Opioid prescription patterns in a children's hospital from 2012 to 2016.

Q3 Medicine
Nicole Titze, Rishi Bhargava, Ara Jamasbi Montalvo, Gawon Shin, Campbell Belisle Haley, Soheil Saadat, Bharath Chakravarthy
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引用次数: 0

Abstract

Study objective: Pain management is a widely discussed topic, especially in the setting of the current opioid epidemic. Previous studies have shown that the use of opioids increased in the adult population. We aimed to look at the use of narcotic and non-narcotic pain medications at a large pediatric hospital to discern if patterns of pediatric pain management changed over time.

Methods: 58,402 analgesic prescriptions of patients 0-21 years of age were analyzed from May 2012 to November 2016. A logistic regression model was fitted to examine the association of age, sex, primary diagnosis, and the length of hospital stay with probability of opioid prescription.

Results: 36,560 patients aged 0-21 years (mean: 10.5, median: 11.0, and standard deviation (SD): 7.42) received analgesic pain medications. 21,847 (59.8 percent) patients were prescribed more than one analgesic. There was a male predominance in patients <15 years of age; however, in adolescents >16 years, females constituted 57.1 percent of patients. Data also showed a statistically significant reduction of opioid prescriptions from 2012 to 2016 (p < 0.001). Age and length of hospital stay were directly associated with opioid prescription (p < 0.001).

Conclusion: Data show that there is a decrease in overall opioid prescriptions among pediatric patients, which may be secondary to new Food and Drug Administration regulations and increased awareness of morbidity associated with opioid use. Not surprisingly, increased hospital stay and increase in age lead to more analgesic prescriptions. Further investigation is needed to determine the differences within opioid prescription patterns.

2012 年至 2016 年一家儿童医院的阿片类药物处方模式。
研究目的:疼痛管理是一个被广泛讨论的话题,尤其是在当前阿片类药物流行的背景下。以往的研究表明,阿片类药物的使用在成年人群中有所增加。我们旨在调查一家大型儿科医院麻醉性和非麻醉性止痛药物的使用情况,以了解儿科疼痛管理模式是否随着时间的推移而发生变化。方法:我们分析了 2012 年 5 月至 2016 年 11 月期间 0-21 岁患者的 58402 份镇痛处方。采用逻辑回归模型研究年龄、性别、主要诊断和住院时间与阿片类药物处方概率的关系:结果:36560 名 0-21 岁的患者(平均年龄:10.5 岁,中位数:10.5 岁)被处方阿片类药物:结果:36,560 名 0-21 岁的患者(平均值:10.5,中位数:11.0,标准偏差(±0.9))被处方阿片类药物:结果:36560 名 0-21 岁的患者(平均值:10.5,中位值:11.0,标准差(SD):7.42)接受了镇痛药物治疗。21,847 名患者(59.8%)服用了一种以上的镇痛药。16 岁患者中男性居多,女性占 57.1%。数据还显示,从2012年到2016年,阿片类药物的处方量出现了统计学意义上的显著减少(p < 0.001)。年龄和住院时间与阿片类药物处方直接相关(p < 0.001):数据显示,儿科患者的阿片类药物处方总量有所减少,这可能与食品药品管理局的新规定以及人们对阿片类药物使用相关发病率的认识提高有关。毫不奇怪,住院时间的延长和年龄的增加会导致更多的镇痛剂处方。要确定阿片类药物处方模式的差异,还需要进一步的调查。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
Journal of opioid management
Journal of opioid management Medicine-Anesthesiology and Pain Medicine
CiteScore
1.00
自引率
0.00%
发文量
54
期刊介绍: The Journal of Opioid Management deals with all aspects of opioids. From basic science, pre-clinical, clinical, abuse, compliance and addiction medicine, the journal provides and unbiased forum for researchers and clinicians to explore and manage the complexities of opioid prescription.
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