on the 16th KYRBWS, conducted by the Korea Centers for Disease Control and Pre-vention. A total of 25,592 high school students were included. The questionnaire included topics such as sexual behavior, alcohol consumption, smoking, drug use, mental health, physical activity, weight management, and health equity, to determine the factors influencing sexual behavior. In male students, the associated factors for sexual behavior included smoking, alcohol consumption, history of drug use, short sleep time, high physical activity, feelings of sadness, and good economic status. In female students, the associated factors for sexual behavior included smoking, alcohol consumption, low body mass index, high physical activity, feelings of sadness, suicidal thoughts, and poor economic status. In both male and female high school students, smoking and alcohol consumption were strong associated factors for sexual behavior. Good economic status was associated with sexual behavior in males, while a poor economic condition was associated with sexual behavior in females. These factors should be considered in the sexual education of high school students.","PeriodicalId":166951,"journal":{"name":"Keimyung Medical Journal","volume":"6 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-06-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"128338447","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"The Growth Inhibitory Effect on B16F10 Melanoma Cells by 4-BPCA, an Amide Derivative of Caffeic Acid","authors":"Yu-Kyoung Park, S. Kang, Jinho Lee, B. Jang","doi":"10.46308/kmj.2022.00066","DOIUrl":"https://doi.org/10.46308/kmj.2022.00066","url":null,"abstract":"Caffeic acid (CA) is a phenolic compound found naturally in plants and foods. CA and its natural derivatives are reported to have anti-cancer effects on many cancers, including melanoma. (E)-N-(4-Butylphenyl)-3-(3,4-dihydroxyphenyl)acrylamide (4-BPCA) is an amide derivative of CA. Thus far, the anti-cancer effect and mechanism of 4-BPCA in melanoma cells remain unknown. Here we investigated whether 4-BPCA inhibits the growth of B16F10 cells, a mouse melanoma cell line. Of note, treatment of 4-BPCA at 5 µM for 24 or 48 h significantly reduced the growth (sur-vival) of B16F10 cells. On mechanistic levels, treatment with 4-BPCA for 24 h led to the activation of caspase-9/3, but not caspase-8, in B16F10 cells. 4-BPCA treatment for 2 or 4 h also decreased the expression levels of myeloid B-cell lymphoma 1 (Mcl-1) in B16F10 cells. However, 4-BPCA treatment for the times tested did not influence the expression levels of X-linked inhibitor of apoptosis protein (XIAP) in B16F10 cells. Of interest, treatment of 4-BPCA for 2 or 4 h greatly reduced the phosphorylation levels of JAK-2 and STAT-5 without altering their total protein expression levels. 4-BPCA also had abilities to increase the expression and phosphorylation levels of glucose-regulated protein-78 (GRP-78) and eukaryotic translation initiation factor-2α (eIF-2α) in B16F10 cells. In summary, these results demonstrate firstly that 4-BPCA has a strong growth-inhibitory effect on B16F10 melanoma cells, mediated via activation of the intrinsic caspase pathway, inhibition of JAK-2 and STAT-5, and triggering endoplasmic reticulum (ER) stress. cells were treated with 4-BPCA or vehicle control (DMSO; 0.1%) at the designated concentrations for 24 and 48 h, respectively. The numbers of surviving B16F10 melanoma cells were measured by cell count assay (B). Cell count assay was performed in triplicate. Data are means SE of three independent experiments. p","PeriodicalId":166951,"journal":{"name":"Keimyung Medical Journal","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-06-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"130245640","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Semin Cho, J. Paek, W. Park, K. Jin, D. K. Kim, Seungyeup Han, Yaerim Kim
{"title":"Clinical Implication of Tolvaptan in Patients with Autosomal Dominant Polycystic Kidney Disease","authors":"Semin Cho, J. Paek, W. Park, K. Jin, D. K. Kim, Seungyeup Han, Yaerim Kim","doi":"10.46308/kmj.2022.00059","DOIUrl":"https://doi.org/10.46308/kmj.2022.00059","url":null,"abstract":"Autosomal dominant polycystic kidney disease (ADPKD) is the most common genetic kidney disease characterized by the growth of numerous fluid-filled cysts in the kidneys. It leads to progressive kidney enlargement and end-stage kidney disease (ESKD) [1,2]. ADPKD is a ciliopathy that involves abnormal cilia structure and function [3]. There are polycystin-1 and polycystin-2 in the kidney tubular cell protruding primary cilium. It has a role in detecting fluid flow and regulating calcium influx that activates an intracellular calcium signaling pathway [4]. In addition, increased levels of arginine vasopressin levels induced increased intracellular adenosine cyclic monophosphate (cAMP) levels in the distal tubule and collecting duct. Tolvaptan is a vasopressin receptor antagonist; it selectively blocks the binding of V2 receptors in tubular cells and reduces fluid secretion, cell proliferation, and cyst development by reducing cAMP [5]. Tolvaptan in ADPKD papISSN 2092-8335 · eISSN 2733-5380 Keimyung Med J [Epub ahead of print] https://doi.org/10.46308/kmj.2022.00059 Original Article","PeriodicalId":166951,"journal":{"name":"Keimyung Medical Journal","volume":"58 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-06-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"133716277","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}