Journal of Gastroenterology & Hepatology Reports最新文献

{"title":"A Combined Treatment of Life-threatening and Difficult to Treat Bleeding Gastro-oesophageal Varices in a Patient with Cirrhosis and Portal Cavernomatosis","authors":"Simone Di Cola","doi":"10.47363/jghr/2022(3)146","DOIUrl":"https://doi.org/10.47363/jghr/2022(3)146","url":null,"abstract":"Balloon-occluded retrograde transvenous obliteration (BRTO) is an endovascular secondary prophylactic approach to gastroesophageal variceal (GOV) bleeding. However, standard primary prophylaxis is olten inef-fective and GOV bleeding is more severe than esophageal variceal (EV) bleeding. Portal vein thrombosis and its evolution to cavernomatosis are common complications of cirrhosis. There are no data in the literature on the safety of BRTO in patients with portal cavernomatosis and on the risk of excessively increasing portal hypertension in patients with esophageal varices at risk of bleeding. Portal cavernomatosis is a relative con-traindication to TIPS placement. Furthermore, in our knowledge there are no great experiences on the com-bined use of BRTO and TIPS and no information in patients with portal cavernomatosis.","PeriodicalId":166372,"journal":{"name":"Journal of Gastroenterology & Hepatology Reports","volume":"36 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"125047422","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Hepatorenal Syndrome in Cirrhosis of Liver at Tertiary Care Centre of Nepal","authors":"J. B.","doi":"10.47363/jghr/2022(3)147","DOIUrl":"https://doi.org/10.47363/jghr/2022(3)147","url":null,"abstract":"Introduction: Hepatorenal syndrome (HRS) is the development of renal failure in patients with severe liver disease. Acute renal dysfunction including HRS is commonly occurs in hospitalized patients with cirrhosis. It is observed that morbidity and mortality remain high once the syndrome is established. This syndrome is usually managed with different vasoconstrictors and albumin with variable outcome but ultimate treatment is the liver transplantation. Methodology: This was a hospital based descriptive study carried out in Liver unit of Bir hospital. The cases were collected from (April, 2015 to March, 2016), admitted in Liver unit, Bir Hospital, Kathmandu, Nepal. One hundred and thirty eight cases were randomly selected from 450 patients admitted in the hospital.Patients of HRS were selected and treated with one of the treatment regime from 1. Albumin and Nor adrenaline group 2. Albumin and Dopamine group 3. Dopamine only 4.Terlipressin and Albumin groups. Patients with No HRS group were treated according to standard protocol of the institute.","PeriodicalId":166372,"journal":{"name":"Journal of Gastroenterology & Hepatology Reports","volume":"223 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"131960386","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Presentation and Management of Gastrointestinal Stromal Tumour (Gist) Among Sudanese Patients from April 2015 to April 2019","authors":"Mutaz Ogeal Osman","doi":"10.47363/jghr/2022(3)145","DOIUrl":"https://doi.org/10.47363/jghr/2022(3)145","url":null,"abstract":"Background: Gastrointestinal stromal tumour is one of the common alimentary tract tumour and it have different anatomical site of occurrence; there are international data that are common to occur in the stomach but no local data about the common site in Sudanese patients and the presentation. Objective: To asses presentation and management of gastrointestinal stromal tumour among Sudanese patients","PeriodicalId":166372,"journal":{"name":"Journal of Gastroenterology & Hepatology Reports","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-09-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"124109749","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Hypoglycaemia due to Autoimmunity","authors":"A. Ekladious","doi":"10.47363/jghr/2022(3)141","DOIUrl":"https://doi.org/10.47363/jghr/2022(3)141","url":null,"abstract":"Hirata disease is an insulin autoimmune disease characterized by non-exogenous hyper insulinemic postprandial hypoglycemia due to elevated insulin autoimmune antibodies (IAS), with no exogenous insulin and no pathological abnormalities of pancreatic islets cells, the diagnosis is often missed due to the rarity of the disease, failure to diagnose Hirata disease in a timely manner often results in exposing the patients to unnecessary investigation and surgical procedures.","PeriodicalId":166372,"journal":{"name":"Journal of Gastroenterology & Hepatology Reports","volume":"3 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-09-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"114882001","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Spontaneous Perforation of Meckel’s Diverticulum Presenting as a Rare Cause of Acute Abdomen: A Case Report","authors":"João Kleber de