Journal of paediatrics and child health最新文献

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Two Different Paths of Treatment for Relapsed-Refractory Infantile Fibrosarcoma: Classical or Trendy?
IF 1.6 4区 医学
Journal of paediatrics and child health Pub Date : 2025-03-20 DOI: 10.1111/jpc.70039
Funda Tekkesin, Begum Sirin Koc, Selime Aydogdu, Dilek Ece, Sevinc Tasar, İlkay Tosun, Suar Caki Kilic
{"title":"Two Different Paths of Treatment for Relapsed-Refractory Infantile Fibrosarcoma: Classical or Trendy?","authors":"Funda Tekkesin, Begum Sirin Koc, Selime Aydogdu, Dilek Ece, Sevinc Tasar, İlkay Tosun, Suar Caki Kilic","doi":"10.1111/jpc.70039","DOIUrl":"https://doi.org/10.1111/jpc.70039","url":null,"abstract":"","PeriodicalId":16648,"journal":{"name":"Journal of paediatrics and child health","volume":" ","pages":""},"PeriodicalIF":1.6,"publicationDate":"2025-03-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143663393","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Rare Neonatal Fungal Infection: Trichophyton Rubrum as a Cause of Dermatophytosis.
IF 1.6 4区 医学
Journal of paediatrics and child health Pub Date : 2025-03-19 DOI: 10.1111/jpc.70038
Sofia Maria Silva Faria, Inês Fátima Neto Gandra, Catarina Homem Gouveia Neto Viveiros, Joel Lopes Reis, Ana Cristina Santos Oliveira, Maria Antónia Cordeiro Read, Ana Isabel Aldeia Azevedo
{"title":"Rare Neonatal Fungal Infection: Trichophyton Rubrum as a Cause of Dermatophytosis.","authors":"Sofia Maria Silva Faria, Inês Fátima Neto Gandra, Catarina Homem Gouveia Neto Viveiros, Joel Lopes Reis, Ana Cristina Santos Oliveira, Maria Antónia Cordeiro Read, Ana Isabel Aldeia Azevedo","doi":"10.1111/jpc.70038","DOIUrl":"https://doi.org/10.1111/jpc.70038","url":null,"abstract":"","PeriodicalId":16648,"journal":{"name":"Journal of paediatrics and child health","volume":" ","pages":""},"PeriodicalIF":1.6,"publicationDate":"2025-03-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143657402","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Determinants of Gross Motor Function in Children With Ambulatory Spastic Cerebral Palsy: A Cross-Sectional Study in Turkey.
IF 1.6 4区 医学
Journal of paediatrics and child health Pub Date : 2025-03-18 DOI: 10.1111/jpc.70034
Atahan Turhan, Merve Kurt-Aydin, Tülay Tarsuslu
{"title":"Determinants of Gross Motor Function in Children With Ambulatory Spastic Cerebral Palsy: A Cross-Sectional Study in Turkey.","authors":"Atahan Turhan, Merve Kurt-Aydin, Tülay Tarsuslu","doi":"10.1111/jpc.70034","DOIUrl":"https://doi.org/10.1111/jpc.70034","url":null,"abstract":"<p><strong>Aim: </strong>This study aims to explore the determinants of gross motor function in ambulatory children with spastic cerebral palsy (CP).</p><p><strong>Methods: </strong>Sixty-eight children diagnosed with spastic CP type were included in the study. Sociodemographic and clinical information of children with CP and their families was recorded. Children's gross motor function level was classified using the Gross Motor Function Classification System; gross motor function was assessed using the Gross Motor Function Measure-66 (GMFM-66); and parental quality of life was assessed using the Paediatric Quality of Life Scale Family Effects Module (PedsQL-FIM).</p><p><strong>Results: </strong>No significant differences were observed in gross motor function or parental quality of life between hemiparetic and diparetic CP groups. However, children residing in urban areas showed significantly higher gross motor function and parental quality of life compared to those in rural areas (p < 0.05). Moderate correlations were found between gross motor function and physical functioning as well as place of residence (p < 0.05). Multiple regression indicated that physical functioning and urban residence were significant predictors of gross motor function, accounting for 37.9% of the variance in the GMFM-66 score.</p><p><strong>Conclusion: </strong>This study shows that the quality of life of parents of children and residence in the urban area are independent predictors of gross motor function in children with CP. These findings highlight the importance of considering family well-being and environmental factors when developing interventions to improve gross motor function outcomes in children with CP.</p><p><strong>Trial registration: </strong>NCT06439446.</p>","PeriodicalId":16648,"journal":{"name":"Journal of paediatrics and child health","volume":" ","pages":""},"PeriodicalIF":1.6,"publicationDate":"2025-03-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143649414","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Challenge in a Malrotation Case: Presentation Mimicking Severe Combined Immunodeficiency.
