{"title":"A Pharmacological and Critical Review of Caffeine and Alpha-Lipoic Acid for Burning Mouth Syndrome","authors":"Takahiko Nagamine","doi":"10.1111/joor.70126","DOIUrl":"10.1111/joor.70126","url":null,"abstract":"<p>Clinical trials combining caffeine and 5-ALA for British Meditational Syndrome (BMS) have shown preliminary signs of short-term symptom relief. These substances, which are not traditional painkillers, act through unique, non-traditional mechanisms that are usefully understood through mechanism-based nomenclature.\u0000 <figure>\u0000 <div><picture>\u0000 <source></source></picture><p></p>\u0000 </div>\u0000 </figure></p>","PeriodicalId":16605,"journal":{"name":"Journal of oral rehabilitation","volume":"53 2","pages":"603-605"},"PeriodicalIF":4.0,"publicationDate":"2025-12-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145743002","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Lorena Tavares Gama, Mariana Marinho Davino de Medeiros, Yuri Wanderley Cavalcanti, Mario Augusto Brondani, Renata Cunha Matheus Rodrigues Garcia
{"title":"Masticatory Function in Elderly Individuals Living in Long-Term Care Facilities in Brazil: Associations Between Objective and Subjective Measurements","authors":"Lorena Tavares Gama, Mariana Marinho Davino de Medeiros, Yuri Wanderley Cavalcanti, Mario Augusto Brondani, Renata Cunha Matheus Rodrigues Garcia","doi":"10.1111/joor.70133","DOIUrl":"10.1111/joor.70133","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Background</h3>\u0000 \u0000 <p>Although objective and subjective masticatory function measures may correlate, associated oral health–related factors may differ, highlighting the need for comprehensive assessment to support tailored care in long-term care facilities (LTCFs).</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Objective</h3>\u0000 \u0000 <p>To investigate the association between objective and subjective masticatory function and the oral health status of older LTCF residents in Brazil.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Materials and Methods</h3>\u0000 \u0000 <p>This cross-sectional study included 187 residents (mean age = 78.7 ± 9.2 years) from nine LTCFs. Masticatory function was evaluated objectively (bi-coloured chewing gum) and subjectively (‘Do you have trouble biting or chewing any kind of food?’). Oral health status was assessed by self-perceived oral health, the number of natural teeth and posterior occluding pairs (POPs), xerostomia and dental prosthesis requirement. Data were analysed using multiple regression (<i>α</i> = 0.05).</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>Objective and subjective masticatory function were associated (<i>p</i> < 0.001). Older age (<i>p</i> = 0.006), low number of natural teeth (<i>p</i> = 0.001) and POPs (<i>p</i> = 0.004) and the dental prosthesis requirement (<i>p</i> = 0.016) were associated with poorer objective masticatory function. Poor self-perceived oral health (<i>p</i> = 0.001), low number of POPs (<i>p</i> = 0.013), severe xerostomia symptoms (<i>p</i> = 0.001) and dental prosthesis requirement (<i>p</i> = 0.030) were associated with poor subjective masticatory function.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusion</h3>\u0000 \u0000 <p>Objective and subjective masticatory functions were associated and shared some common factors, number of POPs and the need for dental prostheses. However, objective measures (e.g., number of teeth) were linked to objective masticatory function, whereas self-perceived factors (e.g., perceived oral health and xerostomia) were associated with subjective masticatory function.</p>\u0000 </section>\u0000 </div>","PeriodicalId":16605,"journal":{"name":"Journal of oral rehabilitation","volume":"53 3","pages":"761-769"},"PeriodicalIF":4.0,"publicationDate":"2025-12-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12902196/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145723978","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Yoon-Jin Kim, Ji-Eun Kim, Choong-Ho Choi, Ki-Ho Chung
{"title":"Modified Relative Handgrip Strength and Tooth Loss: A Nationwide Study","authors":"Yoon-Jin Kim, Ji-Eun Kim, Choong-Ho Choi, Ki-Ho Chung","doi":"10.1111/joor.70135","DOIUrl":"10.1111/joor.70135","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Background</h3>\u0000 \u0000 <p>Handgrip strength (HGS) reflects overall muscular fitness and health. Although associations between absolute or BMI-adjusted HGS and systemic conditions have been studied, no research has examined its link to tooth loss using modified relative HGS indices from other anthropometric factors.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Objectives</h3>\u0000 \u0000 <p>This study aimed to investigate, for the first time, the association between tooth loss and various modified relative HGS indices using nationally representative data.