Gentile","doi":"10.47363/jghr/2022(3)142","DOIUrl":"https://doi.org/10.47363/jghr/2022(3)142","url":null,"abstract":"Meckel’s diverticulum (MD) is the most common congenital abnormality of the gastrointestinal tract, most likely to be found at the antimesenteric side of the distal ileum. The majority of patients remain asymptomatic however symptoms such as obstruction, perforation, inflammation and gastrointestinal hemorrhage can occur due to complications, which have an extensive variety of clinical and imaging manifestations. Accordingly, it is important to consider Meckel’s diverticulum as a differential diagnosis in patients presenting with acute abdomen. The treatment of complicated MD is surgery but there is no clear recommendation yet for incidentally detected cases.","PeriodicalId":166372,"journal":{"name":"Journal of Gastroenterology & Hepatology Reports","volume":"76 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-09-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"127573794","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Evaluation of the Ripasa Score: A New Scoring System for the Diagnosis of Acute Appendicitis in East of Sudan (Single Center Experience from January to June 2022)","authors":"Mutaz Ogeal Osman","doi":"10.47363/jghr/2022(3)144","DOIUrl":"https://doi.org/10.47363/jghr/2022(3)144","url":null,"abstract":"Introduction: Acute appendicitis is one of the most common surgical emergencies. Despite being a common problem, it remains a difficult diagnosis to establish, particularly among the young, the elderly and females of reproductive age the study aimed to compare the efficacy of RIPASA score in the diagnosis of acute appendicitis. We recently developed a scoring system for diagnosis of acute appendicitis. This study prospectively evaluates the Raja Isteri Pengiran Anak Saleha Appendicitis (RIPASA) score for the diagnosis of acute appendicitis in patients presenting to the Accident and Emergency department or the Surgical wards with right iliac fossa pain. Materials and Methods: From January to June 2022 consecutive patients presenting to the Accident and Emergency department or the surgical wards with right iliac fossa pain were recruited for the study. The RIPASA score was applied but the decision for radiological investigations or emergency appendicectomy was made based on clinical judgment.","PeriodicalId":166372,"journal":{"name":"Journal of Gastroenterology & Hepatology Reports","volume":"137 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-09-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"116411188","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Dunbar Syndrome Treated by Laparoscopic Surgery","authors":"Mariana Mussalem Santos","doi":"10.47363/jghr/2022(3)140","DOIUrl":"https://doi.org/10.47363/jghr/2022(3)140","url":null,"abstract":"Median arcuate ligament syndrome (MALS) or Dunbar syndrome is a rare condition resulting from compression of the celiac trunk by the median ligament at the level of the diaphragmatic crus. Abdominal tomography contributes to the diagnosis by demonstrating the level of obstruction and the presence of collateral arterial circulation in the gastroduodenal region, typical of the disease in chronic cases. The therapeutic options, although few, find in the laparoscopic surgical treatment the best option for releasing the muscle fibers in the arcuate ligament region. We report a rare case of a 38-year-old woman diagnosed with MALS successfully treated laparoscopically.","PeriodicalId":166372,"journal":{"name":"Journal of Gastroenterology & Hepatology Reports","volume":"21 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-09-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"133882272","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"High-Value-Care Case Based Management in Pediatric Wilson Disease","authors":"Arian Karimi Rouzbehani","doi":"10.47363/jghr/2022(3)143","DOIUrl":"https://doi.org/10.47363/jghr/2022(3)143","url":null,"abstract":"High-value care (HVC) is a term used for providing the best care possible for patients while simultaneously decreasing unnecessary expenses. HVC is a good instance of striking a balance between cost and benefit. Principles of value-based health care provide physicians with the necessary knowledge, tools, and strategies to improve the process of clinical reasoning. In this article, we present a case of Wilson’s disease in an 8-year-old boy as a clinical example of the impact of HVC on clinical decision-making and clinical reasoning","PeriodicalId":166372,"journal":{"name":"Journal of Gastroenterology & Hepatology Reports","volume":"5 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-09-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"127612860","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Renewed Interest in Cholera Control","authors":"S. Bhattacharya","doi":"10.47363/jghr/2022(3)133","DOIUrl":"https://doi.org/10.47363/jghr/2022(3)133","url":null,"abstract":"Cholera