Journal of Parathyroid Disease最新文献_第7页

Defining vitamin D deficiency in patients with sickle cell disease; A meta-analysis 镰状细胞病患者维生素D缺乏症的定义一个荟萃分析

Journal of Parathyroid Disease Pub Date : 2022-10-19 DOI: 10.34172/jpd.2022.11154

Anupama Sahu, Udit Narayan Padhi, L. Bhaskar

{"title":"Defining vitamin D deficiency in patients with sickle cell disease; A meta-analysis","authors":"Anupama Sahu, Udit Narayan Padhi, L. Bhaskar","doi":"10.34172/jpd.2022.11154","DOIUrl":"https://doi.org/10.34172/jpd.2022.11154","url":null,"abstract":"Introduction: Sickle cell disease (SCD) is one of the hereditary blood disorders that affects the red blood cells. Several lines of evidence indicated that the vitamin D deficiency (VDD) is quite common in children with SCD and vitamin D supplementation enhanced health-related quality of life in these patients. The present study is aimed to assess the exact prevalence of VDD in SCD patients using meta-analysis. Materials and Methods: A systematic search was conducted in PubMed and Google Scholar to extract the papers that contain prevalence data and numbers of patients with VDD in SCD patients and healthy people. Pooled prevalence was estimated using MAJOR module of Jamovi library. The overall risk ratio of having VDD in patients with SCD was calculated using the Review Manager (RevMan 5.4.1) program. Results: A total of 26 prevalence estimates from 25 papers were included in the meta-analysis. The pooled prevalence of VDD among SCD patients is 60% (95% CIs: 50%-70%). Further, VDD is not significantly different in both SCD patients and healthy controls (risk ratio of 1.28 and 95% CI of 0.81-2.04). Conclusion: Results of this meta-analysis indicate prevalence of VDD in SCD patients. Further, a well-designed, placebo-controlled RCTs have to be conducted to determine the effects and the safety of vitamin D supplementation in children and adults with SCD.","PeriodicalId":16657,"journal":{"name":"Journal of Parathyroid Disease","volume":"46 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-10-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"79809590","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

Aliskiren in the treatment of renal disease; a narrative review 阿力克连治疗肾脏疾病;叙述性回顾

Journal of Parathyroid Disease Pub Date : 2022-10-19 DOI: 10.34172/jpd.2022.11164

B. Roshan, Tella Sadighpour

{"title":"Aliskiren in the treatment of renal disease; a narrative review","authors":"B. Roshan, Tella Sadighpour","doi":"10.34172/jpd.2022.11164","DOIUrl":"https://doi.org/10.34172/jpd.2022.11164","url":null,"abstract":"The renin–angiotensin–aldosterone system (RAAS) cascade has a significant effect on several systems. Angiotensin II (AngII) has appeared as not only a vasoactive peptide but also as a multifunctional cytokine that displays several non-hemodynamic properties beyond renal hemodynamic properties. The kidney includes total components of the RAAS such as aldosterone and AngII not only adjust renal hemodynamics and reabsorption of sodium but also activating various inflammatory and fibrotic responses. Inhibition of the RAAS is one of the most potent methods to impede the development of renal diseases such as chronic kidney disease (CKD) and its related problems such as high blood pressure and heart disorders. Aliskiren, an octanamide, nonpeptide piperidine, orally, active, first commercially available, and direct renin inhibitor (DRI), impedes RAAS and operates by attaching to the active sites of renin and may be effective for the management of renal disease because of blocking the RAAS at its point of start and most sensitive step. Based on numerous studies, aliskiren is the greatest powerful inhibitor of AngII extents among RAAS inhibitors, even though it is unable to prevent the (pro) renin receptor-mediated extracellular signal-regulated kinase 1 and 2 (ERK1/2) activations. In this review, it is described renoprotective effects of aliskiren against different types of nephropathy such as acute kidney injury, diabetic nephropathy, and hypertensive nephropathy.","PeriodicalId":16657,"journal":{"name":"Journal of Parathyroid Disease","volume":"66 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-10-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"91375175","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The incidence of congenital hypothyroidism in neonates born in Chaharmahal and Bakhtiari province from 2015 to 2021; A cross-sectional study 2015 - 2021年查哈尔马哈尔省和巴赫蒂亚里省新生儿先天性甲状腺功能减退发病率分析横断面研究

Journal of Parathyroid Disease Pub Date : 2022-10-18 DOI: 10.34172/jpd.2022.10157

