Journal of paediatrics and child health最新文献_第3页

Time to positivity of blood cultures in paediatric patients. 儿科病人血液培养阳性的时间。

IF 1.6 4区医学

Journal of paediatrics and child health Pub Date : 2024-10-23 DOI: 10.1111/jpc.16707

Catrin Kar Yee Kong, Natalie Woon Hui Tan, Karen Donceras Nadua, Kai-Qian Kam, Jiahui Li, Koh Cheng Thoon, Chee Fu Yung, Matthias Maiwald, Chia Yin Chong

{"title":"Time to positivity of blood cultures in paediatric patients.","authors":"Catrin Kar Yee Kong, Natalie Woon Hui Tan, Karen Donceras Nadua, Kai-Qian Kam, Jiahui Li, Koh Cheng Thoon, Chee Fu Yung, Matthias Maiwald, Chia Yin Chong","doi":"10.1111/jpc.16707","DOIUrl":"https://doi.org/10.1111/jpc.16707","url":null,"abstract":"Aim: Continuous monitoring of blood culture (BC) systems allows rapid detection of microbial growth. We aimed to determine differences in time to positivity (TTP) in BACTEC BC between organisms and whether a 36-h period was sufficient to detect all relevant pathogenic bacteria for children admitted to a tertiary care paediatric hospital.Methods: This was a retrospective audit of positive aerobic (AE) and anaerobic (AN) BC from paediatric inpatients with available TTP from 1 August 2016 to 2 January 2019. First positive BC per bacteraemia episode was analysed.Results: Overall, 649 BC were positive, of which 480 first positive BC were analysed: 246 AE (51.3%) only, 216 paired (45%) (108 AE and 108 AN) and 18 AN (3.8%) only. There were 372 episodes of bacteraemia in 340 patients. Median age was 19 months (interquartile range (IQR): 1.25-60). Median TTP for AE and AN cultures was 13.20 (IQR: 9.84-18.48) and 13.92 h (IQR: 10.32-17.04), respectively. Organisms were GNR 49.7%, GPC 29.6%, contaminants 14.5%, mixed 3.0%, other 2.4% and yeast 0.8%. Streptococcus agalactiae had the fastest median TTP in AE and AN cultures, followed by Escherichia coli (AE 8.88 vs. 10.20 h). For paired AE and AN cultures, TTP was faster for AE versus AN cultures (13.36 vs. 14.52 h, P = 0.001). A 36-h cut-off time captured 97.7% AE BC and 99.1% AN BC with pathogens, and 86.5% AE BC and 91.7% AN BC with contaminants, respectively.Conclusions: GNR were the commonest pathogens in paediatric BC and faster growth was detected in AE versus AN cultures. By 36 h, >97.7% of BC were positive for pathogens versus 86.5% for contaminants.","PeriodicalId":16648,"journal":{"name":"Journal of paediatrics and child health","volume":" ","pages":""},"PeriodicalIF":1.6,"publicationDate":"2024-10-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142502378","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Paediatric meningococcal septicaemia: A rehabilitation case study highlighting allied health team work to optimise recovery within a tertiary healthcare setting. 儿科脑膜炎球菌败血症：一项康复案例研究，突出了联合医疗团队在三级医疗机构中优化康复的工作。

IF 1.6 4区医学

Journal of paediatrics and child health Pub Date : 2024-10-18 DOI: 10.1111/jpc.16706

Susan Taylor, Karen Twyford, Jodie Mazzucchelli, Penny Myers, Chelsea Cocking, Noula Gibson

引用次数: 0

Application of WINROP to predict severe retinopathy of prematurity in a multi-ethnic cohort in Singapore. 应用 WINROP 预测新加坡多种族队列中的严重早产儿视网膜病变。

IF 1.6 4区医学

Journal of paediatrics and child health Pub Date : 2024-10-17 DOI: 10.1111/jpc.16699

Kok Wooi Teoh, Sudarshan Seshasai, Mary Grace Sy Tan, Ng Wei Yan, Varsha Atul Shah, Alvin Ngeow Jia Hao

{"title":"Application of WINROP to predict severe retinopathy of prematurity in a multi-ethnic cohort in Singapore.","authors":"Kok Wooi Teoh, Sudarshan Seshasai, Mary Grace Sy Tan, Ng Wei Yan, Varsha Atul Shah, Alvin Ngeow Jia Hao","doi":"10.1111/jpc.16699","DOIUrl":"https://doi.org/10.1111/jpc.16699","url":null,"abstract":"Aim: To investigate the validity of WINROP use in multi-ethnic population in a tertiary centre in Singapore.Methods: Birth weight, gestational age, and weekly weight measurements of four hundred two preterm infants (<32 weeks gestation) born between year 2011 and 2019 were entered into WINROP algorithm. Based on their weekly weight gain, WINROP algorithm would signal an alarm if the infant is at risk for type 1 ROP requiring treatment. The WINROP result is then compared with the ophthalmological findings. All the infants were screened based on the hospital ROP screening protocol. The negative predictive value, positive predictive value, sensitivity and specificity were calculated.Results: Among all the infants enrolled, 31 infants developed type 1 ROP. WINROP successfully signalled 23 out of 31 correctly. The calculated sensitivity was 74.2 % and specificity was 48.0 %. The positive predictive value was 10.6% and negative predictive value was 95.7%.Conclusions: Our study showed that when WINROP is applied to our multi-ethnic population, it has a moderate sensitivity of 74.2% and a high predictive negative value of 95.7%. We would not recommend it to be used a solitary screening method but it can be used to better risk stratify preterm infants at risk of type 1 ROP, particularly in resource limited settings.","PeriodicalId":16648,"journal":{"name":"Journal of paediatrics and child health","volume":" ","pages":""},"PeriodicalIF":1.6,"publicationDate":"2024-10-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142468202","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Letter to the Editor. 致编辑的信

