Journal of Pakistan Medical Association最新文献_第9页

Evaluation of serum resistin levels in Iraqi rheumatoid arthritis patients under biological treatment and their correlated clinical disease activity index 伊拉克类风湿关节炎生物治疗患者血清抵抗素水平及其相关临床疾病活动性指标的评价

Journal of Pakistan Medical Association Pub Date : 2023-10-06 DOI: 10.47391/jpma.iq-23

None Shatha Sabah Shyaa, None Hanaa Naji Abdullah, None Khaled Yassin Zakair

{"title":"Evaluation of serum resistin levels in Iraqi rheumatoid arthritis patients under biological treatment and their correlated clinical disease activity index","authors":"None Shatha Sabah Shyaa, None Hanaa Naji Abdullah, None Khaled Yassin Zakair","doi":"10.47391/jpma.iq-23","DOIUrl":"https://doi.org/10.47391/jpma.iq-23","url":null,"abstract":"Objective: The current study aimed to evaluate RA patients’ serum resistin levels and to observe the relationshipbetween disease activity and resistin.Methods: A case-control study was conducted on (100) RA Iraqi patients during treatment with bDMARDs. The firstgroup of 50 patients received etanercept, and the second group of 50 patients were on Rituximab (RTX). The controlgroup comprised of 50 healthy individuals. ELISA was used to evaluate serum Resistin in and anti-CRP. Inflammatorymarkers ESR, and CRP with biochemical tests were conducted. In addition to estimating Clinical Disease Activity scoreI(CDAI) by the physicians; at Baghdad Teaching Hospital.Results: Levels of Resistin of RA treated with RTX were significantly higher (16.30 ± 7.38ng/ml) than in RA treated withETN (10.61±5.85ng/ml) compared to the control group. (6.95±1.70 ng/ml). The resistin level showed a positivecorrelation with Anti-CCP abs which was considered to have a high positive correlation (p< 0.01) in ETN group. Whilethis correlation was lower than the RTX group, the, correlation between resistin, and ESR was the highest in RTX groupwhilst no such correlation was observed in the ETN group. There was a positive correlation with CDAI of RA subgroups(moderate activity (p<0.05), and high activity (p<0.001). The logistic regression of resistin was associated with biologicaltreatment, odds ratio was (OR=1.138, p-value= 0.014, 95% CI.1.025-1.257) during ETN, and RTX independent of CRP.Conclusion: There is an association between serum RSN and anti CRP as a result of disease activity independent ofCRP. resist in levels can be used to determine disease activity to avoid disease progression and erosion.Keywords: Protein, Antibodies, Etanercept, Rituximab, Disease, Physicians","PeriodicalId":16673,"journal":{"name":"Journal of Pakistan Medical Association","volume":"57 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-10-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"134943853","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The effectiveness of eucalyptus globulus and thymus vulgaris in reducing COVID-19 symptoms among COVID-19 patients at Al- Nasiriya City 巨桉和寻常胸腺对减轻纳西里耶市COVID-19患者症状的效果

Journal of Pakistan Medical Association Pub Date : 2023-10-06 DOI: 10.47391/jpma.iq-16

None Rawaa Kamel Abd, None Duaa Abd Al Azem, None Ayad Abbas Aend, None Khalied Yassen Zakair