IF 1.6 4区 医学
Journal of paediatrics and child health Pub Date : 2025-03-13 DOI: 10.1111/jpc.70030
Jana Fathelbab, Deniz Cagdas, Dicle Canoruc Emet, Berna Oguz, Fatih Andiran
{"title":"Challenge in a Malrotation Case: Presentation Mimicking Severe Combined Immunodeficiency.","authors":"Jana Fathelbab, Deniz Cagdas, Dicle Canoruc Emet, Berna Oguz, Fatih Andiran","doi":"10.1111/jpc.70030","DOIUrl":"https://doi.org/10.1111/jpc.70030","url":null,"abstract":"<p><strong>Objectives: </strong>Malrotation is a congenital anomaly characterized by improper positioning of the intestines that can cause a range of symptoms from asymptomatic to life-threatening, including midgut volvulus. Diagnosis of malrotation can be particularly challenging in cases where symptoms resemble those of other illnesses, such as severe combined immunodeficiency (SCID).</p><p><strong>Case report: </strong>In this case study, we describe a 2-month-old girl with midgut volvulus secondary to malrotation. She was initially diagnosed with SCID and referred to our center for hematopoietic stem cell transplantation (HSCT). However, her gastrointestinal (GI) problems persisted even after receiving treatment for a suspected immunodeficiency. Imaging finally revealed the underlying malrotation. Unfortunately, by that time, the patient had developed major consequences, such as intestinal perforation, sepsis, and eventually death as a result of the delayed diagnosis.</p><p><strong>Conclusions: </strong>This case highlights how crucial it is to take GI anomalies into account when making a differential diagnosis for newborns who present with sepsis and immune suppression. Early imaging and a multidisciplinary approach are essential for timely diagnosis and treatment to prevent the progression to a fatal outcome.</p>","PeriodicalId":16648,"journal":{"name":"Journal of paediatrics and child health","volume":" ","pages":""},"PeriodicalIF":1.6,"publicationDate":"2025-03-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143623497","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Prolonged Fever in Children: An Inpatient Diagnostic Framework for Infections in Australia
IF 1.6 4区 医学
Journal of paediatrics and child health Pub Date : 2025-03-13 DOI: 10.1111/jpc.70027
Heshani Rupasinghe, Clare Nourse, Jennifer Robson, Angela Berkhout
{"title":"Prolonged Fever in Children: An Inpatient Diagnostic Framework for Infections in Australia","authors":"Heshani Rupasinghe,&nbsp;Clare Nourse,&nbsp;Jennifer Robson,&nbsp;Angela Berkhout","doi":"10.1111/jpc.70027","DOIUrl":"10.1111/jpc.70027","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <p>There are many causes of fever in children, ranging from common and self-limiting to serious and life threatening. Careful assessment of children with prolonged fever without an obvious or identified source requires detailed history and examination with consideration of infections unique to the specific geographical region and individual exposure risks. Previous recommendations for diagnostic work-up have provided valuable insights, but none have been tailored to the Australian inpatient setting. Recognising this gap, a diagnostic approach for infections specifically designed for the Australian child admitted to hospital with prolonged fever (<span></span><math>\u0000 <semantics>\u0000 <mrow>\u0000 <mo>≥</mo>\u0000 </mrow>\u0000 </semantics></math> 38.0°C) exceeding 7 days is provided.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Level of Evidence</h3>\u0000 \u0000 <p>National Health and Medical Research Council Level V.</p>\u0000 </section>\u0000 </div>","PeriodicalId":16648,"journal":{"name":"Journal of paediatrics and child health","volume":"61 4","pages":"532-539"},"PeriodicalIF":1.6,"publicationDate":"2025-03-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1111/jpc.70027","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143623499","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Stay Put or Move Out? A Review of Acute Respiratory Illness Transfers Out of a Peripheral Centre and Their Characteristics: A Retrospective Cohort Study.
