Julien Luraschi, Mayuresh S Korgaonkar, Terry Whittle, Martin Schimmel, Frauke Müller, Iven Klineberg
{"title":"Neuroplasticity in the adaptation to prosthodontic treatment.","authors":"Julien Luraschi, Mayuresh S Korgaonkar, Terry Whittle, Martin Schimmel, Frauke Müller, Iven Klineberg","doi":"10.11607/jop.1097","DOIUrl":"https://doi.org/10.11607/jop.1097","url":null,"abstract":"<p><strong>Aims: </strong>To investigate cerebral cortical changes by using functional magnetic resonance imaging (fMRI) after denture renewal and to test how these relate to prosthodontic treatment adaptability as measured by chewing efficiency and maximum bite force.</p><p><strong>Methods: </strong>Ten complete denture wearers (five women and five men, mean age ± standard deviation: 70.3 ± 9.1 years) participated in the study. Each had their complete dentures renewed and underwent an fMRI examination with three functional tasks (lip pursing; jaw tapping; jaw clenching) as well as a color-mixing test for chewing efficiency and unilateral maximum bite force measurements. Recordings were performed with the old dentures (T0) and with the new dentures on insertion (T1) and at 1 week (T2) and 3 months postinsertion (T3). At T1, denture stability and retention (S/T) were assessed by two independent operators. Wilcoxon signed rank tests and Spearman's rho correlation were carried out for data analysis.</p><p><strong>Results: </strong>The right and the left precentral gyrus (PRCG) and postcentral gyrus (POCG) were identified with significant activation across all three functional tasks. A statistically significant increase in the level of activity between T0 and T2 (POCG: P = .022; PRCG: P = .017) was found during jaw clenching tasks. Both regions of interest (PRCG, POCG) appeared to correlate with S/T of the new dentures while the subject performed a lip-pursing task (PRCG: r = 0.689, P = .027; POCG: r = 0.665, P = .036). The chewing efficiency and maximum bite force increased significantly during the adaptation to replacement dentures (chewing efficiency: T1-T2 P = .032, T2-T3 P = .012; maximum bite force right side: T2-T3 P = .047).</p><p><strong>Conclusion: </strong>Changes in brain activity occurred in the adaptation to replacement dentures and appeared to regain preinsertion activity levels during motor tasks involving the dental occlusion after 3 months postinsertion.</p>","PeriodicalId":16649,"journal":{"name":"Journal of orofacial pain","volume":"27 3","pages":"206-16"},"PeriodicalIF":0.0,"publicationDate":"2013-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.11607/jop.1097","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"31245424","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Afshin Haraji, Vahid Rakhshan, Naiemeh Khamverdi, Hadiseh Khanzadeh Alishahi
{"title":"Effects of intra-alveolar placement of 0.2% chlorhexidine bioadhesive gel on dry socket incidence and postsurgical pain: a double-blind split-mouth randomized controlled clinical trial.","authors":"Afshin Haraji, Vahid Rakhshan, Naiemeh Khamverdi, Hadiseh Khanzadeh Alishahi","doi":"10.11607/jop.1142","DOIUrl":"https://doi.org/10.11607/jop.1142","url":null,"abstract":"<p><strong>Aims: </strong>To assess the effects of intra-alveolar application of chlorhexidine gel on the incidence of alveolar osteitis (dry socket) and the severity of postsurgical pain.</p><p><strong>Methods: </strong>A total of 160 impacted mandibular third molars were extracted in 80 patients enrolled in this trial. In each subject, a socket was randomly selected and packed to the crest of the alveolar ridge with a gelatin sponge dressing saturated in 0.2% chlorhexidine gel. The contralateral socket was packed with a dry dressing as the placebo. None of the included patients took antibiotics or analgesics. The occurrence of dry socket and patients' pain levels were assessed at the first and third postoperative days. The data were analyzed using Spearman correlation coefficient, McNemar, Wilcoxon, and chi-square tests.</p><p><strong>Results: </strong>Chlorhexidine gel significantly reduced dry socket incidence from 32.6% to 11.3% (P ≤ .001 [McNemar and chi-square], absolute risk reduction = 21.2%, relative risk reduction = 65.4%, odds ratio = 0.263, relative risk = 0.345). It also significantly relieved postoperative pain on both sides in all the patients (P ≤ .001 [Wilcoxon]) and also in the 54 subjects who did not develop dry socket (P ≤ .001 [Wilcoxon]).