{"title":"The effectiveness of eucalyptus globulus and thymus vulgaris in reducing COVID-19 symptoms among COVID-19 patients at Al- Nasiriya City","authors":"None Rawaa Kamel Abd, None Duaa Abd Al Azem, None Ayad Abbas Aend, None Khalied Yassen Zakair","doi":"10.47391/jpma.iq-16","DOIUrl":"https://doi.org/10.47391/jpma.iq-16","url":null,"abstract":"Objective: To determine how Thymus vulgaris and Ecalyptus globulus affected the symptoms of coronavirus disease-2019 patients.Method: The experimental case-control study was conducted in Al-Nasiriya city, Iraq, from December 15, 2020, toFebruary 20, 2021, and comprised patients of either gender aged 20-50 years diagnosed with coronavirus disease-2019 infection. The patients’ symptoms ranged from mild to severe. Half of the sample was exposed to the study’streatment protocol, while the other half acted as control. Thyme, orange and lemon were employed as sources ofvitamin C, as well as eucalyptus leaves and oil. The cases were exposed to eucalyptus vapours for 5-10 minutes afterthoroughly washing the plant leaves (7-10 leaves or 5 drops of oil) and boiling them in drinking water at 100°C for 10-15 minutes. Data was analysed using SPSS 23.Results: Of the 48 patients, 24(50%) were in each of the two groups. Age and gender were not significantly different(p>0.05), while body mass index and blood group distribution was significantly different between the groups (p<0.05).Overall, 22(45.8%) subjects had mild symptoms, 20(41.7%) had moderate symptoms and 6(12.5%) had severesymptoms. The improvement in the symptoms among the cases was significantly more than the controls (p<0.05)except nasal congestion (p>0.05).Conclusion: Using eucalyptus vapours in the form of dried leaves or oil could significantly lessen coronavirus disease-2019 symptoms.Keywords: Eucalyptus, Thymus, Plant, Citrus, Cough, Smell, COVID-19, Leaves, Vaccines, Vitamins.","PeriodicalId":16673,"journal":{"name":"Journal of Pakistan Medical Association","volume":"26 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-10-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"134944234","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Red eyes: COVID-19 or Microbial infection 眼睛发红:COVID-19或微生物感染

Journal of Pakistan Medical Association Pub Date : 2023-10-06 DOI: 10.47391/jpma.iq-10

None Hussein Katai Abdul Sada, None Salah Zuhair Abed Al Asadi, None Ahmed Mohammed Alsamak, None Amaleed Abduljaleel Alkadhem

{"title":"Red eyes: COVID-19 or Microbial infection","authors":"None Hussein Katai Abdul Sada, None Salah Zuhair Abed Al Asadi, None Ahmed Mohammed Alsamak, None Amaleed Abduljaleel Alkadhem","doi":"10.47391/jpma.iq-10","DOIUrl":"https://doi.org/10.47391/jpma.iq-10","url":null,"abstract":"Objective: To identify the source of eyes infections during coronavirus disease-2019 pandemic.Method: The cross-sectional study was conducted at the Al-Basrah Teaching Hospital, Iraq from March 2 to September24, 2020, and comprised eye swabs from patients having confirmed diagnosis of coronavirus disease-2019. The swabswere subjected to microbiological and molecular examinations. They were cultivated on blood agar and savoureddextrose agar plates to detect the types of microbes and then confirmed by genetic analysis using polymerase chainreaction. Chi-square was used to identify the differences between samples who had symptoms or those who had nosymptoms p Less than or Equal to 0.05 was considered significant.Results: Of the 213 patients quarantined with coronavirus disease-2019, there were 98(46%) males and 115(54%)females. Of them, 22(10.3%) had red eyes; 10(45.45%) males and 12(54.54%) females, with overall age ranging 18-74years. Streptococcus pneumonia was detected in 8(36.6%) patients, followed by staphylococcus aureus and candidaalbicans 5(22.7%) each, and haemophilus influenzae 3(13.6%).Conclusion: Red eyes of some patients with coronavirus disease-2019 may have been caused by secondary infection.Keywords: Agar, Staphylococcus aureus, Photophobia, Polymerase chain reaction, Glucose, Pruritus.","PeriodicalId":16673,"journal":{"name":"Journal of Pakistan Medical Association","volume":"4 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-10-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"134944631","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Correlation between Neutrophil gelatinase-associated lipocalin and ß2-Microglobulin with serum protein electrophoresis in multiple myeloma patients 多发性骨髓瘤患者中性粒细胞明胶酶相关脂钙蛋白和ß - 2微球蛋白与血清蛋白电泳的相关性

