Journal of Orofacial Sciences最新文献_第2页

Evaluation of Salivary Biomarker Levels in Children with Autism Spectrum Disorder Having Dental Caries 评估患有龋齿的自闭症谱系障碍儿童的唾液生物标志物水平

Journal of Orofacial Sciences Pub Date : 2023-01-01 DOI: 10.4103/jofs.jofs_96_23

Disha Sharma, S. Bhandary, V. Prabhu

{"title":"Evaluation of Salivary Biomarker Levels in Children with Autism Spectrum Disorder Having Dental Caries","authors":"Disha Sharma, S. Bhandary, V. Prabhu","doi":"10.4103/jofs.jofs_96_23","DOIUrl":"https://doi.org/10.4103/jofs.jofs_96_23","url":null,"abstract":"Introduction: Children with special health care exhibit behavioral and physical conditions that predispose them to oxidative stress and this plays a vital role in etiopathogenesis of autistic spectrum disorder (ASD), which promotes neuronal damage in genetically predisposed individuals. Any inflammatory process initiates lipid peroxidation reaction that leads to the production of malondialdehyde (MDA), which in turn alters the immunological mediators such as salivary peroxidase system. Thus, leading to initiation and progression of bacterial infections such as dental caries. Materials and Methods: Fifteen children with ASD between the age groups of 6 and 14 years, who reported to the Nitte Special Child Care Centre (N-SPECC), Department of Pediatric and Preventive Dentistry, were selected for the study. Baseline salivary samples were collected to evaluate the salivary MDA, pH, viscosity, and buffering capacity. The patients were recalled after a period of 2 months where oral health education and saliva samples were collected and evaluated for the above parameters post-treatment and the data were subjected to statistical analysis using the Shapiro-Wilk test and Wilcoxon signed-rank test. Results: There was a statistically significant difference seen for the values between the time intervals (2 months) (P < 0.01) for salivary MDA, pH, viscosity, and buffering capacity levels in children with ASD with dental caries post-treatment. Conclusion: The levels of salivary MDA, pH, and viscosity decreased significantly and furthermore, the levels of buffering capacity increased significantly post-treatment in children with ASD. Evaluation of these biomarkers can be good adjuncts in caries risk assessment in children with ASD.","PeriodicalId":16651,"journal":{"name":"Journal of Orofacial Sciences","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"47666638","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Effect of light-curing silver diamine fluoride on microtensile bond strength of primary carious dentin restored with glass ionomer cement: In vitro study 光固化氟二胺银对玻璃离子水门汀修复初级龋牙本质微拉伸粘结强度的影响

Journal of Orofacial Sciences Pub Date : 2023-01-01 DOI: 10.4103/jofs.jofs_242_22

Haradwala Zaineb, J. Winnier, Soni Arwa

{"title":"Effect of light-curing silver diamine fluoride on microtensile bond strength of primary carious dentin restored with glass ionomer cement: In vitro study","authors":"Haradwala Zaineb, J. Winnier, Soni Arwa","doi":"10.4103/jofs.jofs_242_22","DOIUrl":"https://doi.org/10.4103/jofs.jofs_242_22","url":null,"abstract":"Introduction: Silver diamine fluoride (SDF) has been used as a caries arresting agent. The application protocol of SDF is unclear. Some clinicians prefer to light cure SDF to accelerate the hardening of SDF; however, the effect of the same on bond strength of the restoration is unknown. This study aimed to determine the effect of light-curing SDF on microtensile bond strength (µTBS) of primary teeth restored with glass ionomer cement (GIC). Materials and Methods: Seventeen carious primary molars were sectioned through the middle of the carious lesion and allocated randomly to three groups. Group 1—SDF application followed by GIC restoration, group 2—SDF application followed by light cure of SDF and restored with GIC, group 3—control: GIC restoration without SDF application (n = 11). The samples were stored in artificial saliva; evaluated for µTBS under universal testing machine until failure. The failure mode was evaluated using stereomicroscope at 40× magnification. Results: µTBS of the groups were compared using Kruskal–Wallis test, which showed a statistically significant difference between the groups (P < 0.05). Dunn’s post hoc test revealed a significantly higher bond strength with group 2 (4.15 ± 2.51) compared to group 1 (1.40 ± 0.49) (P value 0.022). The failure modes for each group were carried out with chi-square test which revealed no statistically significant difference. Conclusion: Light-curing SDF prior to application of GIC resulted in significantly greater bond strength when compared to non–light-cured SDF.","PeriodicalId":16651,"journal":{"name":"Journal of Orofacial Sciences","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43473470","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Evaluation of Antimicrobial Effect of Herbal Medicaments - Mangosteen, Turmeric, Babul Extracts, and Chlorhexidine against Candida albicans Biofilm in Endodontics: An In Vitro Study 芒果苷、姜黄、巴布尔提取物和氯己定对口腔内白色念珠菌生物膜的抗菌作用评价：体外研究