</p><p><strong>Conclusions: </strong>Besides decreasing the incidence of dry socket, chlorhexidine gel can reduce postsurgical pain in patients with and without dry socket.</p>","PeriodicalId":16649,"journal":{"name":"Journal of orofacial pain","volume":"27 3","pages":"256-62"},"PeriodicalIF":0.0,"publicationDate":"2013-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.11607/jop.1142","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"31245429","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Quality and content of internet-based information on temporomandibular disorders.","authors":"Min Woo Park, Jeong Hwan Jo, Ji Woon Park","doi":"","DOIUrl":"","url":null,"abstract":"<p><strong>Aims: </strong>To use a range of evaluation instruments to assess the content and quality of websites about temporomandibular disorders (TMD) and thereby provide guidance regarding the actual accuracy and comprehensiveness of the information of the sites.</p><p><strong>Methods: </strong>Sixty-seven websites resulting from an Internet search with the word \"TMD\" were evaluated using Journal of the American Medical Association (JAMA), DISCERN, and Health on the Net (HON) criteria, along with an evaluation method to assess the scientific quality of the website contents. Results were compared according to reviewer, website type, and presence of HON seal. One-way analysis of variance (ANOVA), Student t test, chi-square test, and Pearson correlation analysis were used as appropriate.</p><p><strong>Results: </strong>The mean content, HON, and DISCERN scores were 38.9%, below 50%, and 53.9% of the maximum possible score, respectively. Fewer than 50% of the sites displayed the author or reference of the information according to the JAMA benchmarks criteria. Every evaluation criteria showed good agreement among reviewers. Commercial websites were the most common, while sites of nonprofit organizations showed the highest content scores. The overall quality was poor to moderate for all website types.</p><p><strong>Conclusion: </strong>Sites concerning TMD were poorly organized and maintained. Also, most sites contained insufficient or scientifically incorrect information that could have a negative effect on the treatment outcome and prognosis of TMD. Clinicians should guide patients to reputable sources of information that will enhance patient comprehension and better treatment outcomes.</p>","PeriodicalId":16649,"journal":{"name":"Journal of orofacial pain","volume":"26 4","pages":"296-306"},"PeriodicalIF":0.0,"publicationDate":"2012-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"31013049","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Lack of temporal summation but distinct aftersensations to thermal stimulation in patients with combined tension-type headache and myofascial temporomandibular disorder.","authors":"Hitoshi Sato, Hironori Saisu, Wataru Muraoka, Taneaki Nakagawa, Peter Svensson, Koichi Wajima","doi":"","DOIUrl":"","url":null,"abstract":"<p><strong>Aims: </strong>To compare patients with combined tension-type headache and myofascial temporomandibular disorder (TMD) with control subjects on two measures of central processing-ie, temporal summation and aftersensations to heat stimulation in the trigeminal nerve and spinal nerve territories.</p><p><strong>Methods: </strong>A novel heat stimulation protocol was used in which 13 females with tension-type headache/TMD and 20 female controls were exposed to 11 painful heat stimuli at a rate of 0.33 Hz. Two temperature ranges (low, 44°C to 46°C; high, 45°C to 47°C) were tested on the cheek and arm in separate trials. Perceived pain was rated on a 100-mm visual analog scale after the second, sixth, and eleventh stimulus presentation and every 15 seconds after the final stimulus presentation (aftersensations) for up to 3 minutes. The duration of aftersensations was compared using the student unpaired t test with Welch correction.