Journal of opioid management最新文献

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Chronic opioid pain treatment converted to buprenorphine: A case series using a 3-step low-dose incremental dosing guideline 改用丁丙诺啡治疗慢性阿片类疼痛:使用三步低剂量递增剂量指南的病例系列
Journal of opioid management Pub Date : 2024-02-08 DOI: 10.5055/jom.0822
Gregory Acampora, Yi Zhang
{"title":"Chronic opioid pain treatment converted to buprenorphine: A case series using a 3-step low-dose incremental dosing guideline","authors":"Gregory Acampora, Yi Zhang","doi":"10.5055/jom.0822","DOIUrl":"https://doi.org/10.5055/jom.0822","url":null,"abstract":"We report a 30-case series from the Pain Management Center at the Massachusetts General Hospital where we have applied a guideline to convert chronic treatment for pain from full agonist opioids (FAO) to buprenorphine (BUP). Of the patients, 24 (80 percent) elected to continue BUP over FAO. Five conversions were stopped for side effects (fatigue) and/or lack of sufficient pain reduction. One patient elected not to participate on the day that the conversion was to begin. There were no major adverse events. We conclude that conversion to BUP should be considered as an alternative to treat patients on chronic opioids for pain.","PeriodicalId":16601,"journal":{"name":"Journal of opioid management","volume":" 86","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-02-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139792967","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Monitoring buprenorphine in patients on medication-assisted treatment 监测接受药物辅助治疗患者体内的丁丙诺啡
Journal of opioid management Pub Date : 2024-02-08 DOI: 10.5055/jom.0844
Amadeo Pesce, Katie Bollman, Kevin Krock, A. Cua, Keith Tran, Richard Thomas
{"title":"Monitoring buprenorphine in patients on medication-assisted treatment","authors":"Amadeo Pesce, Katie Bollman, Kevin Krock, A. Cua, Keith Tran, Richard Thomas","doi":"10.5055/jom.0844","DOIUrl":"https://doi.org/10.5055/jom.0844","url":null,"abstract":"Background: Buprenorphine is used for medication-assisted treatment of opioid dependence. \u0000Purpose: Monitoring of medication adherence involves testing of urine or oral fluid for the drug or its metabolite. \u0000Methods: Quantitative results using liquid chromatography tandem mass spectrometer testing defined the excretion pattern of the drug and its metabolites. \u0000Results: Frequency distribution curves of buprenorphine and norbuprenorphine describe the expected drug concentrations of patients on this medication. \u0000Conclusion: Urine and oral fluid drug testing can be used to monitor adherence in this population.","PeriodicalId":16601,"journal":{"name":"Journal of opioid management","volume":"347 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-02-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139852413","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Monitoring buprenorphine in patients on medication-assisted treatment 监测接受药物辅助治疗患者体内的丁丙诺啡
Journal of opioid management Pub Date : 2024-02-08 DOI: 10.5055/jom.0844
Amadeo Pesce, Katie Bollman, Kevin Krock, A. Cua, Keith Tran, Richard Thomas
{"title":"Monitoring buprenorphine in patients on medication-assisted treatment","authors":"Amadeo Pesce, Katie Bollman, Kevin Krock, A. Cua, Keith Tran, Richard Thomas","doi":"10.5055/jom.0844","DOIUrl":"https://doi.org/10.5055/jom.0844","url":null,"abstract":"Background: Buprenorphine is used for medication-assisted treatment of opioid dependence. \u0000Purpose: Monitoring of medication adherence involves testing of urine or oral fluid for the drug or its metabolite. \u0000Methods: Quantitative results using liquid chromatography tandem mass spectrometer testing defined the excretion pattern of the drug and its metabolites. \u0000Results: Frequency distribution curves of buprenorphine and norbuprenorphine describe the expected drug concentrations of patients on this medication. \u0000Conclusion: Urine and oral fluid drug testing can be used to monitor adherence in this population.","PeriodicalId":16601,"journal":{"name":"Journal of opioid management","volume":" 47","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-02-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139792356","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Cancer pain patients do not successfully handle opioids 癌症疼痛患者无法成功使用阿片类药物
Journal of opioid management Pub Date : 2024-02-08 DOI: 10.5055/jom.0849
Liel Kosev, Ofir Morag, Michelle Levitan, Itay Goor-Aryeh