Journal of Orofacial Sciences Pub Date : 2023-01-01 DOI: 10.4103/jofs.jofs_134_23

Vinoo Ramachandran, Mensudar Rathakrishnan, V. Mudimbaimannar, M. Ravindrran, Alargarsamy Venkatesh, Jayakumar Dinakar

{"title":"Evaluation of Antimicrobial Effect of Herbal Medicaments - Mangosteen, Turmeric, Babul Extracts, and Chlorhexidine against Candida albicans Biofilm in Endodontics: An In Vitro Study","authors":"Vinoo Ramachandran, Mensudar Rathakrishnan, V. Mudimbaimannar, M. Ravindrran, Alargarsamy Venkatesh, Jayakumar Dinakar","doi":"10.4103/jofs.jofs_134_23","DOIUrl":"https://doi.org/10.4103/jofs.jofs_134_23","url":null,"abstract":"Introduction: Identification of causative microorganisms in the infected root canal can help in successful treatment. Microorganisms produce a mixture of organic volatile compounds, and determining these volatile organic compound metabolites by gas chromatography/mass spectrometry (GC/MS) can help in pathogen identification in significant time by detecting the signature compounds of that particular organism. Commonly used root canal medicaments can cause a cytotoxic effect on tissue. Herbal medicaments with antimicrobial properties and less toxicity can be used as alternatives. This study aimed to evaluate in detail the metabolomes of Candida albicans and also assess the antimicrobial efficacy of herbal medicines (mangosteen, turmeric, and babul extracts) and chlorhexidine against C. albicans biofilm. Materials and methods: To examine the volatile organic compounds of C. albicans, the GC/MS method was employed. The phytochemical constituents of natural medicament extracts were identified using GC–MS analysis. Ethanol extracts of medicaments (50 mg/mL) were prepared and agar well diffusion method was used to assess the antimicrobial activity of herbal medicaments. Group 1: mangosteen extract, Group 2: babul extract, Group 3: turmeric extract, Group 4: chlorhexidine, Group 5: saline with chlorhexidine as a positive control. Results: Volatile organic compound metabolites determined by GC/MS revealed the signature volatile compounds of C. albicans. Antimicrobial evaluation by agar-well diffusion assay showed that babul exhibited the lowest zone of inhibition, whereas 2% chlorhexidine showed the highest zone of inhibition, followed by mangosteen extract. Conclusion: Due to their relative biosafety, natural plant-derived root canal medicaments can be considered as alternative options compared to synthetic medicaments.","PeriodicalId":16651,"journal":{"name":"Journal of Orofacial Sciences","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49093304","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Gray Value Evaluation of Mandibular Bone in the Adult and Elderly: Pilot Study for Osteoporosis Screening 成人和老年人下颌骨灰度值评价:骨质疏松筛查的初步研究

Journal of Orofacial Sciences Pub Date : 2023-01-01 DOI: 10.4103/jofs.jofs_262_22