</p><p><strong>Results: </strong>Temporal summation was not observed in any of the groups, but aftersensations were consistently reported. The aftersensations lasted longer in tension-type headache/TMD patients (right cheek, 100.4 ± 62.0 seconds; right arm, 115.4 ± 64.0 seconds) than in controls (right cheek, 19.5 ± 2.5 seconds; right arm, 20.3 ± 2.7 seconds) (P < .05). A cutoff value (right cheek, 44.6 seconds; right arm, 41.5 seconds) provided a sensitivity and specificity of 0.77 and 0.95, respectively, with the high stimulus protocol.</p><p><strong>Conclusion: </strong>The results from this pilot study suggest that aftersensations to painful heat stimulation can appear without temporal summation. Furthermore, the developed test protocol has a good predictive value and may have the potential to discriminate between tension-type headache/TMD patients and control subjects.</p>","PeriodicalId":16649,"journal":{"name":"Journal of orofacial pain","volume":"26 4","pages":"288-95"},"PeriodicalIF":0.0,"publicationDate":"2012-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"31013646","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Ida Marini, Maria Lavinia Bartolucci, Francesco Bortolotti, Maria Rosaria Gatto, Giulio Alessandri Bonetti
{"title":"Palmitoylethanolamide versus a nonsteroidal anti-inflammatory drug in the treatment of temporomandibular joint inflammatory pain.","authors":"Ida Marini, Maria Lavinia Bartolucci, Francesco Bortolotti, Maria Rosaria Gatto, Giulio Alessandri Bonetti","doi":"","DOIUrl":"","url":null,"abstract":"<p><strong>Aims: </strong>To carry out a randomized clinical trial to compare the effect of palmitoylethanolamide (PEA) versus ibuprofen, a nonsteroidal anti-inflammatory drug (NSAID), for pain relief in temporomandibular joint (TMJ) osteoarthritis or arthralgia. PEA acts as an endogenous agent with an autacoid local inflammation antagonism and modulates mast cell behavior controlling both acute and chronic inflammation.</p><p><strong>Methods: </strong>A triple-blind randomized clinical trial was conducted on 24 patients (16 women and 8 men) aged 24 to 54 years and suffering from TMJ osteoarthritis or arthralgia. The patients were enrolled from a group of 120 consecutive patients referred to the University of Bologna's Department of Orthodontics. Patients were randomly divided into two groups: group A (12 subjects) received PEA 300 mg in the morning and 600 mg in the evening for 7 days and then 300 mg twice a day for 7 more days. Group B (12 subjects) received ibuprofen 600 mg three times a day for 2 weeks. Every patient recorded the intensity of spontaneous pain on a visual analog scale twice a day. Maximum mouth opening was recorded by a blind operator during the first visit and again after the 14th day of drug treatment. A t test was used for data comparisons.</p><p><strong>Results: </strong>Pain decrease after 2 weeks of treatment was significantly higher in group A than in group B (P = .0001); maximum mouth opening improved more in group A than in group B (P = .022).</p><p><strong>Conclusion: </strong>These data suggest that PEA is effective in treating TMJ inflammatory pain.</p>","PeriodicalId":16649,"journal":{"name":"Journal of orofacial pain","volume":"26 2","pages":"99-104"},"PeriodicalIF":0.0,"publicationDate":"2012-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"30593784","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Karina Haugaard Bendixen, Astrid Juhl Terkelsen, Lene Baad-Hansen, Brian E Cairns, Peter Svensson
{"title":"Experimental stressors alter hypertonic saline-evoked masseter muscle pain and autonomic response.","authors":"Karina Haugaard Bendixen, Astrid Juhl Terkelsen, Lene Baad-Hansen, Brian E Cairns, Peter Svensson","doi":"","DOIUrl":"","url":null,"abstract":"<p><strong>Aims: </strong>To test in a randomized controlled trial, if hypertonic saline (HS)-evoked pain and autonomic function are modulated by either a cold pressor test (CPT) or mental arithmetic stress induced by a paced auditory serial addition task (PASAT).</p><p><strong>Methods: </strong>Fourteen healthy women participated in three sessions. Pain was induced by two 5% HS infusions (5 minutes each, 30 minutes apart) infused into the masseter muscle. During the second HS infusion, pain was modulated by PASAT, CPT, or control (HS alone). HS-evoked pain intensity was scored on a 0 to 10 numeric rating scale (NRS). Heart rate variability (HRV) and hemodynamic measures were recorded noninvasively (Task Force Monitor). Data were analyzed using repeated measurements ANOVAs and Spearman correlation analysis.