{"title":"Cancer pain patients do not successfully handle opioids","authors":"Liel Kosev, Ofir Morag, Michelle Levitan, Itay Goor-Aryeh","doi":"10.5055/jom.0849","DOIUrl":"https://doi.org/10.5055/jom.0849","url":null,"abstract":"Objective: To evaluate patterns of opioid handling as well as their associated variables. \u0000Design: A transversal study. \u0000Setting: Institutional care. \u0000Participants: One hundred cancer pain patients aged 18 and above at diagnosis. \u0000Interventions: Open and dichotomous questions related to opioid handling and a depression-anxiety scale. \u0000Main outcome measure(s): The percentage of patients who properly handled opioids. \u0000Results: Of those surveyed, 42.1 percent of patients reported receiving opioid storage instructions, 73 percent did not receive any instructions related to proper opioid return/disposal, and 39 percent wrongly discarded them. The mean of patients with anxiety symptoms was 6.95 and of depression symptoms was 8.19. The Hebrew Version of the Hospital and Anxiety Scale total mean was 15.1. A significant relationship among patients with poor disposal habits was also found. \u0000Conclusions: Despite being aware of opioid's danger, patients' attitudes evidenced a poor safety responsibility. We believe that this might be due to the high percentage of disinformation and the influence of psychological symptoms on patients' decision-making.","PeriodicalId":16601,"journal":{"name":"Journal of opioid management","volume":" 30","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-02-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139792670","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Examining the relationship between head trauma and opioid use disorder: A systematic review 研究头部创伤与阿片类药物使用障碍之间的关系:系统回顾
Journal of opioid management Pub Date : 2024-02-08 DOI: 10.5055/jom.0846
Ali Abid, Mariam Paracha, Iva Çepele, Awais Paracha, Joseph Rueve, Akbar Fidahussain, Humza Rehman, Mckimmon Engelhardt, Noor Alyasiry, Zohair Siddiqui, Satvik Vasireddy, Bishal Kadariya, Nikitha B. Rao, Rohan Das, Wilson Rodriguez, Dixie Meyer
{"title":"Examining the relationship between head trauma and opioid use disorder: A systematic review","authors":"Ali Abid, Mariam Paracha, Iva Çepele, Awais Paracha, Joseph Rueve, Akbar Fidahussain, Humza Rehman, Mckimmon Engelhardt, Noor Alyasiry, Zohair Siddiqui, Satvik Vasireddy, Bishal Kadariya, Nikitha B. Rao, Rohan Das, Wilson Rodriguez, Dixie Meyer","doi":"10.5055/jom.0846","DOIUrl":"https://doi.org/10.5055/jom.0846","url":null,"abstract":"Objective: To examine recent literature and determine common clinical risk factors between antecedent traumatic brain injury (TBI) and the following development of opioid misuse and provide a framework for clinical identification of at-risk subjects and evaluate potential treatment implications within this association. \u0000Design: A comprehensive systematic literature search of PubMed was conducted for articles between 2000 and December 2022. Studies were included if the human participant had any head trauma exposure and any chronic opioid use or dependence. After eligibility criteria were applied, 16 studies were assessed for thematic trends. \u0000Results: Opioid use disorder (OUD) risks are heightened in cohorts with head trauma exposed to opioids while in the hospital, specifically with tramadol and oxycodone. Chronic pain was the most common predictor of long-term OUD, and continuous somatic symptoms associated with the TBI can lead to long-term opioid usage. Individuals who present with coexisting psychiatric conditions pose significantly more risk associated with a higher risk of long-term opioid use. \u0000Conclusion: Findings indicate that therapists and clinicians must consider a risk profile for persons with TBI and follow an integrated care approach to account for mental health, prior substance misuse, presenting somatic symptoms, and current medication regimen during evaluation.","PeriodicalId":16601,"journal":{"name":"Journal of opioid management","volume":" 50","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-02-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139792984","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Opioid stewardship program implementation in rural and critical access hospitals in Arizona 在亚利桑那州的农村医院和关键通道医院实施阿片类药物管理计划
Journal of opioid management Pub Date : 2024-02-08 DOI: 10.5055/jom.0842
Benjamin R. Brady, Bianca SantaMaria, Kathryn Tucker Ortiz y Pino, Bridget S. Murphy
{"title":"Opioid stewardship program implementation in rural and critical access hospitals in Arizona","authors":"Benjamin R. Brady, Bianca SantaMaria, Kathryn Tucker Ortiz y Pino, Bridget S. Murphy","doi":"10.5055/jom.0842","DOIUrl":"https://doi.org/10.5055/jom.0842","url":null,"abstract":"Objective: The objective of this study is to examine rural hospitals' status in implementing opioid stewardship program (OSP) elements and assess differences in implementation in emergency department (ED) and acute inpatient departments. \u0000Design: Health administrator survey to identify the number and type of OSP elements that each hospital has implemented. \u0000Setting: Arizona critical access hospitals (CAHs). \u0000Participants: ED and acute inpatient department heads at 17 Arizona CAHs (total of 34 assessments). \u0000Main outcome measures: Implementation of 11 OSP elements, by department (ED vs inpatient) and prevention orientation (primary vs tertiary). \u0000Results: The percentage of implemented elements ranged from 35 to 94 percent in EDs and 24 to 88 percent in acute care departments. Reviewing the prescription drug monitoring program database and offering alternatives to opioids were the most frequently implemented. Assessing opioid use disorder (OUD) and prescribing naloxone were among the least. The number of implemented elements tended to be uniform