IF 1.6 4区 医学
Journal of paediatrics and child health Pub Date : 2025-03-13 DOI: 10.1111/jpc.70033
James Pho, Alison Tran, Mani Suleiman, David Tran, Wei Qi Fan, Rebekah Barker, Rami Subhi
{"title":"Stay Put or Move Out? A Review of Acute Respiratory Illness Transfers Out of a Peripheral Centre and Their Characteristics: A Retrospective Cohort Study.","authors":"James Pho, Alison Tran, Mani Suleiman, David Tran, Wei Qi Fan, Rebekah Barker, Rami Subhi","doi":"10.1111/jpc.70033","DOIUrl":"https://doi.org/10.1111/jpc.70033","url":null,"abstract":"<p><strong>Aim: </strong>To describe the characteristics of children transferred out of a peripheral centre for the management of acute respiratory illness and explore opportunities for decentralising paediatric high dependency care.</p><p><strong>Methods: </strong>A single-centre, retrospective cohort study, including children transferred out of a peripheral centre with diagnoses of asthma, bronchiolitis, pneumonia and pleural effusion. Patient characteristics and management were recorded from the medical records. Transfers were classified as 'within scope' and 'outside scope' of a peripheral paediatric centre. A multivariate regression was used to identify predictors of within scope transfers.</p><p><strong>Results: </strong>Between September 2015 and September 2023, there were 852 transfers, of which 165 (19.4%) met the study inclusion criteria. Ninety-three (56.4%) transfers were within scope. Pre-transfer diagnoses of preschool asthma, bronchiolitis, use of high flow nasal prong therapy (HFNP) and transfer directly from the emergency department (rather than ward) were more common for within scope transfers. HFNP was used in 103 (62.4%) of patients, including 74 (79.6%) of within scope transfers. Within scope transfers were predicted by preschool asthma (aOR 17.1, 95% CI 2.1-142.2, p = 0.01) and HFNP therapy pre-transfer (aOR 5.4, 95% CI 2.2-13.2, p < 0.0001).</p><p><strong>Conclusion: </strong>This study shows a cohort of patients that could benefit from a model of care involving decentralising paediatric high dependency care, particularly children with preschool asthma, and those transferred for closer monitoring on HFNP therapy. More work needs to be done to define the scope of practice, guidelines and training, staffing and resourcing and systems for safety netting.</p>","PeriodicalId":16648,"journal":{"name":"Journal of paediatrics and child health","volume":" ","pages":""},"PeriodicalIF":1.6,"publicationDate":"2025-03-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143623501","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Developmental and Psychological Concerns in Children With Complex Congenital Heart Disease: The Need for a Screening Program.
IF 1.6 4区 医学
Journal of paediatrics and child health Pub Date : 2025-03-06 DOI: 10.1111/jpc.70032
Ashani Mahawattege, Karina Laohachai
{"title":"Developmental and Psychological Concerns in Children With Complex Congenital Heart Disease: The Need for a Screening Program.","authors":"Ashani Mahawattege, Karina Laohachai","doi":"10.1111/jpc.70032","DOIUrl":"https://doi.org/10.1111/jpc.70032","url":null,"abstract":"<p><strong>Aim: </strong>Complex congenital heart disease (CHD) is associated with adverse neurodevelopmental and psychological outcomes. Limited Australian data exist regarding these outcomes or follow-up. This cross-sectional study aims to determine the prevalence of developmental and psychological concerns in South Australian children with complex CHD and concurrent developmental or psychological healthcare utilisation.</p><p><strong>Methods: </strong>Families of children with complex CHD aged between 3 years and 7 years 11 months undertook a series of validated screening questionnaires for development (Parents' Evaluation of Developmental Status [PEDS], Parents' Evaluation of Developmental Status-Developmental Milestones [PEDS:DM]) and mental health (Strengths and Difficulties Questionnaire [SDQ]). Demographic data, cardiac history, comorbidities, and current healthcare engagement was determined through standardised patient information questionnaires and medical records. Rates of developmental and psychological concern were determined and compared to Australian general population data.</p><p><strong>Results: </strong>Fifty-five participants enrolled in the study. The most common cardiac diagnoses were Transposition of the Great Arteries (n = 13) and Tetralogy of Fallot (n = 11). Predictive developmental domain/s of concern were highly prevalent utilising both PEDS (57%) and PEDS:DM (70%) screening tools, exceeding Australian population rates (22%). Psychological concern (28%) also exceeded Australian population data (10%). Nearly half of participants identified to have developmental or psychological concern/s had no current general paediatric, allied health or mental health professional engagement.</p><p><strong>Conclusions: </strong>Developmental and psychological concerns detected on screening in children with complex CHD significantly exceed Australian general population prevalence rates. Without an established screening program, a large proportion of participants did not have active follow-up, indicating the importance of routine screening.</p>","PeriodicalId":16648,"journal":{"name":"Journal of paediatrics and child health","volume":" ","pages":""},"PeriodicalIF":1.6,"publicationDate":"2025-03-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143573295","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Extreme Sinus Bradycardia in a 36-Week Neonate Caused by De Novo Short QT Syndrome: A Case Report. 新发短 QT 综合征导致 36 周新生儿出现极度窦性心动过缓:病例报告。