Inka Saraswati, Cindy Lorenza, B. Kiswanjaya, S. Syahraini

{"title":"Gray Value Evaluation of Mandibular Bone in the Adult and Elderly: Pilot Study for Osteoporosis Screening","authors":"Inka Saraswati, Cindy Lorenza, B. Kiswanjaya, S. Syahraini","doi":"10.4103/jofs.jofs_262_22","DOIUrl":"https://doi.org/10.4103/jofs.jofs_262_22","url":null,"abstract":"Introduction: Postmenopausal women are more at risk of osteoporosis than men of the same age. Osteoporosis is often undetected due to lack of symptoms. The aim of the study was to explore the potential of gray value (GV) in clinical panoramic radiographs as a screening method for osteoporosis. Cross-sectional comparative study using secondary data. GV of mandible in panoramic radiographs between male and female of several age groups were compared. X-ray parameters were considered. Materials and Methods: A total of 294 panoramic radiographs were obtained from regular clinical activity regardless of mA (3.3–8 mA), and divided into sexes and ages 31 to 45, 46 to 60, and 61 to 75 years old. A subset of 60 panoramic radiographs obtained by a narrow range of mA (5.7–6.4 mA) were randomly selected and then divided into sexes and ages 32 to 53 and 54 to 75 years old. Average GV was recorded. Average GV between age groups (divided by sexes) was evaluated by one-way analysis of variance (ANOVA) for groups with unrestricted mA, and unpaired t-test for restricted mA. Results: Average GV without mA restriction were not significantly different between age groups in men (P = 0.883) and women (P = 0.617). If mA is restricted, average GV was significantly different between age groups in women (P = 0.007) but were not significantly different between age groups in men (P = 0.386). Conclusion: GV obtained from panoramic radiographs may have potential in detecting osteoporosis if x-ray parameters are kept in narrow range. It would not have the same screening potential if the range of x-ray parameters are too wide.","PeriodicalId":16651,"journal":{"name":"Journal of Orofacial Sciences","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46298644","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Conference Proceedings 6th Malaysian International Dental show 第六届马来西亚国际牙科展会议记录

Journal of Orofacial Sciences Pub Date : 2023-01-01 DOI: 10.4103/jofs.jofs_207_23

引用次数: 0

Microbiological Evaluation of the Antibacterial Vicryl Suture in the Mandibular Third Molar Extraction Surgery 抗菌薇胶缝线在下颌第三磨牙拔除术中的微生物学评价

Journal of Orofacial Sciences Pub Date : 2022-07-01 DOI: 10.4103/jofs.jofs_131_22

M. Sh, Sameen Rahgozar, G. Tajmiri, J. Alizargar, S. Mirsatari

{"title":"Microbiological Evaluation of the Antibacterial Vicryl Suture in the Mandibular Third Molar Extraction Surgery","authors":"M. Sh, Sameen Rahgozar, G. Tajmiri, J. Alizargar, S. Mirsatari","doi":"10.4103/jofs.jofs_131_22","DOIUrl":"https://doi.org/10.4103/jofs.jofs_131_22","url":null,"abstract":"Introduction: Suture materials selection and application have gained more importance, especially with the increasing number of patients seeking oral surgeries. Since lying in a bacterial-filled environment, sutures make the tissue prone to infection. Suture material plays an essential role in reducing the risk of infection. This study aimed to assess the success rate of an antibacterial suture, Vicryl Plus (Ethicon Inc, Johnson and Johnson Company, Somerville, NJ), in preventing bacterial growth in the surgical site of the mandibular third molar. Materials and Methods: About 27 patients were included in this double-blinded randomized clinical trial study. Surgical extraction of the mandibular wisdom tooth was done, and the incision was managed by randomly using Vicryl Plus and Vicryl (Ethicon Inc) sutures. After 7 days, sutures were removed and assessed microbiologically. Indicator species of Streptococcus mutans and Lactobacillus were assessed, and the total number of colonies on each suture was counted. Results: There was a significant difference between the two suture materials in the colony number-length ratio of Lactobacillus (P = 0.031) and total bacterial colonies (P = 0.016), but not for S. mutans species (P = 0.201). Conclusion: Antibacterial Vicryl suture can be a useful tool to reduce bacterial accumulation on the suture material in third molar extraction surgery.","PeriodicalId":16651,"journal":{"name":"Journal of Orofacial Sciences","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2022-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46913207","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 2

A Comparative Evaluation of Apically Extruded Debris using Three Rotary and One Reciprocating Instrumentation Ni‑Ti Systems: An in Vitro Study 使用三个旋转和一个往复仪器Ni - Ti系统对根尖挤压碎片的比较评价:一项体外研究

Journal of Orofacial Sciences Pub Date : 2022-07-01 DOI: 10.4103/jofs.jofs_208_21