IF 1.6 4区医学

Journal of paediatrics and child health Pub Date : 2024-10-17 DOI: 10.1111/jpc.16700

Jack Ho, Lena Lim, Leonardo Bruzze, Ailsa Marshall, Amelia Christie, Sandeep Kaur, Nghi Bui, Gillian Burke, Sharon Youde, Kim Ramjan, Amy Wanaguru, Ohn Nyunt, Charles Verge, Shihab Hameed

引用次数: 0

Pre-referral ultrasound for cryptorchidism: Still common, still not necessary. 隐睾症转诊前超声检查：仍然常见，仍然没有必要。

IF 1.6 4区医学

Journal of paediatrics and child health Pub Date : 2024-10-17 DOI: 10.1111/jpc.16689

Grace E Boyd, Bhaveshkumar Patel, Craig A McBride

{"title":"Pre-referral ultrasound for cryptorchidism: Still common, still not necessary.","authors":"Grace E Boyd, Bhaveshkumar Patel, Craig A McBride","doi":"10.1111/jpc.16689","DOIUrl":"https://doi.org/10.1111/jpc.16689","url":null,"abstract":"Aim: Evidence-based guidelines do not recommend imaging in cryptorchidism, but anecdotally most referrals include an ultrasound report. We aimed to assess the frequency, utility and burden of imaging in children referred with presumptive disorders of testicular descent, and to assess trends over a 7-year period before and after local and international guidelines have been introduced.Methods: This was a prospective cohort study of children referred to the Queensland Children's Hospital for anomalies of testicular descent between 2015-2017 and 2023-2024. Data were collected regarding demographics, referral details, imaging performed and surgical diagnosis.Results: A total of 268 children were recruited. Ultrasound frequency has not significantly changed over time (72.8%, 2015-2017; 63.6% 2023-2024; P = 0.11). Currently, 17.6% of families are charged, and 31.9% need to take time off work, for the ultrasound. This is a significant increase from the 2015-2017 cohort. Parents report concern and anxiety, and find it traumatic for their child. Following review, the majority (65.7%) had physiologically normal testes, while 4.9% and 22.4% were diagnosed with bilateral or unilateral cryptorchidism, respectively, and 7.0% had other diagnoses. Ultrasound was concordant with the surgical diagnosis in 25.0% (2015-2017) and 30.7% (2023-2024). Ultrasound did not contribute to diagnosis nor management in any patient.Conclusions: Despite international and local guidelines, cryptorchid children continue to undergo ultrasound prior to referral. Such ultrasounds do not provide utility, or value for cost. We recommend avoiding their routine use for suspicion of testicular maldescent and working together to improve strategies for translating evidence-based guidelines into clinical practice.","PeriodicalId":16648,"journal":{"name":"Journal of paediatrics and child health","volume":" ","pages":""},"PeriodicalIF":1.6,"publicationDate":"2024-10-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142468212","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Evaluating vitamin D status in Chinese pre-school children using dried blood spots coupled with liquid chromatograph coupled with mass spectrometer. 利用干血斑和液相色谱-质谱联用仪评估中国学龄前儿童的维生素 D 状态。

IF 1.6 4区医学

Journal of paediatrics and child health Pub Date : 2024-10-16 DOI: 10.1111/jpc.16698

Zhenxuan Zhan, Fan Quan, Ning Zhao, Lijun Mai, Zhen Li, Yudong Li, Ting Sun, Xuan Zeng