IF 1.6 4区 医学
Journal of paediatrics and child health Pub Date : 2025-03-06 DOI: 10.1111/jpc.70026
Nicole Minto, James Tong
{"title":"Extreme Sinus Bradycardia in a 36-Week Neonate Caused by De Novo Short QT Syndrome: A Case Report.","authors":"Nicole Minto, James Tong","doi":"10.1111/jpc.70026","DOIUrl":"https://doi.org/10.1111/jpc.70026","url":null,"abstract":"","PeriodicalId":16648,"journal":{"name":"Journal of paediatrics and child health","volume":" ","pages":""},"PeriodicalIF":1.6,"publicationDate":"2025-03-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143573297","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Association Between Hammersmith Infant Neurological Examination and Bayley Scales of Infant Development in High-Risk Infants: A Retrospective Cohort Study. 高风险婴儿的哈默史密斯婴儿神经系统检查和贝利婴儿发育量表之间的关系:回顾性队列研究
IF 1.6 4区 医学
Journal of paediatrics and child health Pub Date : 2025-03-06 DOI: 10.1111/jpc.70031
Meagan Roff, Brendan Tian, Emily Johnston, Vathana Sackett, Annie Bourke, Pramod Pharande, Lindsay Zhou, Abdul Razak, Atul Malhotra
{"title":"Association Between Hammersmith Infant Neurological Examination and Bayley Scales of Infant Development in High-Risk Infants: A Retrospective Cohort Study.","authors":"Meagan Roff, Brendan Tian, Emily Johnston, Vathana Sackett, Annie Bourke, Pramod Pharande, Lindsay Zhou, Abdul Razak, Atul Malhotra","doi":"10.1111/jpc.70031","DOIUrl":"https://doi.org/10.1111/jpc.70031","url":null,"abstract":"","PeriodicalId":16648,"journal":{"name":"Journal of paediatrics and child health","volume":" ","pages":""},"PeriodicalIF":1.6,"publicationDate":"2025-03-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143573294","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Do the American Academy of Paediatrics Guidelines for Managing Febrile Infants Aged 22 to 28 Days Work for a Suburban Australian Emergency Department? A Retrospective Audit.
IF 1.6 4区 医学
Journal of paediatrics and child health Pub Date : 2025-03-05 DOI: 10.1111/jpc.70025
Claudia O'Rourke, David Krieser, Areeba Athar, Vidanka Vasilevski, Linda Sweet, Doris Tham
{"title":"Do the American Academy of Paediatrics Guidelines for Managing Febrile Infants Aged 22 to 28 Days Work for a Suburban Australian Emergency Department? A Retrospective Audit.","authors":"Claudia O'Rourke, David Krieser, Areeba Athar, Vidanka Vasilevski, Linda Sweet, Doris Tham","doi":"10.1111/jpc.70025","DOIUrl":"https://doi.org/10.1111/jpc.70025","url":null,"abstract":"<p><strong>Aim: </strong>The American Academy of Paediatrics (AAP) 2021 guideline on the management of febrile infants provides a separate algorithm for the 22- to 28-day-old infant. Provided a specific combination of inflammatory markers is in the low-risk range, lumbar puncture (LP) and empiric antibiotics are optional. The Australian guidelines recommend LP and empiric antibiotics in all febrile neonates (< 29 days). We describe the management of this age group over 8 years and review how using the AAP guideline would alter management.</p><p><strong>Methods: </strong>A single-centre retrospective chart review was conducted at Sunshine Hospital, Melbourne. The medical records of 50 consecutive well-appearing febrile infants aged 22-28 days were reviewed. Data on investigations, antibiotics, and duration of hospital stay were compared to the AAP recommendations.</p><p><strong>Results: </strong>Of the 45 patients who met the inclusion criteria, 31% had no LP and 18% were observed without antibiotics. In the setting of normal inflammatory markers, these proportions increased to 48% and 27% respectively. All infants with abnormal inflammatory markers received these interventions. Using the AAP algorithm, 51% of patients would have been eligible for observation without LP or antibiotics. Two cases of bacteraemia were identified, both with abnormal inflammatory markers. Most infants were observed for 48 h (77%), with smaller proportions observed for 36 h (16%) and 24 h (7%).</p><p><strong>Conclusions: </strong>Clinicians frequently perform a more limited septic evaluation in 22- to 28-day-old infants when inflammatory markers are normal. A revised approach to fever in this age group could reduce unnecessary LP and antibiotic use by up to 50%.</p>","PeriodicalId":16648,"journal":{"name":"Journal of paediatrics and child health","volume":" ","pages":""},"PeriodicalIF":1.6,"publicationDate":"2025-03-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143557133","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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