</p><p><strong>Results: </strong>HS-evoked pain was significantly and similarly reduced by both PASAT (30.8 ± 27.6%; P < .001) and CPT (35.8 ± 26.6%; P < .001) compared with the control session (9.0 ± 30.5%; P > .05). PASAT and CPT increased the heart rate compared with control (P <.001). CPT reduced measures of vagal activity: Root mean square successive difference, high-frequency (HF) power, and coefficient of HF component variance compared with an internal control, ie, the first HS infusion (P < .05), while PASAT did not alter any of these HRV measures (P > .05).</p><p><strong>Conclusion: </strong>CPT and PASAT reduced HS-evoked masseter muscle pain and altered the autonomic response. The increase in heart rate following CPT and PASAT may be caused by different mechanisms. CPT reduced measures of efferent cardiac vagal (parasympathetic) activity, while the PASAT-induced increase in heart rate, but unchanged HRV, may suggest neurohumoral activation.</p>","PeriodicalId":16649,"journal":{"name":"Journal of orofacial pain","volume":"26 3","pages":"191-205"},"PeriodicalIF":0.0,"publicationDate":"2012-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"30794376","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Temporomandibular joint structural derangement and general joint hypermobility.","authors":"Huey-Yuan Wang, Tiffany Ting-Fang Shih, Juo-Song Wang, Yuh-Yuan Shiau, Yunn-Jy Chen","doi":"","DOIUrl":"","url":null,"abstract":"<p><strong>Aim: </strong>To explore the relationship between general joint hypermobility (GJH) and displacement of the temporomandibular joint (TMJ) disc as evident from magnetic resonance imaging (MRI).</p><p><strong>Methods: </strong>Fifth finger extension, thumb apposition, elbow extension, knee extension, trunk flexion, and ankle dorsiflexion were measured in 66 young female patients with MRI-evident TMJ internal derangement (ID) and in 30 age-matched female controls. The Beighton score of each subject was measured quantitatively. The possible association between TMJ ID and mobility of a single joint or index of GJH, ie, the Beighton score, were assessed with one-way ANOVA with post-hoc Bonferroni and chi-square test, respectively. Correlations of the mobility of every measured joint were also explored.</p><p><strong>Results: </strong>Very few of the TMJ ID patients and control subjects were diagnosed with GJH according to the Beighton score. The Beighton score did not differentiate between subjects with and without TMJ ID. Subjects with TMJ ID, especially patients with MRI-evident disc displacement without reduction, seemed to have a stiffer trunk than controls, but this may not be of clinical relevance. The mobilities of paired joints were significantly correlated; however, the mobilities of different anatomical joints seemed to be independent.</p><p><strong>Conclusion: </strong>Based on the Beighton score, GJH does not seem to be a reliable indicator of the presence of TMJ ID.</p>","PeriodicalId":16649,"journal":{"name":"Journal of orofacial pain","volume":"26 1","pages":"33-8"},"PeriodicalIF":0.0,"publicationDate":"2012-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"30425238","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Pain advocacy: the evolution continues, with further calls for action.","authors":"Barry Sessle","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":16649,"journal":{"name":"Journal of orofacial pain","volume":"26 1","pages":"5"},"PeriodicalIF":0.0,"publicationDate":"2012-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"30426374","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Nan Nan Zhao, Terry Whittle, Greg M Murray, Christopher C Peck