is an ancient disease of significant public health importance accounting for approximately 1.3-4 million cases worldwide and about 21000–143,000 deaths. Cholera is endemic in many developing countries where sanitation is poor and lack in safe water. The disease has the potential to cause large-scale epidemics and pandemics. The ongoing seventh pandemic has spread to more than 100 countries since its origin in 1961 in Indonesia. Travellers from developed countries travelling to cholera endemic areas are at higher risk of getting cholera. Oral rehydration therapy (ORT) has revolutionized the treatment of cholera and causes reduction of mortality. ORT has saved the lives of millions of children all over the world and is considered the single most significant discovery in medicine of the century. Effective oral cholera vaccines have been developed and are being used but not to its full potential to control cholera. Since the disease burden due to cholera is huge and we have the tools to combat cholera, particularly reduce mortality, it is imperative that the global communities should embark on cholera control as an urgent priority of human health. Cholera control should be viewed as a poverty alleviation programme for the marginalised population. The current pandemic of COVID-19 overwhelmed the economy and healthcare systems so much so that the health authorities undermined the cholera control measures even during ongoing epidemics of cholera. The World Health Organization (WHO) has reframed the strategy with renewed interest on cholera control with a target of reducing the mortality from cholera by 90 percent by 2030. Member countries should mobilize enough funds for the programme and actively implement it. Improvement of sanitation and safe water for all should continue as long-term solution for combating the menace of cholera.","PeriodicalId":166372,"journal":{"name":"Journal of Gastroenterology & Hepatology Reports","volume":"27 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-06-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"129281547","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Study of Gastrointestinal Causes of Death: A 5-Year Autopsy Based Study","authors":"S. Adidam, Varindra Rakhar, C. R. Adidam Venkata","doi":"10.47363/jghr/2022(3)137","DOIUrl":"https://doi.org/10.47363/jghr/2022(3)137","url":null,"abstract":"Introduction: Gastrointestinal disorders (GI) including hepatobiliary-pancreatic (HBP) diseases are a cause for significant morbidity and mortality. Mortality due to nonmalignant disorders are often diagnosed but are less studied. Limited autopsy-based studies have been conducted on gastrointestinal causes of death despite gastrointestinal and hepato-biliary-pancreatic diseases being one of the important causes for morbidity and mortality. Autopsy is still considered a valuable tool in reliably determining the underlying pathology and cause of death. This study of gastrointestinal causes of death was conducted to evaluate and understand its impact. Methods: This is a 5-year retrospective autopsy-based study for the period August 2016 to July 2021. Data was collected from autopsy request forms, patients’ hospital records and autopsy reports, which included age, gender, ethnicity, salient clinical features, key autopsy findings and the cause of death. Results: During the 5-year period, a total of 3435 autopsies were performed, out of which 294 cases were found to have gastrointestinal-hepato-biliarypancreatic (GIHBP) disorders as the cause of death, contributing to 8.6%. This accounts for the third leading cause of death. The main causes of death were gastrointestinal bleeding (GIB) (26%), perforation of a viscus organ and peritonitis (23%), hepato-biliary-pancreatic disease (17%), ischemic bowel changes (13.6%), neoplastic disease (11.6%) and others. Majority of patients were males and of African ethnicity. Patients aged above 40 years accounted for 83% of the deaths. Abdominal pain was the most common presenting symptom. Three leading autopsy findings include gastrointestinal bleeding, ascites, perforation and peritonitis. Conclusion: GIHBP disorders are the third leading cause of death. GI bleeding, non-traumatic perforation and peritonitis are identified as significant mechanisms of death. Autopsy still plays an important role in reliably determining the cause of death. Prompt diagnosis and appropriate management may decrease mortality. This study augments the limited body of literature and provides insight into gastrointestinal causes of death.","PeriodicalId":166372,"journal":{"name":"Journal of Gastroenterology & Hepatology Reports","volume":"7 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-06-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"133120881","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}