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Methods</h3>\u0000 \u0000 <p>Using the 2014–2023 Korean National Health and Nutrition Examination Survey data (<i>n</i> = 52 206), relative HGS was calculated by adjusting dominant HGS with various body indices. Oral status was classified as functional (≥ 20 teeth) or reduced (< 20 teeth). Statistical analysis to assess associations and diagnostic accuracy was performed using the chi-square test, <i>t</i>-test, incidence rate ratio (IRR), and the receiver operating characteristic (ROC).</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>In the fully adjusted IRR analysis, waist circumference (WC)-based relative HGS showed the strongest inverse association with tooth loss (IRR = 0.505, 95% confidence interval [CI] = 0.388–0.656). The ROC analysis revealed that relative HGS indicators adjusted for WC, waist-to-height ratio (WHtR), and weight-adjusted waist index (WWI), which represent central adiposity, had the highest diagnostic accuracy for predicting tooth loss (area under the curve [AUC] = 0.6367, 0.6323, and 0.6316, respectively). Significant differences were observed in all HGS indicators based on the functional dentition criterion (<i>p</i> < 0.001).</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusion</h3>\u0000 \u0000 <p>WC-adjusted relative HGS showed the strongest inverse association with tooth loss, indicating its potential utility for early identification of high-risk individuals and informing multidisciplinary approaches to oral rehabilitation.</p>\u0000 </section>\u0000 </div>","PeriodicalId":16605,"journal":{"name":"Journal of oral rehabilitation","volume":"53 3","pages":"749-760"},"PeriodicalIF":4.0,"publicationDate":"2025-12-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145714728","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Eduardo Machado, Jessica Klöckner Knorst, Milton Maluly Filho, Monica Levy Andersen, Sergio Tufik, Cibele Dal Fabbro, Dalva Poyares
{"title":"Sleep Bruxism: Mapping Potential Direct and Indirect Risk Pathways in EPISONO Adult Population-Based Study","authors":"Eduardo Machado, Jessica Klöckner Knorst, Milton Maluly Filho, Monica Levy Andersen, Sergio Tufik, Cibele Dal Fabbro, Dalva Poyares","doi":"10.1111/joor.70128","DOIUrl":"10.1111/joor.70128","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Aim</h3>\u0000 \u0000 <p>To explore the direct and indirect pathways through which sociodemographic, psychological, behavioural, and clinical factors influence sleep bruxism (SB).</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Methods</h3>\u0000 \u0000 <p>This cross-sectional study was conducted with a sample of 686 adults (mean age of 50.1 years; 380 female and 306 male), from a total of 712 individuals from the Sao Paulo Epidemiological Sleep Study (EPISONO) follow performed in 2015. SB was assessed using self-report, overnight polysomnography (PSG-based), and combined methods. Sociodemographic, psychological, behavioural and clinical factors were assessed. Structural Equation Modelling was used to examine the pathways between potential risk factors and SB.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>From an initial sample of 1042, 712 returned for follow-up and 686 individuals were eligible based on the SB outcomes evaluated and having undergone PSG. The SB self-reported prevalence was 17.1%, 30.5% presented PSG-based SB and 7.4% in combination of methods (self-report+PSG). Sleep bruxism (assessed by all methods) was directly associated with higher levels of insomnia and younger age. Higher socioeconomic status was directly associated with self-reported SB, whereas PSG-based and self-report+PSG SB were associated with increased obstructive sleep apnea and smoking. Regarding indirect effects, elevated anxiety and depressive symptoms indirectly impacted all forms of SB via increased insomnia levels.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusions</h3>\u0000 \u0000 <p>Our findings highlight distinct and overlapping pathways of SB. Insomnia and younger age consistently predicted SB, while psychological factors indirectly impacted SB via insomnia. Demographic, behavioural, and clinical factors showed direct associations that varied according to the assessment method.