across departments. We found that CAHs implemented, on average, 67 percent of elements that prevent unnecessary opioid use and 54 percent of elements that treat OUD. \u0000Conclusions: Some OSP elements were in place in nearly every Arizona CAH, while others were present in only a quarter or a third of hospitals. To improve, more attention is needed to define and standardize OSPs. Equal priority should be given to preventing unnecessary opioid initiation and treating opioid misuse or OUD, as well as quality control strategies that provide an opportunity for continuous improvement. \u0000 ","PeriodicalId":16601,"journal":{"name":"Journal of opioid management","volume":" 67","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-02-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139793015","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Short-term healthcare resource utilization associated with receipt of CDC-informed opioid thresholds among commercially insured new chronic opioid users 商业保险新慢性阿片类药物使用者接受疾病预防控制中心提供的阿片类药物阈值后的短期医疗资源利用情况
Journal of opioid management Pub Date : 2024-02-08 DOI: 10.5055/jom.0848
Martin J. Calabrese, F. Shaya, Francis Palumbo, M. Mcpherson, Ester Villalonga-Olives, Z. Zafari, Ryan Mutter
{"title":"Short-term healthcare resource utilization associated with receipt of CDC-informed opioid thresholds among commercially insured new chronic opioid users","authors":"Martin J. Calabrese, F. Shaya, Francis Palumbo, M. Mcpherson, Ester Villalonga-Olives, Z. Zafari, Ryan Mutter","doi":"10.5055/jom.0848","DOIUrl":"https://doi.org/10.5055/jom.0848","url":null,"abstract":"Objective: To evaluate the impact of recent changes to the Centers for Disease Control and Prevention (CDC) morphine milligram equivalent (MME)/day threshold recommendations on healthcare utilization. \u0000Design: A retrospective cohort study of new chronic opioid users (NCOUs). \u0000Setting: Commercially insured plans across the United States using IQVIA PharMetrics® Plus for Academics database with new use between January 2014 and March 2015. \u0000Patients: NCOUs with ≥60-day coverage of opioids within a 90-day period with ≥30-day opioid-free period prior to the date of the first qualifying opioid prescription. \u0000Interventions: NCOU categorized by the CDC three-tiered risk-based average MME/day thresholds: low (>0 to <50), medium (≥50 to <90), and high (≥90). \u0000Main outcome measures: Multivariable logistic regression was used to calculate adjusted odds of incurring an acute care encounter (ACE) (all-cause and opioid related) between the thresholds (adjusted odds, 95 percent confidence interval). \u0000Results: In adjusted analyses, when compared to low threshold, there was no difference in the odds of all-cause ACE across the medium (1.01, 0.94-1.28) and high (1.01, 0.84-1.22) thresholds. When compared to low threshold, a statistically insignificant increase was observed when evaluating opioid-related ACE among medium (1.86, 0.86-4.02) and high (1.51, 0.65-3.52) thresholds. \u0000Conclusions: There was no difference in odds of an all-cause or opioid-related ACE associated with the thresholds. Early-intervention programs and policies exploring reduction of MME/day among NCOUs may not result in short-term reduction in all-cause or opioid-related ACEs. Further assessment of potential long-term reduction in ACEs among this cohort may be insightful. \u0000 ","PeriodicalId":16601,"journal":{"name":"Journal of opioid management","volume":" 24","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-02-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139793444","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Opioid stewardship program implementation in rural and critical access hospitals in Arizona 在亚利桑那州的农村医院和关键通道医院实施阿片类药物管理计划
Journal of opioid management Pub Date : 2024-02-08 DOI: 10.5055/jom.0842
Benjamin R. Brady, Bianca SantaMaria, Kathryn Tucker Ortiz y Pino, Bridget S. Murphy
{"title":"Opioid stewardship program implementation in rural and critical access hospitals in Arizona","authors":"Benjamin R. Brady, Bianca SantaMaria, Kathryn Tucker Ortiz y Pino, Bridget S. Murphy","doi":"10.5055/jom.0842","DOIUrl":"https://doi.org/10.5055/jom.0842","url":null,"abstract":"Objective: The objective of this study is to examine rural hospitals' status in implementing opioid stewardship program (OSP) elements and assess differences in implementation in emergency department (ED) and acute inpatient departments. \u0000Design: Health administrator survey to identify the number and type of OSP elements that each hospital has implemented. \u0000Setting: Arizona critical access hospitals (CAHs). \u0000Participants: ED and acute inpatient department heads at 17 Arizona CAHs (total of 34 assessments). \u0000Main outcome measures: Implementation of 11 OSP elements, by department (ED vs inpatient) and prevention orientation (primary vs tertiary). \u0000Results: The percentage of implemented elements ranged from 35 to 94 percent in EDs and 24 to 88 percent in acute care departments. Reviewing the prescription drug monitoring program database and offering alternatives to opioids were the most frequently implemented. Assessing