Journal of Pakistan Medical Association Pub Date : 2023-10-06 DOI: 10.47391/jpma.iq-01

None Inas Nazeeh Abed, None Hiba Abid Al-Hussein Hassan, None Usama Salman Al Timari

{"title":"Correlation between Neutrophil gelatinase-associated lipocalin and ß2-Microglobulin with serum protein electrophoresis in multiple myeloma patients","authors":"None Inas Nazeeh Abed, None Hiba Abid Al-Hussein Hassan, None Usama Salman Al Timari","doi":"10.47391/jpma.iq-01","DOIUrl":"https://doi.org/10.47391/jpma.iq-01","url":null,"abstract":"Objective: To find the correlation between neutrophil gelatinase-associated lipocalin and beta2-microglobulin inpatients with multiple myeloma.Method: The case-control study was conducted from November 2021 to March 2022, after approval from ethics reviewcommittees of three major medical establishments in Baghdad, Iraq. There were randomly selected multiple myelomapatients of either gender with normal concentration of urea and creatinine in group A, multiple myeloma patients ofeither gender with increased concentration of urea and creatinine in group B and healthy controls in group C.Neutrophil gelatinase-associated lipocalin and beta2-microglobulin were assessed using enzyme-linkedimmunosorbent assay technique. Data was analysed using SPSS 26.Results: Of the 180 subjects, there were 60(33.3%) in each of the 3 groups, with each group having 40(66.5%) malesand 20(33.3%) females, and overall age ranging 40-79 years. Protein electrophoresis in group A patients wassignificantly higher (p=0.001) in alpha1, beta and gamma globulin. Among group B patients, a highly significantincrease (p=0.001) was noted in alpha1, alpha2, beta and gamma globulin. Beta2-microglobulin was a more sensitiveand specific marker for renal injury than neutrophil gelatinase-associated lipocalin in myeloma patients(p<0.05).Conclusion: Beta2-microglobulin and neutrophil gelatinase-associated lipocalin were both more sensitive markersthan serum urea and creatinine in the diagnosis of acute kidney injury in multiple myeloma patients.Keywords: Lipocalin, Creatinine, Multiple myeloma, Microglobulin, Urea, Electrophoresis, Globulins, Albumins,Enzyme, Immunosorbent assay, Kidney injury.","PeriodicalId":16673,"journal":{"name":"Journal of Pakistan Medical Association","volume":"52 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-10-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"134943983","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The effect of letrozole treatment on the fertility and embryos parameters in female mice: Histological and hormonal study 来曲唑对雌性小鼠生育能力和胚胎参数的影响:组织学和激素研究

Journal of Pakistan Medical Association Pub Date : 2023-10-06 DOI: 10.47391/jpma.iq-31

None Sally Adnan Mousa AL Rekabi, None Noor Noori Abid Al Shemary

{"title":"The effect of letrozole treatment on the fertility and embryos parameters in female mice: Histological and hormonal study","authors":"None Sally Adnan Mousa AL Rekabi, None Noor Noori Abid Al Shemary","doi":"10.47391/jpma.iq-31","DOIUrl":"https://doi.org/10.47391/jpma.iq-31","url":null,"abstract":"Objective: To evaluate how letrozole affects reproductive hormones and embryos in mature female mice.Method: The investigative study was conducted from December 2021 to February 2022 at the Pathology Departmentof Kut Technical Institute, Al-Kut, Iraq, and comprised adult female albino mice weighing 23-25g. The mice were dividedinto control group A, those receiving 1.5mg/kg/day letrozole in group B, and those receiving 2.5mg/kg/day letrozolein group C. The intervention lasted 14 days. Blood samples were collected under anaesthesia by heart puncture forhormonal testing. Data was analysed using SPSS 15.Results: Of the 30 mice, 10(33.3%) were in each of the 3 groups. Right and left ovaries of mice in groups B and Cshowed a significant rise in multi-follicular cells compared to group A (p<0.05). Follicle-stimulating hormone, oestrogenand progesterone concentrations as well as luteinizing hormone increased significantly in the intervention groupscompared to the control group (p<0.05). The impact of letrozole on embryos was significant in groups B and Ccompared to group A.Conclusions: Letrozole was found to have a positive effect on reproductive parameters and hormones in mice.Keywords: Mice, Ovary, Letrozole, oestrogen, Progesterone, Luteinizing hormone.","PeriodicalId":16673,"journal":{"name":"Journal of Pakistan Medical Association","volume":"8 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-10-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"134944096","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Sero-prevalence of Hepatitis C virus infection in patients undergoing haemodialysis in Al-Najaf Province 纳杰夫省血液透析患者丙型肝炎病毒感染的血清流行率