</p>\u0000 </section>\u0000 </div>","PeriodicalId":16605,"journal":{"name":"Journal of oral rehabilitation","volume":"53 3","pages":"728-736"},"PeriodicalIF":4.0,"publicationDate":"2025-12-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12902199/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145708285","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Reconsidering Diagnostic Contexts and Validation Pathways for Dental-Dedicated MRI in Temporomandibular Joint Assessment","authors":"Carlos M. Ardila","doi":"10.1111/joor.70134","DOIUrl":"10.1111/joor.70134","url":null,"abstract":"","PeriodicalId":16605,"journal":{"name":"Journal of oral rehabilitation","volume":"53 2","pages":"606-607"},"PeriodicalIF":4.0,"publicationDate":"2025-12-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145708288","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Effects of Tongue Training Tasks on Intramuscular Activity Distribution: Evaluation Using Muscle Functional Magnetic Resonance Imaging","authors":"Masahiro Sato, Satoshi Yamaguchi, Yoshinori Hattori","doi":"10.1111/joor.70132","DOIUrl":"10.1111/joor.70132","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Background</h3>\u0000 \u0000 <p>From the perspective of site specificity, inducing muscle activity across a large area of the tongue through diversified tongue resistance training (TRT) may be an effective approach to improve tongue pressure (TP) and function. However, the distribution of muscle activity within the tongue during different TRT exercises remains unclear.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Objectives</h3>\u0000 \u0000 <p>To examine the hypothesis that muscle activity distribution within the tongue varies with TRT direction using muscle functional magnetic resonance imaging (mfMRI), and to clarify the relationship between these distributions and functional outcomes.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Methods</h3>\u0000 \u0000 <p>Twenty young volunteers were randomly assigned to either an elevation or a lateral 4 week TRT group. We performed mfMRI before (at rest) and immediately following each training task, before and after 4 weeks of TRT, and we measured maximal elevation, lateral TP, and oral diadochokinesis (ODK). A linear mixed-effects model was used to analyse the functional outcomes.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>After TRT, mfMRI revealed that elevation exercise activated the anterior tongue, including the origin of the genioglossus. Conversely, lateral exercise induced significant activity across a wider area extending to the tongue root. Post-training maximal elevation TP and overall ODK values were significantly higher in the elevation training group. No significant differences between groups were observed in post-training lateral TP.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusions</h3>\u0000 \u0000 <p>TRT direction changes the pattern of muscle activity in the tongue. This finding reveals qualitative aspects of TRT that cannot be evaluated by post-training TP alone, offering a new perspective for designing more effective rehabilitation programs.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Trial Registration</h3>\u0000 \u0000 <p>ClinicalTrials.gov identifier: UMIN000047658</p>\u0000 </section>\u0000 </div>","PeriodicalId":16605,"journal":{"name":"Journal of oral rehabilitation","volume":"53 3","pages":"737-748"},"PeriodicalIF":4.0,"publicationDate":"2025-12-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12902200/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145708231","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Adrian Ujin Yap, Wei Yang Wong, Wai Kin Yuen, Huann Lan Tan, Wan Nur Nafisah Wan Yahya, Rifqah Nordin
{"title":"Temporomandibular Disorder Pain and Somatic Symptoms in Migraine Patients: Idioms of Psychological Distress and Impact on Quality of Life","authors":"Adrian Ujin Yap, Wei Yang Wong, Wai Kin Yuen, Huann Lan Tan, Wan Nur Nafisah Wan Yahya, Rifqah Nordin","doi":"10.1111/joor.70127","DOIUrl":"10.1111/joor.70127","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Background</h3>\u0000 \u0000 <p>Studies on painful temporomandibular disorders (TMDs) and somatic symptoms in Southeast Asian migraine patients are lacking.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Objectives</h3>\u0000 \u0000 <p>This study investigated the prevalence of TMD pain and somatic symptoms in migraine patients, examining their relationships with pain characteristics, psychological distress, and quality of life (QOL). Additionally, it identified factors associated with moderate-to-severe distress, low QOL, and poor general health.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Methods</h3>\u0000 \u0000 <p>Participants were recruited from a neurology clinic, where migraines were diagnosed based on the ICHD-3 criteria. A trained interviewer administered a questionnaire comprising sociodemographics, migraine-specific information, the DC/TMD TMD pain screener (TPS), Graded Chronic Pain Scale (GCPS), Patient Health Questionnaires (PHQ-15/PHQ-4), and WHOQOL-BREF. Data were analysed employing Chi-square/Mann–Whitney <i>U</i> tests, Spearman's correlation, and logistic regression analysis (<i>α</i> = 0.05).