opioid use disorder (OUD) and prescribing naloxone were among the least. The number of implemented elements tended to be uniform across departments. We found that CAHs implemented, on average, 67 percent of elements that prevent unnecessary opioid use and 54 percent of elements that treat OUD. \u0000Conclusions: Some OSP elements were in place in nearly every Arizona CAH, while others were present in only a quarter or a third of hospitals. To improve, more attention is needed to define and standardize OSPs. Equal priority should be given to preventing unnecessary opioid initiation and treating opioid misuse or OUD, as well as quality control strategies that provide an opportunity for continuous improvement. \u0000 ","PeriodicalId":16601,"journal":{"name":"Journal of opioid management","volume":"44 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-02-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139852759","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Chronic opioid pain treatment converted to buprenorphine: A case series using a 3-step low-dose incremental dosing guideline 改用丁丙诺啡治疗慢性阿片类疼痛:使用三步低剂量递增剂量指南的病例系列
Journal of opioid management Pub Date : 2024-02-08 DOI: 10.5055/jom.0822
Gregory Acampora, Yi Zhang
{"title":"Chronic opioid pain treatment converted to buprenorphine: A case series using a 3-step low-dose incremental dosing guideline","authors":"Gregory Acampora, Yi Zhang","doi":"10.5055/jom.0822","DOIUrl":"https://doi.org/10.5055/jom.0822","url":null,"abstract":"We report a 30-case series from the Pain Management Center at the Massachusetts General Hospital where we have applied a guideline to convert chronic treatment for pain from full agonist opioids (FAO) to buprenorphine (BUP). Of the patients, 24 (80 percent) elected to continue BUP over FAO. Five conversions were stopped for side effects (fatigue) and/or lack of sufficient pain reduction. One patient elected not to participate on the day that the conversion was to begin. There were no major adverse events. We conclude that conversion to BUP should be considered as an alternative to treat patients on chronic opioids for pain.","PeriodicalId":16601,"journal":{"name":"Journal of opioid management","volume":"4 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-02-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139852922","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Role of opioid use in gastrointestinal obstruction and perforation: A retrospective review 阿片类药物在胃肠道梗阻和穿孔中的作用:回顾性研究
Journal of opioid management Pub Date : 2024-02-08 DOI: 10.5055/jom.0850
Divya Bishnoi, Priyanka Sharma, A. K. Rathi
{"title":"Role of opioid use in gastrointestinal obstruction and perforation: A retrospective review","authors":"Divya Bishnoi, Priyanka Sharma, A. K. Rathi","doi":"10.5055/jom.0850","DOIUrl":"https://doi.org/10.5055/jom.0850","url":null,"abstract":"Introduction: Pain is one of the most common complaints that brings a patient to a hospital. For this, usually, the patient might have already consumed various types of pain killer combinations, either prescribed or over-the-counter. In some of these cases, a patient consumes these medicines unmonitored for a long time and then comes with complications, among which gastrointestinal tract obstruction and perforation are the most life threatening. \u0000Materials and methods: Case files from the Department of Surgery were retrieved and studied. Patients were contacted telephonically for details of drug abuse history. These were then further studied in detail. \u0000Results: Forty-eight (68 percent) patients out of a total of 78 had a history of drug abuse. The most commonly abused pain killer was a combination of anti-inflammatory and other salts, which was found in 22 (46 percent) patients, followed by tramadol, NSAIDs, opium, and alcohol (23, 17, 10, and 4 percent, respectively). These groups were comparable in socio-demographic details except in the mean age, occupation, and gender distribution, and the difference was significant (p < 0.01). The most common cause for starting to use any of the above-mentioned pain killer was persistent pain. The most common site of obstruction in drug abusers was the stomach (60 percent), followed by the small intestine (38 percent) and the large intestine (2 percent). \u0000Limitations: (1) This is an observational retrospective record review. (2) Records were studied in hospital settings, so results should be generalized cautiously. (3) Risk of recall bias is present. \u0000Conclusion: Pain killers should always be prescribed with caution and for a short duration. Alternative options for pain relief should be made available, and doctors should be trained. Drug abusers tend to have a gastrointestinal complication at an early age, which means they are prone to further complications and recurrence if the problem is not addressed on time.","PeriodicalId":16601,"journal":{"name":"Journal of opioid management","volume":"228 1-2","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-02-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139852424","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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