Maha A. Habeeb

{"title":"A Comparative Evaluation of Apically Extruded Debris using Three Rotary and One Reciprocating Instrumentation Ni‑Ti Systems: An in Vitro Study","authors":"Maha A. Habeeb","doi":"10.4103/jofs.jofs_208_21","DOIUrl":"https://doi.org/10.4103/jofs.jofs_208_21","url":null,"abstract":"Introduction: Chemomechanical preparation of root aims to eliminate the inflamed and necrotic tissue with infected dentine. This process may produce some debris extruded apically. The aim of our study was to compare and to assess the amount debris extruded apically by using four different single files systems. Materials and methods: Forty mandibular premolars which were cut to the cementoenamel junction with a diamond disk to similar lengths. Glass vials were pre-weighed and used to collect debris. The samples were divided into four groups: Group A (HyFlex EDM), Group B (AF Blue S-One), Group C (WaveOne Gold) and Group D (XPS). We used distilled water for irrigation. All canals were prepared to the size #25, then the vials were placed in hot air oven at 180°C for 5 h for evaporation of debris. Then vials containing dry debris were weighed again. The final mass of the extruded debris was calculated by subtracting the weight of initial empty vial from vial containing dry debris. ANOVA and LSD tests were applied to analyse data. Results: According to the results obtained in this study, all the tested files caused extrusion of debris apically. A highly significant difference was observed between all groups (P < 0.01). The highest value for debris extrusion was observed in rotary HyFlex EDM (0.03693 gm), whereas reciprocating C group (WaveOne Gold) showed the lowest value (0.01938 gm). Conclusion: The continuous rotary files caused less debris when compared with reciprocating one. Also all systems caused some degree of apical extrusion.","PeriodicalId":16651,"journal":{"name":"Journal of Orofacial Sciences","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2022-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48673764","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Assessment of Dental Age Estimation Using Aspartic Acid Racemization in Human Dentin in Single-Rooted Teeth 应用天冬氨酸外消旋法评估人单根牙的牙周

Journal of Orofacial Sciences Pub Date : 2022-07-01 DOI: 10.4103/jofs.jofs_90_22

Neelima Dasarathi, K. Kattappagari, V. Ponnuru, Ravi Suryaprakash, Arvind Santhosh, Baddam Venkat Reddy

{"title":"Assessment of Dental Age Estimation Using Aspartic Acid Racemization in Human Dentin in Single-Rooted Teeth","authors":"Neelima Dasarathi, K. Kattappagari, V. Ponnuru, Ravi Suryaprakash, Arvind Santhosh, Baddam Venkat Reddy","doi":"10.4103/jofs.jofs_90_22","DOIUrl":"https://doi.org/10.4103/jofs.jofs_90_22","url":null,"abstract":"Introduction: Dental age estimation has always been a very important and very susceptible subject in forensic science, as it is an essential requirement in living, dead human individual’s remains. Aspartic acid racemization is considered to be one of the advanced, reliable, accurate, and complex biochemical methods. There will be an amendment of Levo aspartic acid to dexto aspartic acid when the age advances. To estimate the dental age of single-rooted teeth using aspartic acid racemization. Material and Methods: Thirty anterior teeth were collected from maxillary and mandibular arches distributed into four groups. All teeth were analyzed for Levo (l) and Dextro (d) form of aspartic acid using a high-performance liquid chromatography technique and the ratio of amino acid racemization for each sample was determined. The obtained data were subjected to step-wise linear regression analysis for the ratio of d and l aspartic acid against actual age with estimated age. Results: Distribution of teeth about age maximum samples was collected at 51 to 60 years. l-aspartic acid ratio was more in the younger age group but when the age increases d-aspartic acid ratio was increased. Linear regression analysis showed maximum samples showed very close to the actual age (30%). Conclusion: By analyzing the levels of aspartic acid using amino acid racemization, we can estimate an individual with maximum accuracy. Accretion of d-aspartic acid in dentin is synchronous with the aging of an individual and this method can be used as one of the precise methods for dental age estimation.","PeriodicalId":16651,"journal":{"name":"Journal of Orofacial Sciences","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2022-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"45674675","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Comparison of Retention Characteristics of Clear bow Hawley’s and Vacuum Formed Retainers—A Randomized Controlled Trial Clear bow-Hawley和真空成形固位器固位特性的比较——一项随机对照试验

Journal of Orofacial Sciences Pub Date : 2022-07-01 DOI: 10.4103/jofs.jofs_259_22