</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>Among the 106 participants (mean age 45.3 years [SD = 14.0]), 31.1% experienced TMD pain, while 37.7% exhibited medium-to-high somatic symptoms. Individuals with comorbid migraine-TMD pain had a higher somatic symptom burden, distress, and poorer psychological/environmental QOL. Those with medium-to-high somatic symptoms reported more frequent migraines, greater pain intensity/disability, higher TMD pain propensity, elevated distress, and worse QOL in all domains. Somatic symptoms, but not TMD pain, were negatively and moderately correlated with general health, physical, and psychological QOL (<i>rs</i> = −0.41 to −0.53). Somatic symptoms (OR 1.34) and poor general health (OR 3.06) increased the odds of moderate-to-severe distress and low overall QOL, respectively.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusions</h3>\u0000 \u0000 <p>To effectively manage migraine patients, screening for TMDs and addressing somatic symptoms and general health are essential for reducing psychological distress and enhancing overall QOL.</p>\u0000 </section>\u0000 </div>","PeriodicalId":16605,"journal":{"name":"Journal of oral rehabilitation","volume":"53 3","pages":"714-727"},"PeriodicalIF":4.0,"publicationDate":"2025-12-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145708359","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Julian Bergen Smith, Kelsey Murray, Sarah H. Szynkiewicz, Peter A. Wasiuk, Meghan Dalton, Kirsty Thompson, Erin Kamarunas
{"title":"Reliability of Lingual Swallow Pressure Measurements in Healthy Older and Younger Adults","authors":"Julian Bergen Smith, Kelsey Murray, Sarah H. Szynkiewicz, Peter A. Wasiuk, Meghan Dalton, Kirsty Thompson, Erin Kamarunas","doi":"10.1111/joor.70125","DOIUrl":"10.1111/joor.70125","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Background</h3>\u0000 \u0000 <p>While maximum isometric pressure (MIP) is widely used in clinical and research settings, reduced lingual swallow pressure (LSP) has been observed in patients with dysphagia and in older healthy adults. However, limited evidence exists on the test–retest reliability of LSP across different bolus consistencies.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Objective</h3>\u0000 \u0000 <p>This study assessed the test–retest reliability of LSP measurements in both younger and older adults with healthy swallowing function to identify factors influencing oral swallowing pressure.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Methods</h3>\u0000 \u0000 <p>Participants 18–40 years (younger) and 60+ years (older) were assessed across four separate sessions. Bolus types included trials of saliva, thin, mildly thick and extremely thick water, randomised across study visits. Two-way mixed effects models with absolute agreement were used to calculate intraclass correlation coefficients (ICCs) and evaluate test–retest reliability of LSP for each swallow type (regular or effortful) and bolus type. Linear mixed effects regression modelling was used to examine the factors influencing LSP.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>A total of 51 participants were included. Test–retest reliability for LSP ranged from good to excellent across both groups (ICC = 0.79–0.98). Reliability was non-significantly higher in the older group (ICC = 0.96) and during effortful swallows (ICC = 0.94). Effort level significantly influenced LSP estimates, with effortful swallows producing about 1.83 times more lingual pressure than regular swallows. There were no significant effects of age, sex, or bolus type on LSP.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusion</h3>\u0000 \u0000 <p>These findings suggest that LSP measurements are reliable across measurement time points in nondysphagic participants, regardless of age, effort level, or bolus type. Only swallow effort level significantly influenced LSP estimates.</p>\u0000 </section>\u0000 </div>","PeriodicalId":16605,"journal":{"name":"Journal of oral rehabilitation","volume":"53 3","pages":"706-713"},"PeriodicalIF":4.0,"publicationDate":"2025-12-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145668567","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"The Relationship Between Oral Pain and Dietary Inflammatory Potential","authors":"Wanyu Wang, Qiang Luo, Jie Lin, Yue Li, Yang Ji","doi":"10.1111/joor.70121","DOIUrl":"10.1111/joor.70121","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Background</h3>\u0000 \u0000 <p>Chronic orofacial pain is a prevalent health issue with multifactorial aetiology, including potential contributions from diet-related inflammation. This study aimed to investigate the association between dietary inflammatory potential, assessed using the Dietary Inflammatory Index (DII), and self-reported oral pain among US adults.