Yasaman Koohshoori, Mohammad Moein Derakhshan Barjoei, Reyhane Izadi, S. Pourrezaei, M. Mousavi

{"title":"The incidence of congenital hypothyroidism in neonates born in Chaharmahal and Bakhtiari province from 2015 to 2021; A cross-sectional study","authors":"Yasaman Koohshoori, Mohammad Moein Derakhshan Barjoei, Reyhane Izadi, S. Pourrezaei, M. Mousavi","doi":"10.34172/jpd.2022.10157","DOIUrl":"https://doi.org/10.34172/jpd.2022.10157","url":null,"abstract":"Introduction: Congenital hypothyroidism (CH) is one of the most common endocrine and metabolic disorders and a common preventable cause of mental retardation across the world. This disorder can be prevented if diagnosed and treated before the age of four weeks. Objectives: This study was performed to investigate the incidence rate of CH in infants in Chaharmahal and Bakhtiari province. Patients and Methods: The data of this study were obtained by the CH screening program from 2015 to 2021 in the health deputy of Chaharmahal and Bakhtiari province. Results: A total of 651 patients were diagnosed with CH, which showed an incidence rate of 5.06 per 1000 births (1 per 198 live births) in the province. The highest incidence of the disease was obtained in 2016 and the lowest incidence in 2021. Lordegan city had the highest incidence rate (8.1 per 1000 live births) and Kiar had the lowest one (1.67 per 1000 live births) during the study period. Moreover, the highest and lowest incidence rates in terms of season were observed in winter and summer, respectively. Conclusion: It can be concluded that Chaharmahal and Bakhtiari province, especially Lordegan, is one of the regions with high prevalence of CH in Iran, therefore the incidence rate is not only higher than the national average but also higher than the global average. Hence, the potential causes of this observation deserve further investigation.","PeriodicalId":16657,"journal":{"name":"Journal of Parathyroid Disease","volume":"18 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-10-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"90438785","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Middle East pain syndrome as a mixture of various chronic diseases 中东疼痛综合征是多种慢性疾病的混合体

Journal of Parathyroid Disease Pub Date : 2022-10-08 DOI: 10.34172/jpd.2022.10153

Mahsa Rafieian, H. Mardanparvar, Yassamin Rabiei, H. Nasri

引用次数: 0

Comparison of care burden of hemodialysis and kidney transplant patients 血液透析与肾移植患者护理负担的比较

Journal of Parathyroid Disease Pub Date : 2022-10-08 DOI: 10.34172/jpd.2022.10151

İdris Yıldız, Mehtap Kavurmacı

{"title":"Comparison of care burden of hemodialysis and kidney transplant patients","authors":"İdris Yıldız, Mehtap Kavurmacı","doi":"10.34172/jpd.2022.10151","DOIUrl":"https://doi.org/10.34172/jpd.2022.10151","url":null,"abstract":"Introduction: End-stage renal disease (ESRD) is an important health problem in which chronic, inflammatory, degenerative and irreversible. Objectives: The research was conducted to compare burden of caregivers of hemodialysis (HD) and kidney transplantation (KT) patients. Patients and Methods: This descriptive study was conducted with HD, KT patients and their primary caregivers in a university hospital between July 2019 and June 2020. Power analysis was used to determine the sample size of the study, and a total of 71 HD and 71 KT patients and their caregivers (n=142) were included in the study sample at a confidence interval of 85%. The Zarit Burden Interview (ZBI) scale was used in data collection. The data were analysed by using the SPSS version 22.0 software. Results: As a result of the study, it was determined that the mean caregiver burden score (30.59±13.25) of the caregivers of HD patients was higher than the mean caregiver burden score (22.20±13.95) of the KT patients, and the difference was statistically significant. The difference between socio-demographic characteristics of the caregivers of HD patients and the mean ZBI score was not statistically significant. A statistically significant difference was detected between the age and marital status and the mean ZBI scale scores of the caregivers of patients who underwent KT. Conclusion: As a result of the study, it was found that the care burden of HD patients was higher than the care burden of KT patients. In order to provide holistic care, healthcare professionals need to address the care burden of HD patients.","PeriodicalId":16657,"journal":{"name":"Journal of Parathyroid Disease","volume":"108 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-10-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"81242272","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The therapeutic, preventive, and immune-boosting effects of some minerals and vitamins in COVID-19: A narrative review 一些矿物质和维生素在COVID-19中的治疗、预防和免疫增强作用:叙述性综述