Sowmithra Devi, R. Jain

{"title":"Comparison of Retention Characteristics of Clear bow Hawley’s and Vacuum Formed Retainers—A Randomized Controlled Trial","authors":"Sowmithra Devi, R. Jain","doi":"10.4103/jofs.jofs_259_22","DOIUrl":"https://doi.org/10.4103/jofs.jofs_259_22","url":null,"abstract":"Introduction: Retention is an important stage of orthodontic treatment which involves maintaining the teeth in the corrected position. The aim of this trial was to compare the retentive capacity of Clear bow Hawley (CBR) and Vacuum formed retainer (VFR) 1 year after completion of orthodontic treatment. Materials and Methods: This prospective randomized controlled trial included 46 subjects who were treated with fixed orthodontic appliances and were advised to use removable orthodontic retainers. The subjects were randomly allocated to two groups, group 1–23 subjects who received CBRs and group 2–23 subjects who received VFRs. Retainers were advised immediately after debonding and patients were recalled after 1 year. Lateral cephalograms and intraoral scans were taken and certain parameters (inter canine, intermolar width, little’s irregularity index, arch length) were evaluated. Descriptive statistics and paired t-test were done to determine and compare the retentive capacity of the retainers. Results: No statistically significant relapse was noted and no differences between retainers for inter canine, intermolar width, arch length, little’s irregularity index, and cephalometric changes were noted (P > 0.05). Conclusion: Both the CBRs and VFRs are equally effective in retaining the corrected malocclusion, CBRs can be considered as a very good alternative to VFRs.","PeriodicalId":16651,"journal":{"name":"Journal of Orofacial Sciences","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2022-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48347842","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

Antibacterial Activity of Robusta Coffee (Coffea robusta) Husk Extract Against Streptococcus mutans and Lactobacillus acidophilus: In Vitro Study 罗布斯塔咖啡(Coffea Robusta)皮提取物对变形链球菌和嗜酸乳杆菌的体外抑菌活性研究

Journal of Orofacial Sciences Pub Date : 2022-07-01 DOI: 10.4103/jofs.jofs_157_22

Arlin Kusumawardani, Andi Machbub, RendraKurniawan Prasetya, Nadie Fatimatuzzahro, T. Ermawati

{"title":"Antibacterial Activity of Robusta Coffee (Coffea robusta) Husk Extract Against Streptococcus mutans and Lactobacillus acidophilus: In Vitro Study","authors":"Arlin Kusumawardani, Andi Machbub, RendraKurniawan Prasetya, Nadie Fatimatuzzahro, T. Ermawati","doi":"10.4103/jofs.jofs_157_22","DOIUrl":"https://doi.org/10.4103/jofs.jofs_157_22","url":null,"abstract":"Introduction: Caries is a tooth and oral illness caused by Streptococcus mutans and Lactobacillus acidophilus bacteria. The growth of caries-causing bacteria can be controlled by using 0.2% chlorhexidine mouthwash to control plaque, however long-term usage of 0.2% chlorhexidine causes negative effects. Natural components such as robusta coffee (Coffea robusta) husk, which possesses active compounds of polyphenols, flavonoids, alkaloids, tannins, and saponins as alternative antibacterials, can be used to reduce adverse effects. The aim of this research is to assess the antibacterial activity of robusta coffee husk extract against S. mutans and L. acidophilus. Materials and Methods: The robusta coffee husk was extracted using the maceration process with 96% ethanol as the solvent. Antibacterial test is conducted against S. mutans and L. acidophilus using disc diffusion method (Kirby-Baurer) with six treatment groups of extract concentration 250, 500, 750, 1000 mg/mL, positive control (0.2% chlorhexidine), and negative control (aquades steril). The zone of inhibition was measured in millimetres using a digital calliper (mm). The SPSS application was used to examine the calculation findings, which included the Shapiro-Wilk, Levene, One Way ANOVA, and Post Hoc LSD tests. Results: Robusta coffee husk extract at 250, 500, 750, and 1000 mg/mL doses shown bactericidal activity in S. mutans (radical zone) and bacteriostatic activity in L. acidophilus (irradical zone). Conclusion: Robusta coffee husk extract has an antibacterial activity against S. mutans and L. acidophilus. The highest inhibition zone was demonstrated by the 1000 mg/mL concentration of extract.","PeriodicalId":16651,"journal":{"name":"Journal of Orofacial Sciences","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2022-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"45339673","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0