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Methods</h3>\u0000 \u0000 <p>We conducted a cross-sectional analysis using data from 23 802 participants in the National Health and Nutrition Examination Survey (NHANES) 2005–2018 who completed dietary recalls and responded to oral health questions. Oral pain was assessed by the frequency of self-reported aching in the mouth over the past year (NHANES variable OHQ620). Logistic regression models were used to assess the association between DII scores and oral pain. Subgroup analyses were conducted to identify populations most affected by a pro-inflammatory diet.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>Higher DII scores were significantly associated with an increased likelihood of experiencing oral pain. Participants in the highest DII quintile (27.19%) had a 19% higher risk of oral pain compared with those in the lowest quintile (20.69%), even after full adjustment (OR = 1.19, 95% CI: 1.03–1.37, <i>p</i> = 0.016). The association was particularly pronounced in younger individuals, females, non-Hispanic Whites, those with higher socio-economic status, normal BMI, a history of smoking, and relatively low alcohol consumption.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusion</h3>\u0000 \u0000 <p>These findings suggest that pro-inflammatory dietary patterns may exacerbate oral pain, potentially mediated through systemic inflammation or local mucosal irritation. While based on self-reported oral pain, the study highlights diet modification as a preventive strategy and calls for further research on specific pain subtypes.</p>\u0000 </section>\u0000 </div>","PeriodicalId":16605,"journal":{"name":"Journal of oral rehabilitation","volume":"53 3","pages":"695-705"},"PeriodicalIF":4.0,"publicationDate":"2025-11-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145634512","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Samilla Pontes Braga, Dyanne Medina Flores, Maria Emilia Servin Berden, Ana Claudia de Castro Ferreira Conti, Ambrosina Michelotti, Paulo César Rodrigues Conti
{"title":"Predictive Value of Diagnostic Methods for TMJ Hypermobility in the Associated Clinical and Functional Features of Temporomandibular Disorders: A Regression Study","authors":"Samilla Pontes Braga, Dyanne Medina Flores, Maria Emilia Servin Berden, Ana Claudia de Castro Ferreira Conti, Ambrosina Michelotti, Paulo César Rodrigues Conti","doi":"10.1111/joor.70120","DOIUrl":"10.1111/joor.70120","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Background</h3>\u0000 \u0000 <p>Joint hypermobility (JH), particularly at the temporomandibular joint (TMJ), has been proposed as a potential risk factor for temporomandibular disorders (TMD). However, its heterogeneous diagnostic approaches (clinical, anamnestic and imaging) limit the identification of reliable predictors of masticatory dysfunction and TMD outcomes.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Objectives</h3>\u0000 \u0000 <p>To determine which diagnostic methods for TMJ hypermobility best predict masticatory dysfunction and the clinical and functional repercussions of TMD.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Methods</h3>\u0000 \u0000 <p>This cross-sectional study included 126 adults recruited at the Bauru School of Dentistry. Participants were classified by Diagnostic Criteria for TMD (DC/TMD) into painful, dysfunction or combined groups, balanced by history of open-locking. Assessments comprised DC/TMD and ICOP examinations, symptom intensity on the visual analog scale (VAS), Beighton score, pressure pain thresholds, bite-force and fatigue tests, ultrasound of the TMJ capsule and masseter, CBCT-based condylar angle and validated measures of mandibular function and psychosocial factors.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>Bivariate analyses yielded associations, but multivariate models identified specific predictors. Open-locking independently predicted TMJ subluxation and higher joint instability. Increased condylar angle was associated with greater assisted opening and midline deviation. Unassisted opening predicted a larger condylar angle, greater pain-free opening and lateral condylar jump; assisted opening similarly predicted pain-free opening and lateral condylar jump. Lateral condylar jump independently predicted functional limitation in wide-opening tasks.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusion</h3>\u0000 \u0000 <p>Clinical, functional and imaging indicators of TMJ hypermobility capture distinct aspects of the condition. While open-locking, condylar angle and mouth-opening measures predict specific features, no single marker explains the full spectrum and TMJ hypermobility shows limited impact on overall TMD outcomes.</p>\u0000 </section>\u0000 </div>","PeriodicalId":16605,"journal":{"name":"Journal of oral rehabilitation","volume":"53 3","pages":"673-684"},"PeriodicalIF":4.0,"publicationDate":"2025-11-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12902195/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145634984","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}