{"title":"Evaluating vitamin D status in Chinese pre-school children using dried blood spots coupled with liquid chromatograph coupled with mass spectrometer.","authors":"Zhenxuan Zhan, Fan Quan, Ning Zhao, Lijun Mai, Zhen Li, Yudong Li, Ting Sun, Xuan Zeng","doi":"10.1111/jpc.16698","DOIUrl":"https://doi.org/10.1111/jpc.16698","url":null,"abstract":"Aim: Vitamin D is an essential micronutrient for multiple physiological processes, and its deficiency remains a world-wide public health problem that cannot be ignored. Dried blood spot (DBS) is a convenient tool in large-scale epidemiological studies, but its application in evaluating vitamin D status in Chinese population is still scarce. Herein, we aimed to determine the vitamin D status in Chinese pre-school children using DBS coupled with LC-MS/MS method.Methods: We first developed a sensitive and reliable method for the determination of 25-hydroxyvitamin D (25(OH)D) in DBS samples using an ultra-high-performance liquid chromatograph coupled with triple quadrupole mass spectrometer (UHPLC-QQQ-MS/MS). Next, we conducted a pilot study to compare the 25(OH)D concentration in DBS and serum samples. Finally, the assay method was used to evaluate vitamin D status in Chinese pre-school children.Results: The present method was validated to be reliable and robust for the determination of 25(OH)D in DBS samples. Comparable consistency was observed between the 25(OH)D concentration in DBS and serum samples. A total of 3826 DBS samples collected from children aged 1-7 years were determined. The median concentration of 25(OH)D was 19.57 ng/mL (interquartile range 14.73-24.36 ng/mL), and decreased from 1 to 7 years of age. In addition, 13.51% of male children and 15.12% female children are found to be deficient in 25(OH)D.Conclusions: DBS coupled with LC-MS/MS is a feasible strategy to evaluate vitamin D status in epidemiological studies. And vitamin D deficiency remains a common health problem in Chinese pre-school children.","PeriodicalId":16648,"journal":{"name":"Journal of paediatrics and child health","volume":" ","pages":""},"PeriodicalIF":1.6,"publicationDate":"2024-10-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142468205","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Impact of visitation restrictions in neonatal intensive care units during the COVID-19 pandemic on parents in northern Hokkaido, Japan. COVID-19 大流行期间新生儿重症监护室探视限制对日本北海道北部父母的影响。

IF 1.6 4区医学

Journal of paediatrics and child health Pub Date : 2024-10-16 DOI: 10.1111/jpc.16697

Ken Nagaya, Toshio Okamoto, Mitsumaro Nii, Aiko Aoyama-Hashimoto, Tatsutoshi Sugiyama, Kenta Takahashi, Takashi Sato, Masaru Shirai

{"title":"Impact of visitation restrictions in neonatal intensive care units during the COVID-19 pandemic on parents in northern Hokkaido, Japan.","authors":"Ken Nagaya, Toshio Okamoto, Mitsumaro Nii, Aiko Aoyama-Hashimoto, Tatsutoshi Sugiyama, Kenta Takahashi, Takashi Sato, Masaru Shirai","doi":"10.1111/jpc.16697","DOIUrl":"https://doi.org/10.1111/jpc.16697","url":null,"abstract":"Aim: Medical institutions restricted visitation to neonatal intensive care units (NICUs) during the coronavirus disease (COVID-19) pandemic. Therefore, this study aimed to investigate the impact of COVID-19 NICU visitor restrictions on parents.Methods: We conducted a questionnaire of 378 parents of infants who were hospitalised for more than 1 week at two NICUs in our area and discharged between 1 April 2020 and 31 March 2022. While the visiting rules for NICUs during this period varied depending on the phase of the COVID-19 epidemic, generally, only parents were allowed to visit the NICUs for a few hours daily.Results: A total of 157 parents (A University Hospital (AMUH), n = 79; AK General Hospital (AKGH), n = 78) responded to the survey (41.3% response rate), with 40% stating that their emotions towards their infants were affected by restrictions due to the COVID-19 pandemic. Parents' feelings towards their infants were influenced by mode of delivery, parity, duration of hospitalisation and opportunities to visit the NICU. More than 70% of respondents felt stressed due to COVID-19 restrictions, and anxiety and emotional stress related to visitor restrictions were significantly affected by the number and duration of visits and allowability of family member visits. Parents felt that the restrictions had a negative impact on breastfeeding, overall infant care and infant-family bonding.Conclusion: As parents felt an impact on the bond with their infant during visitation restrictions, it is essential for facilities to implement measures to protect infant-family bonding during potential future pandemics.","PeriodicalId":16648,"journal":{"name":"Journal of paediatrics and child health","volume":" ","pages":""},"PeriodicalIF":1.6,"publicationDate":"2024-10-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142468208","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Omenn syndrome: A rare manifestation of severe combined immunodeficiency masquerading as drug reaction with eosinophilia and systemic symptoms. 奥门综合征：一种罕见的严重联合免疫缺陷表现，伪装成药物反应，伴有嗜酸性粒细胞增多和全身症状。

IF 1.6 4区医学

Journal of paediatrics and child health Pub Date : 2024-10-16 DOI: 10.1111/jpc.16702

Elizabeth M Forbes, Peter B McNaughton

引用次数: 0

The escalator. 自动扶梯

IF 1.6 4区医学

Journal of paediatrics and child health Pub Date : 2024-10-15 DOI: 10.1111/jpc.16685

Mick O'Keeffe

引用次数: 0

Global developmental delay: A global misnomer. 全球发育迟缓：一个全球性的误称。

IF 1.6 4区医学

Journal of paediatrics and child health Pub Date : 2024-10-15 DOI: 10.1111/jpc.16701

Giuliana Antolovich, Monica S Cooper

引用次数: 0