Journal of Parathyroid Disease Pub Date : 2022-09-11 DOI: 10.34172/jpd.2022.9151

A. Hassanzadeh Rad, Amirhossein Fakhre Yaseri

引用次数: 2

Hemodynamic changes and related factors in bone cement implantation syndrome in knee arthroplasty candidates 膝关节置换术患者骨水泥植入综合征的血流动力学变化及相关因素

Journal of Parathyroid Disease Pub Date : 2022-08-27 DOI: 10.34172/jpd.2022.9146

A. Moradi, N. Abedini

{"title":"Hemodynamic changes and related factors in bone cement implantation syndrome in knee arthroplasty candidates","authors":"A. Moradi, N. Abedini","doi":"10.34172/jpd.2022.9146","DOIUrl":"https://doi.org/10.34172/jpd.2022.9146","url":null,"abstract":"Introduction: Considering the importance of the anesthesia and surgery team’s awareness of possible hemodynamic changes when using bone cement and preventing its risks, it is very important to know about this issue. Objectives: This study aimed to identify and prevent the risks of possible hemodynamic changes and related factors when using bone cement in knee arthroplasty candidates. Patient and Methods: This descriptive-analytical study of 63 knee arthroplasty candidates in Imam Reza and Shohada hospitals (affiliated with the Tabriz university of medical sciences) was conducted in 2020. The hemodynamic status (heart rate, blood pressure, and arterial oxygen saturation (SaO2 )) of all patients was recorded and changes were calculated three minutes before, during, and three minutes after using bone cement. Results: The increase in diastolic (P=0.221) and systolic (P=0.195) blood pressure and heart rate (P=0.125) over time (before and after using bone cement) was statistically insignificant. However, the arterial oxygen saturation of patients remained constant (P=0.999). Conclusion: The results showed that using bone cement causes minor changes in (systolic and diastolic) blood pressure and heart rate.","PeriodicalId":16657,"journal":{"name":"Journal of Parathyroid Disease","volume":"44 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-08-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"78549701","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

The relationship between vitamin D and calcium serum levels with dental caries in 6-12 years old children 6-12岁儿童血清维生素D和钙水平与龋病的关系

Journal of Parathyroid Disease Pub Date : 2022-08-20 DOI: 10.34172/jpd.2022.9141

L. Saboktakin

{"title":"The relationship between vitamin D and calcium serum levels with dental caries in 6-12 years old children","authors":"L. Saboktakin","doi":"10.34172/jpd.2022.9141","DOIUrl":"https://doi.org/10.34172/jpd.2022.9141","url":null,"abstract":"Introduction: There are limited studies with contradictory results on the relationship between vitamin D and calcium levels with dental caries at different ages. Objectives: Given the contradictory results of studies and the importance of preventing the onset and progression of dental caries for oral health, this study aimed to find the relationship between vitamin D and calcium levels with dental caries in 6-12 years old children. Patients and Methods: This descriptive-cross sectional study was conducted from 2019 to 2020 on 256 children of 6-12 years old referring to children’s hospital in Tabriz. Serum vitamin D (sufficient, insufficient or deficient) and calcium (sufficient, insufficient) levels were measured for each child, and the relationship between their levels and dental caries was investigated by descriptive and inferential statistical tests. Results: The dental index of decayed, missing and filled teeth (DMFT) in the deficient and insufficient vitamin D groups was significantly higher than in the sufficient vitamin D group (P=0.03). The linear regression model on the effect of age, vitamin D, and calcium on dental indexes showed no significant statistical relationship. However, in the case of the dental index, age, and calcium level affected dental caries (d), but vitamin D did not affect this index. Conclusion: There was no significant relationship between calcium and vitamin D serum levels with dental caries in 6-12 years old children.","PeriodicalId":16657,"journal":{"name":"Journal of Parathyroid Disease","volume":"23 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-08-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"80239192","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

Evaluation of radiation side effects on thyroid function 放射副反应对甲状腺功能的影响

Journal of Parathyroid Disease Pub Date : 2022-08-16 DOI: 10.34172/jpd.2022.9145

Kolsoum Teimouri, Samaneh Pakravan, Elham Rahmatinia, Kamran Azadbakht

引用次数: 0

Examining the relationship between non-alcoholic fatty liver disease and hypothyroidism 探讨非酒精性脂肪性肝病与甲状腺功能减退的关系

Journal of Parathyroid Disease Pub Date : 2022-08-16 DOI: 10.34172/jpd.2022.9148

Kolsoum Teimouri, Samaneh Pakravan, Kamran Azadbakht

引用次数: 0