Journal of Pakistan Medical Association Pub Date : 2023-10-06 DOI: 10.47391/jpma.iq-34

None Khalida Abbas Al Kelaby, None Qabas Neamah Hadi Al Hajjar, None Ghaith Kadhim Al Azam

引用次数: 0

Workplace stress among healthcare workers in Kut city, Iraq, 2020 2020年，伊拉克库特市医护人员的工作压力

Journal of Pakistan Medical Association Pub Date : 2023-10-06 DOI: 10.47391/jpma.iq-09

None Fatima Haran Deham, None Alaa Kadhim Jasim, None Khalied Yassen Zakair

引用次数: 0

Relationship between social support and self-hardiness among breast cancer women in Nasiriyah, Iraq 伊拉克纳西里耶乳腺癌妇女的社会支持与自我适应能力的关系

Journal of Pakistan Medical Association Pub Date : 2023-10-06 DOI: 10.47391/jpma.iq-02

None Gossoon Juma Elywy, None Mohammed Malih Radhi, None Qasim Abbas Khyoosh AlEqabi

{"title":"Relationship between social support and self-hardiness among breast cancer women in Nasiriyah, Iraq","authors":"None Gossoon Juma Elywy, None Mohammed Malih Radhi, None Qasim Abbas Khyoosh AlEqabi","doi":"10.47391/jpma.iq-02","DOIUrl":"https://doi.org/10.47391/jpma.iq-02","url":null,"abstract":"Objective: To assess the role of social support in predicting self-hardiness among women having breast cancer.Method: The descriptive correlational study was conducted at the Oncology Centre, Nasiriyah, Iraq, from August 3 toSeptember 22, 2022, and comprised women receiving treatment for breast cancer. Data was collected using a questionnairedesigned in the light of the Multidimensional Scale of Perceived Social Support, which was found reliable on the basis of apilot study. Data was analysed using SPSS 20.Results: There were 150 women with mean age 50.4±11.18 years. Of them, 135(90%) were married, 113(75.3%) wereunemployed, 90(60%) were living in rural areas, and 89(59.3%) had low socioeconomic status. Overall, 108(72%) patientsreported they received little social support. Self-hardiness significantly differed in relation to marital status (p=0.021), placeof residence (p=0.003) and income level (p=0.005). Social support positively correlated with self-hardiness (p=0 .000).Conclusion: Social support was found to be a predictor of increased self-hardiness that enhances resilience and enablespatients to deal with one of the most devastating illnesses of modern times.Keywords: Cancer, Breast, Neoplasms, Counselling.","PeriodicalId":16673,"journal":{"name":"Journal of Pakistan Medical Association","volume":"4 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-10-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"134943844","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Molecular detection of virulence genes in pseudomonas aeruginosa isolated from different clinical infections 不同临床感染源铜绿假单胞菌毒力基因的分子检测

Journal of Pakistan Medical Association Pub Date : 2023-10-06 DOI: 10.47391/jpma.iq-13

None Enass Abdul Kadhum Almkhadhree, None Kawther Adnan Alqaseer, None Khairi Jameel AL Ruaby