{"title":"The effects of capsaicin-induced intraoral mucosal pain on jaw movements in humans.","authors":"Nan Nan Zhao, Terry Whittle, Greg M Murray, Christopher C Peck","doi":"","DOIUrl":"","url":null,"abstract":"<p><strong>Aims: </strong>To determine whether mucosal pain, evoked through a novel topical capsaicin model, has an effect on jaw movement and whether psychologic factors have an association with any pain-induced movement effects.</p><p><strong>Methods: </strong>Mandibular movement was recorded from 26 asymptomatic subjects during free opening and closing, resistant opening jaw movements, and free and standardized chewing, at baseline and in test sessions while the subjects were wearing a custom maxillary mouthguard coated with either capsaicin cream (pain group, 13 subjects) or placebo cream (control group, an additional 13 subjects). All subjects completed the Depression Anxiety Stress Scales (DASS) and the Pain Catastrophizing Scale (PCS). Statistical analyses were made with independent t tests and bivariate correlation analyses.</p><p><strong>Results: </strong>Capsaicin induced moderate pain in the pain group, but there were no significant differences between the two groups in the change of kinematic variables from baseline except for a significantly greater increase from baseline in the number of chewing cycles per second (chewing rate) for free (t = 2.74, P = .011) and standardized chewing (t = 2.10, P = .047) in the pain group compared with the control group. In the pain group, the DASS anxiety score was negatively correlated (r = -.70, P = .007), with the change of mean opening velocity from the baseline to the test session in the free opening task, and the DASS depression score was negatively correlated to the increase of chewing rate in the free chewing task from the baseline to the test session (r = -.56, P = .046).</p><p><strong>Conclusion: </strong>Capsaicin-induced mucosal pain resulted in a significant increase in chewing rate but had no effect on amplitude or velocity in opening/closing jaw movements and chewing. Anxiety and depression scores correlated negatively with velocity in free opening jaw movement and chewing rate, respectively.</p>","PeriodicalId":16649,"journal":{"name":"Journal of orofacial pain","volume":"26 4","pages":"277-87"},"PeriodicalIF":0.0,"publicationDate":"2012-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"31013645","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
James Wayne King, Eric Bair, Derek Duggan, William Maixner, Asma A Khan
{"title":"The relationship between resting arterial blood pressure and acute postoperative pain in endodontic patients.","authors":"James Wayne King, Eric Bair, Derek Duggan, William Maixner, Asma A Khan","doi":"","DOIUrl":"","url":null,"abstract":"<p><strong>Aims: </strong>To evaluate the relationship between preoperative resting arterial blood pressure and postoperative pain in patients undergoing nonsurgical root canal therapy.</p><p><strong>Methods: </strong>Written informed consent was obtained from normotensive patients seeking treatment for teeth with a preoperative diagnosis of pulpal necrosis and periradicular periodontitis. Preoperative resting blood pressure was recorded, and nonsurgical root canal therapy was initiated using a standardized protocol. Patients recorded their pre- and postoperative pain intensity on a 100-mm visual analog scale (VAS) for 7 days after the procedure. A linear regression model to predict postoperative VAS intensity used preoperative pain and blood pressure values as covariates. Pearson correlations were calculated to assess the relationship between the measures of preoperative blood pressure and both pre- and postoperative pain.</p><p><strong>Results: </strong>After controlling for preoperative pain, significant correlations were observed between preoperative systolic blood pressure and postoperative pain (P < .05), as well as between preoperative pulse pressure and postoperative pain (P < .005) on day 1.</p><p><strong>Conclusion: </strong>This study has provided further evidence of a functional interaction between the cardiovascular and trigeminal pain regulatory systems. Understanding this complex relationship may lead to enhanced pain management strategies.</p>","PeriodicalId":16649,"journal":{"name":"Journal of orofacial pain","volume":"26 4","pages":"321-7"},"PeriodicalIF":0.0,"publicationDate":"2012-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4208728/pdf/nihms630672.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"31013052","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}