{"title":"Molecular detection of virulence genes in pseudomonas aeruginosa isolated from different clinical infections","authors":"None Enass Abdul Kadhum Almkhadhree, None Kawther Adnan Alqaseer, None Khairi Jameel AL Ruaby","doi":"10.47391/jpma.iq-13","DOIUrl":"https://doi.org/10.47391/jpma.iq-13","url":null,"abstract":"Objective: To isolate pseudomonas aeruginosa from different clinical specimens, and to detect virulence factors.Method: The cross-sectional study was conducted at Al-Zharr Hospital and private clinics in Kut city of Wasit provincein Iraq from October 15, 2021, to April 30, 2022, and comprised samples obtained from different patient sites, such aswound swabs, ear swabs, urine samples, burn swabs and respiratory tract swabs. The samples were subjected tomolecular testing using, among other tools, polymerase chain reaction. The isolates were cultured on different media,such as blood agar, MacConkey agar and cetrimide agar, and were further diagnosed by biochemical testing. Datawas analysed using SPSS 20.Results:Of the 212 samples, there were 70(33%) wound swabs, 53(25%) ear swabs, 41(19.3%) urine samples, 33(15.6%)burn swabs and 15(7%) respiratory tract swabs. Pseudomonas aeruginosa was identified in 54(25.47%) isolates viaculture-based characterisation. All 54(100%) isolates were positive for mexR and toxA on polymerase chain reaction,44(81.48%) were positive for exoU gene, 43(79.62%) for exoT gene, 36 (66.66) for exoT gen, 35(64.81%) for plcH, geneand 14(25.92 %) for exoS gene.Conclusions: Wound swabs were found to be the most common site for pseudomonas aeruginosa, followed by earswabs and urine samples.Keywords: Pseudomonas aeruginosa, Virulence, Agar, Cetrimonium, Virulence, Burns, Polymerase chain reaction, DNA.","PeriodicalId":16673,"journal":{"name":"Journal of Pakistan Medical Association","volume":"159 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-10-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"134944351","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Knowledge, attitude and practice of nursing staff regarding hepatitis B at Kut city, middle Iraq 伊拉克中部库特市护理人员对乙型肝炎的知识、态度和做法

Journal of Pakistan Medical Association Pub Date : 2023-10-06 DOI: 10.47391/jpma.iq-33

None Rawaa Kamel Abd, None Basim Rihan Sahar

{"title":"Knowledge, attitude and practice of nursing staff regarding hepatitis B at Kut city, middle Iraq","authors":"None Rawaa Kamel Abd, None Basim Rihan Sahar","doi":"10.47391/jpma.iq-33","DOIUrl":"https://doi.org/10.47391/jpma.iq-33","url":null,"abstract":"Objective: To assess the level of knowledge, attitude and practice of nursing staff towards hepatitis B virus infection.Method: The cross-sectional study was conducted at three hospitals in Kut, Iraq, in July 2020, and comprised nursingstaff regardless of age and gender. Data was collected using a predesigned questionnaire exploring demographicdetails as well as knowledge, attitude and practice of the nursing staff regarding hepatitis B virus infection. Data wasanalysed using SPSS 21.Result: Of the 3,008 nurses, 341(11.33%) were randomly enrolled; 170(49.9%) males and 171(50.1%) females. Therewere 140(41.1%) subjects aged 20–30 years, while 16(4.7%) were aged Greater than or Equal to 50 years. The mean knowledge score was 22.22±2.79 (range: 18-35 years), indicating better knowledge. The mean attitude score was 19.23±2.74 (range: 11-26), indicating positive attitude. The mean practice score was 13.04±1.84 (range: 8-17) indicating good practices.Conclusion: The knowledge level related to hepatitis B virus among the nursing staff was good. Overall improvementrelated to knowledge, attitude and practice among the nursing staff was needed.Keywords: Hepatitis, Virus, Health, Studies, Nurses, Surveys.","PeriodicalId":16673,"journal":{"name":"Journal of Pakistan Medical Association","volume":"300 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-10-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"134944509","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0